-
1
-
-
72049089840
-
Cellular radiosensitivity: how much better do we understand it?
-
Jeggo P., Lavin M.F. Cellular radiosensitivity: how much better do we understand it?. Int J Radiat Biol 2009, 85:1061-1081.
-
(2009)
Int J Radiat Biol
, vol.85
, pp. 1061-1081
-
-
Jeggo, P.1
Lavin, M.F.2
-
2
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Ann Rev Biochem 2010, 79:181-211.
-
(2010)
Ann Rev Biochem
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
3
-
-
79956220705
-
Choosing the right path: does DNA-PK help make the decision?
-
Neal J.A., Meek K. Choosing the right path: does DNA-PK help make the decision?. Mutat Res 2011, 711:73-86.
-
(2011)
Mutat Res
, vol.711
, pp. 73-86
-
-
Neal, J.A.1
Meek, K.2
-
4
-
-
70350690563
-
Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase
-
Bernstein N.K., Hammel M., Mani R.S., et al. Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase. Nucleic Acids Res 2009, 37:6161-6173.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 6161-6173
-
-
Bernstein, N.K.1
Hammel, M.2
Mani, R.S.3
-
5
-
-
84873049469
-
Anoncatalytic function of the ligation complex during nonhomologous end joining
-
Cottarel J., Frit P., Bombarde O., et al. Anoncatalytic function of the ligation complex during nonhomologous end joining. JCell Biol 2013, 200:173-186.
-
(2013)
JCell Biol
, vol.200
, pp. 173-186
-
-
Cottarel, J.1
Frit, P.2
Bombarde, O.3
-
6
-
-
0035191378
-
Crystal structure of an Xrcc4-DNA ligase IV complex
-
Sibanda B.L., Critchlow S.E., Begun J., et al. Crystal structure of an Xrcc4-DNA ligase IV complex. Nat Struct Biol 2001, 8:1015-1019.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 1015-1019
-
-
Sibanda, B.L.1
Critchlow, S.E.2
Begun, J.3
-
7
-
-
38049034405
-
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ
-
Li Y., Chirgadze D.Y., Bolanos-Garcia V.M., et al. Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ. EMBO J 2008, 27:290-300.
-
(2008)
EMBO J
, vol.27
, pp. 290-300
-
-
Li, Y.1
Chirgadze, D.Y.2
Bolanos-Garcia, V.M.3
-
9
-
-
80755187806
-
Double-strand break end resection and repair pathway choice
-
Symington L.S., Gautier J. Double-strand break end resection and repair pathway choice. Ann Rev Genet 2011, 45:247-271.
-
(2011)
Ann Rev Genet
, vol.45
, pp. 247-271
-
-
Symington, L.S.1
Gautier, J.2
-
10
-
-
84865386136
-
BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair
-
Chapman J.R., Sossick A.J., Boulton S.J., Jackson S.P. BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair. JCell Sci 2012, 125:3529-3534.
-
(2012)
JCell Sci
, vol.125
, pp. 3529-3534
-
-
Chapman, J.R.1
Sossick, A.J.2
Boulton, S.J.3
Jackson, S.P.4
-
11
-
-
84890324730
-
Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection
-
Kakarougkas A., Ismail A., Katsuki Y., Freire R., Shibata A., Jeggo P.A. Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection. Nucleic Acids Res 2013, 41:10298-10311.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 10298-10311
-
-
Kakarougkas, A.1
Ismail, A.2
Katsuki, Y.3
Freire, R.4
Shibata, A.5
Jeggo, P.A.6
-
12
-
-
67749116521
-
The search for a human Holliday junction resolvase
-
West S.C. The search for a human Holliday junction resolvase. Biochem Soc Trans 2009, 37:519-526.
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 519-526
-
-
West, S.C.1
-
13
-
-
46249131123
-
Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
-
Bennardo N., Cheng A., Huang N., Stark J.M. Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet 2008, 4:e1000110.
-
(2008)
PLoS Genet
, vol.4
-
-
Bennardo, N.1
Cheng, A.2
Huang, N.3
Stark, J.M.4
-
14
-
-
84888626405
-
Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage
-
Deriano L., Roth D.B. Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage. Ann Rev Genet 2013, 47:433-455.
-
(2013)
Ann Rev Genet
, vol.47
, pp. 433-455
-
-
Deriano, L.1
Roth, D.B.2
-
15
-
-
67349246802
-
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
-
Yun M.H., Hiom K. CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. Nature 2009, 459:460-473.
-
(2009)
Nature
, vol.459
, pp. 460-473
-
-
Yun, M.H.1
Hiom, K.2
-
16
-
-
77957123627
-
Pathways of mammalian replication fork restart
-
Petermann E., Helleday T. Pathways of mammalian replication fork restart. Nat Rev Mol Cell Biol 2010, 11:683-687.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 683-687
-
-
Petermann, E.1
Helleday, T.2
-
17
-
-
70350763838
-
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
-
Beucher A., Birraux J., Tchouandong L., et al. ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2. EMBO J 2009, 28:3413-3427.
