Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1- AMPK pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 4, 2011, Pages 1403-1408

  Fu, Dong ^a   Wakabayashi, Yoshiyuki ^a   Lippincott Schwartz, Jennifer ^a   Arias, Irwin M ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Occludin; P glycoprotein; Primary hepatocytes

Indexed keywords

ADENYLATE KINASE; ANTIPORTER; BILE ACID; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; EXCHANGE PROTEIN ACTIVATED BY CAMP; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE LKB1; RAP1 PROTEIN; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BILE ACID SYNTHESIS; CELL POLARITY; ENZYME INHIBITION; INTRAHEPATIC BILE DUCT; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENYLATE KINASE; ANIMALS; BILE ACIDS AND SALTS; BLOTTING, WESTERN; CELL POLARITY; CELLS, CULTURED; CHENODEOXYCHOLIC ACID; CHOLAGOGUES AND CHOLERETICS; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; GREEN FLUORESCENT PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEPATOCYTES; IMINES; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MODELS, BIOLOGICAL; PROTEIN-SERINE-THREONINE KINASES; RAP1 GTP-BINDING PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TAUROCHOLIC ACID; URSODEOXYCHOLIC ACID;

RATTUS;

EID: 79952133231     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018376108     Document Type: Article

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