-
1
-
-
70350366754
-
Glucose-6-phosphatase catalytic subunit gene family
-
Hutton JC, O'Brien RM. Glucose-6-phosphatase catalytic subunit gene family. J Biol Chem 2009;284:29241-29245
-
(2009)
J Biol Chem
, vol.284
, pp. 29241-29245
-
-
Hutton, J.C.1
O'Brien, R.M.2
-
2
-
-
33847620145
-
Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype
-
DOI 10.1007/s00125-006-0564-1
-
Wang Y, Martin CC, Oeser JK, et al. Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype. Diabetologia 2007;50:774-778 (Pubitemid 46355820)
-
(2007)
Diabetologia
, vol.50
, Issue.4
, pp. 774-778
-
-
Wang, Y.1
Martin, C.C.2
Oeser, J.K.3
Sarkar, S.4
McGuinness, O.P.5
Hutton, J.C.6
O'Brien, R.M.7
-
3
-
-
44449091627
-
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels
-
DOI 10.1126/science.1156849
-
Bouatia-Naji N, Rocheleau G, Van Lommel L, et al. A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science 2008;320:1085-1088 (Pubitemid 351929551)
-
(2008)
Science
, vol.320
, Issue.5879
, pp. 1085-1088
-
-
Bouatia-Naji, N.1
Rocheleau, G.2
Van Lommel, L.3
Lemaire, K.4
Schuit, F.5
Cavalcanti-Proenca, C.6
Marchand, M.7
Hartikainen, A.-L.8
Sovio, U.9
De Graeve, F.10
Rung, J.11
Vaxillaire, M.12
Tichet, J.13
Marre, M.14
Balkau, B.15
Weill, J.16
Elliott, P.17
Jarvelin, M.-R.18
Meyre, D.19
Polychronakos, C.20
Dina, C.21
Sladek, R.22
Froguel, P.23
more..
-
4
-
-
46749100599
-
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels
-
DOI 10.1172/JC134566
-
Chen WM, Erdos MR, Jackson AU, et al. Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest 2008;118:2620-2628 (Pubitemid 351949789)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.7
, pp. 2620-2628
-
-
Chen, W.-M.1
Erdos, M.R.2
Jackson, A.U.3
Saxena, R.4
Sanna, S.5
Silver, K.D.6
Timpson, N.J.7
Hansen, T.8
Orru, M.9
Piras, M.G.10
Bonnycastle, L.L.11
Wilier, C.J.12
Lyssenko, V.13
Shen, H.14
Kuusisto, J.15
Ebrahim, S.16
Sestu, N.17
Duren, W.L.18
Spada, M.C.19
Stringham, H.M.20
Scott, L.J.21
Olla, N.22
Swift, A.J.23
Najjar, S.24
Mitchell, B.D.25
Lawlor, D.A.26
Smith, G.D.27
Ben-Shlomo, Y.28
Andersen, G.29
Borch-Johnsen, K.30
Jorgensen, T.31
Saramies, J.32
Valle, T.T.33
Buchanan, T.A.34
Shuldiner, A.R.35
Lakatta, E.36
Bergman, R.N.37
Uda, M.38
Tuomilehto, J.39
Pedersen, O.40
Cao, A.41
Groop, L.42
Mohlke, K.L.43
Laakso, M.44
Schlessinger, D.45
Collins, F.S.46
Altshuler, D.47
Abecasis, G.R.48
Boehnke, M.49
Scuteri, A.50
Watanabe, R.M.51
more..
