Kinetic evidence for a two-stage mechanism of protein denaturation by guanidinium chloride

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 13, 2014, Pages 4856-4861

  Jha, Santosh Kumar ^a   Marqusee, Susan ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

Dry molten globule; Protein unfolding; Steady state FRET

Indexed keywords

GUANIDINE; RIBONUCLEASE H; TRYPTOPHAN;

ARTICLE; CONFORMATIONAL TRANSITION; DISSOLUTION; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HYDROGEN BOND; HYDROPHOBICITY; KINETICS; NONHUMAN; POPULATION; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN SECONDARY STRUCTURE; PROTEIN UNFOLDING; SOLVATION;

DRY MOLTEN GLOBULE; PROTEIN UNFOLDING; STEADY-STATE FRET;

CIRCULAR DICHROISM; ESCHERICHIA COLI; FLUORESCENCE; GUANIDINE; KINETICS; NITROBENZOATES; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN UNFOLDING; RIBONUCLEASE H; SOLVENTS; SULFHYDRYL COMPOUNDS; TRYPTOPHAN;

EID: 84897547979     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1315453111     Document Type: Article

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