Quercetin-3-O-glucronide inhibits noradrenaline binding to α2-adrenergic receptor, thus suppressing DNA damage induced by treatment with 4-hydroxyestradiol and noradrenaline in MCF-10A cells

Journal of Steroid Biochemistry and Molecular Biology

Volumn 143, Issue , 2014, Pages 122-129

  Yamazaki, Shunsuke ^a   Sakakibara, Hiroyuki ^b   Takemura, Hitomi ^c   Yasuda, Michiko ^a   Shimoi, Kayoko ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b UNIVERSITY OF MIYAZAKI   (Japan)

^c AICHI GAKUSEN UNIVERSITY   (Japan)

Author keywords

2 Adrenergic receptor; 4 Hydroxyestradiol; DNA damage; Human mammary epithelial MCF 10A cells; Noradrenaline; Quercetin 3 O glucronide

Indexed keywords

4 HYDROXYESTRADIOL; ALPHA 2 ADRENERGIC RECEPTOR; ANTINEOPLASTIC AGENT; ATM PROTEIN; BETA 2 ADRENERGIC RECEPTOR; CLONIDINE; HISTONE H2AX; ISOPRENALINE; MESSENGER RNA; NORADRENALIN; PROPRANOLOL; QUERCETIN 3 O GLUCRONIDE; QUERCETIN DERIVATIVE; RAUWOLSCINE; UNCLASSIFIED DRUG; 4-HYDROXYESTRADIOL; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; CATECHOL ESTROGEN; QUERCETIN; QUERCETIN 3-O-GLUCURONIDE;

ADRENAL GLAND; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER RISK; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG RECEPTOR BINDING; DRUG UPTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTONE PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; BREAST; CYTOLOGY; DRUG EFFECTS; FEMALE; GENETICS; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

ADRENERGIC ALPHA-AGONISTS; BLOTTING, WESTERN; BREAST; DNA DAMAGE; ESTROGENS, CATECHOL; FEMALE; HUMANS; NOREPINEPHRINE; QUERCETIN; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ADRENERGIC, ALPHA-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 84897865669     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2014.02.014     Document Type: Article

References (46)

