Layer- and column-specific knockout of NMDA receptors in pyramidal neurons of the mouse barrel cortex

Frontiers in Integrative Neuroscience

Volumn 1, Issue NOV, 2007, Pages

  Aronoff, Rachel ^a   Petersen, Carl ^a  

^a EPFL   (Switzerland)

Author keywords

Barrel cortex; Cre LoxP; Lentivector; NMDA receptors

Indexed keywords

EID: 84898684427     PISSN: 16625145     EISSN: None     Source Type: Journal    
DOI: 10.3389/neuro.07.001.2007     Document Type: Article

References (60)

1. Abbas-Terki, T., Blanco-Bose, W., Deglon, N., Pralong, W., and Aebischer, P. (2002). Lentiviral-mediated RNA interference. Hum. Gene. Ther. 13, 2197-2201.
2. Ackman, J. B., Siddiqi, F., Walikonis, R. S., and LoTurco, J. J. (2006). Fusion of microglia with pyramidal neurons after retroviral infection. J. Neurosci. 26, 11413-11422.
3. Aronoff, R., and Petersen, C. C. H. (2006). Controlled and localized genetic manipulation in the brain. J. Cell. Mol. Med. 10, 333-352.
4. Bender, V. A., Bender, K. J., Brasier, D. J., and Feldman, D. E. (2006). Two coincidence detectors for spike timing-dependent plasticity in somatosensory cortex. J. Neurosci. 26, 4166-4177.
5. Berger, T., Borgdorff, A. J., Crochet, S., Neubauer, F. B., Lefort, S., Fauvet, B., Ferezou, I., Carleton, A., Luscher, H. R., and Petersen, C. C. H. (2007). Combined voltage and calcium epifluorescence imaging in vitro and in vivo reveals subthreshold and suprathreshold dynamics of mouse barrel cortex. J. Neurophysiol. 97, 3751-3762.
6. Bliss, T. V., and Collingridge, G. L. (1993). A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39.
7. Borgdorff, A. J., Poulet, J. F. A., and Petersen, C. C. H. (2007). Facilitating sensory responses in developing mouse somatosensory barrel cortex. J. Neurophysiol. 97, 2992-3003.
8. Crochet, S., and Petersen, C. C. H. (2006). Correlating whisker behavior with membrane potential in barrel cortex of awake mice. Nat. Neurosci. 9, 608-610.
9. Cull-Candy, S. G., and Leszkiewicz, D. N. (2004). Role of distinct NMDA receptor subtypes at central synapses. Sci. STKE 255, re16.
10. Deglon, N., Tseng, J. L., Bensadoun, J. C., Zurn, A. D., Arsenijevic, Y., Pereira de Almeida, L., Zufferey, R., Trono, D., and Aebischer, P. (2000). Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease. Hum. Gene. Ther. 11, 179-190.
11. Dittgen, T., Nimmerjahn, A., Komai, S., Licznerski, P., Waters, J., Margrie, T. W., Helmchen, F., Denk, W., Brecht, M., and Osten, P. (2004). Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo. Proc. Natl. Acad. Sci. USA 101, 18206-18211.
12. Feil, R., Wagner, J., Metzger, D., and Chambon, P. (1997). Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem. Biophys. Res. Commun. 237, 752-757.
13. Feldman, D. E. (2000). Timing-based LTP and LTD at vertical inputs to layer II/III pyramidal cells in rat barrel cortex. Neuron 27, 45-56.
14. Feldman, D. E., and Brecht, M. (2005). Map plasticity in the somatosensory cortex. Science 310, 810-815.
15. Ferezou, I., Bolea, S., and Petersen, C. C. H. (2006). Visualizing the cortical representation of whisker touch: voltage-sensitive dye imaging in freely moving mice. Neuron 50, 617-629.
16. Ferezou, I., Haiss, F., Gentet, L. J., Aronoff, R., Weber, B., and Petersen, C. C. H. (2007). Spatiotemporal dynamics of cortical sensorimotor integration in behaving mice. Neuron 56, 907-923.
17. Gong, S., Zheng, C., Doughty, M. L., Losos, K., Didkovsky, N., Schambra, U. B., Nowak, N. J., Joyner, A., Leblanc, G., Hatten, M. E., and Heintz, N. (2003). A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature 425, 917-925.
18. Grinvald, A., Lieke, E., Frostig, R. D., Gilbert, C. D., and Wiesel, T. N. (1986). Functional architecture of cortex revealed by optical imaging of intrinsic signals. Nature 324, 361-364.
