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Volumn 9, Issue 3, 2014, Pages

Megakaryocytic leukemia 1 (MKL1) regulates hypoxia induced pulmonary hypertension in rats

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; MEGAKARYOCYTIC LEUKEMIA 1; MESSENGER RNA; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CYTOKINE; MYOCARDIN-RELATED TRANSCRIPTION FACTOR-A, RAT; SMALL INTERFERING RNA;

EID: 84898617968     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083895     Document Type: Article
Times cited : (12)

References (44)
  • 1
    • 33749345684 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary vascular remodeling: Cellular and molecular mechanisms
    • DOI 10.1161/01.RES.0000243584.45145.3f, PII 0000301220060929000005
    • Stenmark KR, Fagan KA, Frid MG (2006) Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res 99: 675-691. (Pubitemid 44498302)
    • (2006) Circulation Research , vol.99 , Issue.7 , pp. 675-691
    • Stenmark, K.R.1    Fagan, K.A.2    Frid, M.G.3
  • 2
    • 46749142123 scopus 로고    scopus 로고
    • Molecular pathogenesis of pulmonary arterial hypertension
    • Rabinovitch M (2008) Molecular pathogenesis of pulmonary arterial hypertension. J Clin Invest 118: 2372-2379.
    • (2008) J Clin Invest , vol.118 , pp. 2372-2379
    • Rabinovitch, M.1
  • 3
    • 0345215168 scopus 로고    scopus 로고
    • Inflammatory cytokines in BAL fluid and pulmonary hemodynamics in high-altitude pulmonary edema
    • Kubo K, Hanaoka M, Hayano T, Miyahara T, Hachiya T, et al. (1998) Inflammatory cytokines in BAL fluid and pulmonary hemodynamics in high-altitude pulmonary edema. Respiration Physiology 111: 301-310.
    • (1998) Respiration Physiology , vol.111 , pp. 301-310
    • Kubo, K.1    Hanaoka, M.2    Hayano, T.3    Miyahara, T.4    Hachiya, T.5
  • 6
    • 0027970661 scopus 로고
    • Persistence, re-expression, and induction of pulmonary arterial fibronectin, tropoelastin, and type I procollagen mRNA expression in neonatal hypoxic pulmonary hypertension
    • Durmowicz AG, Parks WC, Hyde DM, Mecham RP, Stenmark KR (1994) Persistence, re-expression, and induction of pulmonary arterial fibronectin, tropoelastin, and type I procollagen mRNA expression in neonatal hypoxic pulmonary hypertension. Am J Pathol 145: 1411-1420. (Pubitemid 24378495)
    • (1994) American Journal of Pathology , vol.145 , Issue.6 , pp. 1411-1420
    • Durmowicz, A.G.1    Parks, W.C.2    Hyde, D.M.3    Mecham, R.P.4    Stenmark, K.R.5
  • 8
    • 0042691723 scopus 로고    scopus 로고
    • Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes
    • DOI 10.1128/MCB.23.18.6597-6608.2003
    • Cen B, Selvaraj A, Burgess RC, Hitzler JK, Ma Z, et al. (2003) Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes. Mol Cell Biol 23: 6597-6608. (Pubitemid 37075770)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.18 , pp. 6597-6608
    • Cen, B.1    Selvaraj, A.2    Burgess, R.C.3    Hitzler, J.K.4    Ma, Z.5    Morris, S.W.6    Prywes, R.7
  • 9
    • 77955173404 scopus 로고    scopus 로고
    • Myocardin-related transcription factor - A controls myofibroblast activation and fibrosis in response to myocardial infarction
    • Small EM, Thatcher JE, Sutherland LB, Kinoshita H, Gerard RD, et al. (2010) Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction. Circ Res 107: 294-304.
    • (2010) Circ Res , vol.107 , pp. 294-304
    • Small, E.M.1    Thatcher, J.E.2    Sutherland, L.B.3    Kinoshita, H.4    Gerard, R.D.5
  • 10
    • 77956629432 scopus 로고    scopus 로고
    • Myocardin-related transcription factor A is a common mediator of mechanical stress- and neurohumoral stimulation-induced cardiac hypertrophic signaling leading to activation of brain natriuretic peptide gene expression
    • Kuwahara K, Kinoshita H, Kuwabara Y, Nakagawa Y, Usami S, et al. (2010) Myocardin-related transcription factor A is a common mediator of mechanical stress- and neurohumoral stimulation-induced cardiac hypertrophic signaling leading to activation of brain natriuretic peptide gene expression. Mol Cell Biol 30: 4134-4148.
