-
1
-
-
0037673945
-
Osteoclast differentiation and activation
-
Boyle, W. J., Simonet, W. S., and Lacey, D. L. (2003) Osteoclast differentiation and activation. Nature 423, 337-3422
-
(2003)
Nature
, vol.423
, pp. 337-3422
-
-
Boyle, W.J.1
Simonet, W.S.2
Lacey, D.L.3
-
2
-
-
70349100754
-
Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation
-
Negishi-Koga, T., and Takayanagi, H. (2009) Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation. Immunol. Rev. 231, 241-2566
-
(2009)
Immunol. Rev.
, vol.231
, pp. 241-2566
-
-
Negishi-Koga, T.1
Takayanagi, H.2
-
3
-
-
33744752099
-
Molecular mechanism of the life and death of the osteoclast
-
Tanaka, S., Miyazaki, T., Fukuda, A., Akiyama, T., Kadono, Y., Wakeyama, H., Kono, S., Hoshikawa, S., Nakamura, M., Ohshima, Y., Hikita, A., Nakamura, I., and Nakamura, K. (2006) Molecular mechanism of the life and death of the osteoclast. Ann. N.Y. Acad. Sci. 1068, 180-1866
-
(2006)
Ann. N.Y. Acad. Sci.
, vol.1068
, pp. 180-1866
-
-
Tanaka, S.1
Miyazaki, T.2
Fukuda, A.3
Akiyama, T.4
Kadono, Y.5
Wakeyama, H.6
Kono, S.7
Hoshikawa, S.8
Nakamura, M.9
Ohshima, Y.10
Hikita, A.11
Nakamura, I.12
Nakamura, K.13
-
4
-
-
10744232926
-
Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim
-
Akiyama, T., Bouillet, P., Miyazaki, T., Kadono, Y., Chikuda, H., Chung, U. I., Fukuda, A., Hikita, A., Seto, H., Okada, T., Inaba, T., Sanjay, A., Baron, R., Kawaguchi, H., Oda, H., Nakamura, K., Strasser, A., and Tanaka, S. (2003) Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim. EMBO J. 22, 6653-66644
-
(2003)
EMBO J.
, vol.22
, pp. 6653-66644
-
-
Akiyama, T.1
Bouillet, P.2
Miyazaki, T.3
Kadono, Y.4
Chikuda, H.5
Chung, U.I.6
Fukuda, A.7
Hikita, A.8
Seto, H.9
Okada, T.10
Inaba, T.11
Sanjay, A.12
Baron, R.13
Kawaguchi, H.14
Oda, H.15
Nakamura, K.16
Strasser, A.17
Tanaka, S.18
-
5
-
-
70349668936
-
The antiapoptotic protein Bcl-xL negatively regulates the bone-resorbing activity of osteoclasts in mice
-
Iwasawa, M., Miyazaki, T., Nagase, Y., Akiyama, T., Kadono, Y., Nakamura, M., Oshima, Y., Yasui, T., Matsumoto, T., Nakamura, T., Kato, S., Hennighausen, L., Nakamura, K., and Tanaka, S. (2009) The antiapoptotic protein Bcl-xL negatively regulates the bone-resorbing activity of osteoclasts in mice. J. Clin. Invest. 119, 3149-31599
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3149-31599
-
-
Iwasawa, M.1
Miyazaki, T.2
Nagase, Y.3
Akiyama, T.4
Kadono, Y.5
Nakamura, M.6
Oshima, Y.7
Yasui, T.8
Matsumoto, T.9
Nakamura, T.10
Kato, S.11
Hennighausen, L.12
Nakamura, K.13
Tanaka, S.14
-
6
-
-
0034764244
-
Purinergic signaling: ATP release
-
Bodin, P., and Burnstock, G. (2001) Purinergic signaling: ATP release. Neurochem. Res. 26, 959-9699
-
(2001)
Neurochem. Res.
, vol.26
, pp. 959-9699
-
-
Bodin, P.1
Burnstock, G.2
-
7
-
-
0036118418
-
Purinergic signaling and vascular cell proliferation and death
-
Burnstock, G. (2002) Purinergic signaling and vascular cell proliferation and death. Arterioscler. Thromb. Vasc. Biol. 22, 364-3733
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, pp. 364-3733
-
-
Burnstock, G.1
-
8
-
-
38649107374
-
Maintenance of mitochondrial DNA copy number and expression are essential for preservation of mitochondrial function and cell growth
-
Jeng, J. Y., Yeh, T. S., Lee, J. W., Lin, S. H., Fong, T. H., and Hsieh, R. H. (2008) Maintenance of mitochondrial DNA copy number and expression are essential for preservation of mitochondrial function and cell growth. J. Cell. Biochem. 103, 347-3577
-
(2008)
