-
1
-
-
33646018341
-
Fatty acid elongases in mammals: Their regulation and roles in metabolism
-
Jakobsson, A., Westerberg, R., and Jacobsson, A. (2006) Fatty acid elongases in mammals: their regulation and roles in metabolism. Prog. Lipid Res. 45, 237-249
-
(2006)
Prog. Lipid Res.
, vol.45
, pp. 237-249
-
-
Jakobsson, A.1
Westerberg, R.2
Jacobsson, A.3
-
2
-
-
76749132709
-
The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice
-
Guillou, H., Zadravec, D., Martin, P.G., and Jacobsson, A. (2010) The key roles of elongases and desaturases in mammalian fatty acid metabolism: insights from transgenic mice. Prog. Lipid Res. 49, 186-199
-
(2010)
Prog. Lipid Res.
, vol.49
, pp. 186-199
-
-
Guillou, H.1
Zadravec, D.2
Martin, P.G.3
Jacobsson, A.4
-
3
-
-
78649873920
-
ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis
-
Ohno, Y., Suto, S., Yamanaka, M., Mizutani, Y., Mitsutake, S., Igarashi, Y., Sassa, T., and Kihara, A. (2010) ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis. Proc. Natl. Acad. Sci. USA. 107, 18439-18444
-
(2010)
Proc. Natl. Acad. Sci. USA.
, vol.107
, pp. 18439-18444
-
-
Ohno, Y.1
Suto, S.2
Yamanaka, M.3
Mizutani, Y.4
Mitsutake, S.5
Igarashi, Y.6
Sassa, T.7
Kihara, A.8
-
4
-
-
33947286240
-
Fatty acid synthesis and elongation in yeast
-
Tehlivets, O., Scheuringer, K., and Kohlwein, S.D. (2007) Fatty acid synthesis and elongation in yeast. Biochim. Biophys. Acta 1771, 255-270
-
(2007)
Biochim. Biophys. Acta
, vol.1771
, pp. 255-270
-
-
Tehlivets, O.1
Scheuringer, K.2
Kohlwein, S.D.3
-
5
-
-
0037144543
-
The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase
-
Han, G., Gable, K., Kohlwein, S.D., Beaudoin, F., Napier, J.A., and Dunn, T.M. (2002) The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase. J. Biol. Chem. 277, 35440-35449
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 35440-35449
-
-
Han, G.1
Gable, K.2
Kohlwein, S.D.3
Beaudoin, F.4
Napier, J.A.5
Dunn, T.M.6
-
6
-
-
0037470063
-
Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade
-
Moon, Y.A. and Horton, J.D. (2003) Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade. J. Biol. Chem. 278, 7335-7343
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7335-7343
-
-
Moon, Y.A.1
Horton, J.D.2
-
7
-
-
34547947625
-
A molecular caliper mechanism for determining very long-chain fatty acid length
-
Denic, V. and Weissman, J.S. (2007) A molecular caliper mechanism for determining very long-chain fatty acid length. Cell 130, 663-677
-
(2007)
Cell
, vol.130
, pp. 663-677
-
-
Denic, V.1
Weissman, J.S.2
-
8
-
-
45549086681
-
Characterization of four mammalian 3-hydroxyacyl-CoA dehydratases involved in very long-chain fatty acid synthesis
-
Ikeda, M., Kanao, Y., Yamanaka, M., Sakuraba, H., Mizutani, Y., Igarashi, Y., and Kihara, A. (2008) Characterization of four mammalian 3-hydroxyacyl-CoA dehydratases involved in very long-chain fatty acid synthesis. FEBS Lett. 582, 2435-2440
-
(2008)
FEBS Lett.
, vol.582
, pp. 2435-2440
-
-
Ikeda, M.1
Kanao, Y.2
Yamanaka, M.3
Sakuraba, H.4
Mizutani, Y.5
Igarashi, Y.6
Kihara, A.7
-
9
-
-
0034749756
-
Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae
-
Kohlwein, S.D., Eder, S., Oh, C.S., Martin, C.E., Gable, K, Bacikova, D., and Dunn, T. (2001) Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae. Mol. Cell. Biol. 21, 109-125
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 109-125
-
-
Kohlwein, S.D.1
Eder, S.2
Oh, C.S.3
Martin, C.E.4
Gable, K.5
Bacikova, D.6
Dunn, T.7
-
10
-
-
78650761943
-
Hetero-oligomeric interactions of an ELOVL4 mutant protein: Implications in the molecular mechanism of Stargardt-3 macular dystrophy
-
Okuda, A., Naganuma, T., Ohno, Y., Abe, K, Yamagata, M., Igarashi, Y., and Kihara, A. (2010) Hetero-oligomeric interactions of an ELOVL4 mutant protein: implications in the molecular mechanism of Stargardt-3 macular dystrophy. Mol. Vis. 16, 2438-2445
-
(2010)
Mol. Vis.