    • (2010) Mol Cell Biol , vol.30 , pp. 4134-4148
    • Kuwahara, K.1    Kinoshita, H.2    Kuwabara, Y.3    Nakagawa, Y.4    Usami, S.5
  • 11
    • 79954889437 scopus 로고    scopus 로고
    • Myocardin-related transcription factor A mediates OxLDL-induced endothelial injury
    • Fang F, Yang Y, Yuan Z, Gao Y, Zhou J, et al. (2011) Myocardin-related transcription factor A mediates OxLDL-induced endothelial injury. Circ Res 108: 797-807.
    • (2011) Circ Res , vol.108 , pp. 797-807
    • Fang, F.1    Yang, Y.2    Yuan, Z.3    Gao, Y.4    Zhou, J.5
  • 12
    • 84869209249 scopus 로고    scopus 로고
    • SIRT1 deacetylates RFX5 and antagonizes repression of collagen type I (COL1A2) transcription in smooth muscle cells
    • Xia J, Wu X, Yang Y, Zhao Y, Fang M, et al. (2012) SIRT1 deacetylates RFX5 and antagonizes repression of collagen type I (COL1A2) transcription in smooth muscle cells. Biochem Biophys Res Commun 428: 264-270.
    • (2012) Biochem Biophys Res Commun , vol.428 , pp. 264-270
    • Xia, J.1    Wu, X.2    Yang, Y.3    Zhao, Y.4    Fang, M.5
  • 13
    • 67949121946 scopus 로고    scopus 로고
    • RFXB and its splice variant RFXBSV mediate the antagonism between IFNgamma and TGFbeta on COL1A2 transcription in vascular smooth muscle cells
    • Fang M, Kong X, Li P, Fang F, Wu X, et al. (2009) RFXB and its splice variant RFXBSV mediate the antagonism between IFNgamma and TGFbeta on COL1A2 transcription in vascular smooth muscle cells. Nucleic Acids Res 37: 4393-4406.
    • (2009) Nucleic Acids Res , vol.37 , pp. 4393-4406
    • Fang, M.1    Kong, X.2    Li, P.3    Fang, F.4    Wu, X.5
  • 14
    • 77954601904 scopus 로고    scopus 로고
    • Activation and repression of cellular immediate early genes by serum response factor cofactors
    • Lee SM, Vasishtha M, Prywes R (2010) Activation and repression of cellular immediate early genes by serum response factor cofactors. J Biol Chem 285: 22036-22049.
    • (2010) J Biol Chem , vol.285 , pp. 22036-22049
    • Lee, S.M.1    Vasishtha, M.2    Prywes, R.3
  • 16
    • 14444283145 scopus 로고    scopus 로고
    • The orally active ET(A) receptor antagonist (+)-(S)-2-(4,6-dimethoxy- pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid (LU 135252) prevents the development of pulmonary hypertension and endothelial metabolic dysfunction in monocrotaline-treated rats
    • Prie S, Leung TK, Cernacek P, Ryan JW, Dupuis J (1997) The orally active ET(A) receptor antagonist (+)-(S)-2-(4,6-dimethoxy-pyrimidin-2-yloxy)-3-methoxy- 3,3-diphenyl-propionic acid (LU 135252) prevents the development of pulmonary hypertension and endothelial metabolic dysfunction in monocrotaline-treated rats. J Pharmacol Exp Ther 282: 1312-1318. (Pubitemid 27408309)
    • (1997) Journal of Pharmacology and Experimental Therapeutics , vol.282 , Issue.3 , pp. 1312-1318
    • Prie, S.1    Leung, T.K.2    Cernacek, P.3    Ryan, J.W.4    Dupuis, J.5
  • 17
    • 84898667595 scopus 로고    scopus 로고
    • Brahma related gene 1 (Brg1) bridges epigenetic regulation of pro-inflammatory cytokine production to steatohepatitis
    • Tian W, Xu H, Fang F, Chen Q, Xu Y, et al. (2012) Brahma related gene 1 (Brg1) bridges epigenetic regulation of pro-inflammatory cytokine production to steatohepatitis. Hepatology.
