Abnormal glucose tolerance, white blood cell count, and telomere length in newly diagnosed, antidepressant-naïve patients with depression

Brain, Behavior, and Immunity

Volumn 28, Issue , 2013, Pages 49-53

  Garcia Rizo, Clemente ^a   Fernandez Egea, Emilio ^b,c   Miller, Brian J ^d   Oliveira, Cristina ^a   Justicia, Azucena ^b   Griffith, Jeffrey K ^e   Heaphy, Christopher M ^e   Bernardo, Miguel ^a,f,g   Kirkpatrick, Brian ^h  

^a HOSPITAL CLÍNIC   (Spain)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c CAMBRIDGESHIRE AND PETERBOROUGH NHS FOUNDATION TRUST   (United Kingdom)

^d MEDICAL COLLEGE OF GEORGIA   (United States)

^e UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^f INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^g CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

^h TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

Accelerated aging; Diabetes mellitus; Drug na ve; Glucose tolerance; Immunosenescence; Lymphopenia; Major depressive disorder; Telomere

Indexed keywords

ANTIDEPRESSANT AGENT; GLUCOSE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; IMPAIRED GLUCOSE TOLERANCE; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; LYMPHOCYTOPENIA; MAJOR DEPRESSION; MALE; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; TELOMERE; TELOMERE SHORTENING;

ADULT; BLOOD GLUCOSE; CASE-CONTROL STUDIES; DEPRESSIVE DISORDER, MAJOR; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INTERVIEW, PSYCHOLOGICAL; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; MALE; PSYCHIATRIC STATUS RATING SCALES; TELOMERE SHORTENING;

EID: 84872203489     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2012.11.009     Document Type: Article

References (44)

