메뉴 건너뛰기




Volumn 151, Issue 3, 2013, Pages 106-113

Indole and trans-chalcone attenuate amyloid β plaque accumulation in male wistar rat: In vivo effectiveness of two anti-amyloid scaffolds

Author keywords

Alzheimer; Beta amyloid; Indole; Trans chalcone; Wistar rat

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); CHALCONE; INDOLE; INDOLE DERIVATIVE; NEUROLEPTIC AGENT; PEPTIDE FRAGMENT;

EID: 84897803318     PISSN: 00039829     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (18)

References (46)
  • 1
    • 33747127059 scopus 로고    scopus 로고
    • A comparative study: Evaluation of antioxidant activity of melatonin and some indole derivatives
    • Ateş-Alagöz Z., Coban T., Sibel S.L. A comparative study: Evaluation of antioxidant activity of melatonin and some indole derivatives. Med. Chem. Res., 14: 169-179, 2005.
    • (2005) Med. Chem. Res. , vol.14 , pp. 169-179
    • Ateş-Alagöz, Z.1    Coban, T.2    Sibel, S.L.3
  • 3
    • 34249701122 scopus 로고    scopus 로고
    • The Effect of Intrahippocampal Beta Amyloid (1-42) Peptide Injection on Oxidant and Antioxidant Status in Rat Brain
    • Cetin, F. and Dincer S,. The Effect of Intrahippocampal Beta Amyloid (1-42) Peptide Injection on Oxidant and Antioxidant Status in Rat Brain. Ann. NY Acad. Sci., 1100: 510-517, 2007.
    • (2007) Ann. NY Acad. Sci. , vol.1100 , pp. 510-517
    • Cetin, F.1    Dincer, S.2
  • 4
    • 0033618295 scopus 로고    scopus 로고
    • Potent neuroprotective properties against the Alzheimer beta-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid
    • Chyan Y.J., Poeggeler B., Omar R.A., Chain D.G., Frangione B., Ghiso J., Pappolla M.A. Potent neuroprotective properties against the Alzheimer beta-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid. J. Biol. Chem., 274: 21937-21942, 1999.
    • (1999) J. Biol. Chem. , vol.274 , pp. 21937-21942
    • Chyan, Y.J.1    Poeggeler, B.2    Omar, R.A.3    Chain, D.G.4    Frangione, B.5    Ghiso, J.6    Pappolla, M.A.7
  • 5
    • 79551538975 scopus 로고    scopus 로고
    • Revisiting dietary antioxidants, neurodegeneration and dementia
    • Craggs L. and Kalaria R.N,. Revisiting dietary antioxidants, neurodegeneration and dementia. Neuroreport, 22: 1-3, 2011.
    • (2011) Neuroreport , vol.22 , pp. 1-3
    • Craggs, L.1    Kalaria, R.N.2
  • 6
    • 67650783216 scopus 로고    scopus 로고
    • Mechanism-based treatments for Alzheimer's disease
    • Davies P. and Koppel J,. Mechanism-based treatments for Alzheimer's disease. Dialogues Clin. Neurosci., 11: 159-169, 2009.
    • (2009) Dialogues Clin. Neurosci. , vol.11 , pp. 159-169
    • Davies, P.1    Koppel, J.2
  • 8
    • 77954553168 scopus 로고    scopus 로고
    • Alzheimer's disease is incurable but preventable
    • de la Torre J.C. Alzheimer's disease is incurable but preventable. J. Alzheimers Dis., 20: 861-870, 2010.
    • (2010) J. Alzheimers Dis. , vol.20 , pp. 861-870
    • de la Torre, J.C.1
  • 9
    • 40849116488 scopus 로고    scopus 로고
    • Structure and function of enzymes involved in the biosynthesis of phenylpropanoids
    • Ferrer J.L., Austin M.B., Stewart C. Jr., Noel J.P. Structure and function of enzymes involved in the biosynthesis of phenylpropanoids. Plant. Physiol. Biochem., 46: 356-370, 2008.
