메뉴 건너뛰기




Volumn 1794, Issue 3, 2009, Pages 431-437

Mass spectrometric demonstration of the presence of liver carnitine palmitoyltransferase-I (CPT-I) in heart mitochondria of adult rats

Author keywords

Carnitine palmitoyltransferase I; Liver and muscle isoform; Mass spectrometry; Mitochondria; Phosphorylation; Proteomics; Rat heart

Indexed keywords

ALANINE; CARNITINE PALMITOYLTRANSFERASE I; CARNITINE PALMITOYLTRANSFERASE INHIBITOR; MESSENGER RNA; TYROSINE;

EID: 59349120770     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.11.009     Document Type: Article
Times cited : (6)

References (32)
  • 1
    • 0027418315 scopus 로고
    • Cloning, sequencing, expression of a cDNA encoding rat liver carnitine palmitoyltransferase I: direct evidence that a single polypeptide is involved in inhibitor interaction and catalytic function
    • Esser V., Britton C.H., Weis B.C., Foster D.W., and McGarry J.D. Cloning, sequencing, expression of a cDNA encoding rat liver carnitine palmitoyltransferase I: direct evidence that a single polypeptide is involved in inhibitor interaction and catalytic function. J. Biol. Chem. 268 (1993) 5817-5822
    • (1993) J. Biol. Chem. , vol.268 , pp. 5817-5822
    • Esser, V.1    Britton, C.H.2    Weis, B.C.3    Foster, D.W.4    McGarry, J.D.5
  • 2
    • 0029954776 scopus 로고    scopus 로고
    • Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I
    • Yamazaki N., Sinohara Y., Sima A., Yamanaka Y., and Terada H. Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I. Biochim. Biophys. Acta 1307 (1996) 157-161
    • (1996) Biochim. Biophys. Acta , vol.1307 , pp. 157-161
    • Yamazaki, N.1    Sinohara, Y.2    Sima, A.3    Yamanaka, Y.4    Terada, H.5
  • 3
    • 0029862741 scopus 로고    scopus 로고
    • Expression of a cDNA isolated from rat brown adipose tissue and heart identifies the product as the muscle isoform of carnitine palmitoyltransferase I (M-CPT I): M-CPT I is the predominant CPT-I isoform expressed in both white (epididymal) and brown adipocytes
    • Esser V., Brown N.F., Cowan A.T., Foster D.W., and McGarry J.D. Expression of a cDNA isolated from rat brown adipose tissue and heart identifies the product as the muscle isoform of carnitine palmitoyltransferase I (M-CPT I): M-CPT I is the predominant CPT-I isoform expressed in both white (epididymal) and brown adipocytes. J. Biol. Chem. 271 (1996) 6972-6977
    • (1996) J. Biol. Chem. , vol.271 , pp. 6972-6977
    • Esser, V.1    Brown, N.F.2    Cowan, A.T.3    Foster, D.W.4    McGarry, J.D.5
  • 4
    • 0020624753 scopus 로고
    • Observations on the affinity for carnitine, malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat
    • McGarry J.D., Mills S.E., Long C.S., and Foster D.W. Observations on the affinity for carnitine, malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat. Biochem. J. 214 (1983) 21-28
    • (1983) Biochem. J. , vol.214 , pp. 21-28
    • McGarry, J.D.1    Mills, S.E.2    Long, C.S.3    Foster, D.W.4
  • 6
    • 0028091713 scopus 로고
    • Use of a selective inhibitor of liver carnitine palmitoyltransferase I (CPT-I) allows quantification of its contribution to total CPT-I activity in rat heart
    • Weis B.C., Cowan A.T., Brown N., Foster D.W., and McGarry J.D. Use of a selective inhibitor of liver carnitine palmitoyltransferase I (CPT-I) allows quantification of its contribution to total CPT-I activity in rat heart. J. Biol. Chem. 269 (1994) 26443-26448
    • (1994) J. Biol. Chem. , vol.269 , pp. 26443-26448
    • Weis, B.C.1    Cowan, A.T.2    Brown, N.3    Foster, D.W.4    McGarry, J.D.5
  • 7
    • 0028238880 scopus 로고
    • Rat heart expresses two forms of mitochondrial carnitine palmitoyltransferase I
