An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia

Nature Medicine

Volumn 20, Issue 4, 2014, Pages 398-407

  Dussiot, Michael ^a,b,c,d,e   Maciel, Thiago T ^a,b,c,d,e   Fricot, Aurélie ^a,b,c,d,e   Chartier, Céline ^a,b,c,d,e   Negre, Olivier ^f,g   Veiga, Joel ^d   Grapton, Damien ^a,b,c,d,e   Paubelle, Etienne ^a,b,c,d,e   Payen, Emmanuel ^f,g   Beuzard, Yves ^f,g   Leboulch, Philippe ^f,g   Ribeil, Jean Antoine ^a,b,c,d,h   Arlet, Jean Benoit ^a,b,c,d   Coté, Francine ^a,b,c,d   Courtois, Geneviève ^a,b,c,d   Ginzburg, Yelena Z ⁱ   Daniel, Thomas O ^j   Chopra, Rajesh ^j   Sung, Victoria ^k   Hermine, Olivier ^a,b,c,d,h   Moura, Ivan C ^a,b,c,d,e   more..

^a INSERM   (France)

^b PARIS DESCARTES SORBONNE PARIS CITÉ UNIVERSITY   (France)

^c CNRS   (France)

^d Laboratory of Excellence GR Ex   (France)

^e CENTRE DE RECHERCHE SUR L INFLAMMATION   (France)

^f INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^g Institute of Emerging Diseases and Innovative Therapies   (France)

^h HÔPITAL NECKER ENFANTS MALADES   (France)

ⁱ NEW YORK BLOOD CENTER   (United States)

^j CELGENE CORPORATION   (United States)

^k Celgene   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR 2; CYTOKINE; FAS LIGAND; GROWTH DIFFERENTIATION FACTOR; GROWTH DIFFERENTIATION FACTOR 11; GROWTH FACTOR; HEMOGLOBIN ALPHA CHAIN; LIGAND; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; BETA THALASSEMIA; CONTROLLED STUDY; ERYTHROBLAST; ERYTHROID CELL; ERYTHROPOIESIS; GENE AMPLIFICATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRECIPITATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SERUM;

MUS;

ACTIVIN RECEPTORS, TYPE II; ANIMALS; ANTIGENS, CD95; APOPTOSIS; AUTOCRINE COMMUNICATION; BETA-THALASSEMIA; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; ERYTHROBLASTS; ERYTHROPOIESIS; FAS LIGAND PROTEIN; GENE AMPLIFICATION; GROWTH DIFFERENTIATION FACTORS; HEMATINICS; LIGANDS; MICE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 84898049056     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3468     Document Type: Article

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