Race-related health disparities and biological aging: Does rate of telomere shortening differ across blacks and whites?

Biological Psychology

Volumn 99, Issue 1, 2014, Pages 92-99

  Rewak, Marissa ^a   Buka, Stephen ^b   Prescott, Jennifer ^a,c   De Vivo, Immaculata ^a,c   Loucks, Eric B ^b   Kawachi, Ichiro ^a   Non, Amy L ^d   Kubzansky, Laura D ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BROWN UNIVERSITY   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d VANDERBILT UNIVERSITY   (United States)

Author keywords

Prospective follow up; Race, human; Social disparities in health; Social stress; Telomere; Telomere shortening

Indexed keywords

ADULTHOOD; AGE; AGING; ARTICLE; BODY MASS; CAUCASIAN; CHILD; COHORT ANALYSIS; DIET; EDUCATIONAL STATUS; ETHNICITY; FEMALE; HEALTH DISPARITY; HUMAN; HUMAN CELL; HYPOTHESIS; INFANT; LEUKOCYTE; LINEAR REGRESSION ANALYSIS; MALE; NEGRO; NORMAL HUMAN; PHYSICAL ACTIVITY; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SOCIAL STATUS; TELOMERE SHORTENING; UNITED STATES; ADULT; ANALYSIS OF VARIANCE; BLACK PERSON; GENETICS; HEALTH CARE DISPARITY; MIDDLE AGED; PHYSIOLOGY; REGRESSION ANALYSIS; SEX DIFFERENCE;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGING; ANALYSIS OF VARIANCE; COHORT STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HEALTHCARE DISPARITIES; HUMANS; INFANT; LEUKOCYTES; MALE; MIDDLE AGED; REGRESSION ANALYSIS; SEX FACTORS; TELOMERE SHORTENING;

EID: 84897946772     PISSN: 03010511     EISSN: 18736246     Source Type: Journal    
DOI: 10.1016/j.biopsycho.2014.03.007     Document Type: Article

References (45)