J. Cell. Biochem.
, vol.103
, pp. 347-3577
-
-
Jeng, J.Y.1
Yeh, T.S.2
Lee, J.W.3
Lin, S.H.4
Fong, T.H.5
Hsieh, R.H.6
-
9
-
-
80051970600
-
Metabolic regulation of protein N-α-acetylation by Bcl-xL promotes cell survival
-
Yi, C. H., Pan, H., Seebacher, J., Jang, I. H., Hyberts, S. G., Heffron, G. J., Vander Heiden, M. G., Yang, R., Li, F., Locasale, J. W., Sharfi, H., Zhai, B., Rodriguez-Mias, R., Luithardt, H., Cantley, L. C., Daley, G. Q., Asara, J. M., Gygi, S. P., Wagner, G., Liu, C. F., and Yuan, J. (2011) Metabolic regulation of protein N-α-acetylation by Bcl-xL promotes cell survival. Cell 146, 607-6200
-
(2011)
Cell
, vol.146
, pp. 607-6200
-
-
Yi, C.H.1
Pan, H.2
Seebacher, J.3
Jang, I.H.4
Hyberts, S.G.5
Heffron, G.J.6
Vander Heiden, M.G.7
Yang, R.8
Li, F.9
Locasale, J.W.10
Sharfi, H.11
Zhai, B.12
Rodriguez-Mias, R.13
Luithardt, H.14
Cantley, L.C.15
Daley, G.Q.16
Asara, J.M.17
Gygi, S.P.18
Wagner, G.19
Liu, C.F.20
Yuan, J.21
more..
-
10
-
-
0033000804
-
Partial ATP depletion induces Fas-and caspase-mediated apoptosis in MDCK cells
-
Feldenberg, L. R., Thevananther, S., del Rio, M., de Leon, M., and Devarajan, P. (1999) Partial ATP depletion induces Fas-and caspase-mediated apoptosis in MDCK cells. Am. J. Physiol. 276, F837-8466
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Feldenberg, L.R.1
Thevananther, S.2
Del Rio, M.3
De Leon, M.4
Devarajan, P.5
-
11
-
-
9644268985
-
The transcription machinery in mammalian mitochondria
-
Gaspari, M., Larsson, N. G., and Gustafsson, C. M. (2004) The transcription machinery in mammalian mitochondria. Biochim. Biophys. Acta 1659, 148-1522
-
(2004)
Biochim. Biophys. Acta
, vol.1659
, pp. 148-1522
-
-
Gaspari, M.1
Larsson, N.G.2
Gustafsson, C.M.3
-
12
-
-
0026671245
-
Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease
-
Corral-Debrinski, M., Shoffner, J. M., Lott, M. T., and Wallace, D. C. (1992) Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease. Mutat. Res. 275, 169-1800
-
(1992)
Mutat. Res.
, vol.275
, pp. 169-1800
-
-
Corral-Debrinski, M.1
Shoffner, J.M.2
Lott, M.T.3
Wallace, D.C.4
-
13
-
-
0031930319
-
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
-
Larsson, N. G., Wang, J., Wilhelmsson, H., Oldfors, A., Rustin, P., Lewandoski, M., Barsh, G. S., and Clayton, D. A. (1998) Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat. Genet. 18, 231-2366
-
(1998)
Nat. Genet.
, vol.18
, pp. 231-2366
-
-
Larsson, N.G.1
Wang, J.2
Wilhelmsson, H.3
Oldfors, A.4
Rustin, P.5
Lewandoski, M.6
Barsh, G.S.7
Clayton, D.A.8
-
14
-
-
2442431673
-
Mitochondrial transcription factor A regulates mtDNA copy number in mammals
-
Ekstrand, M. I., Falkenberg, M., Rantanen, A., Park, C. B., Gaspari, M., Hultenby, K., Rustin, P., Gustafsson, C. M., and Larsson, N. G. (2004) Mitochondrial transcription factor A regulates mtDNA copy number in mammals. Hum. Mol. Genet 13, 935-9444
-
(2004)
Hum. Mol. Genet
, vol.13
, pp. 935-9444
-
-
Ekstrand, M.I.1
Falkenberg, M.2
Rantanen, A.3
Park, C.B.4
Gaspari, M.5
Hultenby, K.6
Rustin, P.7
Gustafsson, C.M.8
Larsson, N.G.9
-
15
-
-
0036648997
-
Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA
-
Falkenberg, M., Gaspari, M., Rantanen, A., Trifunovic, A., Larsson, N. G., and Gustafsson, C. M. (2002) Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA. Nat. Genet. 31, 289-2944
-
(2002)
Nat. Genet.
, vol.31
, pp. 289-2944
-
-
Falkenberg, M.1
Gaspari, M.2
Rantanen, A.3
Trifunovic, A.4
Larsson, N.G.5
Gustafsson, C.M.6
-
16
-
-
0032924872
-
Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression
-
Wang, J., Wilhelmsson, H., Graff, C., Li, H., Oldfors, A., Rustin, P., Brüning, J. C., Kahn, C. R., Clayton, D. A., Barsh, G. S., Thorén, P., and Larsson, N. G. (1999) Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression. Nat. Genet. 21, 133-1377
-
(1999)
Nat. Genet.
