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Volumn 289, Issue 14, 2014, Pages 10115-10125

A novel mechanism by which tissue transglutaminase activates signaling events that promote cell survival

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL CULTURE; CELL DEATH; CHEMICAL ACTIVATION; DISEASES; ENZYMES; FIBROBLASTS; PROTEINS;

EID: 84898071562     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.464693     Document Type: Article
Times cited : (36)

References (40)
  • 1
    • 0028828698 scopus 로고
    • Identification and biochemical characterization of an 80 kilodalton GTP-binding/transglu-taminase from rabbit liver nuclei
    • Singh, U. S., Erickson, J. W., and Cerione, R. A. (1995) Identification and biochemical characterization of an 80 kilodalton GTP-binding/transglu- taminase from rabbit liver nuclei. Biochemistry 34, 15863-15871
    • (1995) Biochemistry , vol.34 , pp. 15863-15871
    • Singh, U.S.1    Erickson, J.W.2    Cerione, R.A.3
  • 2
    • 0028176166 scopus 로고
    • Gh: A GTP-binding protein with trans-glutaminase activity and receptor signaling function
    • Nakaoka, H., Perez, D. M., Baek, K. J., Das, T., Husain, A., Misono, K., Im, M. J., and Graham, R. M. (1994) Gh: a GTP-binding protein with trans-glutaminase activity and receptor signaling function. Science 264, 1593-1596
    • (1994) Science , vol.264 , pp. 1593-1596
    • Nakaoka, H.1    Perez, D.M.2    Baek, K.J.3    Das, T.4    Husain, A.5    Misono, K.6    Im, M.J.7    Graham, R.M.8
  • 3
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • Jaffe, A. B., and Hall, A. (2005) Rho GTPases: biochemistry and biology. Annu. Rev. Cell Dev. Biol. 21, 247-269
    • (2005) Annu. Rev. Cell Dev. Biol. , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 4
    • 0018816617 scopus 로고
    • Transglutaminases
    • Folk, J. E. (1980) Transglutaminases. Annu. Rev. Biochem. 49, 517-531
    • (1980) Annu. Rev. Biochem. , vol.49 , pp. 517-531
    • Folk, J.E.1
  • 5
    • 0026338017 scopus 로고
    • Transglutami-nases: Multifunctional cross-linking enzymes that stabilize tissues
    • Greenberg, C. S., Birckbichler, P. J., and Rice, R. H. (1991) Transglutami-nases: multifunctional cross-linking enzymes that stabilize tissues. Faseb J 5, 3071-3077
    • (1991) Faseb J , vol.5 , pp. 3071-3077
    • Greenberg, C.S.1    Birckbichler, P.J.2    Rice, R.H.3
  • 6
    • 0035823548 scopus 로고    scopus 로고
    • Effects of tissue transglutami-nase on retinoic acid-induced cellular differentiation and protection against apoptosis
    • Antonyak, M. A., Singh, U. S., Lee, D. A., Boehm, J. E., Combs, C., Zgola, M. M., Page, R. L., and Cerione, R. A. (2001) Effects of tissue transglutami-nase on retinoic acid-induced cellular differentiation and protection against apoptosis. J. Biol. Chem. 276, 33582-33587
    • (2001) J. Biol. Chem. , vol.276 , pp. 33582-33587
    • Antonyak, M.A.1    Singh, U.S.2    Lee, D.A.3    Boehm, J.E.4    Combs, C.5    Zgola, M.M.6    Page, R.L.7    Cerione, R.A.8
  • 7
    • 0027516486 scopus 로고
    • Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes
    • Aeschlimann, D., Wetterwald, A., Fleisch, H., and Paulsson, M. (1993) Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes. J. Cell Biol. 120, 1461-1470
    • (1993) J. Cell Biol. , vol.120 , pp. 1461-1470
    • Aeschlimann, D.1    Wetterwald, A.2    Fleisch, H.3    Paulsson, M.4
  • 8
    • 0022551074 scopus 로고
    • Expression of tissue transglu-taminase in cultured monocytic leukemia (THP-1) cells during differentiation
    • Mehta, K., and Lopez-Berestein, G. (1986) Expression of tissue transglu-taminase in cultured monocytic leukemia (THP-1) cells during differentiation. Cancer Res. 46, 1388-1394
    • (1986) Cancer Res. , vol.46 , pp. 1388-1394
    • Mehta, K.1    Lopez-Berestein, G.2
  • 9
    • 32944463725 scopus 로고    scopus 로고
    • Tissue transglutaminase (TG2)-a wound response enzyme
    • Telci, D., and Griffin, M. (2006) Tissue transglutaminase (TG2)-a wound response enzyme. Front Biosci. 11, 867-882