1. Adler N., Pantell M., O'Donovan A., Blackburn E., Cawthon R., Koster A., et al. Educational attainment and late life telomere length in the Health, Aging and Body Composition Study. Brain, Behavior, and Immunity 2012, 27:15-21.
2. Aviv A., Valdes A.M., Spector T.D. Human telomere biology: Pitfalls of moving from the laboratory to epidemiology. International Journal of Epidemiology 2006, 35(6):1424-1429.
3. Aviv A., Chen W., Gardner J.P., Kimura M., Brimacombe M., Cao X., et al. Leukocyte telomere dynamics: Longitudinal findings among young adults in the Bogalusa Heart Study. American Journal of Epidemiology 2009, 169(3):323-329.
4. Bain B.J. Ethnic and sex differences in the total and differential white cell count and platelet count. Journal of Clinical Pathology 1996, 49(8):664-666.
5. Barrett E.L.B., Richardson D.S. Sex differences in telomeres and lifespan. Aging Cell 2011, 10(6):913-921.
6. Cawthon R.M. Telomere measurement by quantitative PCR. Nucleic Acids Research 2002, 30(10):e47.
7. Cawthon R.M., Smith K.R., O'Brien E., Sivatchenko A., Kerber R.A. Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 2003, 361(9355):393-395.
8. Chen W., Gardner J.P., Kimura M., Brimacombe M., Cao X.J., Srinivasan S.R., et al. Leukocyte telomere length is associated with HDL cholesterol levels: The Bogalusa Heart Study. Atherosclerosis 2009, 205(2):620-625.
9. Chen W., Kimura M., Kim S., Cao X., Srinivasan S.R., Berenson G.S., et al. Longitudinal versus cross-sectional evaluations of leukocyte telomere length dynamics: Age-dependent telomere shortening is the rule. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2011, 66(3):312-319.
10. Cherkas L.F., Aviv A., Valdes A.M., Hunkin J.L., Gardner J.P., Surdulescu G.L., et al. The effects of social status on biological aging as measured by white-blood-cell telomere length. Aging Cell 2006, 5(5):361-365.
11. Clougherty J.E., Levy J.I., Kubzansky L.D., Ryan P.B., Suglia S.F., Canner M.J., et al. Synergistic effects of traffic-related air pollution and exposure to violence on urban asthma etiology. Environmental Health Perspectives 2007, 115(8):1140-1146.
12. De Vivo I., Prescott J., Wong J.Y.Y., Kraft P., Hankinson S.E., Hunter D.J. A prospective study of relative telomere length and postmenopausal breast cancer risk. Cancer Epidemiology Biomarkers & Prevention 2009, 18(4):1152-1156.
13. Diaz V.A., Mainous A.G., Player M.S., Everett C.J. Telomere length and adiposity in a racially diverse sample. International Journal of Obesity 2009, 34(2):261-265.
14. Dixon W.J., Yuen K.K. Trimming and winsorization: A review. Statistical Papers 1974, 15(2):157-170.
15. Ehrlenbach S., Willeit P., Kiechl S., Willeit J., Reindl M., Schanda K., et al. Influences on the reduction of relative telomere length over 10 years in the population-based Bruneck Study: Introduction of a well-controlled high-throughput assay. International Journal of Epidemiology 2009, 38(6):1725-1734.
16. Epel E.S., Blackburn E.H., Lin J., Dhabhar F.S., Adler N.E., Morrow J.D., et al. Accelerated telomere shortening in response to life stress. PNAS 2004, 101(49):17312-17315.
17. Epel E.S., Lin J., Wilhelm F.H., Wolkowitz O.M., Cawthon R., Adler N.E., et al. Cell aging in relation to stress arousal and cardiovascular disease risk factors. Psychoneuroendocrinology 2006, 31(3):277-287.
18. Fitzpatrick A.L., Kronmal R.A., Kimura M., Gardner J.P., Psaty B.M., Jenny N.S., et al. Leukocyte telomere length and mortality in the Cardiovascular Health Study. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2011, 66A(4):421-429.
19. Freedman D.S., Gates L., Flanders W.D., Van Assendelft O.W., Barboriak J.J., Joesoef M.R., et al. Black/white differences in leukocyte subpopulations in men. International Journal of Epidemiology 1997, 26(4):757-764.
20. Garcia-Rizo C., Fernandez-Egea E., Miller B.J., Oliveira C., Justicia A., Griffith J.K., et al. Abnormal glucose tolerance, white blood cell count, and telomere length in newly diagnosed, antidepressant-naïve patients with depression. Brain, Behavior, and Immunity 2012, 28:49-53.
21. Geronimus A.T., Bound J., Waidmann T.A., Colen C.G., Steffick D. Inequality in life expectancy, functional status, and active life expectancy across selected black and white populations in the United States. Demography 2001, 38(2):227-251.
22. Geronimus A.T., Hicken M., Keene D., Bound J. "Weathering" and age patterns of allostatic load scores among blacks and whites in the United States. American Journal of Public Health 2006, 96(5):826-833.
