Placental oxidative stress and decreased global DNA methylation are corrected by copper in the Cohen diabetic rat

Toxicology and Applied Pharmacology

Volumn 276, Issue 3, 2014, Pages 220-230

  Ergaz, Zivanit ^a   Guillemin, Claire ^b   Neeman azulay, Meytal ^a   Weinstein Fudim, Liza ^a   Stodgell, Christopher J ^c   Miller, Richard K ^c   Szyf, Moshe ^b   Ornoy, Asher ^a  

^a HEBREW UNIVERSITY   (Israel)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF ROCHESTER   (United States)

Author keywords

Copper; Diabetes; DNA methylation; Oxidative stress; Placenta; Tempol

Indexed keywords

CASPASE 3; COPPER; COPPER SULFATE; DRINKING WATER; SUCROSE; TEMPOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIET; DIET SUPPLEMENTATION; DNA METHYLATION; EMBRYO; FEMALE; FETUS WEIGHT; HIGH SUCROSE LOW COPPER DIET; HYPOXIA; IMMUNOHISTOCHEMISTRY; MATING; NONHUMAN; OXIDATIVE STRESS; PLACENTA WEIGHT; PREGNANCY; PROTEIN CONTENT; RAT;

ANIMALIA; RATTUS;

COPPER; DIABETES; DNA METHYLATION; OXIDATIVE STRESS; PLACENTA; TEMPOL;

ANIMALS; APOPTOSIS; COPPER; CYCLIC N-OXIDES; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; DNA METHYLATION; FEMALE; FETAL DEVELOPMENT; IMMUNOHISTOCHEMISTRY; LITTER SIZE; OXIDATIVE STRESS; PLACENTA; PREGNANCY; RATS; RATS, WISTAR; SPIN LABELS;

EID: 84897549663     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.02.017     Document Type: Article

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