    • (2006) Front Biosci. , vol.11 , pp. 867-882
    • Telci, D.1    Griffin, M.2
  • 10
    • 4143089161 scopus 로고    scopus 로고
    • Tissue transglutami-nase in normal and abnormal wound healing: Review article
    • Verderio, E. A., Johnson, T., and Griffin, M. (2004) Tissue transglutami-nase in normal and abnormal wound healing: review article. Amino Acids 26, 387-404
    • (2004) Amino Acids , vol.26 , pp. 387-404
    • Verderio, E.A.1    Johnson, T.2    Griffin, M.3
  • 11
    • 34247349128 scopus 로고    scopus 로고
    • Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy
    • Yuan, L., Siegel, M., Choi, K., Khosla, C., Miller, C. R., Jackson, E. N., Piwnica-Worms, D., and Rich, K. M. (2007) Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy. Oncogene 26, 2563-2573
    • (2007) Oncogene , vol.26 , pp. 2563-2573
    • Yuan, L.1    Siegel, M.2    Choi, K.3    Khosla, C.4    Miller, C.R.5    Jackson, E.N.6    Piwnica-Worms, D.7    Rich, K.M.8
  • 12
    • 33845307265 scopus 로고    scopus 로고
    • Reversal of drug resistance in breast cancer cells by transglutaminase 2 inhibition and nuclear factor-kappaB inactivation
    • Kim, D. S., Park, S. S., Nam, B. H., Kim, I.H., and Kim, S. Y. (2006) Reversal of drug resistance in breast cancer cells by transglutaminase 2 inhibition and nuclear factor-kappaB inactivation. Cancer Res. 66, 10936-10943
    • (2006) Cancer Res. , vol.66 , pp. 10936-10943
    • Kim, D.S.1    Park, S.S.2    Nam, B.H.3    Kim, I.H.4    Kim, S.Y.5
  • 14
    • 33751285778 scopus 로고    scopus 로고
    • Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis
    • Verma, A., Wang, H., Manavathi, B., Fok, J.Y., Mann, A. P., Kumar, R., and Mehta, K. (2006) Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis. Cancer Res. 66, 10525-10533
    • (2006) Cancer Res. , vol.66 , pp. 10525-10533
    • Verma, A.1    Wang, H.2    Manavathi, B.3    Fok, J.Y.4    Mann, A.P.5    Kumar, R.6    Mehta, K.7
  • 16
    • 34247153086 scopus 로고    scopus 로고
    • Tissue transglutaminase expression promotes cell attachment, invasion and survival in breast cancer cells
    • Mangala, L. S., Fok, J. Y., Zorrilla-Calancha, I. R., Verma, A., and Mehta, K. (2007) Tissue transglutaminase expression promotes cell attachment, invasion and survival in breast cancer cells. Oncogene 26, 2459-2470
    • (2007) Oncogene , vol.26 , pp. 2459-2470
    • Mangala, L.S.1    Fok, J.Y.2    Zorrilla-Calancha, I.R.3    Verma, A.4    Mehta, K.5
  • 17
    • 67650538098 scopus 로고    scopus 로고
    • Tissue transglutaminase is an essential participant in the epidermal growth factor-stimulated signaling pathway leading to cancer cell migration and invasion
    • Antonyak, M. A., Li, B., Regan, A. D., Feng, Q., Dusaban, S. S., and Cerione, R. A. (2009) Tissue transglutaminase is an essential participant in the epidermal growth factor-stimulated signaling pathway leading to cancer cell migration and invasion. J. Biol. Chem. 284, 17914-17925
    • (2009) J. Biol. Chem. , vol.284 , pp. 17914-17925
    • Antonyak, M.A.1    Li, B.2    Regan, A.D.3    Feng, Q.4    Dusaban, S.S.5    Cerione, R.A.6
  • 18
    • 33748988771 scopus 로고    scopus 로고
    • Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: Delineation of a novel pathway
    • Mann, A. P., Verma, A., Sethi, G., Manavathi, B., Wang, H., Fok, J. Y., Kunnumakkara, A. B., Kumar, R., Aggarwal, B. B., and Mehta, K. (2006) Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathway. Cancer Res. 66, 8788-8795
    • (2006) Cancer Res. , vol.66 , pp. 8788-8795
    • Mann, A.P.1    Verma, A.2    Sethi, G.3    Manavathi, B.4    Wang, H.5    Fok, J.Y.6    Kunnumakkara, A.B.7    Kumar, R.8    Aggarwal, B.B.9    Mehta, K.10
  • 19
    • 0038326942 scopus 로고    scopus 로고
    • Identification of differentially expressed proteins in human glio-blastoma cell lines and tumors
