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Volumn 33, Issue 14, 2014, Pages 1818-1827

RRP1B is a metastasis modifier that regulates the expression of alternative mRNA isoforms through interactions with SRSF1

Author keywords

Alternative splicing; Breast cancer; Germline modifiers; Metastasis; RNA seq; RRP1B

Indexed keywords

ONCOPROTEIN; RNA ISOFORM; SERINE ARGININE RICH SPLICING FACTOR 1; TRANSCRIPTOME; UNCLASSIFIED DRUG;

EID: 84898054240     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.133     Document Type: Article
Times cited : (18)

References (47)
  • 2
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • Ramaswamy S, Ross KN, Lander ES, Golub TR. A molecular signature of metastasis in primary solid tumors. Nat Genet 2003; 33: 49-54
    • (2003) Nat Genet , vol.33 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3    Golub, T.R.4
  • 4
    • 77449152122 scopus 로고    scopus 로고
    • Distinct inherited metastasis susceptibility exists for different breast cancer subtypes: A prognosis study
    • Hsieh SM, Look MP, Sieuwerts AM, Foekens JA, Hunter KW. Distinct inherited metastasis susceptibility exists for different breast cancer subtypes: A prognosis study. Breast Cancer Res 2009; 11: R75
    • (2009) Breast Cancer Res , vol.11
    • Hsieh, S.M.1    Look, M.P.2    Sieuwerts, A.M.3    Foekens, J.A.4    Hunter, K.W.5
  • 5
    • 70350381025 scopus 로고    scopus 로고
    • The metastasis efficiency modifier ribosomal rna processing 1 homolog b (rrp1b) is a chromatin-Associated factor
    • Crawford NP, Yang H, Mattaini KR, Hunter KW. The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-Associated factor. J Biol Chem 2009; 284: 28660-28673
    • (2009) J Biol Chem , vol.284 , pp. 28660-28673
    • Crawford, N.P.1    Yang, H.2    Mattaini, K.R.3    Hunter, K.W.4
  • 6
    • 78650095888 scopus 로고    scopus 로고
    • Rrp1b targets pp1 to mammalian cell nucleoli and is associated with pre-60s ribosomal subunits
    • Chamousset D, De Wever V, Moorhead GB, Chen Y, Boisvert FM, Lamond AI, et al. RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits. Mol Biol Cell 2010; 21: 4212-4226
    • (2010) Mol Biol Cell , vol.21 , pp. 4212-4226
    • Chamousset, D.1    De Wever, V.2    Moorhead, G.B.3    Chen, Y.4    Boisvert, F.M.5    Lamond, A.I.6
  • 7
    • 0027137934 scopus 로고
    • Specific interactions between proteins implicated in splice site selection and regulated alternative splicing
    • Wu JY, Maniatis T. Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell 1993; 75: 1061-1070
    • (1993) Cell , vol.75 , pp. 1061-1070
    • Wu, J.Y.1    Maniatis, T.2
  • 8
    • 0025367075 scopus 로고
    • The essential pre-mRNA splicing factor SF2 influences 5- splice site selection by activating proximal sites
    • Krainer AR, Conway GC, Kozak D. The essential pre-mRNA splicing factor SF2 influences 5- splice site selection by activating proximal sites. Cell 1990; 62: 35-42
    • (1990) Cell , vol.62 , pp. 35-42
    • Krainer, A.R.1    Conway, G.C.2    Kozak, D.3
  • 9
    • 0027494389 scopus 로고
    • Functional domains of the human splicing factor ASF/SF2
    • Zuo P, Manley JL. Functional domains of the human splicing factor ASF/SF2. EMBO J. 1993; 12: 4727-4737
    • (1993) EMBO J. , vol.12 , pp. 4727-4737
    • Zuo, P.1    Manley, J.L.2
  • 10
    • 34848855566 scopus 로고    scopus 로고
    • The u1 snrnp-Associated factor luc7p affects 5- splice site selection in yeast and human
    • Puig O, Bragado-Nilsson E, Koski T, Seraphin B. The U1 snRNP-Associated factor Luc7p affects 5- splice site selection in yeast and human. Nucleic Acids Res 2007; 35: 5874-5885
    • (2007) Nucleic Acids Res , vol.35 , pp. 5874-5885
    • Puig, O.1    Bragado-Nilsson, E.2    Koski, T.3    Seraphin, B.4
  • 11
    • 0037423730 scopus 로고    scopus 로고
    • Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein crop/luc7a
