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Volumn 54, Issue 11, 2004, Pages 843-849

Hypoxia-inducible factor-2α is involved in enhanced apoptosis in the placenta from pregnancies with fetal growth restriction

Author keywords

Apoptosis; Fetal growth restriction; Fetoplacental vascular endothelium; Hypoxia inducible factors; Placenta; Syncytiotrophoblast

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; UNCLASSIFIED DRUG;

EID: 11244299726     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2004.01750.x     Document Type: Article
Times cited : (18)

References (36)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-57.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 3
    • 0031447022 scopus 로고    scopus 로고
    • Increased placental apoptosis in intrauterine growth restriction
    • Smith SC, Baker PN, Symonds EM. Increased placental apoptosis in intrauterine growth restriction. Am J Obstet Gynecol 1997; 177: 1395-401.
    • (1997) Am J Obstet Gynecol , vol.177 , pp. 1395-1401
    • Smith, S.C.1    Baker, P.N.2    Symonds, E.M.3
  • 5
    • 0036583261 scopus 로고    scopus 로고
    • Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression
    • Levy R, Smith SD, Yusuf K et al. Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression. Am J Obstet Gynecol 2002; 186: 1056-61.
    • (2002) Am J Obstet Gynecol , vol.186 , pp. 1056-1061
    • Levy, R.1    Smith, S.D.2    Yusuf, K.3
  • 6
    • 0036153117 scopus 로고    scopus 로고
    • Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation
    • Ishihara N, Matsuo H, Murakoshi H, Laoag-Fernandez JB, Samoto T, Maruo T. Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation. Am J Obstet Gynecol 2002; 186: 158-66.
    • (2002) Am J Obstet Gynecol , vol.186 , pp. 158-166
    • Ishihara, N.1    Matsuo, H.2    Murakoshi, H.3    Laoag-Fernandez, J.B.4    Samoto, T.5    Maruo, T.6
  • 7
    • 0028572541 scopus 로고
    • Cytotoxicity of tumour necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts
    • Yui J, Garcia-Lloret M, Wegmann TG, Guilbert LJ. Cytotoxicity of tumour necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts. Placenta 1994; 15: 819-35.
    • (1994) Placenta , vol.15 , pp. 819-835
    • Yui, J.1    Garcia-Lloret, M.2    Wegmann, T.G.3    Guilbert, L.J.4
  • 8
    • 0033233243 scopus 로고    scopus 로고
    • Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
    • Semenza GL. Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Bio 1999; 15: 551-78.
    • (1999) Annu Rev Cell Dev Bio , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 9
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A 1995; 92: 5510-14.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 10
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza GL, Wang GL. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 1992; 12: 5447-54.
    • (1992) Mol Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 11
    • 0037073695 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1 alpha by transcriptional and translational mechanisms
    • Page EL, Robitaille GA, Pouyssegur J, Richard DE. Induction of hypoxia-inducible factor-1 alpha by transcriptional and translational mechanisms. J Biol Chem 2002; 277: 48 403-9.
    • (2002) J Biol Chem , vol.277
    • Page, E.L.1    Robitaille, G.A.2    Pouyssegur, J.3    Richard, D.E.4
  • 12
    • 0032189844 scopus 로고    scopus 로고
    • Induction of endothelial PAS domain protein-1 by hypoxia: Characterization and comparison with hypoxia-inducible factor-1 alpha
    • Wiesener MS, Turley H, Allen WE et al. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1 alpha. Blood 1998; 92: 2260-68.
    • (1998) Blood , vol.92 , pp. 2260-2268
    • Wiesener, M.S.1    Turley, H.2    Allen, W.E.3
  • 13
    • 0031020884 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
    • Tian H, McKnight SL, Russell DW. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev 1997; 11: 72-82.
