LKB1/AMPK and PKA Control ABCB11 trafficking and polarization in hepatocytes

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Homolya, Laszlo ^a,b   Fu, Dong ^a,c   Sengupta, Prabuddha ^a   Jarnik, Michal ^a   Gillet, Jean Pierre ^d,e   Vitale Cross, Lynn ^f   Gutkind, J Silvio ^f   Lippincott Schwartz, Jennifer ^a   Arias, Irwin M ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c UNIVERSITY OF SYDNEY   (Australia)

^d NATIONAL CANCER INSTITUTE   (United States)

^e University of Namur   (Belgium)

^f NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE SALT EXPORT PUMP; COLLAGEN; CYCLIC AMP; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MYOSIN V; MYOSIN VB; PROTEIN KINASE LKB1; PROTEIN TYROSINE KINASE A; RAB11 PROTEIN; TAUROCHOLIC ACID; UNCLASSIFIED DRUG; ABC TRANSPORTER; ABCB11 PROTEIN, MOUSE; BILE ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; RAB PROTEIN; STK11 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT DISEASE; CELL MIGRATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVITY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE INACTIVATION; GOLGI COMPLEX; INTRACELLULAR SIGNALING; INTRAHEPATIC BILE DUCT; JAUNDICE; LIVER CELL; LIVER CELL CULTURE; LIVER CELL MEMBRANE; MICROTUBULE; MOLECULAR IMAGING; MOUSE; NONHUMAN; POLARIZATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; WEIGHT REDUCTION; ANIMAL; CELL MEMBRANE; CELL POLARITY; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PRIMARY CELL CULTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; CELL MEMBRANE; CELL POLARITY; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENDOSOMES; GENE EXPRESSION REGULATION; GOLGI APPARATUS; HEPATOCYTES; MICE; MICE, KNOCKOUT; MYOSIN TYPE V; PRIMARY CELL CULTURE; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; RAB GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TAUROCHOLIC ACID;

EID: 84898634021     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091921     Document Type: Article

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