19. Harris, J. A., Petersen, R. S., and Diamond, M. E. (1999). Distribution of tactile learning and its neural basis. Proc. Natl. Acad. Sci. USA 96, 7587-7591.
20. Hawasli, A. H., Benavides, D. R., Nguyen, C., Kansy, J. W., Hayashi, K., Chambon, P., Greengard, P., Powell, C. M., Cooper, D. C., and Bibb, J. A. (2007). Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation. Nat. Neurosci. 10, 880-886.
21. Hoess, R. H., Ziese, M., and Sternberg, N. (1982). P1 site-specific recombination: nucleotide sequence of the recombining sites. Proc. Natl. Acad. Sci. USA 79, 3398-3402.
22. Hutson, K. A., and Masterton, R. B. (1986). The sensory contribution of a single vibrissa's cortical barrel. J. Neurophysiol. 56, 1196-1223.
23. Iwasato, T., Datwani, A., Wolf, A. M., Nishiyama, H., Taguchi, Y., Tonegawa, S., Knopfel, T., Erzurumlu, R. S., and Itohara, S. (2000). Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex. Nature 406, 726-731.
24. Iwasato, T., Erzurumlu, R. S., Huerta, P. T., Chen, D. F., Sasaoka, T., Ulupinar, E., and Tonegawa, S. (1997). NMDA receptor-dependent refinement of somatotopic maps. Neuron 19, 1201-1210.
25. Kleinfeld, D., Ahissar, E., and Diamond, M. E. (2006). Active sensation: insights from the rodent vibrissa sensorimotor system. Curr. Opin. Neurobiol. 16, 435-444.
26. Köhr, G. (2006). NMDA receptor function: subunit composition versus spatial distribution. Cell Tissue Res. 326, 439-446.
27. Komai, S., Licznerski, P., Cetin, A., Waters, J., Denk, W., Brecht, M., and Osten, P. (2006). Postsynaptic excitability is necessary for strengthening of cortical sensory responses during experience-dependent development. Nat. Neurosci. 9, 1125-1133.
28. Kvajo, M., Albrecht, H., Meins, M., Hengst, U., Troncoso, E., Lefort, S., Kiss, J. Z., Petersen, C. C. H., and Monard, D. (2004). Regulation of brain proteolytic activity is necessary for the in vivo function of NMDA receptors. J. Neurosci. 24, 9734-9743.
29. Laakso, M. M., and Sutton, R. E. (2006). Replicative fidelity of lentiviral vectors produced by transient transfection. Virology 348, 406-417.
30. Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., and Bensinger, A. et al. (2007). Genomewide atlas of gene expression in the adult mouse brain. Nature 445, 168-176.
31. Liu, X.-B., and Jones, E. G. (1996). Localization of alpha type II calcium calmodulindependent protein kinase at glutamatergic but not gama-aminobutyric acid (GABAergic) synapses in thalamus and cerebral cortex. Proc. Natl. Acad. Sci. USA 93, 7332-7336.
32. Mello, C. C., and Conte, D., Jr., (2004). Revealing the world of RNA interference. Nature 431, 338-342.
33. Mori, T., Tanaka, K., Buffo, A., Wurst, W., Kühn, R., and Götz, M. (2006). Inducible gene deletion in astroglia and radial glia-a valuable tool for functional and lineage analysis. Glia 54, 21-34.
34. Naldini, L., Blomer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F. H., Verma, I. M., and Trono, D. (1996). In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267.
35. Petersen, C. C. H. (2003). The barrel cortex-integrating molecular, cellular and systems physiology. Pflugers Arch. 447, 126-134.
36. Petersen, C. C. H. (2007). The functional organization of the barrel cortex. Neuron 56, 339-355.
37. Petersen, C. C. H., and Sakmann, B. (2000). The excitatory neuronal network of rat layer 4 barrel cortex. J. Neurosci. 20, 7579-7586.
38. Petersen, C. C. H., Malenka, R. C., Nicoll, R. A., and Hopfield, J. J. (1998). All-or-none potentiation at CA3-CA1 synapses. Proc. Natl. Acad. Sci. USA 95, 4732-4737.
39. Polley, D. B., Chen-Bee, C. H., and Frostig, R. D. (1999). Two directions of plasticity in the sensory-deprived adult cortex. Neuron 24, 623-637.
40. Rajji, T., Chapman, D., Eichenbaum, H., and Greene, R. (2006). The role of CA3 hippocampal NMDA receptors in paired associate learning. J. Neurosci. 26, 908-915.