    • (2008) Plant. Physiol. Biochem. , vol.46 , pp. 356-370
    • Ferrer, J.L.1    Austin, M.B.2    Stewart Jr., C.3    Noel, J.P.4
  • 10
    • 0026070054 scopus 로고
    • Effects of injected Alzheimer beta-amyloid cores in rat brain
    • Frautschy S.A., Baird A., Cole G.M. Effects of injected Alzheimer beta-amyloid cores in rat brain. Proc. Natl. Acad. Sci. USA, 88:8362-6, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8362-8366
    • Frautschy, S.A.1    Baird, A.2    Cole, G.M.3
  • 11
    • 18244389436 scopus 로고    scopus 로고
    • The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease
    • Gandy S. The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease. J. Clin. Invest., 115: 1121-1129, 2005.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1121-1129
    • Gandy, S.1
  • 12
    • 0021996712 scopus 로고
    • Prolonged ethanol consumption influences shuttle box and passive avoidance performance in rats
    • Guaza C. and Borrell J,. Prolonged ethanol consumption influences shuttle box and passive avoidance performance in rats. Physiol. Behav., 34: 163-165, 1985.
    • (1985) Physiol. Behav. , vol.34 , pp. 163-165
    • Guaza, C.1    Borrell, J.2
  • 13
    • 84856240878 scopus 로고    scopus 로고
    • Effect of phenolic compounds against Abeta aggregation and Abeta-induced toxicity in transgenic C
    • Jagota S. and Rajadas J,. Effect of phenolic compounds against Abeta aggregation and Abeta-induced toxicity in transgenic C. elegans. Neurochem. Res., 37: 40-48, 2012.
    • (2012) elegans. Neurochem. Res. , vol.37 , pp. 40-48
    • Jagota, S.1    Rajadas, J.2
  • 14
    • 0026631036 scopus 로고
    • The seminal role of beta-amyloid in the pathogenesis of Alzheimer disease
    • Joachim C.L. and Selkoe D.J,. The seminal role of beta-amyloid in the pathogenesis of Alzheimer disease. Alzheimer Dis. Assoc. Disord., 6: 7-34, 1992.
    • (1992) Alzheimer Dis. Assoc. Disord. , vol.6 , pp. 7-34
    • Joachim, C.L.1    Selkoe, D.J.2
  • 15
    • 80055038350 scopus 로고    scopus 로고
    • Trans-Chalcone prevents VEGF expression and retinal neovascularization in the ischemic retina
    • Lamoke F., Labazi M., Montemari A., Parisi G., Varano M., Bartoli M. Trans-Chalcone prevents VEGF expression and retinal neovascularization in the ischemic retina. Exp. Eye Res., 93: 350-354, 2011.
    • (2011) Exp. Eye Res. , vol.93 , pp. 350-354
    • Lamoke, F.1    Labazi, M.2    Montemari, A.3    Parisi, G.4    Varano, M.5    Bartoli, M.6
  • 16
    • 33645095476 scopus 로고    scopus 로고
    • Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond
    • Lipton S.A. Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. Nat. Rev. Drug Discov., 5: 160-170, 2006.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 160-170
    • Lipton, S.A.1
  • 17
    • 0028172886 scopus 로고
    • Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red
    • Lorenzo A. and Yankner B.A,. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc. Natl. Acad. Sci. USA, 91: 12243-12247, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12243-12247
    • Lorenzo, A.1    Yankner, B.A.2
  • 19
    • 80052921123 scopus 로고    scopus 로고
    • Alzheimers disease: emerging trends in small molecule therapies
