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Volumn 9, Issue 1, 2014, Pages

Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN REGION; CELL DISRUPTION; CONTROLLED STUDY; DENDRITIC SPINE; DENTATE GYRUS; ELECTRON MICROSCOPY; FEMALE; FILOPODIUM; HIPPOCAMPAL CA3 REGION; HIPPOCAMPAL MOSSY FIBER; MOUSE; MOUSE MODEL; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; POSTSYNAPTIC POTENTIAL; PRESYNAPTIC NERVE; SYNAPSE; SYNAPTIC TRANSMISSION; SYNAPTOSOME;

EID: 84897969776     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084349     Document Type: Article
Times cited : (26)

References (49)
  • 1
    • 0001181116 scopus 로고    scopus 로고
    • Alzheimer's Disease: Molecular Understanding Predicts Amyloid-Based Therapeutics
    • DOI 10.1146/annurev.pharmtox.43.100901.140248
    • Selkoe DJ, Schenk D (2003) Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics. Annu Rev Pharmacol Toxicol 43: 545-584. (Pubitemid 37372653)
    • (2003) Annual Review of Pharmacology and Toxicology , vol.43 , pp. 545-584
    • Selkoe, D.J.1    Schenk, D.2
  • 2
    • 33746310315 scopus 로고    scopus 로고
    • Alzheimer's disease
    • DOI 10.1016/S0140-6736(06)69113-7, PII S0140673606691137
    • Blennow K, de Leon MJ, Zetterberg H (2006) Alzheimer's disease. Lancet 368: 387-403. (Pubitemid 44108123)
    • (2006) Lancet , vol.368 , Issue.9533 , pp. 387-403
    • Blennow, K.1    De Leon, M.J.2    Zetterberg, H.3
  • 3
    • 0025269152 scopus 로고
    • Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity
    • DeKosky ST, Scheff SW (1990) Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity. Ann Neurol 27: 457-464. (Pubitemid 20149963)
    • (1990) Annals of Neurology , vol.27 , Issue.5 , pp. 457-464
    • DeKosky, S.T.1    Scheff, S.W.2
  • 4
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
    • Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, et al. (1991) Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30: 572-580.
    • (1991) Ann Neurol , vol.30 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3    Butters, N.4    DeTeresa, R.5
  • 9
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe DJ (2002) Alzheimer's disease is a synaptic failure. Science 298: 789-791.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 11
    • 33845411954 scopus 로고    scopus 로고
    • AMPAR Removal Underlies Abeta-Induced Synaptic Depression and Dendritic Spine Loss
    • DOI 10.1016/j.neuron.2006.10.035, PII S0896627306008725
    • Hsieh H, Boehm J, Sato C, Iwatsubo T, Tomita T, et al. (2006) AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 52: 831-843. (Pubitemid 44828454)
    • (2006) Neuron , vol.52 , Issue.5 , pp. 831-843
    • Hsieh, H.1    Boehm, J.2    Sato, C.3    Iwatsubo, T.4    Tomita, T.5    Sisodia, S.6    Malinow, R.7
  • 13
    • 0043095312 scopus 로고    scopus 로고
    • Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype
    • DOI 10.1016/S0969-9961(03)00079-2
    • Lanz TA, Carter DB, Merchant KM (2003) Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype. Neurobiol Dis 13: 246-253. (Pubitemid 36937206)
    • (2003) Neurobiology of Disease , vol.13 , Issue.3 , pp. 246-253
    • Lanz, T.A.1    Carter, D.B.2    Merchant, K.M.3
  • 14
    • 23444448170 scopus 로고    scopus 로고
    • Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy
    • DOI 10.1523/JNEUROSCI.1879-05.2005
    • Spires TL, Meyer-Luehmann M, Stern EA, McLean PJ, Skoch J, et al. (2005) Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy. J Neurosci 25: 7278-7287. (Pubitemid 41113944)
    • (2005) Journal of Neuroscience , vol.25 , Issue.31 , pp. 7278-7287