, vol.16
, pp. 2438-2445
-
-
Okuda, A.1
Naganuma, T.2
Ohno, Y.3
Abe, K.4
Yamagata, M.5
Igarashi, Y.6
Kihara, A.7
-
11
-
-
78049455554
-
Characterization of HACD1 K64Q mutant found in arrhythmogenic right ventricular dysplasia patients
-
Konishi, H., Okuda, A., Ohno, Y., and Kihara, A. (2010) Characterization of HACD1 K64Q mutant found in arrhythmogenic right ventricular dysplasia patients. J. Biochem. 148, 617-622
-
(2010)
J. Biochem.
, vol.148
, pp. 617-622
-
-
Konishi, H.1
Okuda, A.2
Ohno, Y.3
Kihara, A.4
-
12
-
-
80054087224
-
Biochemical characterization of the very long-chain fatty acid elongase ELOVL7
-
Naganuma, T., Sato, Y., Sassa, T., Ohno, Y., and Kihara, A. (2011) Biochemical characterization of the very long-chain fatty acid elongase ELOVL7. FEBS Lett. 585, 3337-3341
-
(2011)
FEBS Lett.
, vol.585
, pp. 3337-3341
-
-
Naganuma, T.1
Sato, Y.2
Sassa, T.3
Ohno, Y.4
Kihara, A.5
-
13
-
-
77953490959
-
Retinal very long-chain PUFAs: New insights from studies on ELOVL4 protein
-
Agbaga, M.P., Mandal, M.N., and Anderson, R.E. (2010) Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein. J. Lipid Res. 51, 1624-1642
-
(2010)
J. Lipid Res.
, vol.51
, pp. 1624-1642
-
-
Agbaga, M.P.1
Mandal, M.N.2
Anderson, R.E.3
-
14
-
-
0035168415
-
A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy
-
Zhang, K, Kniazeva, M., Han, M., Li, W., Yu, Z., Yang, Z., Li, Y., Metzker, M.L., Allikmets, R., Zack, D.J., Kakuk, L.E., Lagali, P.S., Wong, P.W., MacDonald, I.M., Sieving, P.A., Figueroa, D.J., Austin, C.P., Gould, R.J., Ayyagari, R., and Petrukhin, K. (2001) A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy. Nat. Genet. 27, 89-93
-
(2001)
Nat. Genet.
, vol.27
, pp. 89-93
-
-
Zhang, K.1
Kniazeva, M.2
Han, M.3
Li, W.4
Yu, Z.5
Yang, Z.6
Li, Y.7
Metzker, M.L.8
Allikmets, R.9
Zack, D.J.10
Kakuk, L.E.11
Lagali, P.S.12
Wong, P.W.13
MacDonald, I.M.14
Sieving, P.A.15
Figueroa, D.J.16
Austin, C.P.17
Gould, R.J.18
Ayyagari, R.19
Petrukhin, K.20
more..
-
15
-
-
1542509344
-
Characterization of mouse orthologue of ELOVL4: Genomic organization and spatial and temporal expression
-
Mandal, M.N., Ambasudhan, R., Wong, P.W., Gage, P.J., Sieving, P.A., and Ayyagari, R. (2004) Characterization of mouse orthologue of ELOVL4: genomic organization and spatial and temporal expression. Genomics 83, 626-635
-
(2004)
Genomics
, vol.83
, pp. 626-635
-
-
Mandal, M.N.1
Ambasudhan, R.2
Wong, P.W.3
Gage, P.J.4
Sieving, P.A.5
Ayyagari, R.6
-
16
-
-
34247520569
-
Metabolism and biological functions of two phos-phorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate
-
Kihara, A., Mitsutake, S., Mizutani, Y., and Igarashi, Y. (2007) Metabolism and biological functions of two phos-phorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate. Prog. Lipid Res. 46, 126-144
-
(2007)
Prog. Lipid Res.
