Scaffolds to control inflammation and facilitate dental pulp regeneration

Journal of Endodontics

Volumn 40, Issue 4 SUPPL., 2014, Pages

  Colombo, John S ^a,b   Moore, Amanda N ^b   Hartgerink, Jeffrey D ^b   D'Souza, Rena N ^a  

^a UNIVERSITY OF UTAH   (United States)

^b RICE UNIVERSITY   (United States)

Author keywords

Biomaterials; dental pulp; endodontics; inflammation; pulp regeneration; resolvins; tissue engineering

Indexed keywords

BIOMATERIAL; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID;

DENTAL PULP NECROSIS; HUMAN; IMMUNOLOGY; MACROPHAGE; PHYSIOLOGY; PULPITIS; REGENERATION; TISSUE SCAFFOLD; TOOTH PULP; TOOTH, NONVITAL;

BIOCOMPATIBLE MATERIALS; DENTAL PULP; DENTAL PULP NECROSIS; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; HUMANS; MACROPHAGES; PULPITIS; REGENERATION; TISSUE SCAFFOLDS; TOOTH, NONVITAL;

EID: 84897497803     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2014.01.019     Document Type: Article

References (108)

1. R. Harris, and C.J. Griffin The fine structure of the mature odontoblasts and cell rich zone of the human dental pulp Aust Dent J 14 1969 168 177
2. B.K. Berkovitz, G.R. Holland, and B. Moxham Oral Anatomy, Embryology and Histology 2002 Mosby Edinburgh
3. A. Nanci Ten Cate's Oral Histology: Development, Structure, and Function 2007 Elsevier Health Sciences Philadelphia
4. A. Linde The extracellular matrix of the dental pulp and dentin J Dent Res 64 1985 Spec No:523-9
5. Y. Iwasaki, H. Otsuka, and N. Yanagisawa et al. In situ proliferation and differentiation of macrophages in dental pulp Cell Tissue Res 346 2011 99 109
6. A.J. Sloan, and A.J. Smith Stem cells and the dental pulp: potential roles in dentine regeneration and repair Oral Dis 13 2007 151 157
7. A.J. Sloan, and R.J. Waddington Dental pulp stem cells: what, where, how? Int J Paediatr Dent 19 2009 61 70
8. G. Schmalz, and K.M. Galler Tissue injury and pulp regeneration J Dent Res 90 2011 828 829
9. L. Casagrande, M. Cordeiro, and S. Nör et al. Dental pulp stem cells in regenerative dentistry Odontology 99 2011 1 7
10. A. Balic, H.L. Aguila, and M.J. Caimano et al. Characterization of stem and progenitor cells in the dental pulp of erupted and unerupted murine molars Bone 46 2010 1639 1651
11. M. Miura, S. Gronthos, and M. Zhao et al. SHED: stem cells from human exfoliated deciduous teeth Proc Natl Acad Sci U S A 100 2003 5807 5812
12. M.J. Sigal, J.E. Aubin, and A.R. Ten Cate et al. The odontoblast process extends to the dentinoenamel junction: an immunocytochemical study of rat dentine J Histochem Cytochem 32 1984 872 877
13. S. Gronthos, M. Mankani, and J. Brahim et al. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo Proc Natl Acad Sci U S A 97 2000 13625 13630
14. D. Tziafas, A.J. Smith, and H. Lesot Designing new treatment strategies in vital pulp therapy J Dent 28 2000 77 92
15. Y. Harichane, A. Hirata, and S. Dimitrova-Nakov et al. Pulpal progenitors and dentin repair Adv Dent Res 23 2011 307 312
16. L.M. Lin, and P.A. Rosenberg Repair and regeneration in endodontics Int Endod J 44 2011 889 906
17. R. Waddington, S. Waddington, and C. Youde et al. Isolation of distinct progenitor stem cell populations from dental pulp Cells Tissues Organs 189 2009 268 274
18. R. d'Aquino, A. Graziano, and M. Sampaolesi et al. Human postnatal dental pulp cells co-differentiate into osteoblasts and endotheliocytes: a pivotal synergy leading to adult bone tissue formation Cell Death Differ 14 2007 1162 1171
19. K. Iohara, L. Zheng, and H. Wake et al. A novel stem cell source for vasculogenesis in ischemia: subfraction of side population cells from dental pulp Stem Cells 26 2008 2408 2418