23. Geronimus A.T., Hicken M.T., Pearson J.A., Seashols S.J., Brown K.L., Cruz T.D. Do US black women experience stress-related accelerated biological aging?. Human Nature 2010, 21(1):19-38.
24. Grann V.R., Ziv E., Joseph C.K., Neugut A.I., Wei Y., Jacobson J.S., et al. Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean. British Journal of Haematology 2008, 143(2):288-293.
25. Harris S.E., Deary I.J., MacIntyre A., Lamb K., Radhakrishnan K., Starr J.M., et al. The association between telomere length, physical health, cognitive ageing, and mortality in non-demented older people. Neuroscience Letters 2006, 406(3):260-264.
26. Hoge E.A., Chen M.M., Metcalf C.A., Fischer L.E., Pollack M.H., DeVivo I. Loving-kindness meditation practice associated with longer telomeres in women. Brain, Behavior, and Immunity 2013, 32:159-163.
27. Hunt S.C., Chen W., Gardner J.P., Kimura M., Srinivasan S.R., Eckfeldt J.H., et al. Leukocyte telomeres are longer in African Americans than in whites: The National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study. Aging Cell 2008, 7(4):451-458.
28. Iwama H., Ohyashiki K., Ohyashiki J.H., Hayashi S., Yahata N., Ando K., et al. Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals. Human Genetics 1998, 102(4):397-402.
29. Lim E.M., Cembrowski G., Cembrowski M., Clarke G. Race-specific WBC and neutrophil count reference intervals. International Journal of Laboratory Hematology 2010, 32(6p2):590-597.
30. Murray C.J.L., Kulkarni S.C., Michaud C., Tomijima N., Bulzacchelli M.T., Iandiorio T.J., et al. Eight Americas: Investigating mortality disparities across races, counties, and race-counties in the United States. PLOS Medicine 2006, 3(9):1513-1524.
31. Manual for processing and collecting blood samples for viral serological study and instructions for completing virology forms 1964, 25-36. National Collaborative Perinatal Project.
32. Niswander K.R., Gordon M. The women and their pregnancies: The Collaborative Perinatal Study of the National Institute of Neurological Diseases and Stroke 1972, Saunders, Washington, D.C.: U.S. Government Printing Office.
33. Nordfjäll K., Svenson U., Norrback K.-F., Adolfsson R., Lenner P., Roos G. The individual blood cell telomere attrition rate is telomere length dependent. PLOS Genetics 2009, 5(2):e1000375.
34. O'Donovan A., Epel E., Lin J., Wolkowitz O., Cohen B., Maguen S., et al. Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder. Biological Psychiatry 2011, 70(5):465-471.
35. Okuda K., Bardeguez A., Gardner J.P., Rodriguez P., Ganesh V., Kimura M., et al. Telomere length in the newborn. Pediatric Research 2002, 52(3):377.
36. Roux A.V.D., Ranjit N., Jenny N.S., Shea S., Cushman M., Fitzpatrick A., et al. Race/ethnicity and telomere length in the Multi-Ethnic Study of Atherosclerosis. Aging Cell 2009, 8(3):251-257.
37. Serrano A.L., Andres V. Telomeres and cardiovascular disease: Does size matter?. Circulation Research 2004, 94:575-584.
38. Simon N.M., Smoller J.W., McNamara K.L., Maser R.S., Zalta A.K., Pollack M.H., et al. Telomere shortening and mood disorders: Preliminary support for a chronic stress model of accelerated aging. Biological Psychiatry 2006, 60(5):432-435.
39. Tyrka A.R., Price L.H., Kao H.T., Porton B., Marsella S.A., Carpenter L.L. Childhood maltreatment and telomere shortening: Preliminary support for an effect of early stress on cellular aging. Biological Psychiatry 2010, 67(6):531-534.
40. Valdes A.M., Andrew T., Gardner J.P., Kimura M., Oelsner E., Cherkas L.F., et al. Obesity, cigarette smoking, and telomere length in women. The Lancet 2005, 366(9486):662-664.
41. Wang H., Chen H., Gao X., McGrath M., Deer D., De Vivo I., et al. Telomere length and risk of Parkinson's disease. Movement Disorders 2008, 23(2):302-305.
42. Williams D.R., Mohammed S.A. Discrimination and racial disparities in health: Evidence and needed research. Journal of Behavioral Medicine 2009, 32(1):20-47.
43. Wong J.M.Y., Collins K. Telomere maintenance and disease. The Lancet 2003, 362(9388):983-988.
44. Wyatt S.B., Williams D.R., Calvin R., Henderson F.C., Walker E.R., Winters K. Racism and cardiovascular disease in African Americans. American Journal of the Medical Sciences 2003, 325(6):315-331.
45. Zhu H.D., Wang X.L., Gutin B., Davis C.L., Keeton D., Thomas J., et al. Leukocyte telomere length in healthy Caucasian and African-American adolescents: Relationships with race, sex, adiposity, adipokines, and physical activity. Journal of Pediatrics 2011, 158(2):215-220.