, vol.46
, pp. 126-144
-
-
Kihara, A.1
Mitsutake, S.2
Mizutani, Y.3
Igarashi, Y.4
-
17
-
-
41949140023
-
Characterization of ceramide synthase 2: Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
-
Laviad, E.L., Albee, L., Pankova-Kholmyansky, I., Epstein, S., Park, H, Merrill, A.H. Jr., and Futerman, A.H. (2008) Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J. Biol. Chem. 283, 5677-5584
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5677-5584
-
-
Laviad, E.L.1
Albee, L.2
Pankova-Kholmyansky, I.3
Epstein, S.4
Park, H.5
Merrill, Jr.A.H.6
Futerman, A.H.7
-
18
-
-
67349094025
-
Ceramide biosynthesis in keratino-cyte and its role in skin function
-
Mizutani, Y., Mitsutake, S., Tsuji, K, Kihara, A., and Igarashi, Y. (2009) Ceramide biosynthesis in keratino-cyte and its role in skin function. Biochimie 91, 784-790
-
(2009)
Biochimie
, vol.91
, pp. 784-790
-
-
Mizutani, Y.1
Mitsutake, S.2
Tsuji, K.3
Kihara, A.4
Igarashi, Y.5
-
19
-
-
33748747214
-
LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity
-
Mizutani, Y., Kihara, A., and Igarashi, Y. (2006) LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity. Biochem. J. 398, 531-538
-
(2006)
Biochem. J.
, vol.398
, pp. 531-538
-
-
Mizutani, Y.1
Kihara, A.2
Igarashi, Y.3
-
20
-
-
77951932472
-
Significance of glycosphingolipid fatty acid chain length on membrane microdomain-mediated signal transduction
-
Iwabuchi, K, Nakayama, H, Iwahara, C, and Takamori, K. (2010) Significance of glycosphingolipid fatty acid chain length on membrane microdomain-mediated signal transduction. FEBS Lett. 584, 1642-1652
-
(2010)
FEBS Lett.
, vol.584
, pp. 1642-1652
-
-
Iwabuchi, K.1
Nakayama, H.2
Iwahara, C.3
Takamori, K.4
-
21
-
-
84861216157
-
A shift in sphingolipid composition from C24 to C16 increases susceptibility to apoptosis in HeLa cells
-
Sassa, T., Suto, S., Okayasu, Y., and Kihara, A. (2012) A shift in sphingolipid composition from C24 to C16 increases susceptibility to apoptosis in HeLa cells. Biochim. Biophys. Acta 1821, 1031-1037
-
(2012)
Biochim. Biophys. Acta
, vol.1821
, pp. 1031-1037
-
-
Sassa, T.1
Suto, S.2
Okayasu, Y.3
Kihara, A.4
-
22
-
-
70450240715
-
Adult ceramide synthase 2 (CerS2) deficient mice exhibit myelin sheath defects, cerebellar degeneration and hepatocarcinomas
-
Imgrund, S., Hartmann, D., Farwanah, H., Eckhardt, M., Sandhoff, R., Degen, J., Gieselmann, V., Sandhoff, K., and Willecke, K. (2009) Adult ceramide synthase 2 (CerS2) deficient mice exhibit myelin sheath defects, cerebellar degeneration and hepatocarcinomas. J. Biol. Chem. 284, 33549-33560
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 33549-33560
-
-
Imgrund, S.1
Hartmann, D.2
Farwanah, H.3
Eckhardt, M.4
Sandhoff, R.5
Degen, J.6
Gieselmann, V.7
Sandhoff, K.8
Willecke, K.9
-
23
-
-
77951216913
-
A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy
-
Pewzner-Jung, Y., Brenner, O., Braun, S., Laviad, E.L., Ben-Dor, S., Feldmesser, E., Horn-Saban, S., Amann-Zalcenstein, D., Raanan, C, Berkutzki, T., Erez-Roman, R., Ben David, O., Levy, M., Holzman, D., Park, H., Nyska, A., Merrill, A.H. Jr., and Futerman, A.H. (2010) A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy. J. Biol. Chem. 285, 10911-10923
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 10911-10923
-
-
Pewzner-Jung, Y.1
Brenner, O.2
Braun, S.3
Laviad, E.L.4
Ben-Dor, S.5
Feldmesser, E.6
Horn-Saban, S.7
Amann-Zalcenstein, D.8
Raanan, C.9
Berkutzki, T.10
Erez-Roman, R.11
Ben David, O.12
Levy, M.13
Holzman, D.14
Park, H.15
Nyska, A.16
Merrill, Jr.A.H.17
Futerman, A.H.18
-
24
-
-
45449109994
-
Omega-O-acyl-ceramide, a lipid essential for mammalian survival
-
Uchida, Y. and Holleran, W.M. (2008) Omega-O-acyl-ceramide, a lipid essential for mammalian survival. J. Dermatol. Sci. 51, 77-87
-
(2008)
