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Volumn 7, Issue 4, 2014, Pages 392-418

Radiolabeling of nanoparticles and polymers for PET imaging

Author keywords

Drug delivery; Imaging; Nanomedicine; Nanoparticles; PET; Polymers; Positron emitter; Radiolabeling

Indexed keywords

ARSENIC 72; ARSENIC 74; BROMINE 76; CARBON 11; COPPER 64; COPPER 64 LABELED INORGANIC NANOPARTICLE; COPPER 64 LABELED ORGANIC POLYMER; FLUORINE 18; FLUORINE 18 LABELED ALUMINIUM OXIDE NANOPARTICLE; FLUORINE 18 LABELED CERIUM NANOPARTICLE; FLUORINE 18 LABELED GOLD NANOPARTICLE; FLUORINE 18 LABELED NANOPARTICLE; FLUORINE 18 LABELED POLYMER; FLUORINE 18 LABELED QUANTUM DOT; GALLIUM 68; IODINE 124; NANOPARTICLE; NITROGEN 13; POLYMER; RADIOISOTOPE; UNCLASSIFIED DRUG; YTTRIUM 86; ZIRCONIUM 89;

EID: 84897490714     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph7040392     Document Type: Review
Times cited : (103)

References (67)
  • 1
    • 41649110649 scopus 로고    scopus 로고
    • Imaging in the era of molecular oncology
    • Weissleder, R.; Pittet, M.J. Imaging in the era of molecular oncology. Nature 2008, 452, 580-589.
    • (2008) Nature , vol.452 , pp. 580-589
    • Weissleder, R.1    Pittet, M.J.2
  • 2
    • 33747840618 scopus 로고    scopus 로고
    • Polymer conjugates as anticancer nanomedicines
    • Duncan, R. Polymer conjugates as anticancer nanomedicines. Nat. Rev. Cancer 2006, 6, 688-701.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 688-701
    • Duncan, R.1
  • 4
    • 67650476657 scopus 로고    scopus 로고
    • Radioactive labeling of defined HPMA-based polymeric structures using [18F]FETos for in vivo imaging by positron emission tomography
    • Herth, M.M.; Barz, M.; Moderegger, D.; Allmeroth, M.; Jahn, M.; Thews, O.; Zentel, R.; Rösch, F. Radioactive labeling of defined HPMA-based polymeric structures using [18F]FETos for in vivo imaging by positron emission tomography. Biomacromolecules 2009, 10, 1697-1703.
    • (2009) Biomacromolecules , vol.10 , pp. 1697-1703
    • Herth, M.M.1    Barz, M.2    Moderegger, D.3    Allmeroth, M.4    Jahn, M.5    Thews, O.6    Zentel, R.7    Rösch, F.8
  • 5
    • 0022858683 scopus 로고
    • New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accum
    • Matsumura, Y.; Maeda, H. A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accum. Cancer Res. 1986, 46, 6387-6392.
    • (1986) Cancer Res , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.A.2
  • 6
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • Duncan, R. The dawning era of polymer therapeutics. Nat. Rev. Drug Discov. 2003, 2, 347-360.
    • (2003) Nat. Rev. Drug Discov , vol.2 , pp. 347-360
    • Duncan, R.1
  • 7
    • 33747762229 scopus 로고    scopus 로고
    • Exploiting the enhanced permeability and retention effect for tumor targeting
    • Iyer, A.K.; Khaled, G.; Fang, J.; Maeda, H. Exploiting the enhanced permeability and retention effect for tumor targeting. Drug Discov. Today 2006, 11, 812-818.
    • (2006) Drug Discov. Today , vol.11 , pp. 812-818
    • Iyer, A.K.1    Khaled, G.2    Fang, J.3    Maeda, H.4
  • 9