    • (1997) Genes Dev , vol.11 , pp. 72-82
    • Tian, H.1    McKnight, S.L.2    Russell, D.W.3
  • 14
    • 0032213236 scopus 로고    scopus 로고
    • The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
    • Tian H, Hammer RE, Matsumoto AM, Russell DW, McKnight SL. The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes Dev 1998; 12: 3320-24.
    • (1998) Genes Dev , vol.12 , pp. 3320-3324
    • Tian, H.1    Hammer, R.E.2    Matsumoto, A.M.3    Russell, D.W.4    McKnight, S.L.5
  • 15
    • 0034682513 scopus 로고    scopus 로고
    • The transcription factor EPAS-1/hypoxia-inducible factor 2 alpha plays an important role in vascular remodeling
    • Peng J, Zhang L, Drysdale L, Fong GH. The transcription factor EPAS-1/hypoxia-inducible factor 2 alpha plays an important role in vascular remodeling. Proc Natl Acad Sci USA 2001; 97: 8386-91.
    • (2001) Proc Natl Acad Sci USA , vol.97 , pp. 8386-8391
    • Peng, J.1    Zhang, L.2    Drysdale, L.3    Fong, G.H.4
  • 16
    • 0032581277 scopus 로고    scopus 로고
    • Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
    • Carmeliet P, Dor Y, Herbert JM et al. Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 1998; 394: 485-90.
    • (1998) Nature , vol.394 , pp. 485-490
    • Carmeliet, P.1    Dor, Y.2    Herbert, J.M.3
  • 17
    • 0035914436 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-2 (HIF-2) is involved in the apoptotic response to hypoglycemia but not to hypoxia
    • Brusselmans K, Bono F, Maxwell P et al. Hypoxia-inducible factor-2 (HIF-2) is involved in the apoptotic response to hypoglycemia but not to hypoxia. J Biol Chem 2001; 276: 39 192-6.
    • (2001) J Biol Chem , vol.276
    • Brusselmans, K.1    Bono, F.2    Maxwell, P.3
  • 18
    • 0033566792 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 alpha mediates hypoxia-induced delayed neuronal death that involves p53
    • Halterman MW, Miller CC, Federoff HJ. Hypoxia-inducible factor-1 alpha mediates hypoxia-induced delayed neuronal death that involves p53. J Neurosci 1999; 19: 6818-24.
    • (1999) J Neurosci , vol.19 , pp. 6818-6824
    • Halterman, M.W.1    Miller, C.C.2    Federoff, H.J.3
  • 19
    • 0033873636 scopus 로고    scopus 로고
    • Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta
    • Rajakumar A, Conrad KP. Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta. Biol Reprod 2000; 63: 559-69.
    • (2000) Biol Reprod , vol.63 , pp. 559-569
    • Rajakumar, A.1    Conrad, K.P.2
  • 20
    • 0035143802 scopus 로고    scopus 로고
    • Selective overexpression of the hypoxia-inducible transcription factor, HIF-2 alpha, in placentas from women with preeclampsia
    • Rajakumar A, Whitelock KA, Weissfeld LA, Daftary AR, Markovic N, Conrad KP. Selective overexpression of the hypoxia-inducible transcription factor, HIF-2 alpha, in placentas from women with preeclampsia. Biol Reprod 2001; 64: 499-506.
    • (2001) Biol Reprod , vol.64 , pp. 499-506
    • Rajakumar, A.1    Whitelock, K.A.2    Weissfeld, L.A.3    Daftary, A.R.4    Markovic, N.5    Conrad, K.P.6
  • 21
    • 0020355658 scopus 로고
    • Intrauterine growth of live born Japanese infants between 28 and 42 weeks of gestation
    • Sato A, Akama M, Yamanobe H. Intrauterine growth of live born Japanese infants between 28 and 42 weeks of gestation. Acta Obstet Gynaecol Jpn 1982; 34: 1535-8.