    • (2012) Hepatology
    • Tian, W.1    Xu, H.2    Fang, F.3    Chen, Q.4    Xu, Y.5
  • 18
    • 63349106348 scopus 로고    scopus 로고
    • PPARgamma enhances IFNgamma-mediated transcription and rescues the TGFbeta antagonism by stimulating CIITA in vascular smooth muscle cells
    • Kong X, Fang M, Fang F, Li P, Xu Y (2009) PPARgamma enhances IFNgamma-mediated transcription and rescues the TGFbeta antagonism by stimulating CIITA in vascular smooth muscle cells. J Mol Cell Cardiol 46: 748-757.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 748-757
    • Kong, X.1    Fang, M.2    Fang, F.3    Li, P.4    Xu, Y.5
  • 19
    • 59149095347 scopus 로고    scopus 로고
    • HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells
    • Kong X, Fang M, Li P, Fang F, Xu Y (2009) HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells. J Mol Cell Cardiol 46: 292-299.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 292-299
    • Kong, X.1    Fang, M.2    Li, P.3    Fang, F.4    Xu, Y.5
  • 23
    • 79955772251 scopus 로고    scopus 로고
    • Early macrophage recruitment and alternative activation are critical for the later development of hypoxia-induced pulmonary hypertension
    • Vergadi E, Chang MS, Lee C, Liang OD, Liu X, et al. (2011) Early macrophage recruitment and alternative activation are critical for the later development of hypoxia-induced pulmonary hypertension. Circulation 123: 1986-1995.
    • (2011) Circulation , vol.123 , pp. 1986-1995
    • Vergadi, E.1    Chang, M.S.2    Lee, C.3    Liang, O.D.4    Liu, X.5
  • 25
    • 59849118025 scopus 로고    scopus 로고
    • Interleukin-6 overexpression induces pulmonary hypertension
    • 228p following 244
    • Steiner MK, Syrkina OL, Kolliputi N, Mark EJ, Hales CA, et al. (2009) Interleukin-6 overexpression induces pulmonary hypertension. Circ Res 104: 236-244, 228p following 244.
    • (2009) Circ Res , vol.104 , pp. 236-244
    • Steiner, M.K.1    Syrkina, O.L.2    Kolliputi, N.3    Mark, E.J.4    Hales, C.A.5
  • 26
    • 0028598729 scopus 로고
    • TNF potentiates PAF-induced pulmonary vasoconstriction in the rat: Role of neutrophils and thromboxane A2
    • Chang SW (1994) TNF potentiates PAF-induced pulmonary vasoconstriction in the rat: role of neutrophils and thromboxane A2. J Appl Physiol 77: 2817-2826.
    • (1994) J Appl Physiol , vol.77 , pp. 2817-2826
    • Chang, S.W.1
  • 28
    • 0026576318 scopus 로고
    • Liposome-entrapped antifibrotic agent prevents collagen accumulation in hypertensive pulmonary arteries of rats
    • Poiani GJ, Wilson FJ, Fox JD, Sumka JM, Peng BW, et al. (1992) Liposome-entrapped antifibrotic agent prevents collagen accumulation in hypertensive pulmonary arteries of rats. Circ Res 70: 912-922.
    • (1992) Circ Res , vol.70 , pp. 912-922
    • Poiani, G.J.1    Wilson, F.J.2    Fox, J.D.3    Sumka, J.M.4    Peng, B.W.5
  • 29
    • 77952234421 scopus 로고    scopus 로고
    • Basic science of pulmonary arterial hypertension for clinicians: New concepts and experimental therapies
    • Archer SL, Weir EK, Wilkins MR (2010) Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies. Circulation 121: 2045-2066.
    • (2010) Circulation , vol.121 , pp. 2045-2066
    • Archer, S.L.1    Weir, E.K.2    Wilkins, M.R.3
  • 30
    • 70049098149 scopus 로고    scopus 로고
    • Role for interleukin-6 in COPD-related pulmonary hypertension
    • Chaouat A, Savale L, Chouaid C, Tu L, Sztrymf B, et al. (2009) Role for interleukin-6 in COPD-related pulmonary hypertension. Chest 136: 678-687.
    • (2009) Chest , vol.136 , pp. 678-687
    • Chaouat, A.1    Savale, L.2    Chouaid, C.3    Tu, L.4    Sztrymf, B.5
  • 31
    • 80052667354 scopus 로고    scopus 로고
    • Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension
    • Li M, Riddle SR, Frid MG, El Kasmi KC, McKinsey TA, et al. (2011) Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension. J Immunol 187: 2711-2722.
    • (2011) J Immunol , vol.187 , pp. 2711-2722
    • Li, M.1    Riddle, S.R.2    Frid, M.G.3    El Kasmi, K.C.4    McKinsey, T.A.5
  • 32
    • 80051987703 scopus 로고    scopus 로고
    • Crosstalk in NF-kappaB signaling pathways
    • Oeckinghaus A, Hayden MS, Ghosh S (2011) Crosstalk in NF-kappaB signaling pathways. Nat Immunol 12: 695-708.