-
5
-
-
0037478632
-
+ T cells in autoimmune diabetes
-
DOI 10.1073/pnas.0932778100
-
Lieberman SM, Evans AM, Han B, et al. Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. Proc Natl Acad Sci USA 2003;100:8384-8388 (Pubitemid 36842554)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.14
, pp. 8384-8388
-
-
Lieberman, S.M.1
Evans, A.M.2
Han, B.3
Takaki, T.4
Vinnitskaya, Y.5
Caldwell, J.A.6
Serreze, D.V.7
Shabanowitz, J.8
Hunt, D.F.9
Nathenson, S.G.10
Santamaria, P.11
DiLorenzo, T.P.12
-
7
-
-
17844365884
-
+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: A novel beta cell autoantigen in type 1 diabetes
-
Mukherjee R, Wagar D, Stephens TA, Lee-Chan E, Singh B. Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: a novel beta cell autoantigen in type 1 diabetes. J Immunol 2005;174:5306-5315 (Pubitemid 40593169)
-
(2005)
Journal of Immunology
, vol.174
, Issue.9
, pp. 5306-5315
-
-
Mukherjee, R.1
Wagar, D.2
Stephens, T.A.3
Lee-Chan, E.4
Singh, B.5
-
8
-
-
33644548006
-
Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects
-
Yang J, Danke NA, Berger D, et al. Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects. J Immunol 2006;176:2781-2789
-
(2006)
J Immunol
, vol.176
, pp. 2781-2789
-
-
Yang, J.1
Danke, N.A.2
Berger, D.3
-
9
-
-
45249117656
-
Identification of novel IGRP epitopes targeted in type 1 diabetes patients
-
Jarchum I, Nichol L, Trucco M, Santamaria P, DiLorenzo TP. Identification of novel IGRP epitopes targeted in type 1 diabetes patients. Clin Immunol 2008;127:359-365
-
(2008)
Clin Immunol
, vol.127
, pp. 359-365
-
-
Jarchum, I.1
Nichol, L.2
Trucco, M.3
Santamaria, P.4
DiLorenzo, T.P.5
-
10
-
-
33644501795
-
HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes
-
Takaki T, Marron MP, Mathews CE, et al. HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes. J Immunol 2006;176:3257-3265
-
(2006)
J Immunol
, vol.176
, pp. 3257-3265
-
-
Takaki, T.1
Marron, M.P.2
Mathews, C.E.3
-
11
-
-
20944441042
-
Prevention of diabetes by manipulation of anti-IGRP autoimmunity: High efficiency of a low-affinity peptide
-
DOI 10.1038/nm1250
-
Han B, Serra P, Amrani A, et al. Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide. Nat Med 2005;11:645-652 (Pubitemid 40868305)
-
(2005)
Nature Medicine
, vol.11
, Issue.6
, pp. 645-652
-
-
Han, B.1
Serra, P.2
Amrani, A.3
Yamanouchi, J.4
Maree, A.F.M.5
Edelstein-Keshet, L.6
Santamaria, P.7
-
12
-
-
0029826977
-
B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: Analysis of a new 'speed congenic' stock of NOD.Igmu(null) mice
-
Serreze DV, Chapman HD, Varnum DS, et al. B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice. J Exp Med 1996;184:2049-2053 (Pubitemid 26404497)
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.5
, pp. 2049-2053
-
-
Serreze, D.V.1
Chapman, H.D.2
Varnum, D.S.3
Hanson, M.S.4
Reifsnyder, P.C.5
Richard, S.D.6
Fleming, S.A.7
Leiter, E.H.8
Shultz, L.D.9
-
13
-
-
4043132409
-
+ T cell clonotype AI4
-
Takaki T, Lieberman SM, Holl TM, et al. Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4. J Immunol 2004;173:2530-2541 (Pubitemid 39063112)
-
(2004)
Journal of Immunology
, vol.173
, Issue.4
, pp. 2530-2541
-
-
Takaki, T.1
Lieberman, S.M.2
Holl, T.M.3
Han, B.4
Santamaria, P.5
Serreze, D.V.6
DiLorenzo, T.P.7
-
14
-
-
9144271119
-
+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase
-
Lieberman SM, Takaki T, Han B, Santamaria P, Serreze DV, DiLorenzo TP. Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase. J Immunol 2004;173:6727-6734 (Pubitemid 39541058)
-
(2004)
Journal of Immunology
, vol.173
, Issue.11
, pp. 6727-6734
-
-
Lieberman, S.M.1
Takaki, T.2
Han, B.3
Santamaria, P.4
Serreze, D.V.5
DiLorenzo, T.P.6
-
15
-
-
77951776390
-
Genetics, pathogenesis and clinical interventions in type 1 diabetes
-
Bluestone JA, Herold K, Eisenbarth G. Genetics, pathogenesis and clinical interventions in type 1 diabetes. Nature 2010;464:1293-1300
-
(2010)
Nature
, vol.464
, pp. 1293-1300
-
-
Bluestone, J.A.1
Herold, K.2
Eisenbarth, G.3
-
16
-
-
17644361955
-
The NOD mouse: A model of immune dysregulation
-
DOI 10.1146/annurev.immunol.23.021704.115643
-
Anderson MS, Bluestone JA. The NOD mouse: a model of immune dysregulation. Annu Rev Immunol 2005;23:447-485 (Pubitemid 40563177)
-
(2005)
Annual Review of Immunology
, vol.23
, pp. 447-485
-
-
Anderson, M.S.1
Bluestone, J.A.2
-
17
-
-
0033001488
-
The NOD mouse model of type 1 diabetes: As good as it gets?