, vol.21
, pp. 133-1377
-
-
Wang, J.1
Wilhelmsson, H.2
Graff, C.3
Li, H.4
Oldfors, A.5
Rustin, P.6
Brüning, J.C.7
Kahn, C.R.8
Clayton, D.A.9
Barsh, G.S.10
Thorén, P.11
Larsson, N.G.12
-
17
-
-
0034724327
-
Genetic modification of survival in tissuespecific knockout mice with mitochondrial cardiomyopathy
-
Li, H., Wang, J., Wilhelmsson, H., Hansson, A., Thoren, P., Duffy, J., Rustin, P., and Larsson, N. G. (2000) Genetic modification of survival in tissuespecific knockout mice with mitochondrial cardiomyopathy. Proc. Natl. Acad. Sci. U.S.A. 97, 3467-34722
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 3467-34722
-
-
Li, H.1
Wang, J.2
Wilhelmsson, H.3
Hansson, A.4
Thoren, P.5
Duffy, J.6
Rustin, P.7
Larsson, N.G.8
-
18
-
-
34548274444
-
Estrogen prevents bone loss via estrogen receptor α and induction of Fas ligand in osteoclasts
-
Nakamura, T., Imai, Y., Matsumoto, T., Sato, S., Takeuchi, K., Igarashi, K., Harada, Y., Azuma, Y., Krust, A., Yamamoto, Y., Nishina, H., Takeda, S., Takayanagi, H., Metzger, D., Kanno, J., Takaoka, K., Martin, T. J., Chambon, P., and Kato, S. (2007) Estrogen prevents bone loss via estrogen receptor α and induction of Fas ligand in osteoclasts. Cell 130, 811-8233
-
(2007)
Cell
, vol.130
, pp. 811-8233
-
-
Nakamura, T.1
Imai, Y.2
Matsumoto, T.3
Sato, S.4
Takeuchi, K.5
Igarashi, K.6
Harada, Y.7
Azuma, Y.8
Krust, A.9
Yamamoto, Y.10
Nishina, H.11
Takeda, S.12
Takayanagi, H.13
Metzger, D.14
Kanno, J.15
Takaoka, K.16
Martin, T.J.17
Chambon, P.18
Kato, S.19
-
19
-
-
0037634326
-
Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption
-
Ke, H. Z., Qi, H., Weidema, A. F., Zhang, Q., Panupinthu, N., Crawford, D. T., Grasser, W. A., Paralkar, V. M., Li, M., Audoly, L. P., Gabel, C. A., Jee, W. S., Dixon, S. J., Sims, S. M., and Thompson, D. D. (2003) Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption. Mol. Endocrinol. 17, 1356-13677
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 1356-13677
-
-
Ke, H.Z.1
Qi, H.2
Weidema, A.F.3
Zhang, Q.4
Panupinthu, N.5
Crawford, D.T.6
Grasser, W.A.7
Paralkar, V.M.8
Li, M.9
Audoly, L.P.10
Gabel, C.A.11
Jee, W.S.12
Dixon, S.J.13
Sims, S.M.14
Thompson, D.D.15
-
20
-
-
0023790708
-
Osteoblastic cells are involved in osteoclast formation
-
Takahashi, N., Akatsu, T., Udagawa, N., Sasaki, T., Yamaguchi, A., Moseley, J. M., Martin, T. J., and Suda, T. (1988) Osteoblastic cells are involved in osteoclast formation. Endocrinology 123, 2600-26022
-
(1988)
Endocrinology
, vol.123
, pp. 2600-26022
-
-
Takahashi, N.1
Akatsu, T.2
Udagawa, N.3
Sasaki, T.4
Yamaguchi, A.5
Moseley, J.M.6
Martin, T.J.7
Suda, T.8
-
21
-
-
0034707671
-
Reciprocal role of ERK and NF-κB pathways in survival and activation of osteoclasts
-
Miyazaki, T., Katagiri, H., Kanegae, Y., Takayanagi, H., Sawada, Y., Yamamoto, A., Pando, M. P., Asano, T., Verma, I. M., Oda, H., Nakamura, K., and Tanaka, S. (2000) Reciprocal role of ERK and NF-κB pathways in survival and activation of osteoclasts. J. Cell Biol. 148, 333-3422
-
(2000)
