Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Sharma, Ramaswamy ^a   Callaway, Danielle ^a   Vanegas, Difernando ^a   Bendele, Michelle ^a   Lopez Cruzan, Marisa ^a   Horn, Diane ^a   Guda, Teja ^c   Fajardo, Roberto ^b   Abboud Werner, Sherry ^a   Herman, Brian ^a,d  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c The University of Texas at San Antonio   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ASPARTIC PROTEINASE; CASPASE 2; HYDROGEN PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; 4-HYDROXY-2-NONENAL; ACID PHOSPHATASE; ALDEHYDE; ISOENZYME; SUPEROXIDE DISMUTASE; TARTRATE-RESISTANT ACID PHOSPHATASE;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE DENSITY; BONE FRAGILITY; BONE METABOLISM; BONE STRENGTH; CELL AGING; ENZYME ACTIVITY; FEMUR; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; OXIDATIVE STRESS; PROTEIN EXPRESSION; STEM CELL; WILD TYPE; ANIMAL; BONE; GENETICS; HOMEOSTASIS; METABOLISM; OSTEOPOROSIS; PATHOLOGY;

ACID PHOSPHATASE; ALDEHYDES; ANIMALS; APOPTOSIS; BONE AND BONES; CASPASE 2; HOMEOSTASIS; ISOENZYMES; LIPID PEROXIDATION; MICE; OSTEOCLASTS; OSTEOPOROSIS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84898622905     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093696     Document Type: Article

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