J. Dermatol. Sci.
, vol.51
, pp. 77-87
-
-
Uchida, Y.1
Holleran, W.M.2
-
25
-
-
50949109754
-
Characterization of overall ceramide species in human stratum corneum
-
Masukawa, Y., Narita, H., Shimizu, E., Kondo, N, Sugai, Y., Oba, T., Homma, R., Ishikawa, J., Takagi, Y., Kitahara, T., Takema, Y., and Kita, K. (2008) Characterization of overall ceramide species in human stratum corneum. J. Lipid Res. 49, 1466-1476
-
(2008)
J. Lipid Res.
, vol.49
, pp. 1466-1476
-
-
Masukawa, Y.1
Narita, H.2
Shimizu, E.3
Kondo, N.4
Sugai, Y.5
Oba, T.6
Homma, R.7
Ishikawa, J.8
Takagi, Y.9
Kitahara, T.10
Takema, Y.11
Kita, K.12
-
26
-
-
34047174936
-
Loss of functional ELOVL4 depletes very long-chain fatty acids (>C28) and the unique oO-acylceramides in skin leading to neonatal death
-
Vasireddy, V., Uchida, Y., Salem, N. Jr., Kim, S.Y., Mandal, M.N., Reddy, G.B., Bodepudi, R., Alderson, N.L., Brown, J.C., Hama, H., Dlugosz, A., Elias, P.M., Holleran, W.M., and Ayyagari, R. (2007) Loss of functional ELOVL4 depletes very long-chain fatty acids (>C28) and the unique oO-acylceramides in skin leading to neonatal death. Hum. Mol. Genet. 16, 471-482
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 471-482
-
-
Vasireddy, V.1
Uchida, Y.2
Salem, Jr.N.3
Kim, S.Y.4
Mandal, M.N.5
Reddy, G.B.6
Bodepudi, R.7
Alderson, N.L.8
Brown, J.C.9
Hama, H.10
Dlugosz, A.11
Elias, P.M.12
Holleran, W.M.13
Ayyagari, R.14
-
27
-
-
33846924619
-
Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival
-
Cameron, D.J., Tong, Z., Yang, Z., Kaminoh, J., Kamiyah, S., Chen, H., Zeng, J., Chen, Y., Luo, L., and Zhang, K. (2007) Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival. Int. J. Biol. Sci. 3, 111-119
-
(2007)
Int. J. Biol. Sci.
, vol.3
, pp. 111-119
-
-
Cameron, D.J.1
Tong, Z.2
Yang, Z.3
Kaminoh, J.4
Kamiyah, S.5
Chen, H.6
Zeng, J.7
Chen, Y.8
Luo, L.9
Zhang, K.10
-
28
-
-
84855916623
-
Loss of ceramide synthase 3 causes lethal skin barrier disruption
-
Jennemann, R., Rabionet, M., Gorgas, K., Epstein, S., Dalpke, A., Rothermel, U., Bayerle, A., van der Hoeven, F., Imgrund, S., Kirsch, J., Nickel, W., Willecke, K, Riezman, H., Grone, HJ., and Sandhoff, R. (2011) Loss of ceramide synthase 3 causes lethal skin barrier disruption. Hum. Mol. Genet. 21, 586-608
-
(2011)
Hum. Mol. Genet.
, vol.21
, pp. 586-608
-
-
Jennemann, R.1
Rabionet, M.2
Gorgas, K.3
Epstein, S.4
Dalpke, A.5
Rothermel, U.6
Bayerle, A.7
Van Der Hoeven, F.8
Imgrund, S.9
Kirsch, J.10
Nickel, W.11
Willecke, K.12
Riezman, H.13
Grone, H.J.14
Sandhoff, R.15
-
29
-
-
0036179718
-
Dietary essential fatty acids and brain function: A developmental perspective on mechanisms
-
Wainwright, P.E. (2002) Dietary essential fatty acids and brain function: a developmental perspective on mechanisms. Proc. Nutr. Soc. 61, 61-69
-
(2002)
Proc. Nutr. Soc.