J. Cell Biol.
, vol.148
, pp. 333-3422
-
-
Miyazaki, T.1
Katagiri, H.2
Kanegae, Y.3
Takayanagi, H.4
Sawada, Y.5
Yamamoto, A.6
Pando, M.P.7
Asano, T.8
Verma, I.M.9
Oda, H.10
Nakamura, K.11
Tanaka, S.12
-
22
-
-
55549132659
-
Pivotal role of Bcl-2 family proteins in the regulation of chondrocyte apoptosis
-
Oshima, Y., Akiyama, T., Hikita, A., Iwasawa, M., Nagase, Y., Nakamura, M., Wakeyama, H., Kawamura, N., Ikeda, T., Chung, U. I., Hennighausen, L., Kawaguchi, H., Nakamura, K., and Tanaka, S. (2008) Pivotal role of Bcl-2 family proteins in the regulation of chondrocyte apoptosis. J. Biol. Chem. 283, 26499-265088
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 26499-265088
-
-
Oshima, Y.1
Akiyama, T.2
Hikita, A.3
Iwasawa, M.4
Nagase, Y.5
Nakamura, M.6
Wakeyama, H.7
Kawamura, N.8
Ikeda, T.9
Chung, U.I.10
Hennighausen, L.11
Kawaguchi, H.12
Nakamura, K.13
Tanaka, S.14
-
23
-
-
25444434069
-
In vitro and in vivo assays for osteoclast apoptosis
-
Akiyama, T., Miyazaki, T., Bouillet, P., Nakamura, K., Strasser, A., and Tanaka, S. (2005) In vitro and in vivo assays for osteoclast apoptosis. Biol. Proced. Online 7, 48-599
-
(2005)
Biol. Proced. Online
, vol.7
, pp. 48-599
-
-
Akiyama, T.1
Miyazaki, T.2
Bouillet, P.3
Nakamura, K.4
Strasser, A.5
Tanaka, S.6
-
24
-
-
0037128202
-
Force transduction by Triton cytoskeletons
-
Sawada, Y., and Sheetz, M. P. (2002) Force transduction by Triton cytoskeletons. J. Cell Biol. 156, 609-6155
-
(2002)
J. Cell Biol.
, vol.156
, pp. 609-6155
-
-
Sawada, Y.1
Sheetz, M.P.2
-
25
-
-
33751335857
-
Force sensing by mechanical extension of the Src family kinase substrate p130Cas
-
Sawada, Y., Tamada, M., Dubin-Thaler, B. J., Cherniavskaya, O., Sakai, R., Tanaka, S., and Sheetz, M. P. (2006) Force sensing by mechanical extension of the Src family kinase substrate p130Cas. Cell 127, 1015-10266
-
(2006)
Cell
, vol.127
, pp. 1015-10266
-
-
Sawada, Y.1
Tamada, M.2
Dubin-Thaler, B.J.3
Cherniavskaya, O.4
Sakai, R.5
Tanaka, S.6
Sheetz, M.P.7
-
26
-
-
65549133193
-
Hypoxia stimulates vesicular ATP release from rat osteoblasts
-
Orriss, I. R., Knight, G. E., Utting, J. C., Taylor, S. E., Burnstock, G., and Arnett, T. R. (2009) Hypoxia stimulates vesicular ATP release from rat osteoblasts. J. Cell Physiol. 220, 155-1622
-
(2009)
J. Cell Physiol.
, vol.220
, pp. 155-1622
-
-
Orriss, I.R.1
Knight, G.E.2
Utting, J.C.3
Taylor, S.E.4
Burnstock, G.5
Arnett, T.R.6
-
27
-
-
77951737783
-
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations
-
Chen, H., Vermulst, M., Wang, Y. E., Chomyn, A., Prolla, T. A., McCaffery, J. M., and Chan, D. C. (2010) Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations. Cell 141, 280-2899
-
(2010)
Cell
, vol.141
, pp. 280-2899
-
-
Chen, H.1
Vermulst, M.2
Wang, Y.E.3
Chomyn, A.4
Prolla, T.A.5
McCaffery, J.M.6
Chan, D.C.7
-
28
-
-
80053560844
-
Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase
-
Alavian, K. N., Li, H., Collis, L., Bonanni, L., Zeng, L., Sacchetti, S., Lazrove, E., Nabili, P., Flaherty, B., Graham, M., Chen, Y., Messerli, S. M., Mariggio, M. A., Rahner, C., McNay, E., Shore, G. C., Smith, P. J., Hardwick, J. M., and Jonas, E. A. (2011) Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase. Nat. Cell Biol. 13, 1224-12333
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1224-12333
-
-
Alavian, K.N.1
Li, H.2
Collis, L.3
Bonanni, L.4
Zeng, L.5
Sacchetti, S.6
Lazrove, E.7
Nabili, P.8
Flaherty, B.9
Graham, M.10
Chen, Y.11
Messerli, S.M.12
Mariggio, M.A.13
Rahner, C.14
McNay, E.15
Shore, G.C.16
Smith, P.J.17
Hardwick, J.M.18
Jonas, E.A.19
-
29
-
-
80355146535
-
Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential
-
Chen, Y. B., Aon, M. A., Hsu, Y. T., Soane, L., Teng, X., McCaffery, J. M., Cheng, W. C., Qi, B., Li, H., Alavian, K. N., Dayhoff-Brannigan, M., Zou, S., Pineda, F. J., O'Rourke, B., Ko, Y. H., Pedersen, P. L., Kaczmarek, L. K., Jonas, E. A., and Hardwick, J. M. (2011) Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential. J. Cell Biol. 195, 263-2766
-
(2011)