20. N. Six, K. Tompkins, and D. Septier et al. Recruitment and characterization of the cells involved in reparative dentin formation in the exposed rat molar pulp after implantation of amelogenin gene splice products A+ 4 and A-4 Oral Biosci Med 1 2004 35 44
21. K. Iohara, M. Murakami, and N. Takeuchi et al. A novel combinatorial therapy with pulp stem cells and granulocyte colony-stimulating factor for total pulp regeneration Stem Cells Transl Med 2 2013 521 533
22. A. Volponi, M. Kawasaki, and P.T. Sharpe Adult human gingival epithelial cells as a source for whole-tooth bioengineering J Dent Res 92 2013 329 334
23. I. Slutzky-Goldberg, H. Slutzky, and C. Gorfil et al. Restoration of endodontically treated teeth review and treatment recommendations Int J Dent 2009 2009 150251
24. S. Kermanshahi, J. Santerre, and D. Cvitkovitch et al. Biodegradation of resin-dentin interfaces increases bacterial microleakage J Dent Res 89 2010 996 1001
25. E.G. Başaran, E. Ayna, and M. Halifeoǧlu Microleakage of endodontically treated teeth restored with 3 different adhesive systems and 4 different fiber-reinforced posts J Prosthet Dent 107 2012 239 251
26. N. Takahashi, and B. Nyvad The role of bacteria in the caries process: ecological perspectives J Dent Res 90 2011 294 303
27. R.A. Burne, L. Zeng, and S.J. Ahn et al. Progress dissecting the oral microbiome in caries and health Adv Dent Res 24 2012 77 80
28. L. Torlakovic, V. Klepac-Ceraj, and B. Ogaard et al. Microbial community succession on developing lesions on human enamel J Oral Microbiol 4 2012
29. G. Bergenholtz Inflammatory response of the dental pulp to bacterial irritation J Endod 7 1981 100 104
30. T. Izumi, I. Kobayashi, and K. Okamura et al. Immunohistochemical study on the immunocompetent cells of the pulp in human non-carious and carious teeth Arch Oral Biol 40 1995 609 614
31. P.R. Cooper, Y. Takahashi, and L.W. Graham et al. Inflammation- regeneration interplay in the dentine-pulp complex J Dent 38 2010 687 697
32. P.R. Cooper, and A.J. Smith Molecular mediators of pulp inflammation and regeneration Endod Top 28 2013 90 105
33. M. Zehnder, F.J. Wegehaupt, and T. Attin A first study on the usefulness of matrix metalloproteinase 9 from dentinal fluid to indicate pulp inflammation J Endod 37 2011 17 20
34. M. Goldberg, J.C. Farges, and S. Lacerda-Pinheiro et al. Inflammatory and immunological aspects of dental pulp repair Pharmacol Res 58 2008 137 147
35. F.W. Paula-Silva, A. Ghosh, and L.A. Silva et al. TNF-α promotes an odontoblastic phenotype in dental pulp cells J Dent Res 88 2009 339 344
36. M. Yamaguchi, T. Kojima, and M. Kanekawa et al. Neuropeptides stimulate production of interleukin-1β, interleukin-6, and tumor necrosis factor-α in human dental pulp cells Inflamm Res 53 2004 199 204
37. J.L. McLachlan, A.J. Sloan, and A.J. Smith et al. S100 and cytokine expression in caries Infect Immun 72 2004 4102 4108
38. A. Bletsa, E. Berggreen, and I. Fristad et al. Cytokine signalling in rat pulp interstitial fluid and transcapillary fluid exchange during lipopolysaccharide-induced acute inflammation J Physiol 573 2006 225 236
39. J.L. Roberts, J.Y. Maillard, and R.J. Waddington et al. Development of an ex vivo coculture system to model pulpal infection by Streptococcus anginosus group bacteria J Endod 39 2013 49 56
40. J.C. Farges, J.F. Keller, and F. Carrouel et al. Odontoblasts in the dental pulp immune response J Exp Zool B Mol Dev Evol 312B 2009 425 436
41. O. Veerayutthwilai, M.R. Byers, and T.T. Pham et al. Differential regulation of immune responses by odontoblasts Oral Microbiol Immunol 22 2007 5 13
42. L.G. Levin, A. Rudd, and A. Bletsa et al. Expression of IL-8 by cells of the odontoblast layer in vitro Eur J Oral Sci 107 1999 131 137