    • Spires, T.L.1    Meyer-Luehmann, M.2    Stern, E.A.3    McLean, P.J.4    Skoch, J.5    Nguyen, P.T.6    Bacskai, B.J.7    Hyman, B.T.8
  • 15
  • 16
    • 34548446723 scopus 로고    scopus 로고
    • Spatial cognition and the human navigation network in AD and MCI
    • DOI 10.1212/01.wnl.0000271376.19515.c6, PII 0000611420070904000010
    • DeIpolyi AR, Rankin KP, Mucke L, Miller BL, Gorno-Tempini ML (2007) Spatial cognition and the human navigation network in AD and MCI. Neurology 69: 986-997. (Pubitemid 47366052)
    • (2007) Neurology , vol.69 , Issue.10 , pp. 986-997
    • DeIpolyi, A.R.1    Rankin, K.P.2    Mucke, L.3    Miller, B.L.4    Gorno-Tempini, M.L.5
  • 17
    • 62649116385 scopus 로고    scopus 로고
    • Cognitive map in patients with mild Alzheimer's disease: A computer-generated arena study
    • Jheng SS, Pai MC (2009) Cognitive map in patients with mild Alzheimer's disease: a computer-generated arena study. Behav Brain Res 200: 42-47.
    • (2009) Behav Brain Res , vol.200 , pp. 42-47
    • Jheng, S.S.1    Pai, M.C.2
  • 18
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
    • DOI 10.1126/science.274.5284.99
    • Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, et al. (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274: 99-102. (Pubitemid 26332733)
    • (1996) Science , vol.274 , Issue.5284 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3    Eckman, C.4    Harigaya, Y.5    Younkin, S.6    Yang, F.7    Cole, G.8
  • 20
    • 33645038471 scopus 로고    scopus 로고
    • A specific amyloid-beta protein assembly in the brain impairs memory
    • Lesne S, Koh MT, Kotilinek L, Kayed R, Glabe CG, et al. (2006) A specific amyloid-beta protein assembly in the brain impairs memory. Nature 440: 352-357.
    • (2006) Nature , vol.440 , pp. 352-357
    • Lesne, S.1    Koh, M.T.2    Kotilinek, L.3    Kayed, R.4    Glabe, C.G.5
  • 21
    • 33748651454 scopus 로고    scopus 로고
    • Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network
    • DOI 10.1007/s00424-006-0093-2, 25 Years of Giga-Seal Patch Clamping
    • Bischofberger J, Engel D, Frotscher M, Jonas P (2006) Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network. Pflugers Arch 453: 361-372. (Pubitemid 44764237)
    • (2006) Pflugers Archiv European Journal of Physiology , vol.453 , Issue.3 , pp. 361-372
    • Bischofberger, J.1    Engel, D.2    Frotscher, M.3    Jonas, P.4
  • 22
    • 33847149696 scopus 로고    scopus 로고
    • Pattern separation in the dentate gyrus and CA3 of the hippocampus
    • DOI 10.1126/science.1135801
    • Leutgeb JK, Leutgeb S, Moser MB, Moser EI (2007) Pattern separation in the dentate gyrus and CA3 of the hippocampus. Science 315: 961-966. (Pubitemid 46281178)
    • (2007) Science , vol.315 , Issue.5814 , pp. 961-966
    • Leutgeb, J.K.1    Leutgeb, S.2    Moser, M.-B.3    Moser, E.I.4
  • 23
    • 27644593831 scopus 로고    scopus 로고
    • Synaptic plasticity at hippocampal mossy fibre synapses
    • DOI 10.1038/nrn1786, PII N1786
    • Nicoll RA, Schmitz D (2005) Synaptic plasticity at hippocampal mossy fibre synapses. Nat Rev Neurosci 6: 863-876. (Pubitemid 41568728)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.11 , pp. 863-876
    • Nicoll, R.A.1    Schmitz, D.2
  • 24
    • 79955482986 scopus 로고    scopus 로고
    • Evidence for functional specialization of hippocampal subfields detected by MR subfield volumetry on high resolution images at 4 T
    • Mueller SG, Chao LL, Berman B, Weiner MW (2011) Evidence for functional specialization of hippocampal subfields detected by MR subfield volumetry on high resolution images at 4 T. Neuroimage 56: 851-857.
