메뉴 건너뛰기




Volumn 28, Issue 4, 2014, Pages 749-760

Induced differentiation of acute myeloid leukemia cells by activation of retinoid X and liver X receptors

Author keywords

acute myeloid leukemia; liver X receptors; myeloid differentiation; retinoid X receptors; rexinoids

Indexed keywords

3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; BEXAROTENE; LIVER X RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; RETINOIC ACID; RETINOID X RECEPTOR; ROSIGLITAZONE; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR PU 1;

EID: 84898484716     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2013.202     Document Type: Article
Times cited : (31)

References (42)
  • 1
    • 79958002038 scopus 로고    scopus 로고
    • Revisiting the differentiation paradigm in acute promyelocytic leukemia
    • Ablain J, de The H. Revisiting the differentiation paradigm in acute promyelocytic leukemia. Blood 2011; 117: 5795-5802.
    • (2011) Blood , vol.117 , pp. 5795-5802
    • Ablain, J.1    De The, H.2
  • 2
    • 0025981102 scopus 로고
    • Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor {alpha} locus
    • Alcalay M, Zangrilli D, Pandolfi PP, Longo L, Mencarelli A, angelo G et al. Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor {alpha} locus. Proc Natl Acad Sci USA 1991; 88: 1977-1981.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 1977-1981
    • Alcalay, M.1    Zangrilli, D.2    Pandolfi, P.P.3    Longo, L.4    Mencarelli, A.5    Angelo, G.6
  • 3
    • 79955767844 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation rates and long-term survival in acute myeloid and lymphoblastic leukemia: Real-world population-based data from the Swedish Acute Leukemia Registry 1997-2006
    • Juliusson G, Karlsson K, Lazarevic V, Wahlin A, Brune M, Antunovic P et al. Hematopoietic stem cell transplantation rates and long-term survival in acute myeloid and lymphoblastic leukemia: real-world population-based data from the Swedish Acute Leukemia Registry 1997-2006. Cancer 2011; 117: 4238-4246.
    • (2011) Cancer , vol.117 , pp. 4238-4246
    • Juliusson, G.1    Karlsson, K.2    Lazarevic, V.3    Wahlin, A.4    Brune, M.5    Antunovic, P.6
  • 4
    • 53049109215 scopus 로고    scopus 로고
    • A phase i study of bexarotene, a retinoic X receptor agonist, in non-M3 acute myeloid leukemia
    • Tsai DE, Luger SM, Andreadis C, Vogl DT, Kemner A, Potuzak M et al. A phase I study of bexarotene, a retinoic X receptor agonist, in non-M3 acute myeloid leukemia. Clin Cancer Res 2008; 14: 5619-5625.
    • (2008) Clin Cancer Res , vol.14 , pp. 5619-5625
    • Tsai, D.E.1    Luger, S.M.2    Andreadis, C.3    Vogl, D.T.4    Kemner, A.5    Potuzak, M.6
  • 5
    • 0034957480 scopus 로고    scopus 로고
    • Nuclear hormone receptors and gene expression
    • Aranda A, Pascual A. Nuclear hormone receptors and gene expression. Physiol Rev 2001; 81: 1269-1304. (Pubitemid 32606670)
    • (2001) Physiological Reviews , vol.81 , Issue.3 , pp. 1269-1304
    • Aranda, A.1    Pascual, A.2
  • 8
    • 33645734361 scopus 로고    scopus 로고
    • ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression
    • Mueller BU, Pabst T, Fos J, Petkovic V, Fey MF, Asou N et al. ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression. Blood 2006; 107: 3330-3338.
    • (2006) Blood , vol.107 , pp. 3330-3338
    • Mueller, B.U.1    Pabst, T.2    Fos, J.3    Petkovic, V.4    Fey, M.F.5    Asou, N.6
  • 10
    • 0037222293 scopus 로고    scopus 로고
    • The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia
    • DOI 10.1182/blood-2002-04-1288
    • Vangala RK, Heiss-Neumann MS, Rangatia JS, Singh SM, Schoch C, Tenen DG et al. The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia. Blood 2003; 101: 270-277. (Pubitemid 36025918)