1. Adaikalakoteswari A., Balasubramanyam M., Ravikumar R., Deepa R., Mohan V. Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy. Atherosclerosis 2007, 195:83-89.
2. Anderson R.J., Freedland K.E., Clouse R.E., Lustman P.J. The prevalence of comorbid depression in adults with diabetes: a meta-analysis. Diabetes Care 2001, 24:1069-1078.
3. Balasubramanyam M., Adaikalakoteswari A., Monickaraj S.F., Mohan V. Telomere shortening & metabolic/vascular diseases. Indian J. Med. Res. 2007, 125:441-450.
4. Bender B.S., Nagel J.E., Adler W.H., Andres R. Absolute peripheral blood lymphocyte count and subsequent mortality of elderly men. The Baltimore Longitudinal Study of Aging. J. Am. Geriatr. Soc. 1986, 34:649-654.
5. Blume J., Douglas S.D., Evans D.L. Immune suppression and immune activation in depression. Brain Behav. Immun. 2011, 25:221-229.
6. Brown L.C., Majumdar S.R., Newman S.C., Johnson J.A. History of depression increases risk of type 2 diabetes in younger adults. Diabetes Care 2005, 28:1063-1067.
7. Brown A.D., Barton D.A., Lambert G.W. Cardiovascular abnormalities in patients with major depressive disorder: autonomic mechanisms and implications for treatment. CNS Drugs 2009, 23:583-602.
8. Cawthon R.M., Smith K.R., O'Brien E., Sivatchenko A., Kerber R.A. Association between telomere length in blood and mortality in people aged 60years or older. Lancet 2003, 361:393-395.
9. Collerton J., Martin-Ruiz C., Davies K., Hilkens C.M., Isaacs J., Kolenda C., Parker C., Dunn M., Catt M., Jagger C., von Zglinicki T., Kirkwood T.B. Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: Cross-sectional findings from the Newcastle 85+ Study. Mech. Ageing Dev. 2012, 133:456-466.
10. Darko D.F., Rose J., Gillin J.C., Golshan S., Baird S.M. Neutrophilia and lymphopenia in major mood disorders. Psychiatry Res. 1988, 25:243-251.
11. Derijks H.J., Meyboom R.H., Heerdink E.R., De Koning F.H., Janknegt R., Lindquist M., Egberts A.C. The association between antidepressant use and disturbances in glucose homeostasis: evidence from spontaneous reports. Eur. J. Clin. Pharmacol. 2008, 64:531-538.
12. Egede L.E. Effect of comorbid chronic diseases on prevalence and odds of depression in adults with diabetes. Psychosom. Med. 2005, 67:46-51.
13. Fernandez-Egea E., Bernardo M., Donner T., Conget I., Parellada E., Justicia A., Esmatjes E., Garcia-Rizo C., Kirkpatrick B. Metabolic profile of antipsychotic-naive individuals with non-affective psychosis. Br. J. Psychiatry 2009, 194:434-438.
14. Fernandez-Egea E., Bernardo M., Heaphy C.M., Griffith J.K., Parellada E., Esmatjes E., Conget I., Nguyen L., George V., Stoppler H., Kirkpatrick B. Telomere length and pulse pressure in newly diagnosed, antipsychotic-naive patients with nonaffective psychosis. Schizophr. Bull. 2009, 35:437-442.
15. Ferrando-Martinez S., Ruiz-Mateos E., Hernandez A., Gutierrez E., Rodriguez-Mendez Mdel M., Ordonez A., Leal M. Age-related deregulation of naive T cell homeostasis in elderly humans. Age (Dordr) 2011, 33:197-207.
16. Fitzpatrick A.L., Kronmal R.A., Gardner J.P., Psaty B.M., Jenny N.S., Tracy R.P., Walston J., Kimura M., Aviv A. Leukocyte telomere length and cardiovascular disease in the cardiovascular health study. Am. J. Epidemiol. 2007, 165:14-21.
17. Fordyce C.A., Heaphy C.M., Bisoffi M., Wyaco J.L., Joste N.E., Mangalik A., Baumgartner K.B., Baumgartner R.N., Hunt W.C., Griffith J.K. Telomere content correlates with stage and prognosis in breast cancer. Breast Cancer Res. Treat. 2006, 99:193-202.
18. Gabbay V., Klein R.G., Alonso C.M., Babb J.S., Nishawala M., De Jesus G., Hirsch G.S., Hottinger-Blanc P.M., Gonzalez C.J. Immune system dysregulation in adolescent major depressive disorder. J. Affect Disord. 2009, 115:177-182.
19. Grandinetti A., Kaholokula J.K., Chang H.K. Delineating the relationship between stress, depressive symptoms, and glucose intolerance. Diabetes Care 2000, 23:1443-1444.
20. Heuser I. Depression, endocrinologically a syndrome of premature aging?. Maturitas 2002, 41(Suppl. 1):S19-S23.
21. Hung Y.J., Hsieh C.H., Chen Y.J., Pei D., Kuo S.W., Shen D.C., Sheu W.H., Chen Y.C. Insulin sensitivity, proinflammatory markers and adiponectin in young males with different subtypes of depressive disorder. Clin. Endocrinol. (Oxf) 2007, 67:784-789.
22. Kassi E., Papavassiliou A.G. Could glucose be a proaging factor?. J. Cell Mol. Med. 2008, 12:1194-1198.
23. Kirkpatrick B., Fernandez-Egea E., Garcia-Rizo C., Bernardo M. Differences in glucose tolerance between deficit and nondeficit schizophrenia. Schizophr. Res. 2009, 107:122-127.