1. F. Kamangar, G.M. Dores, and W.F. Anderson Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world J. Clin. Oncol. 24 14 2006 137 150
2. L. Bernstein, and R.K. Ross Endogenous hormones and breast cancer risk Epidemiol. Rev. 15 1 1993 48 65 (Pubitemid 23269070)
3. J.L. Kelsey, M.D. Gammon, and E.M. John Reproductive factors and breast cancer Epidemiol. Rev. 15 1 1993 36 47 (Pubitemid 23269069)
4. M.C. Pike, D.V. Spicer, L. Pahmoush, and M.F. Press Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk Epidemiol. Rev. 15 1 1993 17 35 (Pubitemid 23269068)
5. L.A.M. Castagnetta, O.M. Granata, A. Traina, B. Ravazzolo, M. Amoroso, M. Miele, V. Bellavia, B. Agostara, and G. Carruba Tissue content of hydroxyestrogens in relation to survival of breast cancer patients Clin. Cancer Res. 8 31 2002 3146 3155 (Pubitemid 35155024)
6. E. Cavalieri, and G.E. Rogan Catechol quinones of estragens in the initiation of breast, prostate, and other human cancers Ann. N.Y. Acad. Sci. 1089 2006 286 301 (Pubitemid 47092096)
7. M. Zahid, E. Kohli, M. Saeed, G.E. Rogan, and E. Cavalieri The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating, adducts: implications for tumor-initiating activity Chem. Res. Toxicol. 19 1 2006 164 172 (Pubitemid 43185475)
8. S. Yamazaki, H. Sakakibara, H. Takemura, and K. Shimoi 4-Hydroxyestradiol induces γ-H2AX in the presence of an inhibitor of catechol-O- methyltransferase in human breast cancer MCF-7 cells Genes Environ. 34 3 2012 129 135
9. W.M. Bonner, C.E. Redon, J.S. Dickey, A.J. Nakamura, O.A. Sedelinikova, S. Solier, and Y. Pommier γ-H2AX and cancer Nat. Rev. Cancer 8 12 2012 957 967
10. O.A. Sedelnikova, D.R. Pilch, C. Redon, and W.N. Bonner Histone H2AX in DNA repair Cancer Biol. Ther. 2 3 2003 233 235
11. D.M. Parkin International variation Oncogene 23 38 2004 6329 6340 (Pubitemid 39272833)
12. G.D. James, H.V. Berge-Landry, H.B. Valdimardottir, G.H. Montgomery, and D.H. Bovbjerg Urinary catecholamine levels in daily life are elevated in women at familial risk of breast cancer Psychoneuroendocrinology 29 7 2004 831 838 (Pubitemid 38716108)
13. K. Lillberg, P.K. Verkasalo, J. Kaprio, L. Teppo, H. Helenius, and M. Koskenvuo Stressful life events and risk of breast cancer in 10,808 women: a cohort study Am. J. Epidemiol. 157 5 2003 415 423 (Pubitemid 36258597)
14. E.K. Sloan, S.J. Priceman, B.F. Cox, S. Yu, M.A. Primentel, V. Tangkanangnkal, J.M. Arevalo, K. Morizono, B.D. Karanikolas, L. Wu, A.K. Sood, and S.W. Cole The sympathetic nervous system induces a metastatic switch in primary breast cancer Cancer Res. 70 18 2010 7042 7052
15. W.H. Vogel Coping, stress, stressors and health consequences Neuropsychobiology 13 3 1985 29 35
16. M.H. Antomi, S.K. Lutgendorf, S.W. Cole, F.S. Dhabhar, S.E. Sephton, P.G. McDnald, M. Stefanek, and A.K. Sood The influence of bio-behavioural factors on tumour biology: pathways and mechanisms Nat. Rev. Cancer 6 3 2006 240 248 (Pubitemid 43292567)
17. A. Bierhaus, J. Wolf, M. Andrassy, N. Rohleder, P.M. Humpert, D. Petrov, R. Fersti, M. Von Eynatten, T. Wendt, G. Rudofsky, M. Joswig, M. Morcos, M. Schwaninger, B.M. Ewen, C. Kirschbaum, and P.P. Nawroth A mechanism converting psychosocial stress into mononuclear cell activation PNAS 100 4 2003 1920 1925 (Pubitemid 36254549)
18. C.J. Daly, and J.C. Mc Grath Previously unsuspected widespread cellular and tissue distribution of β-adrenoceptors and its relevance to drug action Trends Pharmacol. Sci. 32 4 2011 219 226
19. J.G. Baker, S.J. Hill, and R.J. Summers Evolution of β-blockers: from anti-anginal drugs to ligand-directed signaling Trends Pharmacol. Sci. 32 4 2010 227 234
20. G. Shakhar, and S.B. Eliyahu In vivo β-adrenagic stimulation suppresses natural killer activity and compromises resistance to tumor metastasis in rats J. Immunol. 160 7 1998 3251 3258 (Pubitemid 28164714)
21. P.H. Thaker, L.Y. Han, A.A. Kamat, and J.M. Arevalo Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma Nat. Med. 12 8 2006 939 944 (Pubitemid 44175146)
22. D.G. Powe1, M.J. Voss, K.S. Zanker, H.O. Habashy, A.R. Green, I.O. Ellis, and F. Entschladen Beta-blocker drug therapy reduces secondary cancer formation Oncotarget 1 7 2010 628 638
23. L.H. Yao, Y.M. Jiang, J. Shi, F.A. Toma ́s-Barbera ́n, N. Datta, R. Singanusong, and S.S. Chen Flavonoids in food and their health benefits Plant Foods Hum. Nutr. 59 3 2004 113 122 (Pubitemid 40172010)