-
(2009)
EMBO J
, vol.28
, pp. 3413-3427
-
-
Beucher, A.1
Birraux, J.2
Tchouandong, L.3
-
18
-
-
79952762235
-
Factors determining DNA double-strand break repair pathway choice in G2 phase
-
Shibata A., Conrad S., Birraux J., et al. Factors determining DNA double-strand break repair pathway choice in G2 phase. EMBO J 2011, 30:1079-1092.
-
(2011)
EMBO J
, vol.30
, pp. 1079-1092
-
-
Shibata, A.1
Conrad, S.2
Birraux, J.3
-
19
-
-
63049101044
-
Regulatory ubiquitylation in response to DNA double-strand breaks
-
Panier S., Durocher D. Regulatory ubiquitylation in response to DNA double-strand breaks. DNA Repair 2009, 8:436-443.
-
(2009)
DNA Repair
, vol.8
, pp. 436-443
-
-
Panier, S.1
Durocher, D.2
-
20
-
-
78649450619
-
Assembly and function of DNA double-strand break repair foci in mammalian cells
-
Bekker-Jensen S., Mailand N. Assembly and function of DNA double-strand break repair foci in mammalian cells. DNA Repair 2010, 9:1212-1228.
-
(2010)
DNA Repair
, vol.9
, pp. 1212-1228
-
-
Bekker-Jensen, S.1
Mailand, N.2
-
21
-
-
84866388311
-
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
-
Mattiroli F., Vissers J.H., van Dijk W.J., et al. RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling. Cell 2012, 150:1182-1195.
-
(2012)
Cell
, vol.150
, pp. 1182-1195
-
-
Mattiroli, F.1
Vissers, J.H.2
van Dijk, W.J.3
-
22
-
-
33845666681
-
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
-
Botuyan M.V., Lee J., Ward I.M., et al. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 2006, 127:1361-1373.
-
(2006)
Cell
, vol.127
, pp. 1361-1373
-
-
Botuyan, M.V.1
Lee, J.2
Ward, I.M.3
-
23
-
-
84859895529
-
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
-
Mallette F.A., Mattiroli F., Cui G., et al. RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. EMBO J 2012, 31:1865-1878.
-
(2012)
EMBO J
, vol.31
, pp. 1865-1878
-
-
Mallette, F.A.1
Mattiroli, F.2
Cui, G.3
-
24
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
-
Bunting S.F., Callen E., Wong N., et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 2010, 141:243-254.
-
(2010)
Cell
, vol.141
, pp. 243-254
-
-
Bunting, S.F.1
Callen, E.2
Wong, N.3
-
25
-
-
77953291328
-
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
-
Bouwman P., Aly A., Escandell J.M., et al. 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. NSMB 2010, 17:688-695.
-
(2010)
NSMB
, vol.17
, pp. 688-695
-
-
Bouwman, P.1
Aly, A.2
Escandell, J.M.3
-
26
-
-
3242890575
-
Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time
-
Lukas J., Lukas C., Bartek J. Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time. DNA Repair 2004, 3:997-1007.
-
(2004)
DNA Repair
, vol.3
, pp. 997-1007
-
-
Lukas, J.1
Lukas, C.2
Bartek, J.3
-
27
-
-
79960812015
-
Understanding the limitations of radiation-induced cell cycle checkpoints
-
Deckbar D., Jeggo P.A., Lobrich M. Understanding the limitations of radiation-induced cell cycle checkpoints. Crit Rev Biochem Mol Biol 2011, 46:271-283.
-
(2011)
Crit Rev Biochem Mol Biol
, vol.46
, pp. 271-283
-
-
Deckbar, D.1
Jeggo, P.A.2
Lobrich, M.3
-
28
-
-
77953149691
-
The limitations of the G1-S checkpoint
-
Deckbar D., Stiff T., Koch B., Reis C., Lobrich M., Jeggo P.A. The limitations of the G1-S checkpoint. Cancer Res 2010, 70:4412-4421.
-
(2010)
Cancer Res
, vol.70
, pp. 4412-4421
-
-
Deckbar, D.1
Stiff, T.2
Koch, B.3
Reis, C.4
Lobrich, M.5
Jeggo, P.A.6
-
29
-
-
33947204449
-
Chromosome breakage after G2 checkpoint release
-
Deckbar D., Birraux J., Krempler A., et al. Chromosome breakage after G2 checkpoint release. JCell Biol 2007, 176:748-755.
-
(2007)
JCell Biol
, vol.176
, pp. 748-755
-
-
Deckbar, D.1
Birraux, J.2
Krempler, A.3
-
30
-
-
20644471358
-
Harmonising the response to DSBs: a new string in the ATM bow
-
Lobrich M., Jeggo P.A. Harmonising the response to DSBs: a new string in the ATM bow. DNA Repair 2005, 4:749-759.
