Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Greene, Michael W ^a,b   Burrington, Christine M ^b   Lynch, Darin T ^b   Davenport, Samantha K ^c   Johnson, Andrew K ^b   Horsman, Melissa J ^b   Chowdhry, Saleem ^c   Zhang, Jian ^a   Sparks, Janet D ^d   Tirrell, Paul C ^c  

^a AUBURN UNIVERSITY   (United States)

^b BASSETT RESEARCH INSTITUTE   (United States)

^c BASSETT MEDICAL CENTER   (United States)

^d UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A OXIDASE; ALANINE AMINOTRANSFERASE; CASPASE 3; CASPASE 9; FATTY ACID; GLUCOSE; INSULIN; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE C DELTA; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL CYCLE; CELL DEATH; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; FATTY ACID OXIDATION; FIBROSIS; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HISTOLOGY; INFLAMMATION; INSULIN BLOOD LEVEL; LIPID METABOLISM; LIVER CELL; LIVER WEIGHT; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN CLEAVAGE; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CELLS, CULTURED; CHOLINE DEFICIENCY; DIET; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FATTY LIVER; FEMALE; GENE EXPRESSION; HEPATOCYTES; LIPID METABOLISM; LIVER; LIVER CIRRHOSIS; MALE; METHIONINE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; PRIMARY CELL CULTURE; PROTEIN KINASE C-DELTA;

EID: 84898634376     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085848     Document Type: Article

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