, vol.61
, pp. 61-69
-
-
Wainwright, P.E.1
-
30
-
-
8844256502
-
The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina
-
SanGiovanni, J.P. and Chew, E.Y. (2005) The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog. Retin. Eye Res. 24, 87-138
-
(2005)
Prog. Retin. Eye Res.
, vol.24
, pp. 87-138
-
-
Sangiovanni, J.P.1
Chew, E.Y.2
-
31
-
-
77957942833
-
Specialized pro-resolving lipid mediators in the inflammatory response: An update
-
Bannenberg, G and Serhan, C.N. (2010) Specialized pro-resolving lipid mediators in the inflammatory response: an update. Biochim. Biophys. Acta 1801, 1260-1273
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 1260-1273
-
-
Bannenberg, G.1
Serhan, C.N.2
-
32
-
-
60549107724
-
Maresins: Novel macrophage mediators with potent antiinflammatory and proresolving actions
-
Serhan, C.N., Yang, R., Martinod, K, Kasuga, K, Pillai, P.S., Porter, T.F., Oh, S.F., and Spite, M. (2009) Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions. J. Exp. Med. 206, 15-23
-
(2009)
J. Exp. Med.
, vol.206
, pp. 15-23
-
-
Serhan, C.N.1
Yang, R.2
Martinod, K.3
Kasuga, K.4
Pillai, P.S.5
Porter, T.F.6
Oh, S.F.7
Spite, M.8
-
33
-
-
0038013967
-
Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation
-
Hong, S., Gronert, K, Devchand, P.R., Moussignac, R.L., and Serhan, C.N. (2003) Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J. Biol. Chem. 278, 14677-14687
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14677-14687
-
-
Hong, S.1
Gronert, K.2
Devchand, P.R.3
Moussignac, R.L.4
Serhan, C.N.5
-
34
-
-
0023805970
-
The occurrence of polyenoic very long chain fatty acids with greater than 32 carbon atoms in molecular species of phosphatidylcholine in normal and peroxisome-deficient (Zellweger's syndrome) brain
-
Poulos, A., Sharp, P., Johnson, D., and Easton, C. (1988) The occurrence of polyenoic very long chain fatty acids with greater than 32 carbon atoms in molecular species of phosphatidylcholine in normal and peroxisome-deficient (Zellweger's syndrome) brain. Biochem. J. 253, 645-650
-
(1988)
Biochem. J.
, vol.253
, pp. 645-650
-
-
Poulos, A.1
Sharp, P.2
Johnson, D.3
Easton, C.4
-
35
-
-
78249249604
-
Identification and quantification of phosphatidylcholines containing very-long-chain polyunsaturated fatty acid in bovine and human retina using liquid chromatography/tandem mass spectrometry
-
Berdeaux, O., Juaneda, P., Martine, L., Cabaret, S., Bretillon, L., and Acar, N. (2010) Identification and quantification of phosphatidylcholines containing very-long-chain polyunsaturated fatty acid in bovine and human retina using liquid chromatography/tandem mass spectrometry. J. Chromatogr. A 1217, 7738-7748
-
(2010)
J. Chromatogr. A
, vol.1217
, pp. 7738-7748
-
-
Berdeaux, O.1
Juaneda, P.2
Martine, L.3
Cabaret, S.4
Bretillon, L.5
Acar, N.6
-
36
-
-
77951204243
-
Genetics and molecular pathology of Stargardt-like macular degeneration
-
Vasireddy, V., Wong, P., and Ayyagari, R. (2010) Genetics and molecular pathology of Stargardt-like macular degeneration. Prog. Retin. Eye Res. 29, 191-207
-
(2010)
Prog. Retin. Eye Res.
, vol.29
, pp. 191-207
-
-
Vasireddy, V.1
Wong, P.2
Ayyagari, R.3
-
37
-
-
36049004344
-
A Stargardt disease-3 mutation in the mouse Elovl4 gene causes retinal deficiency of C32-C36 acyl phosphatidylcholines
-
McMahon, A., Jackson, S.N., Woods, A.S., and Kedzierski, W. (2007) A Stargardt disease-3 mutation in the mouse Elovl4 gene causes retinal deficiency of C32-C36 acyl phosphatidylcholines. FEBS Lett. 581, 5459-5463
-
(2007)
FEBS Lett.
