IGRP and insulin vaccination induce CD8+ T cell-mediated autoimmune diabetes in the RIP-CD80GP mouse

Clinical and Experimental Immunology

Volumn 176, Issue 2, 2014, Pages 199-206

  Fuchs, Y F ^a,b   Adler, K ^c   Lindner, A ^a   Karasinsky, A ^a   Wilhelm, C ^a   Weigelt, M ^a   Balke, H ^d   Fortsch K ^d   Mortler Hildebrandt, L F ^d   Harlan, D M ^e   Pechhold, K ^e   Ziegler, A G ^c,d   Bonifacio, E ^a,b  

^a CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^b GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^c Forschergruppe Diabetes eV   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Antigens peptides epitopes; Autoimmunity; Cytotoxic T cells; Diabetes

Indexed keywords

AMYLIN; CHROMOGRANIN A; DNA VACCINE; FREUND ADJUVANT; GLUCAGON; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN G; INSULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE VACCINE; PROINSULIN; PROTEIN; PROTEIN IGRP; SECRETOGRANIN V; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; ZINC TRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; AUTOIMMUNE DIABETES MELLITUS; AUTOIMMUNE DISEASE; CD8+ T LYMPHOCYTE; COMPARATIVE STUDY; CONTROLLED STUDY; DENDRITIC CELL; DIABETES MELLITUS; DIABETOGENESIS; DNA IMMUNIZATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; IMMUNOREACTIVITY; LYMPHOCYTIC INFILTRATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; SECRETORY GRANULE; SPLEEN CELL;

ANTIGENS/PEPTIDES/EPITOPES; AUTOIMMUNITY; CYTOTOXIC T CELLS; DIABETES;

ANIMALS; ANTIGENS, CD80; CD8-POSITIVE T-LYMPHOCYTES; DIABETES MELLITUS, TYPE 1; DNA; FREUND'S ADJUVANT; GLUCOSE-6-PHOSPHATASE; GLYCOPROTEINS; INSULIN; ISLETS OF LANGERHANS; KAPLAN-MEIER ESTIMATE; LIPIDS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC; PROTEIN PRECURSORS; RATS; TIME FACTORS; VACCINATION; VACCINES, DNA; VIRAL PROTEINS;

EID: 84897936951     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12263     Document Type: Article

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