J. Cell Biol.
, vol.195
, pp. 263-2766
-
-
Chen, Y.B.1
Aon, M.A.2
Hsu, Y.T.3
Soane, L.4
Teng, X.5
McCaffery, J.M.6
Cheng, W.C.7
Qi, B.8
Li, H.9
Alavian, K.N.10
Dayhoff-Brannigan, M.11
Zou, S.12
Pineda, F.J.13
O'Rourke, B.14
Ko, Y.H.15
Pedersen, P.L.16
Kaczmarek, L.K.17
Jonas, E.A.18
Hardwick, J.M.19
-
30
-
-
0037416134
-
Regulation of cytochrome c oxidase activity by c-Src in osteoclasts
-
Miyazaki, T., Neff, L., Tanaka, S., Horne, W. C., and Baron, R. (2003) Regulation of cytochrome c oxidase activity by c-Src in osteoclasts. J. Cell Biol. 160, 709-7188
-
(2003)
J. Cell Biol.
, vol.160
, pp. 709-7188
-
-
Miyazaki, T.1
Neff, L.2
Tanaka, S.3
Horne, W.C.4
Baron, R.5
-
31
-
-
73649107266
-
Antiapoptotic molecule Bcl-2 regulates the differentiation, activation, and survival of both osteoblasts and osteoclasts
-
Nagase, Y., Iwasawa, M., Akiyama, T., Kadono, Y., Nakamura, M., Oshima, Y., Yasui, T., Matsumoto, T., Hirose, J., Nakamura, H., Miyamoto, T., Bouillet, P., Nakamura, K., and Tanaka, S. (2009) Antiapoptotic molecule Bcl-2 regulates the differentiation, activation, and survival of both osteoblasts and osteoclasts. J. Biol. Chem. 284, 36659-366699
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 36659-366699
-
-
Nagase, Y.1
Iwasawa, M.2
Akiyama, T.3
Kadono, Y.4
Nakamura, M.5
Oshima, Y.6
Yasui, T.7
Matsumoto, T.8
Hirose, J.9
Nakamura, H.10
Miyamoto, T.11
Bouillet, P.12
Nakamura, K.13
Tanaka, S.14
-
32
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
-
Takayanagi, H., Kim, S., Koga, T., Nishina, H., Isshiki, M., Yoshida, H., Saiura, A., Isobe, M., Yokochi, T., Inoue, J., Wagner, E. F., Mak, T. W., Kodama, T., and Taniguchi, T. (2002) Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev. Cell 3, 889-9011
-
(2002)
Dev. Cell
, vol.3
, pp. 889-9011
-
-
Takayanagi, H.1
Kim, S.2
Koga, T.3
Nishina, H.4
Isshiki, M.5
Yoshida, H.6
Saiura, A.7
Isobe, M.8
Yokochi, T.9
Inoue, J.10
Wagner, E.F.11
Mak, T.W.12
Kodama, T.13
Taniguchi, T.14
-
33
-
-
84864451590
-
Cathepsin K-Cre causes unexpected germline deletion of genes in mice
-
Winkeler, C. L., Kladney, R. D., Maggi, L. B., Jr., and Weber, J. D. (2012) Cathepsin K-Cre causes unexpected germline deletion of genes in mice. PLoS One 7, e420055
-
(2012)
PLoS One
, vol.7
-
-
Winkeler, C.L.1
Kladney, R.D.2
Maggi Jr., L.B.3
Weber, J.D.4
-
34
-
-
0035957398
-
Increased in vivo apoptosis in cells lacking mitochondrial DNA gene expression
-
Wang, J., Silva, J. P., Gustafsson, C. M., Rustin, P., and Larsson, N. G. (2001) Increased in vivo apoptosis in cells lacking mitochondrial DNA gene expression. Proc. Natl. Acad. Sci. U.S.A. 98, 4038-40433
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 4038-40433
-
-
Wang, J.1
Silva, J.P.2
Gustafsson, C.M.3
Rustin, P.4
Larsson, N.G.5
-
35
-
-
0344081177
-
Minireview: The AMP-activated protein kinase cascade: The key sensor of cellular energy status
-
Hardie, D. G. (2003) Minireview: The AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology 144, 5179-51833
-
(2003)
Endocrinology
, vol.144
, pp. 5179-51833
-
-
Hardie, D.G.1
-
36
-
-
0043011159
-
Extracellular ATP as a signaling molecule for epithelial cells
-
Schwiebert, E. M., and Zsembery, A. (2003) Extracellular ATP as a signaling molecule for epithelial cells. Biochim. Biophys. Acta 1615, 7-322
-
(2003)
Biochim. Biophys. Acta
, vol.1615
, pp. 7-322
-
-
Schwiebert, E.M.1
Zsembery, A.2
-
37
-
-
33845708770
-
ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors
-
Chen, Y., Corriden, R., Inoue, Y., Yip, L., Hashiguchi, N., Zinkernagel, A., Nizet, V., Insel, P. A., and Junger, W. G. (2006) ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science 314, 1792-17955
-
(2006)
Science
, vol.314
, pp. 1792-17955
-
-
Chen, Y.1
Corriden, R.2
Inoue, Y.3
Yip, L.4
Hashiguchi, N.5
Zinkernagel, A.6
Nizet, V.7
Insel, P.A.8
Junger, W.G.9
-
38
-
-
12444290153
-
Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells
-
Morelli, A., Chiozzi, P., Chiesa, A., Ferrari, D., Sanz, J. M., Falzoni, S., Pinton, P., Rizzuto, R., Olson, M. F., and Di Virgilio, F. (2003) Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells. Mol. Biol. Cell 14, 2655-26644
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 2655-26644
-
-
Morelli, A.1
Chiozzi, P.2
Chiesa, A.3
Ferrari, D.4
Sanz, J.M.5
Falzoni, S.6
Pinton, P.7
Rizzuto, R.8
Olson, M.F.9
Di Virgilio, F.10
-
39
-
-
70349644971
-
Role of purinergic receptor in fodrin degradation in Par C5 cells
-
Hwang, S. M., Li, J., Koo, N. Y., Choi, S. Y., Lee, S. J., Oh, S. B., Castro, R., Kim, J. S., and Park, K. (2009) Role of purinergic receptor in fodrin degradation in Par C5 cells. J. Dent. Res. 88, 927-9322
-
(2009)
