Optical coherence tomography is a valuable tool in the study of the effects of microneedle geometry on skin penetration characteristics and in-skin dissolution

Journal of Controlled Release

Volumn 147, Issue 3, 2010, Pages 333-341

  Donnelly, Ryan F ^a   Garland, Martin J ^a   Morrow, Desmond I J ^a   Migalska, Katarzyna ^a   Singh, Thakur Raghu Raj ^a   Majithiya, Rita ^a   Woolfson, A David ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Optical coherence tomography; Polymeric microneedle arrays

Indexed keywords

COMMERCIAL EXPLOITATION; CUMULATIVE AMOUNT; DRUG DELIVERY SYSTEM; DRUG PERMEATION; IN-VITRO; MICRONEEDLE ARRAYS; MICRONEEDLES; OPTICAL COHERENCE TOMOGRAPHY; PENETRATION CHARACTERISTIC; PORCINE SKIN; SKIN MODEL; SKIN PENETRATION; SOLUBLE MN;

COMPUTATIONAL GEOMETRY; DISSOLUTION; DRUG DELIVERY; DRUG PRODUCTS; MALEIC ANHYDRIDE; NEEDLES; PEDIATRICS; TOMOGRAPHY;

POLYMERS;

MALEIC ANHYDRIDE; POLY(METHYLVINYLETHER CO MALEIC ANHYDRIDE); THEOPHYLLINE; UNCLASSIFIED DRUG;

ARTICLE; DISSOLUTION; DRUG DELIVERY SYSTEM; IN VITRO STUDY; MEDICAL INSTRUMENTATION; MICROARRAY ANALYSIS; MICRONEEDLE ARRAY; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; SKIN PENETRATION; SKINFOLD THICKNESS; SWINE;

ANIMALS; ANIMALS, NEWBORN; DIFFUSION; DRUG CARRIERS; EQUIPMENT DESIGN; INJECTIONS, INTRADERMAL; MALEATES; MICROINJECTIONS; MINIATURIZATION; NEEDLES; PERMEABILITY; POLYETHYLENES; SKIN; SKIN ABSORPTION; SOLUBILITY; SWINE; THEOPHYLLINE; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 78049472743     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.08.008     Document Type: Article

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