    • (2011) Nat Immunol , vol.12 , pp. 695-708
    • Oeckinghaus, A.1    Hayden, M.S.2    Ghosh, S.3
  • 33
    • 27444448072 scopus 로고    scopus 로고
    • Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome
    • DOI 10.1161/CIRCULATIONAHA.105.556746
    • Ryan S, Taylor CT, McNicholas WT (2005) Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation 112: 2660-2667. (Pubitemid 41532603)
    • (2005) Circulation , vol.112 , Issue.17 , pp. 2660-2667
    • Ryan, S.1    Taylor, C.T.2    McNicholas, W.T.3
  • 34
    • 33645730645 scopus 로고    scopus 로고
    • The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: Role in redox-sensitive regulation of tissue factor by thrombin
    • BelAiba RS, Djordjevic T, Bonello S, Artunc F, Lang F, et al. (2006) The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: role in redox-sensitive regulation of tissue factor by thrombin. Circ Res 98: 828-836.
    • (2006) Circ Res , vol.98 , pp. 828-836
    • BelAiba, R.S.1    Djordjevic, T.2    Bonello, S.3    Artunc, F.4    Lang, F.5
  • 36
    • 0026052725 scopus 로고
    • Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 59-regulatory region. Induction by cytokines and phorbol ester
    • Voraberger G, Schafer R, Stratowa C (1991) Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 59-regulatory region. Induction by cytokines and phorbol ester. J Immunol 147: 2777-2786.
    • (1991) J Immunol , vol.147 , pp. 2777-2786
    • Voraberger, G.1    Schafer, R.2    Stratowa, C.3
  • 37
    • 0025896795 scopus 로고
    • Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis
    • Cybulsky MI, Gimbrone MA, Jr. (1991) Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 251: 788-791.
    • (1991) Science , vol.251 , pp. 788-791
    • Cybulsky, M.I.1    Gimbrone Jr., M.A.2
  • 40
    • 83755162557 scopus 로고    scopus 로고
    • Myocardin Related Transcription Factor-A Complexes Activate Type I Collagen Expression in Lung Fibroblasts
    • Luchsinger LL, Patenaude CA, Smith BD, Layne MD (2011) Myocardin Related Transcription Factor-A Complexes Activate Type I Collagen Expression in Lung Fibroblasts. J Biol Chem.
    • (2011) J Biol Chem
    • Luchsinger, L.L.1    Patenaude, C.A.2    Smith, B.D.3    Layne, M.D.4
  • 41
    • 59649110562 scopus 로고    scopus 로고
    • SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells
    • Bell RD, Deane R, Chow N, Long X, Sagare A, et al. (2009) SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells. Nat Cell Biol 11: 143-153.
    • (2009) Nat Cell Biol , vol.11 , pp. 143-153
    • Bell, R.D.1    Deane, R.2    Chow, N.3    Long, X.4    Sagare, A.5
  • 42
    • 84870389718 scopus 로고    scopus 로고
    • Transcriptional regulation of specific protein 1 (SP1) by hypoxia-inducible factor 1 alpha (HIF-1alpha) leads to PRNP expression and neuroprotection from toxic prion peptide
    • Jeong JK, Park SY (2012) Transcriptional regulation of specific protein 1 (SP1) by hypoxia-inducible factor 1 alpha (HIF-1alpha) leads to PRNP expression and neuroprotection from toxic prion peptide. Biochem Biophys Res Commun 429: 93-98.
    • (2012) Biochem Biophys Res Commun , vol.429 , pp. 93-98
    • Jeong, J.K.1    Park, S.Y.2
  • 43
    • 84863223765 scopus 로고    scopus 로고
    • HIF2alpha-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells
    • Koizume S, Ito S, Miyagi E, Hirahara F, Nakamura Y, et al. (2012) HIF2alpha-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells. Nucleic Acids Res 40: 5389-5401.
    • (2012) Nucleic Acids Res , vol.40 , pp. 5389-5401
    • Koizume, S.1    Ito, S.2    Miyagi, E.3    Hirahara, F.4    Nakamura, Y.5
  • 44
    • 84865853068 scopus 로고    scopus 로고
    • Myocardin-like protein 2 regulates TGFbeta signaling in embryonic stem cells and the developing vasculature
    • Li J, Bowens N, Cheng L, Zhu X, Chen M, et al. (2012) Myocardin-like protein 2 regulates TGFbeta signaling in embryonic stem cells and the developing vasculature. Development 139: 3531-3542.
    • (2012) Development , vol.139 , pp. 3531-3542
    • Li, J.1    Bowens, N.2    Cheng, L.3    Zhu, X.4    Chen, M.5


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