, vol.581
, pp. 5459-5463
-
-
McMahon, A.1
Jackson, S.N.2
Woods, A.S.3
Kedzierski, W.4
-
38
-
-
77951886452
-
Very long chain sphingolipids: Tissue expression, function and synthesis
-
Sandhoff, R. (2010) Very long chain sphingolipids: tissue expression, function and synthesis. FEBS Lett. 584, 1907-1913
-
(2010)
FEBS Lett.
, vol.584
, pp. 1907-1913
-
-
Sandhoff, R.1
-
39
-
-
45149116217
-
Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: A link to ceramide synthase-3
-
Rabionet, M., van der Spoel, A.C., Chuang, CC, von Tumpling-Radosta, B., Litjens, M., Bouwmeester, D., Hellbusch, C.C., Korner, C, Wiegandt, H., Gorgas, K, Platt, F.M., Grone, HJ., and Sandhoff, R. (2008) Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3. J. Biol. Chem. 283, 13357-13369
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13357-13369
-
-
Rabionet, M.1
Van Der Spoel, A.C.2
Chuang, C.C.3
Von Tumpling-Radosta, B.4
Litjens, M.5
Bouwmeester, D.6
Hellbusch, C.C.7
Korner, C.8
Wiegandt, H.9
Gorgas, K.10
Platt, F.M.11
Grone, H.J.12
Sandhoff, R.13
-
40
-
-
34547132811
-
Ceramides and sphingomyelins with high proportions of very long-chain polyunsaturated fatty acids in mammalian germ cells
-
Furland, N.E., Zanetti, S.R., Oresti, GM., Maldonado, E.N., and Aveldano, M.I. (2007) Ceramides and sphingomyelins with high proportions of very long-chain polyunsaturated fatty acids in mammalian germ cells. J. Biol. Chem. 282, 18141-18150
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 18141-18150
-
-
Furland, N.E.1
Zanetti, S.R.2
Oresti, G.M.3
Maldonado, E.N.4
Aveldano, M.I.5
-
41
-
-
83555175990
-
Recessive mutations in ELOVL4 cause ichthyosis, intellectual disability, and spastic quadriplegia
-
Aldahmesh, M.A., Mohamed, J.Y., Alkuraya, H.S., Verma, I.C., Puri, R.D., Alaiya, A.A., Rizzo, W.B., and Alkuraya, F.S. (2011) Recessive mutations in ELOVL4 cause ichthyosis, intellectual disability, and spastic quadriplegia. Am. J. Hum. Genet. 89, 745-750
-
(2011)
Am. J. Hum. Genet.
, vol.89
, pp. 745-750
-
-
Aldahmesh, M.A.1
Mohamed, J.Y.2
Alkuraya, H.S.3
Verma, I.C.4
Puri, R.D.5
Alaiya, A.A.6
Rizzo, W.B.7
Alkuraya, F.S.8
-
42
-
-
79956066715
-
The roles of ABCA12 in keratino-cyte differentiation and lipid barrier formation in the epidermis
-
Akiyama, M. (2011) The roles of ABCA12 in keratino-cyte differentiation and lipid barrier formation in the epidermis. Dermatoendocrinol. 3, 107-112
-
(2011)
Dermatoendocrinol.