J. Dent. Res.
, vol.88
, pp. 927-9322
-
-
Hwang, S.M.1
Li, J.2
Koo, N.Y.3
Choi, S.Y.4
Lee, S.J.5
Oh, S.B.6
Castro, R.7
Kim, J.S.8
Park, K.9
-
40
-
-
0028934919
-
Proteolysis of fodrin (nonerythroid spectrin) during apoptosis
-
Martin, S. J., O'Brien, G. A., Nishioka, W. K., McGahon, A. J., Mahboubi, A., Saido, T. C., and Green, D. R. (1995) Proteolysis of fodrin (nonerythroid spectrin) during apoptosis. J. Biol. Chem. 270, 6425-64288
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6425-64288
-
-
Martin, S.J.1
O'Brien, G.A.2
Nishioka, W.K.3
McGahon, A.J.4
Mahboubi, A.5
Saido, T.C.6
Green, D.R.7
-
41
-
-
23044501272
-
A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death
-
Auger, R., Motta, I., Benihoud, K., Ojcius, D. M., and Kanellopoulos, J. M. (2005) A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death. J. Biol. Chem. 280, 28142-281511
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28142-281511
-
-
Auger, R.1
Motta, I.2
Benihoud, K.3
Ojcius, D.M.4
Kanellopoulos, J.M.5
-
42
-
-
53449102024
-
P2X7 receptor-Pannexin 1 complex: Pharmacology and signaling
-
Iglesias, R., Locovei, S., Roque, A., Alberto, A. P., Dahl, G., Spray, D. C., and Scemes, E. (2008) P2X7 receptor-Pannexin 1 complex: pharmacology and signaling. Am. J. Physiol. Cell Physiol. 295, C752-C7600
-
(2008)
Am. J. Physiol. Cell Physiol.
, vol.295
-
-
Iglesias, R.1
Locovei, S.2
Roque, A.3
Alberto, A.P.4
Dahl, G.5
Spray, D.C.6
Scemes, E.7
-
43
-
-
79954583662
-
P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration
-
Pellegatti, P., Falzoni, S., Donvito, G., Lemaire, I., and Di Virgilio, F. (2011) P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration. FASEB J. 25, 1264-12744
-
(2011)
FASEB J.
, vol.25
, pp. 1264-12744
-
-
Pellegatti, P.1
Falzoni, S.2
Donvito, G.3
Lemaire, I.4
Di Virgilio, F.5
-
44
-
-
0026587335
-
Mitochondrial genetics: A paradigm for aging and degenerative diseases?
-
Wallace, D. C. (1992) Mitochondrial genetics: a paradigm for aging and degenerative diseases? Science 256, 628-6322
-
(1992)
Science
, vol.256
, pp. 628-6322
-
-
Wallace, D.C.1
-
45
-
-
0034602958
-
Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart
-
Barazzoni, R., Short, K. R., and Nair, K. S. (2000) Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart. J. Biol. Chem. 275, 3343-33477
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3343-33477
-
-
Barazzoni, R.1
Short, K.R.2
Nair, K.S.3
-
46
-
-
0035999437
-
Changes in bone structure and mass with advancing age in the male C57BL/6J mouse
-
Halloran, B. P., Ferguson, V. L., Simske, S. J., Burghardt, A., Venton, L. L., and Majumdar, S. (2002) Changes in bone structure and mass with advancing age in the male C57BL/6J mouse. J. Bone Miner Res. 17, 1044-10500
-
(2002)