    • Weis B.C., Esser V., Foster D.W., and McGarry J.D. Rat heart expresses two forms of mitochondrial carnitine palmitoyltransferase I. J. Biol. Chem. 269 (1994) 18712-18715
    • (1994) J. Biol. Chem. , vol.269 , pp. 18712-18715
    • Weis, B.C.1    Esser, V.2    Foster, D.W.3    McGarry, J.D.4
  • 8
    • 0028943364 scopus 로고
    • Mitochondrial carnitine palmitoyltransferase I isoform switching in the developing rat heart
    • Brown N.F., Weis B.C., Husti J.E., Foster D.W., and McGarry J.D. Mitochondrial carnitine palmitoyltransferase I isoform switching in the developing rat heart. J. Biol. Chem. 270 (1995) 8952-8957
    • (1995) J. Biol. Chem. , vol.270 , pp. 8952-8957
    • Brown, N.F.1    Weis, B.C.2    Husti, J.E.3    Foster, D.W.4    McGarry, J.D.5
  • 9
    • 0030663919 scopus 로고    scopus 로고
    • Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation
    • Brown N.F., Hill J.K., Esser V., Kirkland J.L., Corkey B., Foster D.W., and McGarry J.D. Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Biochem. J. 327 (1997) 225-231
    • (1997) Biochem. J. , vol.327 , pp. 225-231
    • Brown, N.F.1    Hill, J.K.2    Esser, V.3    Kirkland, J.L.4    Corkey, B.5    Foster, D.W.6    McGarry, J.D.7
  • 10
    • 0031043030 scopus 로고    scopus 로고
    • The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis
    • McGarry J.D., and Brown N.F. The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis. Eur. J. Biochem. 244 (1997) 1-14
    • (1997) Eur. J. Biochem. , vol.244 , pp. 1-14
    • McGarry, J.D.1    Brown, N.F.2
  • 12
    • 0034972285 scopus 로고    scopus 로고
    • Differential regulation of carnitine palmitoyltransferase-I gene isoforms (CPT-I and CPT-I) in the rat heart
    • Cook G.A., Edwards T.L., Jansen M.S., Bahouth S.W., Wilcox H.G., and Park E.A. Differential regulation of carnitine palmitoyltransferase-I gene isoforms (CPT-I and CPT-I) in the rat heart. J. Mol. Cell. Cardiol. 33 (2001) 317-329
    • (2001) J. Mol. Cell. Cardiol. , vol.33 , pp. 317-329
    • Cook, G.A.1    Edwards, T.L.2    Jansen, M.S.3    Bahouth, S.W.4    Wilcox, H.G.5    Park, E.A.6
  • 13
    • 0033841128 scopus 로고    scopus 로고
    • Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction
    • Depre C., Young M.E., Ahuja H.S., Garza N., Davies P.J., and Taegtmeyer H. Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction. J. Mol. Cell. Cardiol. 32 (2000) 985-996
    • (2000) J. Mol. Cell. Cardiol. , vol.32 , pp. 985-996
    • Depre, C.1    Young, M.E.2    Ahuja, H.S.3    Garza, N.4    Davies, P.J.5    Taegtmeyer, H.6
  • 14
    • 7244246894 scopus 로고    scopus 로고
    • Expression of genes participating in regulation of fatty acid and glucose utilization and energy metabolism in developing rat hearts
    • Lavrentyev E.N., He D., and Cook G.A. Expression of genes participating in regulation of fatty acid and glucose utilization and energy metabolism in developing rat hearts. Am. J. Physiol. Heart. Circ. Physiol. 287 (2004) H2035-2042
    • (2004) Am. J. Physiol. Heart. Circ. Physiol. , vol.287
    • Lavrentyev, E.N.1    He, D.2    Cook, G.A.3
  • 15
    • 0032128379 scopus 로고    scopus 로고
    • Impact of protein restriction on the regulation of cardiac carnitine palmitoyltransferase by malonyl-CoA
    • Holness M.J., Priestman D.A., and Sugden M.C. Impact of protein restriction on the regulation of cardiac carnitine palmitoyltransferase by malonyl-CoA. J. Mol. Cell. Cardiol. 30 (1998) 1381-1390
    • (1998) J. Mol. Cell. Cardiol. , vol.30 , pp. 1381-1390
    • Holness, M.J.1    Priestman, D.A.2    Sugden, M.C.3
  • 16
    • 0027456595 scopus 로고
    • Inhibitors of mitochondrial carnitine palmitoyltransferase I limit the action of protease on the enzyme
