Ectodomain movements of an ATP-gated ion channel (P2X2 receptor) probed by disulfide locking

Journal of Biological Chemistry

Volumn 289, Issue 14, 2014, Pages 9909-9917

  Stelmashenko, Olga ^a   Compan, Vincent ^b   Browne, Liam E ^b   North, R Alan ^a,b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; BIOPHYSICS; CELL MEMBRANES; COVALENT BONDS;

CHANNEL OPENING; DISULFIDE BONDS; HUMAN EMBRYONIC KIDNEY CELLS; ION PERMEATION; MEMBRANE BILAYERS; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANE HELICES; WESTERN BLOTTING;

DIMERS;

CYSTEINE; DITHIOTHREITOL; PURINERGIC P2X2 RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; CELL MEMBRANE; CELL STRAIN HEK293; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTALLOGRAPHY; DISULFIDE BOND; DISULFIDE LOCKING; HUMAN; HUMAN CELL; MOLECULAR PROBE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PURIFICATION; PROTEIN SUBUNIT; RAT; WESTERN BLOTTING;

ATP; DISULFIDE; ION CHANNELS; PURINERGIC RECEPTOR; RECEPTOR STRUCTURE-FUNCTION;

ADENOSINE TRIPHOSPHATE; AMINO ACID SUBSTITUTION; ANIMALS; CELL MEMBRANE; DISULFIDES; HUMANS; MUTATION, MISSENSE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, PURINERGIC P2X2;

EID: 84898063955     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.542811     Document Type: Article

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