-
(2005)
DNA Repair
, vol.4
, pp. 749-759
-
-
Lobrich, M.1
Jeggo, P.A.2
-
31
-
-
77953432695
-
Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest
-
Shibata A., Barton O., Noon A.T., et al. Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest. Mol Cell Biol 2010, 30:3371-3383.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 3371-3383
-
-
Shibata, A.1
Barton, O.2
Noon, A.T.3
-
32
-
-
0036903037
-
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1
-
Fernandez-Capetillo O., Chen H.T., Celeste A., et al. DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nat Cell Biol 2002, 4:993-997.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 993-997
-
-
Fernandez-Capetillo, O.1
Chen, H.T.2
Celeste, A.3
-
33
-
-
9744220428
-
Apathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci
-
Riballo E., Kuhne M., Rief N., et al. Apathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol Cell 2004, 16:715-724.
-
(2004)
Mol Cell
, vol.16
, pp. 715-724
-
-
Riballo, E.1
Kuhne, M.2
Rief, N.3
-
34
-
-
79960055393
-
KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response
-
Goodarzi A.A., Kurka T., Jeggo P.A. KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response. NSMB 2011, 18:831-839.
-
(2011)
NSMB
, vol.18
, pp. 831-839
-
-
Goodarzi, A.A.1
Kurka, T.2
Jeggo, P.A.3
-
35
-
-
28444433678
-
The two edges of the ATM sword: co-operation between repair and checkpoint functions
-
Lobrich M., Jeggo P.A. The two edges of the ATM sword: co-operation between repair and checkpoint functions. Radiother Oncol 2005, 76:112-128.
-
(2005)
Radiother Oncol
, vol.76
, pp. 112-128
-
-
Lobrich, M.1
Jeggo, P.A.2
-
36
-
-
61649093808
-
Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks
-
Shiotani B., Zou L. Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks. Mol Cell 2009, 33:547-558.
-
(2009)
Mol Cell
, vol.33
, pp. 547-558
-
-
Shiotani, B.1
Zou, L.2
-
37
-
-
78649707827
-
ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks
-
Bennardo N., Stark J.M. ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks. PLoS Genet 2010, 6:e1001194.
-
(2010)
PLoS Genet
, vol.6
-
-
Bennardo, N.1
Stark, J.M.2
-
38
-
-
84876877091
-
Acell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice
-
Escribano-Diaz C., Orthwein A., Fradet-Turcotte A., et al. Acell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice. Mol Cell 2013, 49:872-883.
-
(2013)
Mol Cell
, vol.49
, pp. 872-883
-
-
Escribano-Diaz, C.1
Orthwein, A.2
Fradet-Turcotte, A.3
-
39
-
-
79954528832
-
RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci
-
Hu Y., Scully R., Sobhian B., Xie A., Shestakova E., Livingston D.M. RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev 2011, 25:685-700.
-
(2011)
Genes Dev
, vol.25
, pp. 685-700
-
-
Hu, Y.1
Scully, R.2
Sobhian, B.3
Xie, A.4
Shestakova, E.5
Livingston, D.M.6
-
40
-
-
79953869356
-
The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection
-
Coleman K.A., Greenberg R.A. The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection. JBiol Chem 2011, 286:13669-13680.
-
(2011)
JBiol Chem
, vol.286
, pp. 13669-13680
-
-
Coleman, K.A.1
Greenberg, R.A.2
-
41
-
-
77953720192
-
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
-
Shanbhag N.M., Rafalska-Metcalf I.U., Balane-Bolivar C., Janicki S.M., Greenberg R.A. ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 2010, 141:970-981.
-
(2010)
Cell
, vol.141
, pp. 970-981
-
-
Shanbhag, N.M.1
Rafalska-Metcalf, I.U.2
Balane-Bolivar, C.3
Janicki, S.M.4
Greenberg, R.A.5
-
42
-
-
84862829622
-
DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks
-
Pankotai T., Bonhomme C., Chen D., Soutoglou E. DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks. NSMB 2012, 19:276-282.
-
(2012)
NSMB
, vol.19
, pp. 276-282
-
-
Pankotai, T.1
Bonhomme, C.2
Chen, D.3
Soutoglou, E.4
-
43
-
-
79959814259
-
DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation
-
Simsek D., Brunet E., Wong S.Y., et al. DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation. PLoS Genet 2011, 7:e1002080.
-
(2011)
PLoS Genet
, vol.7
-
-
Simsek, D.1
Brunet, E.2
Wong, S.Y.3
-
44
-
-
84876130803
-
Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic myeloid leukemias
-
Tobin L.A., Robert C., Rapoport A.P., et al. Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic myeloid leukemias. Oncogene 2012, 32:1784-1793.
-
(2012)
Oncogene
, vol.32
, pp. 1784-1793
-
-
Tobin, L.A.1
Robert, C.2
Rapoport, A.P.3
-
45
-
-
5144225797
-
DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining
-
Bentley J., Diggle C.P., Harnden P., Knowles M.A., Kiltie A.E. DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining. Nucleic Acids Res 2004, 32:5249-5259.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 5249-5259
-
-
Bentley, J.1
Diggle, C.P.2
Harnden, P.3
Knowles, M.A.4
Kiltie, A.E.5
|