    • Esser V., Kuwajima M., Britton C.H., Krishnan K., Foster D.W., and McGarry J.D. Inhibitors of mitochondrial carnitine palmitoyltransferase I limit the action of protease on the enzyme. J. Biol. Chem. 268 (1993) 5810-5816
    • (1993) J. Biol. Chem. , vol.268 , pp. 5810-5816
    • Esser, V.1    Kuwajima, M.2    Britton, C.H.3    Krishnan, K.4    Foster, D.W.5    McGarry, J.D.6
  • 17
    • 34247231646 scopus 로고    scopus 로고
    • Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts
    • Sorokina N., O'Donnell J.M., McKinney R.D., Pound K.M., Woldegiorgis G., LaNoue K.F., Ballal K., Taegtmeyer H., Buttrick P.M., and Lewandowski E.D. Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts. Circles 115 (2007) 2033-2041
    • (2007) Circles , vol.115 , pp. 2033-2041
    • Sorokina, N.1    O'Donnell, J.M.2    McKinney, R.D.3    Pound, K.M.4    Woldegiorgis, G.5    LaNoue, K.F.6    Ballal, K.7    Taegtmeyer, H.8    Buttrick, P.M.9    Lewandowski, E.D.10
  • 18
    • 33747177566 scopus 로고    scopus 로고
    • A targeted proteomic approach for the analysis of rat liver mitochondrial outer membrane proteins with extensive sequence coverage
    • Distler A.M., Kerner J., Peterman S.M., and Hoppel C.L. A targeted proteomic approach for the analysis of rat liver mitochondrial outer membrane proteins with extensive sequence coverage. Anal. Biochem. 356 (2006) 18-29
    • (2006) Anal. Biochem. , vol.356 , pp. 18-29
    • Distler, A.M.1    Kerner, J.2    Peterman, S.M.3    Hoppel, C.L.4
  • 19
    • 34247634168 scopus 로고    scopus 로고
    • Posttranslational modifications of rat liver mitochondrial carnitine palmitoyltransferase-I, long-chain acyl-CoA synthetase, and voltage-dependent anion channel
    • Distler A.M., Kerner J., and Hoppel C.L. Posttranslational modifications of rat liver mitochondrial carnitine palmitoyltransferase-I, long-chain acyl-CoA synthetase, and voltage-dependent anion channel. Biochim. Biophys. Acta 1774 (2007) 628-636
    • (2007) Biochim. Biophys. Acta , vol.1774 , pp. 628-636
    • Distler, A.M.1    Kerner, J.2    Hoppel, C.L.3
  • 20
    • 0017666963 scopus 로고
    • An analysis of partial reactions in the overall chain elongation of saturated and unsaturated fatty acids by rat liver microsomes
    • Bernert Jr. J.T., and Sprecher H. An analysis of partial reactions in the overall chain elongation of saturated and unsaturated fatty acids by rat liver microsomes. J. Biol. Chem. 252 (1977) 6736-6744
    • (1977) J. Biol. Chem. , vol.252 , pp. 6736-6744
    • Bernert Jr., J.T.1    Sprecher, H.2
  • 22
    • 0032483331 scopus 로고    scopus 로고
    • The malonyl-CoA-sensitive form of carnitine palmitoyltransferase is not localized exclusively in the outer membrane of rat liver mitochondria
    • Hoppel C.L., Kerner J., Turkaly P., Turkaly J., and Tandler B. The malonyl-CoA-sensitive form of carnitine palmitoyltransferase is not localized exclusively in the outer membrane of rat liver mitochondria. J. Biol. Chem. 273 (1998) 23495-23503
    • (1998) J. Biol. Chem. , vol.273 , pp. 23495-23503
    • Hoppel, C.L.1    Kerner, J.2    Turkaly, P.3    Turkaly, J.4    Tandler, B.5
  • 23
    • 4444277089 scopus 로고    scopus 로고
    • Phosphorylation of rat liver mitochondrial carnitine palmitoyltransferase-I: effect on the kinetic properties of the enzyme
    • Kerner J., Distler A.M., Parland W., Peterman S.M., and Hoppel C.L. Phosphorylation of rat liver mitochondrial carnitine palmitoyltransferase-I: effect on the kinetic properties of the enzyme. J. Biol. Chem. 279 (2004) 41104-41113
    • (2004) J. Biol. Chem. , vol.279 , pp. 41104-41113
    • Kerner, J.1    Distler, A.M.2    Parland, W.3    Peterman, S.M.4    Hoppel, C.L.5
