Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability

Genes, Brain and Behavior

Volumn 13, Issue 4, 2014, Pages 394-408

  Speca, D J ^a   Ogata, G ^a   Mandikian, D ^a   Bishop, H I ^a   Wiler, S W ^a   Eum, K ^b   Wenzel, H Jürgen ^b   Doisy, E T ^b   Matt, L ^b   Campi, K L ^a   Golub, M S ^a   Nerbonne, J M ^c   Hell, J W ^b   Trainor, B C ^a   Sack, J T ^b   Schwartzkroin, P A ^b   Trimmer, J S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hyperactivity; Kcnb1; Long term potentiation; Seizure

Indexed keywords

BICUCULLINE; DELAYED RECTIFIER POTASSIUM CHANNEL; DELAYED RECTIFIER POTASSIUM CHANNEL KV2.1; FLUROTHYL; PILOCARPINE; UNCLASSIFIED DRUG; CONVULSANT AGENT; KCNB1 PROTEIN, MOUSE; SHAB POTASSIUM CHANNEL;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; EPILEPTIC DISCHARGE; EVOKED RESPONSE; FEMALE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL NEURONAL CULTURE; IN VIVO STUDY; LONG TERM POTENTIATION; MALE; MORRIS WATER MAZE TEST; MOUSE; MUTANT; NERVE CELL EXCITABILITY; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; SEIZURE SUSCEPTIBILITY; SPATIAL LEARNING; SYNAPSE; WEIGHT REDUCTION; ACTION POTENTIAL; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; GENE DELETION; GENETICS; HIPPOCAMPUS; MAZE TEST; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY; PHENOTYPE; PHYSIOLOGY; SEIZURE;

ANIMALIA; MUS;

ACTION POTENTIALS; ANIMALS; CONVULSANTS; FLUROTHYL; GENE DELETION; HIPPOCAMPUS; LONG-TERM POTENTIATION; MAZE LEARNING; MICE; MICE, INBRED C57BL; NEURONS; PHENOTYPE; PILOCARPINE; SEIZURES; SHAB POTASSIUM CHANNELS;

EID: 84897962170     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/gbb.12120     Document Type: Article

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