    • (1982) Acta Obstet Gynaecol Jpn , vol.34 , pp. 1535-1538
    • Sato, A.1    Akama, M.2    Yamanobe, H.3
  • 22
    • 0032883567 scopus 로고    scopus 로고
    • Comparison of alterations in fetal regional arterial vascular resistance in appropriate-for-gestational-age singleton, twin and triplet pregnancies
    • Akiyama M, Kuno A, Tanaka Y et al. Comparison of alterations in fetal regional arterial vascular resistance in appropriate-for-gestational-age singleton, twin and triplet pregnancies. Hum Reprod 1999; 14: 2635-43.
    • (1999) Hum Reprod , vol.14 , pp. 2635-2643
    • Akiyama, M.1    Kuno, A.2    Tanaka, Y.3
  • 23
    • 18744431478 scopus 로고    scopus 로고
    • Expression of BCL-2, BAX and BAK in the trophoblast layer of the term human placenta: A unique model of apoptosis within a syncytium
    • Ratts VS, Tao XJ, Webster CB et al. Expression of BCL-2, BAX and BAK in the trophoblast layer of the term human placenta: a unique model of apoptosis within a syncytium. Placenta 2000; 21: 361-6.
    • (2000) Placenta , vol.21 , pp. 361-366
    • Ratts, V.S.1    Tao, X.J.2    Webster, C.B.3
  • 24
    • 0031888155 scopus 로고    scopus 로고
    • Apoptosis in human chorionic villi and decidua during normal embryonic development and spontaneous abortion in the first trimester
    • Kokawa K, Shikone T, Nakano R. Apoptosis in human chorionic villi and decidua during normal embryonic development and spontaneous abortion in the first trimester. Placenta 1998; 19: 21-6.
    • (1998) Placenta , vol.19 , pp. 21-26
    • Kokawa, K.1    Shikone, T.2    Nakano, R.3
  • 25
    • 0031887146 scopus 로고    scopus 로고
    • Apoptosis in human chorionic villi and decidua in normal and ectopic pregnancy
    • Kokawa K, Shikone T, Nakano R. Apoptosis in human chorionic villi and decidua in normal and ectopic pregnancy. Mol Hum Reprod 1998; 4: 87-91.
    • (1998) Mol Hum Reprod , vol.4 , pp. 87-91
    • Kokawa, K.1    Shikone, T.2    Nakano, R.3
  • 26
    • 0032983892 scopus 로고    scopus 로고
    • Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall
    • DiFederico E, Genbacev O, Fisher SJ. Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall. Am J Pathol 1999; 155: 293-301.
    • (1999) Am J Pathol , vol.155 , pp. 293-301
    • DiFederico, E.1    Genbacev, O.2    Fisher, S.J.3
  • 27
    • 0033954382 scopus 로고    scopus 로고
    • To be, or not to be, that is the question. Apoptosis in human trophoblast
    • Levy R, Nelson DM. To be, or not to be, that is the question. Apoptosis in human trophoblast. Placenta 2000; 21: 1-13.
    • (2000) Placenta , vol.21 , pp. 1-13
    • Levy, R.1    Nelson, D.M.2
  • 28
    • 0038710247 scopus 로고    scopus 로고
    • Impaired oxygen-dependent reduction of HIF-1 alpha and -2 alpha proteins in pre-eclamptic placentae
    • Rajakumar A, Doty K, Daftary A, Harger G, Conrad KP. Impaired oxygen-dependent reduction of HIF-1 alpha and -2 alpha proteins in pre-eclamptic placentae. Placenta 2002; 24: 199-208.
    • (2002) Placenta , vol.24 , pp. 199-208
    • Rajakumar, A.1    Doty, K.2    Daftary, A.3    Harger, G.4    Conrad, K.P.5
  • 29
    • 0344436031 scopus 로고    scopus 로고
    • Identification of vascular endothelial growth factor (VEGF) receptor-2 (Flk-1) promoter/enhancer sequences sufficient for angioblast and endothelial cell-specific transcription in transgenic mice
    • Kappel A, Ronicke V, Damert A, Flamme I, Risau W, Breier G. Identification of vascular endothelial growth factor (VEGF) receptor-2 (Flk-1) promoter/enhancer sequences sufficient for angioblast and endothelial cell-specific transcription in transgenic mice. Blood 1999; 93: 4284-92.