43. B.N. Brown, B.D. Ratner, and S.B. Goodman et al. Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine Biomaterials 33 2012 3792 3802
44. D.L. Laskin Macrophages and inflammatory mediators in chemical toxicity: a battle of forces Chem Res Toxicol 22 2009 1376 1385
45. M. Benoit, B. Desnues, and J.L. Mege Macrophage polarization in bacterial infections J Immunol 181 2008 3733 3739
46. R.D. Stout, and J. Suttles Functional plasticity of macrophages: reversible adaptation to changing microenvironments J Leukoc Biol 76 2004 509 513
47. Q. Cao, Y. Wang, and D. Zheng et al. IL-10/TGF-β-modified macrophages induce regulatory T cells and protect against adriamycin nephrosis J Am Soc Nephrol 21 2010 933 942
48. C.N. Serhan, and N.A. Petasis Resolvins and protectins in inflammation resolution Chem Rev 111 2011 5922 5943
49. A. Ariel, and C.N. Serhan Resolvins and protectins in the termination program of acute inflammation Trends Immunol 28 2007 176 183
50. M.J. Zhang, and M. Spite Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids Annu Rev Nutr 32 2012 203 227
51. S. Hong, and Y. Lu Omega-3 fatty acid-derived resolvins and protectins in inflammation resolution and leukocyte functions: targeting novel lipid mediator pathways in mitigation of acute kidney injury Front Immunol 4 2013 13
52. N.B. Janakiram, A. Mohammed, and C.V. Rao Role of lipoxins, resolvins, and other bioactive lipids in colon and pancreatic cancer Cancer Metastasis Rev 30 2011 507 523
53. G. Fredman, and C.N. Serhan Specialized pro-resolving lipid derived fatty acid mediators: wiring the circuitry of effector immune homeostasis Oral Wound Healing 2012 John Wiley & Sons 57 80
54. K.K. Katuri, C. Swarna, and N.D. Swamy Role of lipoxins, resolvins and protectins in mediating inflammation - review Int J Dent Clin 4 2012 37 39
55. C.N. Serhan, R. Yang, and K. Martinod et al. Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions J Exp Med 206 2009 15 23
56. C.N. Serhan, and N. Chiang Resolution phase lipid mediators of inflammation: agonists of resolution Curr Opin Pharmacol 13 2013 632 640
57. C.N. Serhan, C.B. Clish, and J. Brannon et al. Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing J Exp Med 192 2000 1197 1204
58. M. Arita, M. Yoshida, and S. Hong et al. Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis Proc Natl Acad Sci U S A 102 2005 7671 7676
59. G.L. Bannenberg, N. Chiang, and A. Ariel et al. Molecular circuits of resolution: formation and actions of resolvins and protectins J Immunol 174 2005 4345 4355
60. H.N. Lee, and Y.J. Surh Therapeutic potential of resolvins in the prevention and treatment of inflammatory disorders Biochem Pharmacol 84 2012 1340 1350
61. J.W. Winkler, J. Uddin, and C.N. Serhan et al. Stereocontrolled total synthesis of the potent anti-inflammatory and pro-resolving lipid mediator resolvin D3 and its aspirin-triggered 17R-epimer Org Lett 15 2013 1424 1427
62. S. Krishnamoorthy, A. Recchiuti, and N. Chiang et al. Resolvin D1 binds human phagocytes with evidence for proresolving receptors Proc Nat Acad Sci 107 2010 1660 1665
63. M. Arita, F. Bianchini, and J. Aliberti et al. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1 J Exp Med 201 2005 713 722
64. S. Schif-Zuck, N. Gross, and S. Assi et al. Saturated-efferocytosis generates pro-resolving CD11blow macrophages: modulation by resolvins and glucocorticoids Eur J Immunol 41 2011 366 379
65. M. Spite, L.V. Norling, and L. Summers et al. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis Nature 461 2009 1287 1291
66. M. Samson, A.L. Edinger, and P. Stordeur et al. ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strains Eur J Immunol 28 1998 1689 1700