  • 24
    • 77049143386 scopus 로고
    • The determination of enzyme inhibitor constants
    • Dixon M. The determination of enzyme inhibitor constants. Biochem. J. 55 (1953) 170-171
    • (1953) Biochem. J. , vol.55 , pp. 170-171
    • Dixon, M.1
  • 25
    • 0017740356 scopus 로고
    • Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle
    • Palmer J.W., Tandler B., and Hoppel C.L. Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle. J. Biol. Chem. 252 (1977) 8731-8739
    • (1977) J. Biol. Chem. , vol.252 , pp. 8731-8739
    • Palmer, J.W.1    Tandler, B.2    Hoppel, C.L.3
  • 26
    • 0036498771 scopus 로고    scopus 로고
    • Isolation of hepatic mitochondrial contact sites: previously unrecognized inner membrane components
    • Hoppel C., Kerner J., Turkaly P., Minkler P., and Tandler B. Isolation of hepatic mitochondrial contact sites: previously unrecognized inner membrane components. Anal. Biochem. 302 (2002) 60-69
    • (2002) Anal. Biochem. , vol.302 , pp. 60-69
    • Hoppel, C.1    Kerner, J.2    Turkaly, P.3    Minkler, P.4    Tandler, B.5
  • 27
    • 0018215524 scopus 로고
    • Variation in tissue carnitine concentrations with age and sex in the rat
    • Borum P.R. Variation in tissue carnitine concentrations with age and sex in the rat. Biochem. J. 176 (1978) 677-681
    • (1978) Biochem. J. , vol.176 , pp. 677-681
    • Borum, P.R.1
  • 28
    • 0031907952 scopus 로고    scopus 로고
    • The liver isoform of carnitine palmitoyltransferase I is activated in neonatal rat cardiac myocytes by hypoxia
    • Wang D., Xia Y., Buja M., and McMillin J.B. The liver isoform of carnitine palmitoyltransferase I is activated in neonatal rat cardiac myocytes by hypoxia. Mol. Cell. Biochem. 180 (1998) 163-170
    • (1998) Mol. Cell. Biochem. , vol.180 , pp. 163-170
    • Wang, D.1    Xia, Y.2    Buja, M.3    McMillin, J.B.4
  • 29
    • 0029879376 scopus 로고    scopus 로고
    • Increased expression of carnitine palmitoyltransferase I gene is repressed by administering l-carnitine in the hearts of carnitine-deficient juvenile visceral steatosis mice
    • Uenaka R., Kuwajima M., Ono A., Matsuzawa Y., Hayakawa J., Inohara N., Kagawa Y., and Ohta S. Increased expression of carnitine palmitoyltransferase I gene is repressed by administering l-carnitine in the hearts of carnitine-deficient juvenile visceral steatosis mice. J. Biochem. 119 (1996) 533-540
    • (1996) J. Biochem. , vol.119 , pp. 533-540
    • Uenaka, R.1    Kuwajima, M.2    Ono, A.3    Matsuzawa, Y.4    Hayakawa, J.5    Inohara, N.6    Kagawa, Y.7    Ohta, S.8
  • 31
    • 0034142251 scopus 로고    scopus 로고
    • The first 28 N-terminal amino acid residues of human heart muscle carnitine palmitoyltransferase I are essential for malonyl CoA sensitivity and high affinity binding
    • Shi J., Zhu H., Arvidson D.N., and Woldegiorgis G. The first 28 N-terminal amino acid residues of human heart muscle carnitine palmitoyltransferase I are essential for malonyl CoA sensitivity and high affinity binding. Biochemistry 39 (2000) 712-717
    • (2000) Biochemistry , vol.39 , pp. 712-717
    • Shi, J.1    Zhu, H.2    Arvidson, D.N.3    Woldegiorgis, G.4
  • 32
    • 0032528903 scopus 로고    scopus 로고
    • Expression of novel isoforms of carnitine palmitoyltransferase I (CPT-1) generated by alternative splicing of the CPT-Iβ gene
    • Yu G.S., Lu Y.C., and Gulick T. Expression of novel isoforms of carnitine palmitoyltransferase I (CPT-1) generated by alternative splicing of the CPT-Iβ gene. Biochem. J. 334 (1998) 225-231
    • (1998) Biochem. J. , vol.334 , pp. 225-231
    • Yu, G.S.1    Lu, Y.C.2    Gulick, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.