    • (2011) Neuroimage , vol.56 , pp. 851-857
    • Mueller, S.G.1    Chao, L.L.2    Berman, B.3    Weiner, M.W.4
  • 25
    • 77956277498 scopus 로고    scopus 로고
    • Hippocampal atrophy patterns in mild cognitive impairment and Alzheimer's disease
    • Mueller SG, Schuff N, Yaffe K, Madison C, Miller B, et al. (2010) Hippocampal atrophy patterns in mild cognitive impairment and Alzheimer's disease. Hum Brain Mapp 31: 1339-1347.
    • (2010) Hum Brain Mapp , vol.31 , pp. 1339-1347
    • Mueller, S.G.1    Schuff, N.2    Yaffe, K.3    Madison, C.4    Miller, B.5
  • 26
    • 80051937468 scopus 로고    scopus 로고
    • Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults
    • Yassa MA, Lacy JW, Stark SM, Albert MS, Gallagher M, et al. (2011) Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults. Hippocampus 21: 968-979.
    • (2011) Hippocampus , vol.21 , pp. 968-979
    • Yassa, M.A.1    Lacy, J.W.2    Stark, S.M.3    Albert, M.S.4    Gallagher, M.5
  • 27
    • 77952422876 scopus 로고    scopus 로고
    • High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic Mild Cognitive Impairment
    • Yassa MA, Stark SM, Bakker A, Albert MS, Gallagher M, et al. (2010) High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic Mild Cognitive Impairment. Neuroimage 51: 1242-1252.
    • (2010) Neuroimage , vol.51 , pp. 1242-1252
    • Yassa, M.A.1    Stark, S.M.2    Bakker, A.3    Albert, M.S.4    Gallagher, M.5
  • 28
    • 79960874601 scopus 로고    scopus 로고
    • Hippocampal synaptic activity, pattern separation and episodic-like memory: Implications for mouse models of Alzheimer's disease pathology
    • Palmer A, Good M (2011) Hippocampal synaptic activity, pattern separation and episodic-like memory: implications for mouse models of Alzheimer's disease pathology. Biochem Soc Trans 39: 902-909.
    • (2011) Biochem Soc Trans , vol.39 , pp. 902-909
    • Palmer, A.1    Good, M.2
  • 29
    • 0036089430 scopus 로고    scopus 로고
    • Giant miniature EPSCs at the hippocampal mossy fiber to CA3 pyramidal cell synapse are monoquantal
    • Henze DA, McMahon DB, Harris KM, Barrionuevo G (2002) Giant miniature EPSCs at the hippocampal mossy fiber to CA3 pyramidal cell synapse are monoquantal. J Neurophysiol 87: 15-29. (Pubitemid 34669926)
    • (2002) Journal of Neurophysiology , vol.87 , Issue.1 , pp. 15-29
    • Henze, D.A.1    Mcmahon, D.B.T.2    Harris, K.M.3    Barrionuevo, G.4
  • 30
    • 0036326542 scopus 로고    scopus 로고
    • Single granule cells reliably discharge targets in the hippocampal CA3 network in vivo
    • DOI 10.1038/nn887
    • Henze DA, Wittner L, Buzsaki G (2002) Single granule cells reliably discharge targets in the hippocampal CA3 network in vivo. Nat Neurosci 5: 790-795. (Pubitemid 34827598)
    • (2002) Nature Neuroscience , vol.5 , Issue.8 , pp. 790-795
    • Henze, D.A.1    Wittner, L.2    Buzsaki, G.3
  • 32
    • 84872092707 scopus 로고    scopus 로고
    • Deconstructing complexity: Serial block-face electron microscopic analysis of the hippocampal mossy fiber synapse
    • Wilke SA, Antonios JK, Bushong EA, Badkoobehi A, Malek E, et al. (2013) Deconstructing complexity: serial block-face electron microscopic analysis of the hippocampal mossy fiber synapse. J Neurosci 33: 507-522.