    • Zhang, R., Tremblay, T. L., McDermid, A., Thibault, P., and Stanimirovic, D. (2003) Identification of differentially expressed proteins in human glio-blastoma cell lines and tumors. Glia 42, 194-208
    • (2003) Glia , vol.42 , pp. 194-208
    • Zhang, R.1    Tremblay, T.L.2    McDermid, A.3    Thibault, P.4    Stanimirovic, D.5
  • 20
    • 76549112005 scopus 로고    scopus 로고
    • EGF potentiated oncogenesis requires a tissue transglutami-nase-dependent signaling pathway leading to Src activation
    • Li, B., Antonyak, M. A., Druso, J. E., Cheng, L., Nikitin, A. Y., and Cerione, R. A. (2010) EGF potentiated oncogenesis requires a tissue transglutami-nase-dependent signaling pathway leading to Src activation. Proc. Natl. Acad. Sci. U.S.A. 107, 1408-1413
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 1408-1413
    • Li, B.1    Antonyak, M.A.2    Druso, J.E.3    Cheng, L.4    Nikitin, A.Y.5    Cerione, R.A.6
  • 21
    • 53349143213 scopus 로고    scopus 로고
    • Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling
    • Cao, L., Petrusca, D. N., Satpathy, M., Nakshatri, H., Petrache, I., and Matei, D. (2008) Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling. Carcinogenesis 29, 1893-1900
    • (2008) Carcinogenesis , vol.29 , pp. 1893-1900
    • Cao, L.1    Petrusca, D.N.2    Satpathy, M.3    Nakshatri, H.4    Petrache, I.5    Matei, D.6
  • 22
    • 42249085070 scopus 로고    scopus 로고
    • Tissue transglutaminase regulates focal adhesion kinase/AKT activation by modulating PTEN expression in pancreatic cancer cells
    • Verma, A., Guha, S., Wang, H., Fok, J. Y., Koul, D., Abbruzzese, J., and Mehta, K. (2008) Tissue transglutaminase regulates focal adhesion kinase/AKT activation by modulating PTEN expression in pancreatic cancer cells. Clin Cancer Res. 14, 1997-2005
    • (2008) Clin Cancer Res. , vol.14 , pp. 1997-2005
    • Verma, A.1    Guha, S.2    Wang, H.3    Fok, J.Y.4    Koul, D.5    Abbruzzese, J.6    Mehta, K.7
  • 25
    • 0037442953 scopus 로고    scopus 로고
    • Microtubule involvement in NIH 3T3 Golgi and MTOC polarity establishment
    • Magdalena, J., Millard, T. H., and Machesky, L. M. (2003) Microtubule involvement in NIH 3T3 Golgi and MTOC polarity establishment. J. Cell Sci. 116, 743-756
    • (2003) J. Cell Sci. , vol.116 , pp. 743-756
    • Magdalena, J.1    Millard, T.H.2    Machesky, L.M.3
  • 27
    • 80054805091 scopus 로고    scopus 로고
    • A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration
    • Boroughs, L. K., Antonyak, M. A., Johnson, J. L., and Cerione, R. A. (2011) A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration. J. Biol. Chem. 286, 37094-37107
    • (2011) J. Biol. Chem. , vol.286 , pp. 37094-37107
    • Boroughs, L.K.1    Antonyak, M.A.2    Johnson, J.L.3    Cerione, R.A.4
  • 28
    • 0038521257 scopus 로고    scopus 로고
    • Activation of the Ras-ERK pathway inhibits retinoic acid-induced stimulation of tissue transglutaminase expression in NIH3T3 cells
    • Antonyak, M. A., McNeill, C. J., Wakshlag, J. J., Boehm, J. E., and Cerione, R. A. (2003) Activation of the Ras-ERK pathway inhibits retinoic acid-induced stimulation of tissue transglutaminase expression in NIH3T3 cells. J. Biol. Chem. 278, 15859-15866
    • (2003) J. Biol. Chem. , vol.278 , pp. 15859-15866
    • Antonyak, M.A.1    McNeill, C.J.2    Wakshlag, J.J.3    Boehm, J.E.4    Cerione, R.A.5
  • 29
    • 51849167782 scopus 로고    scopus 로고
    • Understanding PTEN regulation: PIP2, polarity and protein stability
    • Leslie, N. R., Batty, I. H., Maccario, H., Davidson, L., and Downes, C. P. (2008) Understanding PTEN regulation: PIP2, polarity and protein stability. Oncogene 27, 5464-5476
    • (2008) Oncogene , vol.27 , pp. 5464-5476
    • Leslie, N.R.1    Batty, I.H.2    Maccario, H.3    Davidson, L.4    Downes, C.P.5
  • 30
    • 38349030742 scopus 로고    scopus 로고
    • New insights into PTEN
    • Tamguney, T., and Stokoe, D. (2007) New insights into PTEN. J. Cell Sci. 120, 4071-4079
    • (2007) J. Cell Sci. , vol.120 , pp. 4071-4079
