Mechanisms of dopamine D1 receptor-mediated ERK1/2 activation in the parkinsonian striatum and their modulation by metabotropic glutamate receptor type 5

Journal of Neuroscience

Volumn 34, Issue 13, 2014, Pages 4728-4740

  Fieblinger, Tim ^a   Sebastianutto, Irene ^a   Alcacer, Cristina ^a   Bimpisidis, Zisis ^a   Maslava, Natallia ^a   Sandberg, Sabina ^a   Engblom, David ^b   Angela Cenci, M ^a  

^a LUND UNIVERSITY   (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

Author keywords

D1 receptor; Dopamine; ERK1 2; MGluR5; Parkinson's disease; Striatum

Indexed keywords

1 [[6 (3 METHOXYESTRA 1, 3, 5 (10) TRIEN 17BETA YL) AMINO] HEXYL] 1H PYRROLE 2, 5 DIONE; 1, 4 DIAMINO 1, 4 BIS (2 AMINOPHENYLTHIO) 2, 3 DICYANOBUTADIENE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL) MALEIMIDE; 2, 3, 4, 5 TETRAHYDRO 7, 8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 3 [(2 METHYL 4 THIAZOLYL) ETHYNYL] PYRIDINE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 4 BENZYL ALPHA (4 HYDROXYPHENYL) BETA METHYL 1 PIPERIDINEPROPANOL; 6 CYANO 7 NITRO 2, 3 QUINOXALINEDIONE; 8 CHLORO 2, 3, 4, 5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ACTIN; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIZOCILPINE; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR STIMULATING AGENT; ETHYLENE GLYCOL 1, 2 BIS (2 AMINOPHENYL) ETHER N, N, N', N' TETRAACETIC ACID; GLUTAMATE RECEPTOR 1; IONOTROPIC RECEPTOR; ISRADIPINE; KT 5720; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXIDOPAMINE; PICROTOXIN; RYANODINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CORPUS STRIATUM; DENERVATION; DOWNSTREAM PROCESSING; ENZYME PHOSPHORYLATION; FEMALE; FLUORESCENCE MICROSCOPY; GENE SILENCING; IMMUNOHISTOCHEMISTRY; METABOLIC ACTIVATION; MOUSE; NEUROMODULATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RODENT; SYNAPTIC TRANSMISSION; WESTERN BLOTTING;

D1 RECEPTOR; DOPAMINE; ERK1/2; MGLUR5; PARKINSON'S DISEASE; STRIATUM;

ADRENERGIC AGENTS; ANIMALS; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; DOPAMINE AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OXIDOPAMINE; PARKINSON DISEASE; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, METABOTROPIC GLUTAMATE 5; RECEPTORS, DOPAMINE D1; THIAZOLES; TYROSINE 3-MONOOXYGENASE;

EID: 84897585156     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2702-13.2014     Document Type: Article

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