    • Mohamed T. and Rao P.P.N,. Alzheimers disease: emerging trends in small molecule therapies. Curr. Med. Chem., 18: 4299-4320, 2011.
    • (2011) Curr. Med. Chem. , vol.18 , pp. 4299-4320
    • Mohamed, T.1    Rao, P.P.N.2
  • 21
    • 36749011905 scopus 로고    scopus 로고
    • Inhibition of amyloid fibrillation of lysozyme by indole derivatives: possible mechanism of action
    • Morshedi D., Rezaei-Ghaleh N., Ebrahim-Habibi A., Ahmadian S., Nemat-Gorgani M. Inhibition of amyloid fibrillation of lysozyme by indole derivatives: possible mechanism of action. FEBS J., 274: 6415-6425, 2007.
    • (2007) FEBS J. , vol.274 , pp. 6415-6425
    • Morshedi, D.1    Rezaei-Ghaleh, N.2    Ebrahim-Habibi, A.3    Ahmadian, S.4    Nemat-Gorgani, M.5
  • 22
    • 79551613722 scopus 로고    scopus 로고
    • Core structure of flavonoids precursor as an antihyperglycemic and antihyperlipidemic agent: an in vivo study in rats
    • Najafian M., Ebrahim-Habibi A., Yaghmaei P., Parivar K., Larijani B. Core structure of flavonoids precursor as an antihyperglycemic and antihyperlipidemic agent: an in vivo study in rats. Acta Biochim. Pol., 57: 553, 2010.
    • (2010) Acta Biochim. Pol. , vol.57 , pp. 553
    • Najafian, M.1    Ebrahim-Habibi, A.2    Yaghmaei, P.3    Parivar, K.4    Larijani, B.5
  • 31
    • 0035875690 scopus 로고    scopus 로고
    • Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis
    • Praticò D., Uryu K., Leight S., Trojanoswki J.Q., Lee V.M. Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J. Neurosci., 21: 4183- 4187, 2001.
    • (2001) J. Neurosci. , vol.21
    • Praticò, D.1    Uryu, K.2    Leight, S.3    Trojanoswki, J.Q.4    Lee, V.M.5
  • 32
    • 4544236922 scopus 로고    scopus 로고
    • Acetylcholinesterase inhibitors as a starting point towards improved Alzheimer's disease therapeutics
    • Recanatini M. and Valenti P,. Acetylcholinesterase inhibitors as a starting point towards improved Alzheimer's disease therapeutics. Curr. Pharm. Des., 10: 3157-3166, 2004.
    • (2004) Curr. Pharm. Des. , vol.10 , pp. 3157-3166
    • Recanatini, M.1    Valenti, P.2
  • 33
    • 84859755505 scopus 로고    scopus 로고
    • Alzheimer's disease and the amyloid cascade hypothesis: a critical review
    • Reitz C. Alzheimer's disease and the amyloid cascade hypothesis: a critical review. Int. J. Alzheimers. Dis., 369808, 2012.
    • (2012) Int. J. Alzheimers. Dis. , pp. 369808
    • Reitz, C.1
  • 34
    • 84861078831 scopus 로고    scopus 로고
    • A review: inflammatory process in Alzheimer's disease, role of cytokines
    • Rubio-Perez J.M. and Morillas-Ruiz J.M,. A review: inflammatory process in Alzheimer's disease, role of cytokines. ScientificWorldJournal 756357, 2012.
    • (2012) ScientificWorldJournal , pp. 756357
    • Rubio-Perez, J.M.1    Morillas-Ruiz, J.M.2
  • 35
    • 84875007601 scopus 로고    scopus 로고
    • An overview on potential neuroprotective compounds for management of Alzheimer's disease
    • Sheikh I.A., Ali R., Dar T.A., Kamal M.A. An overview on potential neuroprotective compounds for management of Alzheimer's disease. CNS Neurol. Disord. Drug Targets, 11: 1006-1011, 2012.
    • (2012) CNS Neurol. Disord. Drug Targets , vol.11 , pp. 1006-1011
    • Sheikh, I.A.1    Ali, R.2    Dar, T.A.3    Kamal, M.A.4
