Lyn kinase plays important roles in erythroid expansion, maturation and erythropoietin receptor signalling by regulating inhibitory signalling pathways that control survival

Biochemical Journal

Volumn 459, Issue 3, 2014, Pages 455-466

  Slavova Azmanova, Neli S ^a   Kucera, Nicole ^a   Louw, Alison ^a,b   Satiaputra, Jiulia ^a   Handoko, Adley ^a   Singer, Peter ^a   Stone, Leah ^a,b   McCarthy, David J ^a   Klinken, S Peter ^a   Hibbs, Margaret L ^c   Ingley, Evan ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b ROYAL PERTH HOSPITAL   (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Akt; Erythropoiesis; Erythropoietin; Ex vivo; Lyn; Src homology 2 domain containing protein tyrosine phosphatase 1 (SHP 1)

Indexed keywords

ERYTHROPOIETIN RECEPTOR; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE LYN; PROTEIN TYROSINE PHOSPHATASE SHP; STAT5 PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL EXPANSION; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CLONOGENESIS; CONTROLLED STUDY; ERYTHROBLAST; ERYTHROCYTE CULTURE; ERYTHROID CELL; ERYTHROID PRECURSOR CELL; ERYTHROPOIESIS; EX VIVO STUDY; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CELL DIFFERENTIATION; CELL LINE, TRANSFORMED; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; EMBRYO, MAMMALIAN; ERYTHROBLASTS; ERYTHROID PRECURSOR CELLS; ERYTHROPOIESIS; ERYTHROPOIETIN; HEMATINICS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PROTEIN KINASE INHIBITORS; PYRIMIDINES; RECEPTORS, ERYTHROPOIETIN; SIGNAL TRANSDUCTION; SPLEEN; SRC-FAMILY KINASES;

EID: 84898612227     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130903     Document Type: Article

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