Hydrogel-forming microneedles increase in volume during swelling in skin, but skin barrier function recovery is unaffected

Journal of Pharmaceutical Sciences

Volumn 103, Issue 5, 2014, Pages 1478-1486

  Donnelly, Ryan F ^a   Mooney, Karen ^a   McCrudden, Maelíosa T C ^a   Vicente Pérez, Eva M ^a   Belaid, Luc ^a   González Vázquez, Patricia ^a   McElnay, James C ^a   Woolfson, A David ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

diffusion; hydrogel; microneedle; micropore; OCT; percutaneous; skin; skin barrier; transdermal

Indexed keywords

GANTREZ COPOLYMER; MACROGOL; HYDROGEL; POLYMER;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY DEVICE; DRUG DELIVERY SYSTEM; ERYTHEMA; FEMALE; FOLLOW UP; HUMAN; HUMAN EXPERIMENT; HYDROGEL; INTERSTITIAL FLUID; MALE; MASS; MICRONEEDLE; MIDDLE AGED; NORMAL HUMAN; OPTICAL COHERENCE TOMOGRAPHY; PAIN ASSESSMENT; SKIN SWELLING; SKIN WATER LOSS; ADMINISTRATION AND DOSAGE; CHEMISTRY; CONVALESCENCE; DEVICES; DRUG EFFECTS; EQUIPMENT DESIGN; INTRADERMAL DRUG ADMINISTRATION; MICROINJECTION; NEEDLE; PROCEDURES; SKIN; YOUNG ADULT;

ADMINISTRATION, CUTANEOUS; ADULT; EQUIPMENT DESIGN; FEMALE; HUMANS; HYDROGEL; MALE; MICROINJECTIONS; MIDDLE AGED; NEEDLES; POLYMERS; RECOVERY OF FUNCTION; SKIN; YOUNG ADULT;

EID: 84898006550     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23921     Document Type: Article

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