    • (1999) Blood , vol.93 , pp. 4284-4292
    • Kappel, A.1    Ronicke, V.2    Damert, A.3    Flamme, I.4    Risau, W.5    Breier, G.6
  • 30
    • 0033593219 scopus 로고    scopus 로고
    • Oxygen-regulated and transactivating domains in endothelial PAS protein 1: Comparison with hypoxia-inducible factor-1 alpha
    • O'Rourke JF, Tian YM, Ratcliffe PJ, Pugh CW. Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1 alpha. J Biol Chem 1999; 274: 2060-71.
    • (1999) J Biol Chem , vol.274 , pp. 2060-2071
    • O'Rourke, J.F.1    Tian, Y.M.2    Ratcliffe, P.J.3    Pugh, C.W.4
  • 31
    • 0038788826 scopus 로고    scopus 로고
    • Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1 alpha (HIF-1 alpha): Role of cytoplasmic trapping of HIF-2 alpha
    • Park SK, Dadak AM, Haase VH, Fontana L, Giaccia AJ, Johnson RS. Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1 alpha (HIF-1 alpha): role of cytoplasmic trapping of HIF-2 alpha. Mol Cell Biol 2003; 23: 4959-71.
    • (2003) Mol Cell Biol , vol.23 , pp. 4959-4971
    • Park, S.K.1    Dadak, A.M.2    Haase, V.H.3    Fontana, L.4    Giaccia, A.J.5    Johnson, R.S.6
  • 32
    • 0031000736 scopus 로고    scopus 로고
    • A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1 alpha regulates the VEGF expression and is potentially involved in lung and vascular development
    • Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii-Kuriyama Y. A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1 alpha regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci U S A 1997; 94: 4273-8.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 4273-4278
    • Ema, M.1    Taya, S.2    Yokotani, N.3    Sogawa, K.4    Matsuda, Y.5    Fujii-Kuriyama, Y.6
  • 33
    • 0041440036 scopus 로고    scopus 로고
    • The HIF family member EPAS1/HIF-2 alpha is required for normal hematopoiesis in mice
    • Scortegagna M, Morris MA, Oktay Y, Bennett M, Garcia JA. The HIF family member EPAS1/HIF-2 alpha is required for normal hematopoiesis in mice. Blood 2003; 102: 1634-40.
    • (2003) Blood , vol.102 , pp. 1634-1640
    • Scortegagna, M.1    Morris, M.A.2    Oktay, Y.3    Bennett, M.4    Garcia, J.A.5
  • 34
    • 85047691081 scopus 로고    scopus 로고
    • Heterozygous deficiency of hypoxia-inducible factor-2 alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia
    • Brusselmans K, Compernolle V, Tjwa M et al. Heterozygous deficiency of hypoxia-inducible factor-2 alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia. J Clin Invest 2003; 111: 1519-27.
    • (2003) J Clin Invest , vol.111 , pp. 1519-1527
    • Brusselmans, K.1    Compernolle, V.2    Tjwa, M.3
  • 35
    • 0030846190 scopus 로고    scopus 로고
    • Oxygen and placental villous development: Origins of fetal hypoxia
    • Kingdom JC, Kaufmann P. Oxygen and placental villous development: origins of fetal hypoxia. Placenta 1997; 18: 613-21.
    • (1997) Placenta , vol.18 , pp. 613-621
    • Kingdom, J.C.1    Kaufmann, P.2
  • 36
    • 0041896849 scopus 로고    scopus 로고
    • Placental-fetal interrelationship in IUGR fetuses - A review
    • Pardi G, Marconi AM, Cetin I. Placental-fetal interrelationship in IUGR fetuses - a review. Placenta 2002; 23: S136-41.
    • (2002) Placenta , vol.23
    • Pardi, G.1    Marconi, A.M.2    Cetin, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.