67. H. Hasturk, A. Kantarci, and E. Goguet-Surmenian et al. Resolvin E1 regulates inflammation at the cellular and tissue level and restores tissue homeostasis in vivo J Immunol 179 2007 7021 7029
68. L. Gao, D. Faibish, and G. Fredman et al. Resolvin E1 and chemokine-like receptor 1 mediate bone preservation J Immunol 190 2013 689 694
69. N. Yu, A. Plachokova, and F. Yang et al. Engineering of dental tissues: scaffolds and preclinical models G.T.J. Huang, I. Thesleff, Stem Cells in Craniofacial Development and Regeneration 2013 Wiley-Blackwell Hoboken, NJ 409 429
70. M. Gebhardt, P.E. Murray, and K.N. Namerow et al. Cell survival within pulp and periodontal constructs J Endod 35 2009 63 66
71. D.J. Mooney, C. Powell, and J. Piana et al. Engineering dental pulp-like tissue in vitro Biotechnol Prog 12 1996 865 868
72. S. Chandrahasa, P.E. Murray, and K.N. Namerow Proliferation of mature ex vivo human dental pulp using tissue engineering scaffolds J Endod 37 2011 1236 1239
73. R.M. El-Backly, A.G. Massoud, and A.M. El-Badry et al. Regeneration of dentine/pulp-like tissue using a dental pulp stem cell/poly(lactic-co-glycolic) acid scaffold construct in New Zealand white rabbits Aust Endod J 34 2008 52 67
74. E.K. Moioli, P.A. Clark, and X. Xin et al. Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering Adv Drug Deliv Rev 59 2007 308 324
75. G.T. Huang, T. Yamaza, and L.D. Shea et al. Stem/progenitor cell-mediated de novo regeneration of dental pulp with newly deposited continuous layer of dentin in an in vivo model Tissue Eng Part A 16 2009 605 615
76. P. Hänseler, U.W. Jung, and R.E. Jung et al. Analysis of hydrolyzable polyethylene glycol hydrogels and deproteinized bone mineral as delivery systems for glycosylated and non-glycosylated bone morphogenetic protein-2 Acta Biomater 8 2012 116 123
77. D.S. Thoma, K. Subramani, and F.E. Weber et al. Biodegradation, soft and hard tissue integration of various polyethylene glycol hydrogels: a histomorphometric study in rabbits Clin Oral Implants Res 22 2011 1247 1254
78. P.M. Visakh, A. Mathew, and S. Thomas Natural polymers: their blends, composites and nanocomposites: state of art, new challenges and opportunities S. Thomas, P.M. Visakh, A.P. Mathew, Advances in Natural Polymers 2013 Springer Berlin, Germany 1 20
79. A. Rizk, and A.B. Rabie Human dental pulp stem cells expressing transforming growth factor β3 transgene for cartilage-like tissue engineering Cytotherapy 15 2013 712 725
80. I. Cantón, R. Mckean, and M. Charnley et al. Development of an ibuprofen-releasing biodegradable PLA/PGA electrospun scaffold for tissue regeneration Biotechnol Bioeng 105 2010 396 408
81. A. Murua, E. Herran, and G. Orive et al. Design of a composite drug delivery system to prolong functionality of cell-based scaffolds Int J Pharm 407 2011 142 150
82. S.E. Bae, J.S. Son, and K. Park et al. Fabrication of covered porous PLGA microspheres using hydrogen peroxide for controlled drug delivery and regenerative medicine J Control Release 133 2009 37 43
83. A. Lamprecht, N. Ubrich, and H. Yamamoto et al. Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease J Pharmacol Exp Ther 299 2001 775 781
84. F. Danhier, E. Ansorena, and J.M. Silva et al. PLGA-based nanoparticles: an overview of biomedical applications J Control Release 161 2012 505 522
85. J.Y. Kim, X. Xin, and E.K. Moioli et al. Regeneration of dental-pulp-like tissue by chemotaxis-induced cell homing Tissue Eng Part A 16 2010 3023 3031
86. G.T. Huang, W. Sonoyama, and J. Chen et al. In vitro characterization of human dental pulp cells: various isolation methods and culturing environments Cell Tissue Res 324 2006 225 236