-
DOI 10.1038/9442
-
Atkinson MA, Leiter EH. The NOD mouse model of type 1 diabetes: as good as it gets? Nat Med 1999;5:601-604 (Pubitemid 29289413)
-
(1999)
Nature Medicine
, vol.5
, Issue.6
, pp. 601-604
-
-
Atkinson, M.A.1
Leiter, E.H.2
-
18
-
-
77952686356
-
In situ recognition of autoantigen as an essential gatekeeper in autoimmune CD8+ T cell inflammation
-
Wang J, Tsai S, Shameli A, Yamanouchi J, Alkemade G, Santamaria P. In situ recognition of autoantigen as an essential gatekeeper in autoimmune CD8+ T cell inflammation. Proc Natl Acad Sci USA 2010;107:9317-9322
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9317-9322
-
-
Wang, J.1
Tsai, S.2
Shameli, A.3
Yamanouchi, J.4
Alkemade, G.5
Santamaria, P.6
-
19
-
-
18744366947
-
Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice
-
DOI 10.1038/nature03523
-
Nakayama M, Abiru N, Moriyama H, et al. Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. Nature 2005;435:220-223 (Pubitemid 40685949)
-
(2005)
Nature
, vol.435
, Issue.7039
, pp. 220-223
-
-
Nakayama, M.1
Abiru, N.2
Moriyama, H.3
Babaya, N.4
Liu, E.5
Miao, D.6
Yu, L.7
Wegmann, D.R.8
Hutton, J.C.9
Elliott, J.F.10
Eisenbarth, G.S.11
-
20
-
-
33845316086
-
Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP
-
DOI 10.1172/JCI29602
-
Krishnamurthy B, Dudek NL, McKenzie MD, et al. Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP. J Clin Invest 2006;116:3258-3265 (Pubitemid 44878640)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.12
, pp. 3258-3265
-
-
Krishnamurthy, B.1
Dudek, N.L.2
McKenzie, M.D.3
Purcell, A.W.4
Brooks, A.G.5
Gellert, S.6
Colman, P.G.7
Harrison, L.C.8
Lew, A.M.9
Thomas, H.E.10
Kay, T.W.H.11
-
21
-
-
44449148889
-
Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice
-
Krishnamurthy B, Mariana L, Gellert SA, et al. Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice. J Immunol 2008;180:4458-4464
-
(2008)
J Immunol
, vol.180
, pp. 4458-4464
-
-
Krishnamurthy, B.1
Mariana, L.2
Gellert, S.A.3
-
22
-
-
0027361654
-
Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients
-
Itoh N, Hanafusa T, Miyazaki A, et al. Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients. J Clin Invest 1993;92:2313-2322 (Pubitemid 23333537)
-
(1993)
Journal of Clinical Investigation
, vol.92
, Issue.5
, pp. 2313-2322
-
-
Itoh, N.1
Hanafusa, T.2
Miyazaki, A.3
Miyagawa, J.-I.4
Yamagata, K.5
Yamamoto, K.6
Waguri, M.7
Imagawa, A.8
Tamura, S.9
Inada, M.10
Kawata, S.11
Tarui, S.12
Kono, N.13
Matsuzawa, Y.14
|