    • (2003) Blood , vol.101 , Issue.1 , pp. 270-277
    • Vangala, R.K.1    Heiss-Neumann, M.S.2    Rangatia, J.S.3    Singh, S.M.4    Schoch, C.5    Tenen, D.G.6    Hiddemann, W.7    Behre, G.8
  • 12
    • 0142124320 scopus 로고    scopus 로고
    • Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPα ratio and granulocyte colony-stimulating factor
    • DOI 10.1038/ni973
    • Dahl R, Walsh JC, Lancki D, Laslo P, Iyer SR, Singh H et al. Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor. Nat Immunol 2003; 4: 1029-1036. (Pubitemid 37265925)
    • (2003) Nature Immunology , vol.4 , Issue.10 , pp. 1029-1036
    • Dahl, R.1    Walsh, J.C.2    Lancki, D.3    Laslo, P.4    Iyer, S.R.5    Singh, H.6    Celeste Simon, M.7
  • 14
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods (San Diego, CA) 2001; 25: 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 15
    • 2942579791 scopus 로고    scopus 로고
    • Retinoic acid regulates cell cycle progression and cell differentiation in human monocytic THP-1 cells
    • DOI 10.1016/j.yexcr.2004.02.017, PII S001448270400103X
    • Chen Q, Ross AC. Retinoic acid regulates cell cycle progression and cell differentiation in human monocytic THP-1 cells. Exp Cell Res 2004; 297: 68-81. (Pubitemid 38759563)
    • (2004) Experimental Cell Research , vol.297 , Issue.1 , pp. 68-81
    • Chen, Q.1    Ross, A.C.2
  • 16
    • 1842555105 scopus 로고    scopus 로고
    • Granulocytic differentiation of leukemic cells with t(9;11)(p22;q23) induced by all-trans-retinoic acid
    • DOI 10.1080/1042819031000163887
    • Iijima K, Honma Y, Niitsu N. Granulocytic differentiation of leukemic cells with t(9;11)(p22;q23) induced by all-trans-retinoic acid. Leuk Lymphoma 2004; 45: 1017-1024. (Pubitemid 38444679)
    • (2004) Leukemia and Lymphoma , vol.45 , Issue.5 , pp. 1017-1024
    • Iijima, K.1    Honma, Y.2    Niitsu, N.3
  • 18
    • 0034955152 scopus 로고    scopus 로고
    • Bexarotene metabolism in rat, dog, and human, synthesis of oxidative metabolites, and in vitro activity at retinoid receptors
    • Howell SR, Shirley MA, Grese TA, Neel DA, Wells KE, Ulm EH. Bexarotene metabolism in rat, dog, and human, synthesis of oxidative metabolites, and in vitro activity at retinoid receptors. Drug Metab Dispos 2001; 29: 990-998. (Pubitemid 32605914)
    • (2001) Drug Metabolism and Disposition , vol.29 , Issue.7 , pp. 990-998
    • Howell, S.R.1    Shirley, M.A.2    Grese, T.A.3    Neel, D.A.4    Wells, K.E.5    Ulm, E.H.6
  • 20
    • 0033559654 scopus 로고    scopus 로고
    • Effects of novel RAR- and RXR-selective retinoids on myeloid leukemic proliferation and differentiation in vitro
    • Shiohara M, Dawson MI, Hobbs PD, Sawai N, Higuchi T, Koike K et al. Effects of novel RAR-and RXR-selective retinoids on myeloid leukemic proliferation and differentiation in vitro. Blood 1999; 93: 2057-2066. (Pubitemid 29128509)
    • (1999) Blood , vol.93 , Issue.6 , pp. 2057-2066
    • Shiohara, M.1    Dawson, M.I.2    Hobbs, P.D.3    Sawai, N.4    Higuchi, T.5    Koike, K.6    Komiyama, A.7    Koeffler, H.P.8
  • 24
    • 0035102650 scopus 로고    scopus 로고
    • The role of C/EBPε in the terminal stages of granulocyte differentiation
    • Lekstrom-Himes JA. The role of C/EBP(epsilon) in the terminal stages of granulocyte differentiation. Stem cells (Dayton, OH) 2001; 19: 125-133. (Pubitemid 32222237)
    • (2001) Stem Cells , vol.19 , Issue.2 , pp. 125-133
    • Lekstrom-Himes, J.A.1
  • 25
    • 35348875999 scopus 로고    scopus 로고
    • Transcriptional control of granulocyte and monocyte development
    • DOI 10.1038/sj.onc.1210764, PII 1210764