    • Umehara H, Nishii Y, Morishima M, Kakehi Y, Kioka N, Amachi T, et al. Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A. Biochem Biophys Res Commun 2003; 301: 324-329
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 324-329
    • Umehara, H.1    Nishii, Y.2    Morishima, M.3    Kakehi, Y.4    Kioka, N.5    Amachi, T.6
  • 12
    • 7444220147 scopus 로고    scopus 로고
    • Aberrant and alternative splicing in cancer
    • Venables JP. Aberrant and alternative splicing in cancer. Cancer Res 2004; 64: 7647-7654
    • (2004) Cancer Res , vol.64 , pp. 7647-7654
    • Venables, J.P.1
  • 13
    • 37349089805 scopus 로고    scopus 로고
    • Insights into the connection between cancer and alternative splicing
    • Kim E, Goren A, Ast G. Insights into the connection between cancer and alternative splicing. Trends Genet 2008; 24: 7-10
    • (2008) Trends Genet , vol.24 , pp. 7-10
    • Kim, E.1    Goren, A.2    Ast, G.3
  • 14
    • 0141974926 scopus 로고    scopus 로고
    • Discovery of novel splice forms and functional analysis of cancerspecific alternative splicing in human expressed sequences
    • Xu Q, Lee C. Discovery of novel splice forms and functional analysis of cancerspecific alternative splicing in human expressed sequences. Nucleic Acids Res 2003; 31: 5635-5643
    • (2003) Nucleic Acids Res , vol.31 , pp. 5635-5643
    • Xu, Q.1    Lee, C.2
  • 15
    • 0037310045 scopus 로고    scopus 로고
    • Computational analysis and experimental validation of tumor-Associated alternative RNA splicing in human cancer
    • Wang Z, Lo HS, Yang H, Gere S, Hu Y, Buetow KH, et al. Computational analysis and experimental validation of tumor-Associated alternative RNA splicing in human cancer. Cancer Res 2003; 63: 655-657
    • (2003) Cancer Res , vol.63 , pp. 655-657
    • Wang, Z.1    Lo, H.S.2    Yang, H.3    Gere, S.4    Hu, Y.5    Buetow, K.H.6
  • 16
    • 2442551589 scopus 로고    scopus 로고
    • Identification of alternatively spliced mRNA variants related to cancers by genome-wide ESTs alignment
    • Hui L, Zhang X, Wu X, Lin Z, Wang Q, Li Y, et al. Identification of alternatively spliced mRNA variants related to cancers by genome-wide ESTs alignment. Oncogene 2004; 23: 3013-3023
    • (2004) Oncogene , vol.23 , pp. 3013-3023
    • Hui, L.1    Zhang, X.2    Wu, X.3    Lin, Z.4    Wang, Q.5    Li, Y.6
  • 17
    • 34548758543 scopus 로고    scopus 로고
    • Splicing in disease: Disruption of the splicing code and the decoding machinery
    • Wang GS, Cooper TA. Splicing in disease: Disruption of the splicing code and the decoding machinery. Nat Rev Genet 2007; 8: 749-761
    • (2007) Nat Rev Genet , vol.8 , pp. 749-761
    • Wang, G.S.1    Cooper, T.A.2
  • 19
    • 78649289872 scopus 로고    scopus 로고
    • Global analysis of nascent RNA reveals transcriptional pausing in terminal exons
    • Carrillo Oesterreich F, Preibisch S, Neugebauer KM. Global analysis of nascent RNA reveals transcriptional pausing in terminal exons. Mol Cell 2010; 40: 571-581
    • (2010) Mol Cell , vol.40 , pp. 571-581
    • Carrillo Oesterreich, F.1    Preibisch, S.2    Neugebauer, K.M.3
  • 21
    • 79952266577 scopus 로고    scopus 로고
    • Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation
    • Ip JY, Schmidt D, Pan Q, Ramani AK, Fraser AG, Odom DT, et al. Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation. Genome Res 2011; 21: 390-401
    • (2011) Genome Res , vol.21 , pp. 390-401
    • Ip, J.Y.1    Schmidt, D.2    Pan, Q.3    Ramani, A.K.4    Fraser, A.G.5    Odom, D.T.6
  • 23
    • 81855183655 scopus 로고    scopus 로고
    • Singlemolecule imaging of transcriptionally coupled and uncoupled splicing
    • Vargas DY, Shah K, Batish M, Levandoski M, Sinha S, Marras SA, et al. Singlemolecule imaging of transcriptionally coupled and uncoupled splicing. Cell 2011; 147: 1054-1065
    • (2011) Cell , vol.147 , pp. 1054-1065