    • Tamguney, T.1    Stokoe, D.2
  • 31
    • 0026657687 scopus 로고
    • Polyoma virus middle T antigen-pp60c-src complex associates with purified phosphatidylinositol 3-kinase in vitro
    • Auger, K. R., Carpenter, C. L., Shoelson, S. E., Piwnica-Worms, H., and Cantley, L. C (1992) Polyoma virus middle T antigen-pp60c-src complex associates with purified phosphatidylinositol 3-kinase in vitro. J. Biol. Chem. 267, 5408-5415
    • (1992) J. Biol. Chem. , vol.267 , pp. 5408-5415
    • Auger, K.R.1    Carpenter, C.L.2    Shoelson, S.E.3    Piwnica-Worms, H.4    Cantley, L.C.5
  • 32
    • 0027214258 scopus 로고
    • The v-Src SH3 domain binds phosphatidylinositol 3'-kinase
    • Liu, X., Marengere, L. E., Koch, C. A., and Pawson, T. (1993) The v-Src SH3 domain binds phosphatidylinositol 3'-kinase. Mol. Cell. Biol. 13, 5225-5232
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5225-5232
    • Liu, X.1    Marengere, L.E.2    Koch, C.A.3    Pawson, T.4
  • 35
    • 0035920129 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase
    • Cuevas, B. D., Lu, Y., Mao, M., Zhang, J., LaPushin, R., Siminovitch, K., and Mills, G. B. (2001) Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase. J. Biol. Chem. 276, 27455-27461
    • (2001) J. Biol. Chem. , vol.276 , pp. 27455-27461
    • Cuevas, B.D.1    Lu, Y.2    Mao, M.3    Zhang, J.4    Lapushin, R.5    Siminovitch, K.6    Mills, G.B.7
  • 36
    • 0026524481 scopus 로고
    • Transformation-defective mutants of polyomavirus middle T antigen associate with phosphatidylinositol 3-kinase (PI3-kinase) but are unable to maintain wild-type levels of PI3-kinase products in intact cells
    • Ling, L. E., Druker, B. J., Cantley, L. C, and Roberts, T. M. (1992) Transformation-defective mutants of polyomavirus middle T antigen associate with phosphatidylinositol 3-kinase (PI3-kinase) but are unable to maintain wild-type levels of PI3-kinase products in intact cells. J. Virol. 66, 1702-1708
    • (1992) J. Virol. , vol.66 , pp. 1702-1708
    • Ling, L.E.1    Druker, B.J.2    Cantley, L.C.3    Roberts, T.M.4
  • 37
    • 0025027872 scopus 로고
    • Production of novel polyphosphoinositides in vivo is linked to cell transformation by polyomavirus middle T antigen
    • Serunian, L. A., Auger, K. R., Roberts, T. M., and Cantley, L. C. (1990) Production of novel polyphosphoinositides in vivo is linked to cell transformation by polyomavirus middle T antigen. J. Virol. 64, 4718-4725
    • (1990) J. Virol. , vol.64 , pp. 4718-4725
    • Serunian, L.A.1    Auger, K.R.2    Roberts, T.M.3    Cantley, L.C.4
  • 38
    • 7944231535 scopus 로고    scopus 로고
    • The road to Src
    • Martin, G. S. (2004) The road to Src. Oncogene 23, 7910-7917
    • (2004) Oncogene , vol.23 , pp. 7910-7917
    • Martin, G.S.1
  • 39
    • 4744351463 scopus 로고    scopus 로고
    • Augmentation of tissue transglutaminase expression and activation by epidermal growth factor inhibit doxorubicin-induced apoptosis in human breast cancer cells
    • Antonyak, M. A., Miller, A. M., Jansen, J. M., Boehm, J. E., Balkman, C. E., Wakshlag, J. J., Page, R. L., and Cerione, R. A. (2004) Augmentation of tissue transglutaminase expression and activation by epidermal growth factor inhibit doxorubicin-induced apoptosis in human breast cancer cells. J. Biol. Chem. 279, 41461-41467
    • (2004) J. Biol. Chem. , vol.279 , pp. 41461-41467
    • Antonyak, M.A.1    Miller, A.M.2    Jansen, J.M.3    Boehm, J.E.4    Balkman, C.E.5    Wakshlag, J.J.6    Page, R.L.7    Cerione, R.A.8
  • 40
    • 84879800043 scopus 로고    scopus 로고
    • A mechanism for the upregulation of EGF receptor levels in glioblastoma
    • Zhang, J., Antonyak, M. A., Singh, G., and Cerione R. A. (2013) A mechanism for the upregulation of EGF receptor levels in glioblastoma. Cell Rep 3, 2008-2020
    • (2013) Cell Rep , vol.3 , pp. 2008-2020
    • Zhang, J.1    Antonyak, M.A.2    Singh, G.3    Cerione, R.A.4


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