    • Friedman AD. Transcriptional control of granulocyte and monocyte development. Oncogene 2007; 26: 6816-6828. (Pubitemid 47585105)
    • (2007) Oncogene , vol.26 , Issue.47 , pp. 6816-6828
    • Friedman, A.D.1
  • 27
    • 83755205792 scopus 로고    scopus 로고
    • Regulatory gene network circuits underlying T cell development from multipotent progenitors
    • Kueh HY, Rothenberg EV. Regulatory gene network circuits underlying T cell development from multipotent progenitors. Wiley Interdiscip Rev Syst Biol Med 2011; 4: 79-102.
    • (2011) Wiley Interdiscip Rev Syst Biol Med , vol.4 , pp. 79-102
    • Kueh, H.Y.1    Rothenberg, E.V.2
  • 28
    • 78651486442 scopus 로고    scopus 로고
    • Densely interconnected transcriptional circuits control cell states in human hematopoiesis
    • Novershtern N, Subramanian A, Lawton LN, Mak RH, Haining WN, McConkey ME et al. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell 2011; 144: 296-309.
    • (2011) Cell , vol.144 , pp. 296-309
    • Novershtern, N.1    Subramanian, A.2    Lawton, L.N.3    Mak, R.H.4    Haining, W.N.5    McConkey, M.E.6
  • 30
    • 17344380620 scopus 로고    scopus 로고
    • Genomic structure and mapping of human orphan receptor LXR alpha: Upregulation of LXRa mRNA during monocyte to macrophage differentiation
    • Kohro T, Nakajima T, Wada Y, Sugiyama A, Ishii M, Tsutsumi S et al. Genomic structure and mapping of human orphan receptor LXR alpha: upregulation of LXRa mRNA during monocyte to macrophage differentiation. J Atheroscl Thromb 2000; 7: 145-151.
    • (2000) J Atheroscl Thromb , vol.7 , pp. 145-151
    • Kohro, T.1    Nakajima, T.2    Wada, Y.3    Sugiyama, A.4    Ishii, M.5    Tsutsumi, S.6
  • 31
    • 33646486572 scopus 로고    scopus 로고
    • Selective expression of cholesterol metabolism genes in normal CD34\+CD38-cells with a heterogeneous expression pattern in AML cells
    • Peeters SD, van der Kolk DM, de Haan G, Bystrykh L, Kuipers F, de Vries EG et al. Selective expression of cholesterol metabolism genes in normal CD34\+CD38-cells with a heterogeneous expression pattern in AML cells. Exp Hemat 2006; 34: 622-630.
    • (2006) Exp Hemat , vol.34 , pp. 622-630
    • Peeters, S.D.1    Van Der Kolk, D.M.2    De Haan, G.3    Bystrykh, L.4    Kuipers, F.5    De Vries, E.G.6
  • 32
    • 74549224652 scopus 로고    scopus 로고
    • The benzenesulfoamide T0901317 [N-(2 2,2-trifluoroethyl)-N-[4-[2,2,2- trifluoro-1-hydroxy-1-(trifluorometh yl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist
    • Kumar N, Solt LA, Conkright JJ, Wang Y, Istrate MA, Busby SA et al. The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1- hydroxy-1-(trifluorometh yl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist. Mol Pharmacol 2010; 77: 228-236.
    • (2010) Mol Pharmacol , vol.77 , pp. 228-236
    • Kumar, N.1    Solt, L.A.2    Conkright, J.J.3    Wang, Y.4    Istrate, M.A.5    Busby, S.A.6
  • 33
    • 79955526989 scopus 로고    scopus 로고
    • Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand
    • Solt LA, Kumar N, Nuhant P, Wang Y, Lauer JL, Liu J et al. Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand. Nature 2011; 472: 491-494.
    • (2011) Nature , vol.472 , pp. 491-494
    • Solt, L.A.1    Kumar, N.2    Nuhant, P.3    Wang, Y.4    Lauer, J.L.5    Liu, J.6
  • 34
    • 0036796916 scopus 로고    scopus 로고
    • The role of retinoids and retinoic acid receptors in normal hematopoiesis
    • DOI 10.1038/sj.leu.2402718
    • Collins SJ. The role of retinoids and retinoic acid receptors in normal hematopoiesis. Leukemia 2002; 16: 1896-1905. (Pubitemid 35203432)
    • (2002) Leukemia , vol.16 , Issue.10 , pp. 1896-1905
    • Collins, S.J.1
  • 35
    • 0036796742 scopus 로고    scopus 로고
    • Retinoic acid resistance in acute promyelocytic leukemia
