Pathophysiology of thalassemia

Current Opinion in Hematology

Volumn 9, Issue 2, 2002, Pages 123-126

  Schrier, Stanley L ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; BETA GLOBIN; CASPASE 3; CASPASE 7; CASPASE 8; FAS ANTIBODY; FAS LIGAND; HEMOGLOBIN E; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR GATA 1;

ALPHA THALASSEMIA; APOPTOSIS; BETA THALASSEMIA; DYSERYTHROPOIESIS; ERYTHROCYTE; ERYTHROID PRECURSOR CELL; HEMOLYSIS; HUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW;

APOPTOSIS; ERYTHROID PROGENITOR CELLS; ERYTHROPOIESIS; HEMOGLOBIN E; HEMOLYSIS; HUMANS; REACTIVE OXYGEN SPECIES; THALASSEMIA;

EID: 0036180342     PISSN: 10656251     EISSN: None     Source Type: Journal    
DOI: 10.1097/00062752-200203000-00007     Document Type: Review

References (25)

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3. Contribution of hemoglobin and membrane constituents modification to human erythrocyte damage promoted by peroxyl radicals of different charge and hydrophobicity
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5. Characterization and comparison of the RBC membrane damage in severe human alpha and beta thalassemia
6. Isolation, characterization, and immunoprecipitation studies of immune complexes from membranes of β-thalassemic erythrocytes
7. Lipid peroxidation and antioxidant status in beta-thalassemia
8. Membrane-bound iron contributes to oxidative damage of beta-thalassemia intermedia erythrocytes
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10. Cardiac involvement in thalassemia intermedia: A multicenter study
11. Introduction to the problem of hemoglobin E-beta thalassemia
12. Genetic factors affecting clinical severity in beta-thalassemia syndromes
13. Clinical manifestation of beta-thalassemia/hemoglobin E disease
14. Hemoglobin F and hemoglobin E/beta-thalassemia
15. A correlation of erythrokinetics, ineffective erythropoiesis, and erythroid precursor apoptosis in Thai patients with thalassemia
16. Iron overload and iron-chelating therapy in hemoglobin E-beta thalassemia
17. Accelerated programmed cell death (apoptosis) in erythroid precursors of patients with severe b-thalassemia (Cooley's anemia)
18. The importance of erythroid expansion in determining the extent of apoptosis in erythroid precursors in patients with beta-thalassemia major
19. Apoptotic role of Fas/Fas ligand in the regulation of erythropoiesis
20. Ineffective erythropoiesis in beta-thalassemia major is due to apoptosis at the polychromatophilic normoblast stage
21. Caspase activation: The induced proximity model
22. The biochemistry of apoptosis
23. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1
24. Caspase activation is required for terminal erythroid differentiation
25. The role of FAS and FAS ligand in the accelerated apoptosis of erythroid precursors in Cooley's anemia