    • (2013) J Neurosci , vol.33 , pp. 507-522
    • Wilke, S.A.1    Antonios, J.K.2    Bushong, E.A.3    Badkoobehi, A.4    Malek, E.5
  • 33
    • 0041709922 scopus 로고    scopus 로고
    • GABAergic cells are the major postsynaptic targets of mossy fibers in the rat hippocampus
    • Acsady L, Kamondi A, Sik A, Freund T, Buzsaki G (1998) GABAergic cells are the major postsynaptic targets of mossy fibers in the rat hippocampus. J Neurosci 18: 3386-3403. (Pubitemid 28186030)
    • (1998) Journal of Neuroscience , vol.18 , Issue.9 , pp. 3386-3403
    • Acsady, L.1    Kamondi, A.2    Sik, A.3    Freund, T.4    Buzsaki, G.5
  • 35
    • 0026778684 scopus 로고
    • Three-dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus
    • Chicurel ME, Harris KM (1992) Three-dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus. J Comp Neurol 325: 169-182.
    • (1992) J Comp Neurol , vol.325 , pp. 169-182
    • Chicurel, M.E.1    Harris, K.M.2
  • 36
    • 0242380300 scopus 로고    scopus 로고
    • Interneuron Diversity series: Containing the detonation - Feedforward inhibition in the CA3 hippocampus
    • DOI 10.1016/j.tins.2003.09.007
    • Lawrence JJ, McBain CJ (2003) Interneuron diversity series: containing the detonation-feedforward inhibition in the CA3 hippocampus. Trends Neurosci 26: 631-640. (Pubitemid 37338372)
    • (2003) Trends in Neurosciences , vol.26 , Issue.11 , pp. 631-640
    • Lawrence, J.J.1    McBain, C.J.2
  • 37
    • 4644349968 scopus 로고    scopus 로고
    • A frequency-dependent switch from inhibition to excitation in a hippocampal unitary circuit
    • DOI 10.1038/nature02854
    • Mori M, Abegg MH, Gahwiler BH, Gerber U (2004) A frequency-dependent switch from inhibition to excitation in a hippocampal unitary circuit. Nature 431: 453-456. (Pubitemid 39329584)
    • (2004) Nature , vol.431 , Issue.7007 , pp. 453-456
    • Morl, M.1    Abegg, M.H.2    Gahwiler, B.H.3    Gerber, U.4
  • 38
    • 33749050824 scopus 로고    scopus 로고
    • Towards neural circuit reconstruction with volume electron microscopy techniques
    • DOI 10.1016/j.conb.2006.08.010, PII S0959438806001140, Neuronal and Glial Cell Biology / New Technologies
    • Briggman KL, Denk W (2006) Towards neural circuit reconstruction with volume electron microscopy techniques. Curr Opin Neurobiol 16: 562-570. (Pubitemid 44466398)
    • (2006) Current Opinion in Neurobiology , vol.16 , Issue.5 , pp. 562-570
    • Briggman, K.L.1    Denk, W.2
  • 39
    • 14044262855 scopus 로고    scopus 로고
    • Serial block-face scanning electron microscopy to reconstruct three-dimensional tissue nanostructure
    • Denk W, Horstmann H (2004) Serial block-face scanning electron microscopy to reconstruct three-dimensional tissue nanostructure. PLoS Biol 2: e329.