    • DOI 10.1038/sj.leu.2402719
    • Gallagher RE. Retinoic acid resistance in acute promyelocytic leukemia. Leukemia 2002; 16: 1940-1958. (Pubitemid 35203437)
    • (2002) Leukemia , vol.16 , Issue.10 , pp. 1940-1958
    • Gallagher, R.E.1
  • 36
    • 0035283124 scopus 로고    scopus 로고
    • Positive and negative regulation of granulopoiesis by endogenous RARα
    • DOI 10.1182/blood.V97.5.1314
    • Kastner P, Lawrence HJ, Waltzinger C, Ghyselinck NB, Chambon P, Chan S. Positive and negative regulation of granulopoiesis by endogenous RARalpha. Blood 2001; 97: 1314-1320. (Pubitemid 32183754)
    • (2001) Blood , vol.97 , Issue.5 , pp. 1314-1320
    • Kastner, P.1    Lawrence, H.J.2    Waltzinger, C.3    Ghyselinck, N.B.4    Chambon, P.5    Chan, S.6
  • 37
    • 33751531527 scopus 로고    scopus 로고
    • Normal hematopoiesis after conditional targeting of RXRα in murine hematopoietic stem/progenitor cells
    • DOI 10.1189/jlb.0206097
    • Ricote M, Snyder CS, Leung HY, Chen J, Chien KR, Glass CK. Normal hematopoiesis after conditional targeting of RXRalpha in murine hematopoietic stem/progenitor cells. J Leuk Biol 2006; 80: 850-861. (Pubitemid 44835903)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.4 , pp. 850-861
    • Ricote, M.1    Snyder, C.S.2    Leung, H.-Y.3    Chen, J.4    Chien, K.R.5    Glass, C.K.6
  • 38
    • 34247631683 scopus 로고    scopus 로고
    • Lentiviral PU.1 overexpression restores differentiation in myeloid leukemic blasts
    • DOI 10.1038/sj.leu.2404645, PII 2404645
    • Durual S, Rideau A, Ruault-Jungblut S, Cossali D, Beris P, Piguet V et al. Lentiviral PU.1 overexpression restores differentiation in myeloid leukemic blasts. Leukemia 2007; 21: 1050-1059. (Pubitemid 46672082)
    • (2007) Leukemia , vol.21 , Issue.5 , pp. 1050-1059
    • Durual, S.1    Rideau, A.2    Ruault-Jungblut, S.3    Cossali, D.4    Beris, P.5    Piguet, V.6    Matthes, T.7
  • 39
    • 21744458442 scopus 로고    scopus 로고
    • Retinoids potentiate peroxisome proliferator-activated receptor γ action in differentiation, gene expression, and lipid metabolic processes in developing myeloid cells
    • DOI 10.1124/mol.104.006445
    • Szanto A, Nagy L. Retinoids potentiate peroxisome proliferator-activated receptor gamma action in differentiation, gene expression, and lipid metabolic processes in developing myeloid cells. Mol Pharmacol 2005; 67: 1935-1943. (Pubitemid 41007775)
    • (2005) Molecular Pharmacology , vol.67 , Issue.6 , pp. 1935-1943
    • Szanto, A.1    Nagy, L.2
  • 40
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
    • DOI 10.1016/S0092-8674(00)81574-3
    • Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 1998; 93: 229-240. (Pubitemid 28180856)
    • (1998) Cell , vol.93 , Issue.2 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.A.3    Chen, H.4    Evans, R.M.5
  • 41
    • 0032540012 scopus 로고    scopus 로고
    • PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • DOI 10.1016/S0092-8674(00)81575-5
    • Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 1998; 93: 241-252. (Pubitemid 28180857)
    • (1998) Cell , vol.93 , Issue.2 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.A.3    Thomazy, V.A.4    Evans, R.M.5
  • 42
    • 77954039619 scopus 로고    scopus 로고
    • ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation
    • Yvan-Charvet L, Pagler T, Gautier EL, Avagyan S, Siry RL, Han S et al. ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. Science 2010; 328: 1689-1693.
    • (2010) Science , vol.328 , pp. 1689-1693
    • Yvan-Charvet, L.1    Pagler, T.2    Gautier, E.L.3    Avagyan, S.4    Siry, R.L.5    Han, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.