  • 36
    • 84858187825 scopus 로고    scopus 로고
    • Cytoprotective activity of a transchalcone against hydrogen peroxide induced toxicity in hepatocellular carcinoma (HepG2) cells
    • Sikander M., Malik S., Yadav D., Biswas S., Katare D.P., Jain S.K. Cytoprotective activity of a transchalcone against hydrogen peroxide induced toxicity in hepatocellular carcinoma (HepG2) cells. Asian Pac. J. Cancer Prev., 12: 2513-2516, 2011.
    • (2011) Asian Pac. J. Cancer Prev. , vol.12 , pp. 2513-2516
    • Sikander, M.1    Malik, S.2    Yadav, D.3    Biswas, S.4    Katare, D.P.5    Jain, S.K.6
  • 38
    • 84884877254 scopus 로고    scopus 로고
    • Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain
    • Sultana R., Perluigi M., Allan Butterfield D. Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain. Free Radic. Biol. Med., 62: 157-169, 2012.
    • (2012) Free Radic. Biol. Med. , vol.62 , pp. 157-169
    • Sultana, R.1    Perluigi, M.2    Allan Butterfield, D.3
  • 39
    • 33645988190 scopus 로고    scopus 로고
    • Organofluorine inhibitors of amyloid fibrillogenesis
    • Török M., Abid M., Mhadgut S.C., Török B. Organofluorine inhibitors of amyloid fibrillogenesis. Biochemistry, 45: 5377-5383, 2006.
    • (2006) Biochemistry , vol.45 , pp. 5377-5383
    • Török, M.1    Abid, M.2    Mhadgut, S.C.3    Török, B.4
  • 40
    • 82255161797 scopus 로고    scopus 로고
    • Flavonoids as acetylcholinesterase inhibitors
    • Uriarte-Pueyo I. and Calvo M.I,. Flavonoids as acetylcholinesterase inhibitors. Curr. Med. Chem., 18: 5289-5302, 2011.
    • (2011) Curr. Med. Chem. , vol.18 , pp. 5289-5302
    • Uriarte-Pueyo, I.1    Calvo, M.I.2
  • 41
    • 0037038816 scopus 로고    scopus 로고
    • Beta-Secretase (BACE) as a drug target for alzheimer's disease
    • Vassar R. Beta-Secretase (BACE) as a drug target for alzheimer's disease. Adv. Drug Deliv. Rev., 54: 1589-1602, 2002.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. 1589-1602
    • Vassar, R.1
  • 42
    • 84866893801 scopus 로고    scopus 로고
    • Corruption and spread of pathogenic proteins in neurodegenerative diseases
    • Walker L.C. and LeVine H,. Corruption and spread of pathogenic proteins in neurodegenerative diseases. J. Biol. Chem., 287: 33109-33115, 2012.
    • (2012) J. Biol. Chem. , vol.287 , pp. 33109-33115
    • Walker, L.C.1    LeVine, H.2
  • 43
    • 42149135452 scopus 로고    scopus 로고
    • Effect of melatonin and melatonylvalpromide on beta-amyloid and neurofilaments in N2a cells
    • Wang X.C., Zhang Y.C., Chatterjie N., Grundke- Iqbal I., Iqbal K., Wang J.Z. Effect of melatonin and melatonylvalpromide on beta-amyloid and neurofilaments in N2a cells. Neurochem. Res., 33: 1138-1144, 2008.
    • (2008) Neurochem. Res. , vol.33 , pp. 1138-1144
    • Wang, X.C.1    Zhang, Y.C.2    Chatterjie, N.3    Grundke-Iqbal, I.4    Iqbal, K.5    Wang, J.Z.6
  • 44
    • 84655167890 scopus 로고    scopus 로고
    • Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease
    • Williams R.J. and Spencer J.P,. Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease. Free Radic. Biol. Med., 52: 35-45, 2012.
    • (2012) Free Radic. Biol. Med. , vol.52 , pp. 35-45
    • Williams, R.J.1    Spencer, J.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.