87. K. Nakao, M. Itoh, and Y. Tomita et al. FGF-2 potently induces both proliferation and DSP expression in collagen type I gel cultures of adult incisor immature pulp cells Biochem Biophys Res Commun 325 2004 1052 1059
88. K.Y. Lee, and D.J. Mooney Hydrogels for tissue engineering Chem Rev 101 2001 1869 1880
89. Z. Yuan, H. Nie, and S. Wang et al. Biomaterial selection for tooth regeneration Tissue Eng Part B Rev 17 2011 373 388
90. K.-H. Park, H. Kim, and S. Moon et al. Bone morphogenic protein-2 (BMP-2) loaded nanoparticles mixed with human mesenchymal stem cell in fibrin hydrogel for bone tissue engineering J Biosci Bioeng 108 2009 530 537
91. K.M. Galler, A.C. Cavender, and U. Koeklue et al. Bioengineering of dental stem cells in a PEGylated fibrin gel Regen Med 6 2011 191 200
92. K.Y. Lee, and D.J. Mooney Alginate: properties and biomedical applications Prog Polym Sci 37 2012 106 126
93. A. Moshaverinia, C. Chen, and K. Akiyama et al. Alginate hydrogel as a promising scaffold for dental-derived stem cells: an in vitro study J Mater Sci Mater Med 23 2012 3041 3051
94. K. Dobie, G. Smith, and A. Sloan et al. Effects of alginate hydrogels and TGF-β1 on human dental pulp repair in vitro Connect Tissue Res 43 2002 387 390
95. C.A. Holladay, A.M. Duffy, and X. Chen et al. Recovery of cardiac function mediated by MSC and interleukin-10 plasmid functionalised scaffold Biomaterials 33 2012 1303 1314
96. T.S. Lakshmi, N. Shanmugasundaram, and S. Shanmuganathan et al. Efficacy of desulfated heparin mitigating inflammation in rat burn wound model J Biomed Mater Res B Appl Biomater 97 2011 215 223
97. P.J. Johnson, A. Tatara, and A. Shiu et al. Controlled release of neurotrophin-3 and platelet derived growth factor from fibrin scaffolds containing neural progenitor cells enhances survival and differentiation into neurons in a subacute model of SCI Cell Transplant 19 2010 89
98. P.N. Cheng, J.D. Pham, and J.S. Nowick The supramolecular chemistry of β-sheets J Am Chem Soc 135 2013 5477 5492
99. E.L. Bakota, O. Sensoy, and B. Ozgur et al. Self-assembling multidomain peptide fibers with aromatic cores Biomacromolecules 14 2013 1370 1378
100. K.M. Galler, L. Aulisa, and K.R. Regan et al. Self-assembling multidomain peptide hydrogels: designed susceptibility to enzymatic cleavage allows enhanced cell migration and spreading J Am Chem Soc 132 2010 3217 3223
101. L. Aulisa, H. Dong, and J.D. Hartgerink Self-assembly of multidomain peptides: sequence variation allows control over cross-linking and viscoelasticity Biomacromolecules 10 2009 2694 2698
102. E.L. Bakota, Y. Wang, and F.R. Danesh et al. Injectable multidomain peptide nanofiber hydrogel as a delivery agent for stem cell secretome Biomacromolecules 12 2011 1651 1657
103. H. Dong, S.E. Paramonov, and L. Aulisa et al. Self-assembly of multidomain peptides: balancing molecular frustration controls conformation and nanostructure J Am Chem Soc 129 2007 12468 12472
104. H. Nakahara, H. Misawa, and A. Yoshida et al. Bone repair using a hybrid scaffold of self-assembling peptide PuraMatrix and polyetheretherketone cage in rats Cell Transplant 19 2010 6 7
105. B.N. Cavalcanti, B.D. Zeitlin, and J.E. Nör A hydrogel scaffold that maintains viability and supports differentiation of dental pulp stem cells Dent Mater 29 2013 97 102
106. K.M. Galler, R.N. D'Souza, and J.D. Hartgerink et al. Scaffolds for dental pulp tissue engineering Adv Dent Res 23 2011 333 339
107. K.M. Galler, J.D. Hartgerink, and A.C. Cavender et al. A customized self-assembling peptide hydrogel for dental pulp tissue engineering Tissue Eng Part A 18 2012 176 184
108. K.M. Galler, R.N. D'Souza, and M. Federlin et al. Dentin conditioning codetermines cell fate in regenerative endodontics J Endod 37 2011 1536 1541