A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin-dependent diabetes mellitus in the non-obese diabetic mouse

International Immunology

Volumn 15, Issue 3, 2003, Pages 351-357

  Eshima, Koji ^a,e   Mora, Conchi ^a,f   Wong, F Susan ^b   Green, E Allison ^c   Grewal, Iqbal S ^d   Flavell, Richard A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d GENENTECH INC   (United States)

^e KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Antigen presenting cell; CD4 T lymphocyte; CD40; Insulitis

Indexed keywords

B7 ANTIGEN; CD4 ANTIGEN; CD40 LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DISEASE COURSE; GENE EXPRESSION; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; LYMPHOCYTE FUNCTION; MOUSE; MOUSE STRAIN; NONHUMAN; OBESITY; OBSERVATION; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; T LYMPHOCYTE; TIME; TRANSGENE;

ANIMALS; ANTIGENS, CD80; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; DIABETES MELLITUS, TYPE 1; GENOTYPE; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; PHENOTYPE;

EID: 0037343158     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxg035     Document Type: Article

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