24. H. Takemura, H. Sakakibara, S. Yamazaki, and K. Shimoi Breast cancer and flavonoids - a role in prevention Curr. Pharm. Des. 19 34 2013 6125 6132
25. Y.J. Surh Cancer chemoprevention with dietary phytochemicals Nat. Rev. Cancer 3 10 2003 768 780
26. G. Williamson, D. Barron, K. Shimoi, and J. Terao In vitro biological properties of flavonoid conjugates found in vivo Free Radic. Res. 39 5 2005 457 469 (Pubitemid 40711878)
27. M.G. Hertog, P.C. Hollman, M.B. Katan, and D. Kromhout Intake of potentially anticarcinogenic avonoids and their determinants in adults in the Netherlands Nutr. Cancer 20 1 1993 21 29 (Pubitemid 23225364)
28. A. Scalbert, and G. Williamson Diretay intake and bioavailability of polyphenols J. Nutr. 130 8S Suppl. 2000 2073S 2085S
29. A.J. Day, M.S. DuPont, S. Ridley, M. Rhodes, M.J. Rhodes, and G. Williamson Deglycosylation of avonoid and isoavonoid glycosides by human small intestine and liver à-glucosidase activity FEBS Lett. 436 1 1998 71 75 (Pubitemid 28454609)
30. A.J. Day, F. Mellon, D. Barron, G. Sarrazin, M.R. Morgan, and G. Williamson Human metabolism of dietary avonoids: identification of plasma metabolites of quercetin Free Radic. Res. 35 6 2001 941 952 (Pubitemid 34065683)
31. W. Mullen, C.A. Edwards, and A. Crozier Absorption, excretion and metabolite profiling of methyl-, glucuronyl-, glucosyl- and sulpho-conjugates of quercetin in human plasma and urine after ingestion of onions Br. J. Nutr. 96 1 2006 107 116 (Pubitemid 44160903)
32. P.A. Kroon, M.N. Clifford, A. Crozier, A.J. Day, J.L. Donovan, C. Manach, and G. Williamson How should we assess the effects of exposure to dietary polyphenols in vitro? Am. J. Clin. Nutr. 80 1 2004 15 21 (Pubitemid 41115549)
33. K. Murota, A. Hotta, H. Ido, Y. Kawai, J.-H. Moon, K. Sekido, H. Hayashi, T. Inakuma, and J. Terao Antioxidant capacity of albumin-bound quercetin metabolites after onion consumption in humans J. Med. Invest. 54 2007 370 374 (Pubitemid 350143753)
34. L.P. Madhubhani, P. Hemachandra, R. Esala, P. Chandrasena, M. Shao-Nong Chen, D.C. Main, R.A. Lankin, B.M. Scism, G.F. Dietz, G.R.J. Pauli, and J.L. Thatcher Bolton Hops (Humulus lupulus) inhibits oxidative estrogen metabolism and estrogen-induced malignant transformation in human mammary epithelial cells (MCF-10A) Cancer Prev. Res. 5 2011 73 81
35. S.M. Vazquez, A.G. Mladovan, C. Perez, A. Bruzzone, and A. Baldi Human breast cell lines exhibit functional alpha(2)-adrenoceptors Cancer Chemother. Pharmacol. 58 1 2006 50 61
36. C. Shayo, N. Fernandez, B.L. Legnazzi, F. Monczor, and A. Mladovan Histamine H2 receptor desensitization: involvement of a select array of G protein-coupled receptor kinases Mol. Pharmacol. 60 5 2001 1049 1056 (Pubitemid 33027440)
37. C.C. Jansson, J.M. Savola, and K.E. Akerman Different sensitivity of alpha2A-C10and alpha 2C-C4 receptor subtypes in coupling to inhibition of cAMP accumulation Biochem. Biophys. Res. Commun. 199 2 1994 869 875
38. J.C. Ignacio, F.C. Lilian, and A.L. Isabel J. Steroid Biochem. Mol. Biol. 110 1-2 2008 170 175
39. S.M. Vazquez, O. Pignataro, and I.A. Luthy Alpha2-adrenergic effect on human breast cancer MCF-7 cells Breast Cancer Res. Treat. 55 1 1999 41 49 (Pubitemid 29353973)
40. Y. Cakir, H.K. Plummer II, P.K. Tithof, and H.M. Schuller à-Adrenergic andarachidonic acid-mediated growth regulation of human breast cancer cell lines Int. J. Oncol. 21 1 2002 153 157
41. Y. Nakayama, and N. Yamaguchi Role of cyclin B1 levels in DNA damage and DNA damage-induced senescence Int. Rev. Cell Mol. Biol. 305 2013 1937 6448
42. M. Algazi, G.P. Bureau, A. Flahault, M.G. Dondon, and M.G. Le Could treatments with à-blockers be associated with a reduction in cancer risk? Rev. Epidemiol. Sante. Publique. 52 1 2004 53 65 (Pubitemid 38468653)
43. M. Suzuki, and T. Takahashi Aberrant DNA replication in cancer Mutat. Res. 743-744 2013 111 117
44. S.V. Fernandez, I.H. Russo, and V. Russo Estradiol and its metabolites 4-hydroxyestradiol and 2-hydroxyestradiol induce mutations in human breast epithelial cells Int. J. Cancer 118 8 2006 1862 1868
45. H. Takemuraa, H. Uchiyama, T. Ohura, H. Sakakibara, R. Kuruto, T. Amagai, and K. Shimoi A methoxyflavonoid, chrysoeriol, selectively inhibits the formation of acarcinogenic estrogen metabolite in MCF-7 breast cancer cells J. Steroid Biochem. Mol. Biol. 118 2010 70 76
46. H. Takemura, T. Itoh, K. Yamamoto, H. Sakakibara, and K. Shimoi Selective inhibition of methoxyflavonoids on human CYP1B1 activity Bioorg. Med. Chem. 18 2010 6310 6315