Fatty acid chain elongation in palmitate-perfused working rat heart: Mitochondrial acetyl-coa is the source of two-carbon units for chain elongation

Journal of Biological Chemistry

Volumn 289, Issue 14, 2014, Pages 10223-10234

  Kerner, Janos ^a   Minkler, Paul E ^a   Lesnefsky, Edward J ^a,b,c   Hoppel, Charles L ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; ELONGATION; MITOCHONDRIA; OXIDATION; PALMITIC ACID; SATURATED FATTY ACIDS;

ACYLCARNITINES; CARBON-CHAIN LENGTH; CHAIN ELONGATION; CHAIN EXTENDERS; FATTY ACID CHAINS; ISOTOPIC PATTERN; OUTER MEMBRANE; OUTER SURFACE;

CHAINS;

ACETYL COENZYME A; ACYLCARNITINE; ARACHIDYLCARNITINE; CARBON 13; CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 1B; CARNITINE PALMITOYLTRANSFERASE 2; FATTY ACID ESTER; MALONYL COENZYME A; MYRISTOYLCARNITINE; PALMITIC ACID; PALMITOYLCARNITINE; STEAROYLCARNITINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FATTY ACID ANALYSIS; FATTY ACID CHAIN ELONGATION; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; HEART MITOCHONDRION; HEART PERFUSION; ISOLATED HEART; MITOCHONDRIAL MEMBRANE; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

CARNITINE; COENZYME A; FATTY ACID CHAIN ELONGATION, MALONYL-COA, CARNITINE PALMITOYLTRANSFERASE, ACYLCARNITINES, ACYL-COAS; FATTY ACID OXIDATION; HEART; MITOCHONDRIA;

ACETYL COENZYME A; ANIMALS; CARNITINE O-PALMITOYLTRANSFERASE; ENZYME INHIBITORS; MALONYL COENZYME A; MITOCHONDRIA, HEART; MUSCLE PROTEINS; MYOCARDIUM; OXIDATION-REDUCTION; PALMITIC ACID; PALMITOYL COENZYME A; PERFUSION; RATS; RATS, INBRED F344;

EID: 84898065768     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.524314     Document Type: Article

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