Deficiency of SHP1 leads to sustained and increased ERK activation in mast cells, thereby inhibiting IL-3-dependent proliferation and cell death

Molecular Immunology

Volumn 48, Issue 4, 2011, Pages 472-480

  Nakata, Kazuko ^a   Suzuki, Yoshihiro ^b   Inoue, Toshio ^b   Ra, Chisei ^b   Yakura, Hidetaka ^a   Mizuno, Kazuya ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b NIHON UNIVERSITY   (Japan)

Author keywords

Apoptosis; Cell proliferation; ERK; IL 3; Mast cells; SHP 1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; INTERLEUKIN 3; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

ANIMALS; BIOCATALYSIS; BONE MARROW CELLS; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; INTERLEUKIN-3; MAST CELLS; MICE; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6;

MUS;

EID: 78650592361     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.10.001     Document Type: Article

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