J. Bone Miner Res.
, vol.17
, pp. 1044-10500
-
-
Halloran, B.P.1
Ferguson, V.L.2
Simske, S.J.3
Burghardt, A.4
Venton, L.L.5
Majumdar, S.6
-
47
-
-
82455210399
-
Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: Role of the Akt pathway and the ERK/Bim axis
-
Matsumoto, T., Nagase, Y., Iwasawa, M., Yasui, T., Masuda, H., Kadono, Y., Nakamura, K., and Tanaka, S. (2011) Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: role of the Akt pathway and the ERK/Bim axis. Arthritis Rheum. 63, 3908-39177
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 3908-39177
-
-
Matsumoto, T.1
Nagase, Y.2
Iwasawa, M.3
Yasui, T.4
Masuda, H.5
Kadono, Y.6
Nakamura, K.7
Tanaka, S.8
-
48
-
-
3543046206
-
Wages of fear: Transient threefold decrease in intracellular ATP level imposes apoptosis
-
Izyumov, D. S., Avetisyan, A. V., Pletjushkina, O. Y., Sakharov, D. V., Wirtz, K. W., Chernyak, B. V., and Skulachev, V. P. (2004) "Wages of fear": transient threefold decrease in intracellular ATP level imposes apoptosis. Biochim. Biophys. Acta 1658, 141-1477
-
(2004)
Biochim. Biophys. Acta
, vol.1658
, pp. 141-1477
-
-
Izyumov, D.S.1
Avetisyan, A.V.2
Pletjushkina, O.Y.3
Sakharov, D.V.4
Wirtz, K.W.5
Chernyak, B.V.6
Skulachev, V.P.7
-
49
-
-
0034194652
-
Integrins and signaling in osteoclast function
-
Duong, L. T., Lakkakorpi, P., Nakamura, I., and Rodan, G. A. (2000) Integrins and signaling in osteoclast function. Matrix Biol. 19, 97-1055
-
(2000)
Matrix Biol.
, vol.19
, pp. 97-1055
-
-
Duong, L.T.1
Lakkakorpi, P.2
Nakamura, I.3
Rodan, G.A.4
-
50
-
-
34548845081
-
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2-/-mice
-
Gil-Henn, H., Destaing, O., Sims, N. A., Aoki, K., Alles, N., Neff, L., Sanjay, A., Bruzzaniti, A., De Camilli, P., Baron, R., and Schlessinger, J. (2007) Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2-/-mice. J. Cell Biol. 178, 1053-10644
-
(2007)
J. Cell Biol.
, vol.178
, pp. 1053-10644
-
-
Gil-Henn, H.1
Destaing, O.2
Sims, N.A.3
Aoki, K.4
Alles, N.5
Neff, L.6
Sanjay, A.7
Bruzzaniti, A.8
De Camilli, P.9
Baron, R.10
Schlessinger, J.11
-
51
-
-
0023024982
-
Intracellular compartmentalization of adenosine triphosphate
-
Miller, D. S., and Horowitz, S. B. (1986) Intracellular compartmentalization of adenosine triphosphate. J. Biol. Chem. 261, 13911-139155
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 13911-139155
-
-
Miller, D.S.1
Horowitz, S.B.2
-
52
-
-
79953175572
-
Nonsynaptic and nonvesicular ATP release from neurons and relevance to neuron-glia signaling
-
Fields, R. D. (2011) Nonsynaptic and nonvesicular ATP release from neurons and relevance to neuron-glia signaling. Semin. Cell Dev. Biol. 22, 214-2199
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 214-2199
-
-
Fields, R.D.1
-
54
-
-
33751572168
-
Pannexin 1 is expressed by neurons and glia but does not form functional gap junctions
-
Huang, Y., Grinspan, J. B., Abrams, C. K., and Scherer, S. S. (2007) Pannexin 1 is expressed by neurons and glia but does not form functional gap junctions. Glia 55, 46-566
-
(2007)
Glia
, vol.55
, pp. 46-566
-
-
Huang, Y.1
Grinspan, J.B.2
Abrams, C.K.3
Scherer, S.S.4
-
55
-
-
35748965595
-
Pannexin 1 channels contain a glycosylation site that targets the hexamer to the plasma membrane
-
Boassa, D., Ambrosi, C., Qiu, F., Dahl, G., Gaietta, G., and Sosinsky, G. (2007) Pannexin 1 channels contain a glycosylation site that targets the hexamer to the plasma membrane. J. Biol. Chem. 282, 31733-317433
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 31733-317433
-
-
Boassa, D.1
Ambrosi, C.2
Qiu, F.3
Dahl, G.4
Gaietta, G.5
Sosinsky, G.6
-
56
-
-
75749152627
-
Non-junction functions of pannexin 1 channels
-
MacVicar, B. A., and Thompson, R. J. (2010) Non-junction functions of pannexin 1 channels. Trends Neurosci. 33, 93-1022
-
(2010)
Trends Neurosci.