, vol.3
, pp. 107-112
-
-
Akiyama, M.1
-
43
-
-
79952605814
-
Exome sequencing reveals a novel mutation for autosomal recessive non-syndromic mental retardation in the TECR gene on chromosome 19p13
-
Caliskan, M., Chong, J.X., Uricchio, L., Anderson, R., Chen, P., Sougnez, C, Garimella, K, Gabriel, S.B., dePristo, M.A., Shakir, K, Matern, D., Das, S., Waggoner, D., Nicolae, D.L., and Ober, C. (2011) Exome sequencing reveals a novel mutation for autosomal recessive non-syndromic mental retardation in the TECR gene on chromosome 19p13. Hum. Mol. Genet. 20, 1285-1289
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1285-1289
-
-
Caliskan, M.1
Chong, J.X.2
Uricchio, L.3
Anderson, R.4
Chen, P.5
Sougnez, C.6
Garimella, K.7
Gabriel, S.B.8
Depristo, M.A.9
Shakir, K.10
Matern, D.11
Das, S.12
Waggoner, D.13
Nicolae, D.L.14
Ober, C.15
-
44
-
-
77950239532
-
Hydroxysteroid (17b) dehydrogenase 12 is essential for mouse organogenesis and embryonic survival
-
Rantakari, P., Lagerbohm, H., Kaimainen, M., Suomela, J.P., Strauss, L., Sainio, K, Pakarinen, P., and Poutanen, M. (2010) Hydroxysteroid (17b) dehydrogenase 12 is essential for mouse organogenesis and embryonic survival. Endocrinology 151, 1893-1901
-
(2010)
Endocrinology
, vol.151
, pp. 1893-1901
-
-
Rantakari, P.1
Lagerbohm, H.2
Kaimainen, M.3
Suomela, J.P.4
Strauss, L.5
Sainio, K.6
Pakarinen, P.7
Poutanen, M.8
-
45
-
-
0034601696
-
Human protein tyrosine phosphatase-like gene: Expression profile, genomic structure, and mutation analysis in families with ARVD
-
Li, D., Gonzalez, O., Bachinski, L.L., and Roberts, R. (2000) Human protein tyrosine phosphatase-like gene: expression profile, genomic structure, and mutation analysis in families with ARVD. Gene 256, 237-243
-
(2000)
Gene
, vol.256
, pp. 237-243
-
-
Li, D.1
Gonzalez, O.2
Bachinski, L.L.3
Roberts, R.4
-
46
-
-
20444433182
-
SINE exonic insertion in the PTPLA gene leads to multiple splicing defects and segregates with the autosomal recessive centronuclear myopathy in dogs
-
Pele, M., Tiret, L., Kessler, J.L., Blot, S., and Panthier, J.J. (2005) SINE exonic insertion in the PTPLA gene leads to multiple splicing defects and segregates with the autosomal recessive centronuclear myopathy in dogs. Hum. Mol. Genet. 14, 1417-1427
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 1417-1427
-
-
Pele, M.1
Tiret, L.2
Kessler, J.L.3
Blot, S.4
Panthier, J.J.5
-
47
-
-
42649092901
-
Mechanisms of disease: Molecular genetics of arrhythmo-genic right ventricular dysplasia/cardiomyopathy
-
Awad, M.M., Calkins, H, and Judge, D.P. (2008) Mechanisms of disease: molecular genetics of arrhythmo-genic right ventricular dysplasia/ cardiomyopathy. Nat. Clin. Pract. Cardiovasc. Med. 5, 258-267
-
(2008)
Nat. Clin. Pract. Cardiovasc. Med.
, vol.5
, pp. 258-267
-
-
Awad, M.M.1
Calkins, H.2
Judge, D.P.3
-
48
-
-
84864042465
-
X-linked adrenoleukodystrophy: Clinical, metabolic, genetic and pathophysiological aspects
-
Kemp, S., Berger, J., and Aubourg, P. (2012) X-linked adrenoleukodystrophy: clinical, metabolic, genetic and pathophysiological aspects. Biochim. Biophys. Acta 1822, 1465-1474
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 1465-1474
-
-
Kemp, S.1
Berger, J.2
Aubourg, P.3
-
49
-
-
4744371532
-
Peroxisomes, lipid metabolism, and peroxisomal disorders
-
Wanders, R.J. (2004) Peroxisomes, lipid metabolism, and peroxisomal disorders. Mol. Genet. Metab. 83, 16-27
-
(2004)
Mol. Genet. Metab.