24. Knol M.J., Twisk J.W., Beekman A.T., Heine R.J., Snoek F.J., Pouwer F. Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetologia 2006, 49:837-845.
25. Knol M.J., Heerdink E.R., Egberts A.C., Geerlings M.I., Gorter K.J., Numans M.E., Grobbee D.E., Klungel O.H., Burger H. Depressive symptoms in subjects with diagnosed and undiagnosed type 2 diabetes. Psychosom. Med. 2007, 69:300-305.
26. Leo R., Di Lorenzo G., Tesauro M., Cola C., Fortuna E., Zanasi M., Troisi A., Siracusano A., Lauro R., Romeo F. Decreased plasma adiponectin concentration in major depression. Neurosci. Lett. 2006, 407:211-213.
27. Leo R., Di Lorenzo G., Tesauro M., Razzini C., Forleo G.B., Chiricolo G., Cola C., Zanasi M., Troisi A., Siracusano A., Lauro R., Romeo F. Association between enhanced soluble CD40 ligand and proinflammatory and prothrombotic states in major depressive disorder: pilot observations on the effects of selective serotonin reuptake inhibitor therapy. J. Clin. Psychiatry 2006, 67:1760-1766.
28. Lippi G., Montagnana M., Favaloro E.J., Franchini M. Mental depression and cardiovascular disease: a multifaceted, bidirectional association. Semin. Thromb. Hemost. 2009, 35:325-336.
29. Lung F.W., Chen N.C., Shu B.C. Genetic pathway of major depressive disorder in shortening telomeric length. Psychiatr. Genet. 2007, 17:195-199.
30. Marano G., Harnic D., Lotrionte M., Biondi-Zoccai G., Abbate A., Romagnoli E., Mazza M. Depression and the cardiovascular system: increasing evidence of a link and therapeutic implications. Expert Rev. Cardiovasc. Ther. 2009, 7:1123-1147.
31. Martin-Ruiz C., Dickinson H.O., Keys B., Rowan E., Kenny R.A., Von Zglinicki T. Telomere length predicts poststroke mortality, dementia, and cognitive decline. Ann. Neurol. 2006, 60:174-180.
32. Mueller P.S., Heninger G.R., McDonald R.K. Insulin tolerance test in depression. Arch. Gen. Psychiatry 1969, 21:587-594.
33. Nichols G.A., Brown J.B. Unadjusted and adjusted prevalence of diagnosed depression in type 2 diabetes. Diabetes Care 2003, 26:744-749.
34. Obana N., Takagi S., Kinouchi Y., Tokita Y., Sekikawa A., Takahashi S., Hiwatashi N., Oikawa S., Shimosegawa T. Telomere shortening of peripheral blood mononuclear cells in coronary disease patients with metabolic disorders. Intern. Med. 2003, 42:150-153.
35. Pan A., Ye X., Franco O.H., Li H., Yu Z., Zou S., Zhang Z., Jiao S., Lin X. Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study. J. Affect Disord. 2008, 109:75-82.
36. Rhee M.K., Musselman D., Ziemer D.C., Vaccarino V., Kolm P., Weintraub W.S., Caudle J.M., Varughese R.M., Irving J.M., Phillips L.S. Unrecognized glucose intolerance is not associated with depression. Screening for Impaired Glucose Tolerance study 3 (SIGT 3). Diabet. Med. 2008, 25:1361-1365.
37. Rosenberg S.D., Drake R.E., Wolford G.L., Mueser K.T., Oxman T.E., Vidaver R.M., Carrieri K.L., Luckoor R. Dartmouth Assessment of Lifestyle Instrument (DALI): a substance use disorder screen for people with severe mental illness. Am. J. Psychiatry 1998, 155:232-238.
38. Simon N.M., Smoller J.W., McNamara K.L., Maser R.S., Zalta A.K., Pollack M.H., Nierenberg A.A., Fava M., Wong K.K. Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging. Biol. Psychiatry 2006, 60:432-435.
39. Timonen M., Salmenkaita I., Jokelainen J., Laakso M., Harkonen P., Koskela P., Meyer-Rochow V.B., Peitso A., Keinanen-Kiukaanniemi S. Insulin resistance and depressive symptoms in young adult males: findings from Finnish military conscripts. Psychosom. Med. 2007, 69:723-728.
40. Wang, Y., Jia, Y., Chen, X., Ling, X., Liu, S., Xu, G., Huang, L., 2012. Hippocampal N-acetylaspartate and morning cortisol levels in drug-naive, first-episode patients with major depressive disorder: effects of treatment. J Psychopharmacol.
41. Wolkowitz O.M., Epel E.S., Reus V.I., Mellon S.H. Depression gets old fast: do stress and depression accelerate cell aging?. Depress Anxiety 2010, 27:327-338.
42. Wolkowitz O.M., Mellon S.H., Epel E.S., Lin J., Dhabhar F.S., Su Y., Reus V.I., Rosser R., Burke H.M., Kupferman E., Compagnone M., Nelson J.C., Blackburn E.H. Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress-preliminary findings. PLoS ONE 2011, 6:e17837.
43. Zheng P., Gao H.C., Li Q., Shao W.H., Zhang M.L., Cheng K., Yang de Y., Fan S.H., Chen L., Fang L., Xie P. Plasma metabonomics as a novel diagnostic approach for major depressive disorder. J. Proteome Res. 2012, 11:1741-1748.
44. Zorrilla E.P., Luborsky L., McKay J.R., Rosenthal R., Houldin A., Tax A., McCorkle R., Seligman D.A., Schmidt K. The relationship of depression and stressors to immunological assays: a meta-analytic review. Brain Behav. Immun. 2001, 15:199-226.