In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes

eLife

Volumn 2014, Issue 3, 2014, Pages

  Li, Weida ^a   Nakanishi, Mio ^a,b   Zumsteg, Adrian ^a   Shear, Matthew ^a   Wright, Christopher ^c   Melton, Douglas A ^a   Zhou, Qiao ^a  

^a Harvard University   (United States)

^b MCMASTER UNIVERSITY   (Canada)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLASE; GLUCAGON; INSULIN; NEUROGENIN 3; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HOMEODOMAIN PROTEIN; NERVE PROTEIN; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; PHOTOPROTEIN; RAG-1 PROTEIN; RED FLUORESCENT PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR MAF;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CPG ISLAND; DIABETES MELLITUS; DNA METHYLATION; DOWN REGULATION; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION PROFILING; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MIXED INFECTION; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; NUCLEOTIDE SEQUENCE; OLIGODENDROGLIA; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PERIPHERAL BLOOD STEM CELL; PRE B LYMPHOCYTE; RADIOIMMUNOASSAY; SKIN FIBROBLAST; SOMATOSTATIN CELL; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL LINEAGE; CELL TRANSDIFFERENTIATION; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; HUMAN; KNOCKOUT MOUSE; METABOLISM; PANCREAS; PHYSIOLOGY; REPORTER GENE; TIME;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINEAGE; CELL TRANSDIFFERENTIATION; CELLULAR REPROGRAMMING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; GLUCAGON-SECRETING CELLS; HEK293 CELLS; HOMEODOMAIN PROTEINS; HUMANS; INSULIN-SECRETING CELLS; LUMINESCENT PROTEINS; MAF TRANSCRIPTION FACTORS, LARGE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; PANCREAS, EXOCRINE; SOMATOSTATIN-SECRETING CELLS; TIME FACTORS; TRANS-ACTIVATORS; TRANSFECTION;

EID: 84898477228     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.01846     Document Type: Article

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