41. Rios, M., Fan, G., Fekete, C., Kelly, J., Bates, B., Kuehn, R., Lechan, R. M., and Jaenisch, R. (2001). Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol. Endocrinol. 15, 1748-1757.
42. Sauer, B., and Henderson, N. (1988). Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. USA 85, 5166-5170.
43. Scammell, T. E., Arrigoni, E., Thompson, M. A., Ronan, P. J., Saper, C. B., and Green, R. W. (2003). Focal deletion of the adenosine A1 receptor in adult mice using an adenoassociated viral vector. J. Neurosci. 23, 5762-5770.
44. Shimshek, D. R., Kim, J., Hubner, M. R., Spergel, D. J., Buchholz, F., Casanova, E., Stewart, A. F., Seeburg, P. H., and Sprengel, R. (2002). Codon-improved Cre recombinase (iCre) expression in the mouse. Genesis 32, 19-26.
45. Soriano, P. (1999). Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21, 70-71.
46. Sur, M., and Leamey, C. A. (2001). Development and plasticity of cortical areas and networks. Nat. Rev. Neurosci. 2, 251-262.
47. Szulc, J., Wiznerowicz, M., Sauvain, M. O., Trono, D., and Aebischer, P. (2006). A versatile tool for conditional gene expression and knockdown. Nat. Methods 3, 109-116.
48. Tashiro, A., Sandler, V. M., Toni, N., Zhao, C., and Gage, F. H. (2006). NMDA-receptormediated, cell-specific integration of new neurons in adult dentate gyrus. Nature 442, 929-933.
49. Tsien, J. Z., Chen, D. F., Gerber, D., Tom, C., Mercer, E. H., Anderson, D. J., Mayford, M., Kandel, E. R., and Tonegawa, S. (1996a). Subregion-and cell type-restricted gene knockout in mouse brain. Cell 87, 1317-1326.
50. Tsien, J. Z., Huerta, P. T., and Tonegawa, S. (1996b). The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87, 1327-1338.
51. Walz, A., Rodriguez, I., and Mombaerts, P. (2002). Aberrant sensory innervation of the olfactory bulb in neuropilin-2 mutant mice. J. Neurosci. 22, 4025-4035.
52. Weber, P., Metzger, D., and Chambon, P. (2001). Temporally controlled targeted somatic mutagenesis in the mouse brain. Eur. J. Neurosci. 14, 1777-1783.
53. Wickersham, I. R., Finke, S., Conzelmann, K. K., and Callaway, E. M. (2007a). Retrograde neuronal tracing with a deletion-mutant rabies virus. Nat. Methods 4, 47-49.
54. Wickersham, I. R., Lyon, D. C., Barnard, R. J., Mori, T., Finke, S., Conzelmann, K. K., Young, J. A., and Callaway, E. M. (2007b). Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons. Neuron 53, 639-647.
55. Wong, L. F., Azzouz, M., Walmsley, L. E., Askham, Z., Wilkes, F. J., Mitrophanous, K. A., Kingsman, S. M., and Mazarakis, N. D. (2004). Transduction patterns of pseudotyped lentiviral vectors in the nervous system. Mol. Ther. 9, 101-111.
56. Woolsey, T. A., and Van der Loos, H. (1970). The structural organisation of layer IV in the somatosensory region (SI) of the mouse cerebral cortex: the description of a cortical field composed of discrete cytoarchitectonic units. Brain Res. 17, 205-242.
57. Xu, X., Qiao, W., Li, C., and Deng, C. X. (2002). Generation of Fgfr1 conditional knockout mice. Genesis 32, 85-86.
58. Yu, H., Saura, C. A., Choi, S. Y., Sun, L. D., Yang, X., Handler, M., Kawarabayashi, T., Younkin, L., Fedeles, B., Wilson, M. A., Younkin, S., Kandel, E. R., Kirkwood, A., and Shen, J. (2001). APP processing and synaptic plasticity in presenilin-1 conditional knockout mice. Neuron 31, 713-726.
59. Zhao, M., Li, D., Shimazu, K., Zhou, Y. X., Lu, B., and Deng, C. X. (2007). Fibroblast growth factor receptor-1 is required for long-term-potentiation, memory consolidation and neurogenesis. Biol. Psychiat. 62, 381-390.
60. Zufferey, R., Dull, T., Mandel, R. J., Bukovsky, A., Quiroz, D., Naldini, L., and Trono, D. (1998). Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J. Virol. 72, 9873-9880.