    • (2004) PLoS Biol , vol.2
    • Denk, W.1    Horstmann, H.2
  • 42
    • 0032167980 scopus 로고    scopus 로고
    • Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus
    • DOI 10.1016/S0896-6273(00)80565-6
    • Nusser Z, Lujan R, Laube G, Roberts JD, Molnar E, et al. (1998) Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus. Neuron 21: 545-559. (Pubitemid 28475506)
    • (1998) Neuron , vol.21 , Issue.3 , pp. 545-559
    • Nusser, Z.1    Lujan, R.2    Laube, G.3    Roberts, J.D.B.4    Molnar, E.5    Somogyi, P.6
  • 43
    • 0033588814 scopus 로고    scopus 로고
    • Immunogold localization of AMPA and NMDA receptors in somatic sensory cortex of albino rat
    • DOI 10.1002/(SICI)1096-9861(19990920)412:2<292::AI
    • Kharazia VN, Weinberg RJ (1999) Immunogold localization of AMPA and NMDA receptors in somatic sensory cortex of albino rat. J Comp Neurol 412: 292-302. (Pubitemid 29395366)
    • (1999) Journal of Comparative Neurology , vol.412 , Issue.2 , pp. 292-302
    • Kharazia, V.N.1    Weinberg, R.J.2
  • 44
    • 0342375000 scopus 로고    scopus 로고
    • Different modes of expression of AMPA and NMDA receptors in hippocampal synapses
    • DOI 10.1038/10172
    • Takumi Y, Ramirez-Leon V, Laake P, Rinvik E, Ottersen OP (1999) Different modes of expression of AMPA and NMDA receptors in hippocampal synapses. Nat Neurosci 2: 618-624. (Pubitemid 30491212)
    • (1999) Nature Neuroscience , vol.2 , Issue.7 , pp. 618-624
    • Takumi, Y.1    Ramirez-Leon, V.2    Laake, P.3    Rinvik, E.4    Ottersen, O.P.5
  • 45
    • 79957622225 scopus 로고    scopus 로고
    • Learning-related feedforward inhibitory connectivity growth required for memory precision
    • Ruediger S, Vittori C, Bednarek E, Genoud C, Strata P, et al. (2011) Learning-related feedforward inhibitory connectivity growth required for memory precision. Nature 473: 514-518.
    • (2011) Nature , vol.473 , pp. 514-518
    • Ruediger, S.1    Vittori, C.2    Bednarek, E.3    Genoud, C.4    Strata, P.5
  • 46
    • 77954814641 scopus 로고    scopus 로고
    • A computational theory of episodic memory formation in the hippocampus
    • Rolls ET (2010) A computational theory of episodic memory formation in the hippocampus. Behav Brain Res 215: 180-196.
    • (2010) Behav Brain Res , vol.215 , pp. 180-196
    • Rolls, E.T.1
  • 47
    • 36448971571 scopus 로고    scopus 로고
    • Pattern separation, pattern completion, and new neuronal codes within a continuous CA3 map
    • DOI 10.1101/lm.703907
    • Leutgeb S, Leutgeb JK (2007) Pattern separation, pattern completion, and new neuronal codes within a continuous CA3 map. Learn Mem 14: 745-757. (Pubitemid 350172773)
    • (2007) Learning and Memory , vol.14 , Issue.11 , pp. 745-757
    • Leutgeb, S.1    Leutgeb, J.K.2
  • 48
    • 0345276568 scopus 로고    scopus 로고
    • Synaptic pathology in Alzheimer's disease: A review of ultrastructural studies
    • DOI 10.1016/j.neurobiolaging.2003.08.002
    • Scheff SW, Price DA (2003) Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies. Neurobiol Aging 24: 1029-1046. (Pubitemid 37487881)
    • (2003) Neurobiology of Aging , vol.24 , Issue.8 , pp. 1029-1046
    • Scheff, S.W.1    Price, D.A.2
  • 49
    • 0029879295 scopus 로고    scopus 로고
    • Computer visualization of three-dimensional image data using IMOD
    • DOI 10.1006/jsbi.1996.0013
    • Kremer JR, Mastronarde DN, McIntosh JR (1996) Computer visualization of three-dimensional image data using IMOD. J Struct Biol 116: 71-76. (Pubitemid 26093126)
    • (1996) Journal of Structural Biology , vol.116 , Issue.1 , pp. 71-76
    • Kremer, J.R.1    Mastronarde, D.N.2    McIntosh, J.R.3


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