, vol.33
, pp. 93-1022
-
-
MacVicar, B.A.1
Thompson, R.J.2
-
57
-
-
67649460727
-
ATPinduced osteoclast function: The formation of sealing-zone like structure and the secretion of lytic granules via microtubule-deacetylation under the control of Syk
-
Hazama, R., Qu, X., Yokoyama, K., Tanaka, C., Kinoshita, E., He, J., Takahashi, S., Tohyama, K., Yamamura, H., and Tohyama, Y. (2009) ATPinduced osteoclast function: the formation of sealing-zone like structure and the secretion of lytic granules via microtubule-deacetylation under the control of Syk. Genes Cells 14, 871-8844
-
(2009)
Genes Cells
, vol.14
, pp. 871-8844
-
-
Hazama, R.1
Qu, X.2
Yokoyama, K.3
Tanaka, C.4
Kinoshita, E.5
He, J.6
Takahashi, S.7
Tohyama, K.8
Yamamura, H.9
Tohyama, Y.10
-
58
-
-
58549115903
-
Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate
-
Pederson, L., Ruan, M., Westendorf, J. J., Khosla, S., and Oursler, M. J. (2008) Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate. Proc. Natl. Acad. Sci. U.S.A. 105, 20764-207699
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 20764-207699
-
-
Pederson, L.1
Ruan, M.2
Westendorf, J.J.3
Khosla, S.4
Oursler, M.J.5
-
59
-
-
44649092795
-
P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: A signaling axis promoting osteogenesis
-
Panupinthu, N., Rogers, J. T., Zhao, L., Solano-Flores, L. P., Possmayer, F., Sims, S. M., and Dixon, S. J. (2008) P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis. J. Cell Biol. 181, 859-8711
-
(2008)
J. Cell Biol.
, vol.181
, pp. 859-8711
-
-
Panupinthu, N.1
Rogers, J.T.2
Zhao, L.3
Solano-Flores, L.P.4
Possmayer, F.5
Sims, S.M.6
Dixon, S.J.7
-
60
-
-
21644466461
-
Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts
-
Genetos, D. C., Geist, D. J., Liu, D., Donahue, H. J., and Duncan, R. L. (2005) Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts. J. Bone Miner. Res. 20, 41-499
-
(2005)
J. Bone Miner. Res.
, vol.20
, pp. 41-499
-
-
Genetos, D.C.1
Geist, D.J.2
Liu, D.3
Donahue, H.J.4
Duncan, R.L.5
-
61
-
-
80051792845
-
Activation of the PI3K/Akt signaling pathway through P2Y2 receptors by extracellular ATP is involved in osteoblastic cell proliferation
-
Katz, S., Ayala, V., Santillán, G., and Boland, R. (2011) Activation of the PI3K/Akt signaling pathway through P2Y2 receptors by extracellular ATP is involved in osteoblastic cell proliferation. Arch. Biochem. Biophys. 513, 144-1522
-
(2011)
Arch. Biochem. Biophys.
, vol.513
, pp. 144-1522
-
-
Katz, S.1
Ayala, V.2
Santillán, G.3
Boland, R.4
-
62
-
-
30044443068
-
The P2X7 nucleotide receptor mediates skeletal mechanotransduction
-
Li, J., Liu, D., Ke, H. Z., Duncan, R. L., and Turner, C. H. (2005) The P2X7 nucleotide receptor mediates skeletal mechanotransduction. J. Biol. Chem. 280, 42952-429599
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 42952-429599
-
-
Li, J.1
Liu, D.2
Ke, H.Z.3
Duncan, R.L.4
Turner, C.H.5
-
63
-
-
0028897128
-
Effect of age on bone density and bone turnover in men
-
Wishart, J. M., Need, A. G., Horowitz, M., Morris, H. A., and Nordin, B. E. (1995) Effect of age on bone density and bone turnover in men. Clin. Endocrinol. (Oxf.) 42, 141-1466
-
(1995)
Clin. Endocrinol. (Oxf.)
, vol.42
, pp. 141-1466
-
-
Wishart, J.M.1
Need, A.G.2
Horowitz, M.3
Morris, H.A.4
Nordin, B.E.5
-
64
-
-
0033014787
-
Age-related changes in bone turnover in men
-
Fatayerji, D., and Eastell, R. (1999) Age-related changes in bone turnover in men. J. Bone Miner. Res. 14, 1203-12100
-
(1999)
J. Bone Miner. Res.
, vol.14
, pp. 1203-12100
-
-
Fatayerji, D.1
Eastell, R.2
-
65
-
-
0031944220
-
Calciotropic hormones and bone markers in the elderly
-
Gallagher, J. C., Kinyamu, H. K., Fowler, S. E., Dawson-Hughes, B., Dalsky, G. P., and Sherman, S. S. (1998) Calciotropic hormones and bone markers in the elderly. J. Bone Miner. Res. 13, 475-4822
-
(1998)
J. Bone Miner. Res.
, vol.13
, pp. 475-4822
-
-
Gallagher, J.C.1
Kinyamu, H.K.2
Fowler, S.E.3
Dawson-Hughes, B.4
Dalsky, G.P.5
Sherman, S.S.6
-
66
-
-
0036517456
-
Predictors of bone mineral density in aging healthy men varies by skeletal site
-
Clarke, B. L., Ebeling, P. R., Jones, J. D., Wahner, H. W., O'Fallon, W. M., Riggs, B. L., and Fitzpatrick, L. A. (2002) Predictors of bone mineral density in aging healthy men varies by skeletal site. Calcif. Tissue Int. 70, 137-1455
-
(2002)
Calcif. Tissue Int.
, vol.70
, pp. 137-1455
-
-
Clarke, B.L.1
Ebeling, P.R.2
Jones, J.D.3
Wahner, H.W.4
O'Fallon, W.M.5
Riggs, B.L.6
Fitzpatrick, L.A.7
|