A CD40/CD40L feedback loop drives the breakdown of CD8+ T-cell tolerance following depletion of suppressive CD4+ T cells

European Journal of Immunology

Volumn 44, Issue 4, 2014, Pages 1099-1107

  Muth, Sabine ^a,b   Schütze, Kristian ^a,b   Hain, Tobias ^a,b   Yagita, Hideo ^c   Schild, Hansjörg ^a,b   Probst, Hans Christian ^a,b  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b Research Center for Immunology (FZI)   (Germany)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CD40 ligation; Dendritic cells; Peripheral tolerance

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNODEFICIENCY; CONTROLLED STUDY; CROSS PRESENTATION; DENDRITIC CELL; FEEDBACK SYSTEM; IMMUNOLOGICAL TOLERANCE; IMMUNOREACTIVITY; IMMUNOSTIMULATION; LIGATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION;

CD40 LIGATION; CD8+ T CELLS; DENDRITIC CELLS; PERIPHERAL TOLERANCE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN PRESENTATION; ANTIGENS, CD40; BONE MARROW TRANSPLANTATION; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; DENDRITIC CELLS; FEEDBACK, PHYSIOLOGICAL; FLOW CYTOMETRY; IMMUNE TOLERANCE; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; T-LYMPHOCYTES, CYTOTOXIC; TRANSPLANTATION CHIMERA;

EID: 84897971007     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343738     Document Type: Article

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