Albumin fusion prolongs the antioxidant and anti-inflammatory activities of thioredoxin in mice with acetaminophen-induced hepatitis

Molecular Pharmaceutics

Volumn 11, Issue 4, 2014, Pages 1228-1238

  Tanaka, Ryota ^a   Ishima, Yu ^a   Maeda, Hitoshi ^a   Kodama, Azusa ^a   Nagao, Saori ^a   Watanabe, Hiroshi ^a   Chuang, Victor Tuan Giam ^b   Otagiri, Masaki ^c   Maruyama, Toru ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b CURTIN UNIVERSITY   (Australia)

^c SOJO UNIVERSITY   (Japan)

Author keywords

acetaminophen; drug delivery system; inflammation; oxidative stress; recombinant protein

Indexed keywords

ALBUMIN; AMINOTRANSFERASE; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CHEMOKINE; CYTOKINE; LINSIDOMINE; PARACETAMOL; RECOMBINANT HUMAN SERUM ALBUMIN; RECOMBINANT HUMAN SERUM ALBUMIN THIOREDOXIN 1; THIOREDOXIN 1; UNCLASSIFIED DRUG; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; SERUM ALBUMIN;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL COUNT; CONTROLLED STUDY; HEPATITIS; HISTOPATHOLOGY; IN VITRO STUDY; INFLAMMATION; LETHAL DOSE; LIVER CELL; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NITRATIVE STRESS; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SURVIVAL RATE; ANIMAL; BLOOD; C57BL MOUSE; DRUG-INDUCED LIVER INJURY; HEPG2 CELL LINE; HUMAN; METABOLISM; TOXICITY;

ACETAMINOPHEN; ALANINE TRANSAMINASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; CYTOKINES; DRUG-INDUCED LIVER INJURY; HEP G2 CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; SERUM ALBUMIN;

EID: 84898018008     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400690v     Document Type: Article

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