    • Vargas, D.Y.1    Shah, K.2    Batish, M.3    Levandoski, M.4    Sinha, S.5    Marras, S.A.6
  • 24
    • 77956968392 scopus 로고    scopus 로고
    • Halogen bonds form the basis for selective P-TEFb inhibition by DRB
    • Baumli S, Endicott JA, Johnson LN. Halogen bonds form the basis for selective P-TEFb inhibition by DRB. Chem Biol 2010; 17: 931-936
    • (2010) Chem Biol , vol.17 , pp. 931-936
    • Baumli, S.1    Endicott, J.A.2    Johnson, L.N.3
  • 25
    • 0023971164 scopus 로고
    • Stabilization of type I topoisomerase-DNA covalent complexes by actinomycin D
    • Trask DK, Muller MT. Stabilization of type I topoisomerase-DNA covalent complexes by actinomycin D. Proc Natl Acad Sci USA 1988; 85: 1417-1421
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1417-1421
    • Trask, D.K.1    Muller, M.T.2
  • 26
    • 79958701393 scopus 로고    scopus 로고
    • Inhibiting eukaryotic transcription: Which compound to choose How to evaluate its activity
    • Bensaude O. Inhibiting eukaryotic transcription: Which compound to choose? How to evaluate its activity? Transcription 2011; 2: 103-108
    • (2011) Transcription , vol.2 , pp. 103-108
    • Bensaude, O.1
  • 28
    • 0026503190 scopus 로고
    • Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor
    • Aslakson CJ, Miller FR. Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res 1992; 52: 1399-1405
    • (1992) Cancer Res , vol.52 , pp. 1399-1405
    • Aslakson, C.J.1    Miller, F.R.2
  • 29
    • 65449187606 scopus 로고    scopus 로고
    • SpliceAid: A database of experimental RNA target motifs bound by splicing proteins in humans
    • Piva F, Giulietti M, Nocchi L, Principato G. SpliceAid: A database of experimental RNA target motifs bound by splicing proteins in humans. Bioinformatics 2009; 25: 1211-1213
    • (2009) Bioinformatics , vol.25 , pp. 1211-1213
    • Piva, F.1    Giulietti, M.2    Nocchi, L.3    Principato, G.4
  • 30
    • 0029052435 scopus 로고
    • The G-rich auxiliary downstream element has distinct sequence and position requirements and mediates efficient 3- end pre-mRNA processing through a trans-Acting factor
    • Bagga PS, Ford LP, Chen F, Wilusz J. The G-rich auxiliary downstream element has distinct sequence and position requirements and mediates efficient 3- end pre-mRNA processing through a trans-Acting factor. Nucleic Acids Res 1995; 23: 1625-1631
    • (1995) Nucleic Acids Res , vol.23 , pp. 1625-1631
    • Bagga, P.S.1    Ford, L.P.2    Chen, F.3    Wilusz, J.4
  • 31
    • 0037089136 scopus 로고    scopus 로고
    • Downstream sequence elements with different affinities for the hnRNP H/H- protein influence the processing efficiency of mammalian polyadenylation signals
    • Arhin GK, Boots M, Bagga PS, Milcarek C, Wilusz J. Downstream sequence elements with different affinities for the hnRNP H/H- protein influence the processing efficiency of mammalian polyadenylation signals. Nucleic Acids Res 2002; 30: 1842-1850
    • (2002) Nucleic Acids Res , vol.30 , pp. 1842-1850
    • Arhin, G.K.1    Boots, M.2    Bagga, P.S.3    Milcarek, C.4    Wilusz, J.5
  • 32
    • 0032567539 scopus 로고    scopus 로고
    • Transcriptional upregulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals
    • Du K, Leu JI, Peng Y, Taub R. Transcriptional upregulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals. J Biol Chem 1998; 273: 35208-35215
    • (1998) J Biol Chem , vol.273 , pp. 35208-35215
    • Du, K.1    Leu, J.I.2    Peng, Y.3    Taub, R.4
  • 33
    • 0027160003 scopus 로고
    • Distinct functions of SR proteins in alternative pre-mRNA splicing
    • Zahler AM, Neugebauer KM, Lane WS, Roth MB. Distinct functions of SR proteins in alternative pre-mRNA splicing. Science 1993; 260: 219-222
    • (1993) Science , vol.260 , pp. 219-222
    • Zahler, A.M.1    Neugebauer, K.M.2    Lane, W.S.3    Roth, M.B.4
  • 34
    • 10944229314 scopus 로고    scopus 로고
