Downstream sequence elements with different affinities for the hnRNP H/H′ protein influence the processing efficiency of mammalian polyadenylation signals

Nucleic Acids Research

Volumn 30, Issue 8, 2002, Pages 1842-1850

  Arhin, George K ^a   Boots, Monika ^a   Bagga, Paramjeet S ^b   Milcarek, Christine ^c   Wilusz, Jeffrey ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b RAMAPO COLLEGE OF NEW JERSEY   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE; MESSENGER RNA PRECURSOR;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA ANALYSIS; RNA SEQUENCE; SIGNAL TRANSDUCTION;

ANIMALIA; MAMMALIA;

EID: 0037089136     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/30.8.1842     Document Type: Article

References (42)

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25. The G-rich auxiliary downstream element has distinct sequence and position requirements and mediates efficient 3′-end pre-mRNA processing through a trans-acting factor
26. DSEF-1 is a member of the hnRNP H family of RNA-binding proteins and stimulates pre-mRNA cleavage and polyadenylation in vitro
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33. + mRNA binding protein which interacts with a conserved G-rich element
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42. Cloning of human 2H9 heterogeneous nuclear ribonucleoproteins. Relation with splicing and early heat shock-induced splicing arrest