, vol.83
, pp. 16-27
-
-
Wanders, R.J.1
-
50
-
-
60549111243
-
Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry
-
Ejsing, C.S., Sampaio, J.L., Surendranath, V., Duchoslav, E., Ekroos, K, Klemm, R.W., Simons, K, and Shevchenko, A. (2009) Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry. Proc. Natl. Acad. Sci. USA 106, 2136-2141
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 2136-2141
-
-
Ejsing, C.S.1
Sampaio, J.L.2
Surendranath, V.3
Duchoslav, E.4
Ekroos, K.5
Klemm, R.W.6
Simons, K.7
Shevchenko, A.8
-
51
-
-
0027438892
-
A suppressor gene that enables Saccharomyces cerevisiae to grow without making sphingolipids encodes a protein that resembles an Escherichia coli fatty acyltransferase
-
Nagiec, M.M., Wells, G.B., Lester, R.L., and Dickson, R.C. (1993) A suppressor gene that enables Saccharomyces cerevisiae to grow without making sphingolipids encodes a protein that resembles an Escherichia coli fatty acyltransferase. J. Biol. Chem. 268, 22156-22163
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 22156-22163
-
-
Nagiec, M.M.1
Wells, G.B.2
Lester, R.L.3
Dickson, R.C.4
-
52
-
-
0029774363
-
Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae
-
Toke, D.A. and Martin, C.E. (1996) Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae. J. Biol. Chem. 271, 18413-18422
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 18413-18422
-
-
Toke, D.A.1
Martin, C.E.2
-
53
-
-
0030878240
-
ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation
-
Oh, CS., Toke, D.A., Mandala, S., and Martin, CE. (1997) ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation. J. Biol. Chem. 272, 17376-17384
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17376-17384
-
-
Oh, C.S.1
Toke, D.A.2
Mandala, S.3
Martin, C.E.4
-
54
-
-
0029079701
-
Characterization of a new gene family developing pleiotropic phenotypes upon mutation in Saccharomyces cerevisiae
-
Revardel, E., Bonneau, M., Durrens, P., and Aigle, M. (1995) Characterization of a new gene family developing pleiotropic phenotypes upon mutation in Saccharomyces cerevisiae. Biochim. Biophys. Acta 1263, 261-265
-
(1995)
Biochim. Biophys. Acta
, vol.1263
, pp. 261-265
-
-
Revardel, E.1
Bonneau, M.2
Durrens, P.3
Aigle, M.4
-
55
-
-
45549088118
-
Membrane topology and essential amino acid residues of Phs1, a 3-hydroxyacyl-CoA dehydratase involved in very long-chain fatty acid elongation
-
Kihara, A., Sakuraba, H., Ikeda, M., Denpoh, A., and Igarashi, Y. (2008) Membrane topology and essential amino acid residues of Phs1, a 3-hydroxyacyl-CoA dehydratase involved in very long-chain fatty acid elongation. J. Biol. Chem. 283, 11199-11209
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 11199-11209
-
-
Kihara, A.1
Sakuraba, H.2
Ikeda, M.3
Denpoh, A.4
Igarashi, Y.5
-
56
-
-
33750511727
-
A survey of essential gene function in the yeast cell division cycle
-
Yu, L., Pena Castillo, L., Mnaimneh, S., Hughes, T.R., and Brown, G.W. (2006) A survey of essential gene function in the yeast cell division cycle. Mol. Biol. Cell 17, 4736-4747
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 4736-4747
-
-
Yu, L.1
Pena Castillo, L.2
Mnaimneh, S.3
Hughes, T.R.4
Brown, G.W.5
-
57
-
-
0032583117
-
Involvement of long chain fatty acid elongation in the trafficking of secretory vesicles in yeast
-
David, D., Sundarababu, S., and Gerst, J.E. (1998) Involvement of long chain fatty acid elongation in the trafficking of secretory vesicles in yeast. J. Cell Biol. 143, 1167-1182
-
(1998)
J. Cell Biol.
, vol.143
, pp. 1167-1182
-
-
David, D.1
Sundarababu, S.2
Gerst, J.E.3
-
58
-
-
0029973561
-
A yeast acetyl coenzyme A carboxylase mutant links very-long-chain fatty acid synthesis to the structure and function of the nuclear membrane-pore complex
-
Schneiter, R., Hitomi, M., Ivessa, A.S., Fasch, E.V., Kohlwein, S.D., and Tartakoff, A.M. (1996) A yeast acetyl coenzyme A carboxylase mutant links very-long-chain fatty acid synthesis to the structure and function of the nuclear membrane-pore complex. Mol. Cell. Biol. 16, 7161-7172
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 7161-7172
-
-
Schneiter, R.1
Hitomi, M.2
Ivessa, A.S.3
Fasch, E.V.4
Kohlwein, S.D.5
Tartakoff, A.M.6
-
59
-
-
24344449583
-
Targeting of Tsc13p to nucleus-vacuole junctions: A role for very-long-chain fatty acids in the biogenesis of microautophagic vesicles
-
Kvam, E., Gable, K., Dunn, T.M., and Goldfarb, D.S. (2005) Targeting of Tsc13p to nucleus-vacuole junctions: a role for very-long-chain fatty acids in the biogenesis of microautophagic vesicles. Mol. Biol. Cell 16, 3987-3998
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 3987-3998
-
-
Kvam, E.1
Gable, K.2
Dunn, T.M.3
Goldfarb, D.S.4
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