    • Variation in alternative splicing across human tissues
    • Yeo G, Holste D, Kreiman G, Burge CB. Variation in alternative splicing across human tissues. Genome Biol 2004; 5: R74
    • (2004) Genome Biol , vol.5
    • Yeo, G.1    Holste, D.2    Kreiman, G.3    Burge, C.B.4
  • 35
    • 14544277546 scopus 로고    scopus 로고
    • Identification and analysis of alternative splicing events conserved in human and mouse
    • Yeo GW, Van Nostrand E, Holste D, Poggio T, Burge CB. Identification and analysis of alternative splicing events conserved in human and mouse. Proc Natl Acad Sci USA 2005; 102: 2850-2855
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2850-2855
    • Yeo, G.W.1    Van Nostrand, E.2    Holste, D.3    Poggio, T.4    Burge, C.B.5
  • 36
    • 33645218935 scopus 로고    scopus 로고
    • Alternative splicing increases complexity of stem cell transcriptome
    • Lemischka IR, Pritsker M. Alternative splicing increases complexity of stem cell transcriptome. Cell Cycle 2006; 5: 347-351
    • (2006) Cell Cycle , vol.5 , pp. 347-351
    • Lemischka, I.R.1    Pritsker, M.2
  • 37
    • 0037669010 scopus 로고    scopus 로고
    • Low conservation of alternative splicing patterns in the human and mouse genomes
    • Nurtdinov RN, Artamonova II, Mironov AA, Gelfand MS. Low conservation of alternative splicing patterns in the human and mouse genomes. Hum Mol Genet 2003; 12: 1313-1320
    • (2003) Hum Mol Genet , vol.12 , pp. 1313-1320
    • Nurtdinov, R.N.1    Artamonova, I.I.2    Mironov, A.A.3    Gelfand, M.S.4
  • 38
    • 33645833000 scopus 로고    scopus 로고
    • Unbalanced alternative splicing and its significance in cancer
    • Venables JP. Unbalanced alternative splicing and its significance in cancer. Bioessays 2006; 28: 378-386
    • (2006) Bioessays , vol.28 , pp. 378-386
    • Venables, J.P.1
  • 39
    • 38849124320 scopus 로고    scopus 로고
    • Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility
    • Lee JH, Horak CE, Khanna C, Meng Z, Yu LR, Veenstra TD, et al. Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility. Cancer Res 2008; 68: 639-644
    • (2008) Cancer Res , vol.68 , pp. 639-644
    • Lee, J.H.1    Horak, C.E.2    Khanna, C.3    Meng, Z.4    Yu, L.R.5    Veenstra, T.D.6
  • 40
    • 55549143293 scopus 로고    scopus 로고
    • The emerging role of splicing factors in cancer
    • Grosso AR, Martins S, Carmo-Fonseca M. The emerging role of splicing factors in cancer. EMBO Rep 2008; 9: 1087-1093
    • (2008) EMBO Rep , vol.9 , pp. 1087-1093
    • Grosso, A.R.1    Martins, S.2    Carmo-Fonseca, M.3
  • 41
  • 42
    • 84859245835 scopus 로고    scopus 로고
    • A quantitative, high-Throughput reverse genetic screen reveals novel connections between pre-mRNA splicing and 5- and 3- end transcript determinants
    • Albulescu LO, Sabet N, Gudipati M, Stepankiw N, Bergman ZJ, Huffaker TC, et al. A quantitative, high-Throughput reverse genetic screen reveals novel connections between pre-mRNA splicing and 5- and 3- end transcript determinants. PLoS Genet 2012; 8: E1002530
    • (2012) PLoS Genet , vol.8
    • Albulescu, L.O.1    Sabet, N.2    Gudipati, M.3    Stepankiw, N.4    Bergman, Z.J.5    Huffaker, T.C.6
  • 45
    • 65449136284 scopus 로고    scopus 로고
    • Tophat: Discovering splice junctions with rnaseq
    • Trapnell C, Pachter L, Salzberg SL. TopHat: Discovering splice junctions with RNASeq. Bioinformatics 2009; 25: 1105-1111
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 46
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • Trapnell C, Williams BA, Pertea G, Mortazavi A, Kwan G, van Baren MJ, et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 2010; 28: 511-515
    • (2010) Nat Biotechnol , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3    Mortazavi, A.4    Kwan, G.5    Van Baren, M.J.6


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