Development and partial validation of a mouse model for predicting drug hypersensitivity reactions

Journal of Immunotoxicology

Volumn 11, Issue 2, 2014, Pages 141-147

  Whritenour, Jessica ^a   Cole, Susan ^a   Zhu, Xu ^a   Li, Dingzhou ^a   Kawabata, Thomas T ^a  

^a PFIZER INC   (United States)

Author keywords

Drug allergy; Drug hypersensitivity; Idiosyncratic drug reactions; Immune mediated adverse drug reactions; Lymph node activation; Mouse model

Indexed keywords

ABACAVIR; AMOXICILLIN; CARBAMAZEPINE; CIMETIDINE; DICLOFENAC; FLECAINIDE; LAMOTRIGINE; METFORMIN; NEVIRAPINE; OFLOXACIN; PARACETAMOL; PENICILLIN DERIVATIVE; PHENOBARBITAL; PHENYTOIN; PROPRANOLOL; SULFAMETHOXAZOLE; VALPROIC ACID; VERAPAMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COUNT; CELL SUSPENSION; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DRUG HYPERSENSITIVITY; FEMALE; FLOW CYTOMETRY; LOCAL LYMPH NODE ASSAY; LYMPH NODE; LYMPH NODE PROLIFERATION ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SKIN TEST; ANIMAL; ANIMAL MODEL; C57BL MOUSE; IMMUNOLOGY; VALIDATION STUDY;

ANIMALS; DRUG HYPERSENSITIVITY; FEMALE; LYMPH NODES; MICE; MICE, INBRED C57BL; MODELS, ANIMAL;

EID: 84897880777     PISSN: 1547691X     EISSN: None     Source Type: Journal    
DOI: 10.3109/1547691X.2013.812164     Document Type: Article

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