    • 84875352025 scopus 로고    scopus 로고
    • Emerging role of radiolabeled nanoparticles as an effective diagnostic technique
    • De Barros, A.B.; Tsourkas, A.; Saboury, B.; Cardoso, V.N.; Alavi, A. Emerging role of radiolabeled nanoparticles as an effective diagnostic technique. EJNMMI Res. 2012, 2, 39.
    • (2012) EJNMMI Res , vol.2 , pp. 39
    • de Barros, A.B.1    Tsourkas, A.2    Saboury, B.3    Cardoso, V.N.4    Alavi, A.5
  • 10
    • 84876521475 scopus 로고    scopus 로고
    • Biodistribution of different sized nanoparticles assessed by positron emission tomography: A general strategy for direct activation of metal oxide particles
    • Pérez-Campaña, C.; Gómez-Vallejo, V.; Puigivila, M.; Martín, A.; Calvo-Fernández, T.; Moya, S.E.; Ziolo, R.F.; Reese, T.; Llop, J. Biodistribution of different sized nanoparticles assessed by positron emission tomography: A general strategy for direct activation of metal oxide particles. ACS Nano 2013, 7, 3498-3505.
    • (2013) ACS Nano , vol.7 , pp. 3498-3505
    • Pérez-Campaña, C.1    Gómez-Vallejo, V.2    Puigivila, M.3    Martín, A.4    Calvo-Fernández, T.5    Moya, S.E.6    Ziolo, R.F.7    Reese, T.8    Llop, J.9
  • 12
    • 77956178822 scopus 로고    scopus 로고
    • 72/74As-labeling of HPMA based polymers for long-term in vivo PET imaging
    • Herth, M.M.; Barz, M.; Jahn, M.; Zentel, R.; Rösch, F. 72/74As-labeling of HPMA based polymers for long-term in vivo PET imaging. Bioorg. Med. Chem. Lett. 2010, 20, 5454-5458.
    • (2010) Bioorg. Med. Chem. Lett , vol.20 , pp. 5454-5458
    • Herth, M.M.1    Barz, M.2    Jahn, M.3    Zentel, R.4    Rösch, F.5
  • 13
    • 77951781910 scopus 로고    scopus 로고
    • Iodine-124: A promising positron emitter for organic PET chemistry
    • Koehler, L.; Gagnon, K.; McQuarrie, S.; Wuest, F. Iodine-124: A promising positron emitter for organic PET chemistry. Molecules 2010, 15, 2686-2718.
    • (2010) Molecules , vol.15 , pp. 2686-2718
    • Koehler, L.1    Gagnon, K.2    McQuarrie, S.3    Wuest, F.4
  • 14
    • 77955920036 scopus 로고    scopus 로고
    • In vivo PET imaging and biodistribution of radiolabeled gold nanoshells in rats with tumor xenografts
    • Xie, H.; Wang, Z.J.; Bao, A.; Goins, B.; Phillips, W.T. In vivo PET imaging and biodistribution of radiolabeled gold nanoshells in rats with tumor xenografts. Int. J. Pharm. 2010, 395, 324-330.
    • (2010) Int. J. Pharm , vol.395 , pp. 324-330
    • Xie, H.1    Wang, Z.J.2    Bao, A.3    Goins, B.4    Phillips, W.T.5
  • 17
    • 84858742858 scopus 로고    scopus 로고
    • Synthesis and in vivo evaluation of the biodistribution of a 18F-labeled conjugate gold-nanoparticle-peptide with potential biomedical application
    • Guerrero, S.; Herance, J.R.; Rojas, S.; Mena, J.F.; Gispert, J.D.; Acosta, G.A; Albericio, F.; Kogan, M.J. Synthesis and in vivo evaluation of the biodistribution of a 18F-labeled conjugate gold-nanoparticle-peptide with potential biomedical application. Bioconjug. Chem. 2012, 23, 399-408.
    • (2012) Bioconjug. Chem , vol.23 , pp. 399-408
    • Guerrero, S.1    Herance, J.R.2    Rojas, S.3    Mena, J.F.4    Gispert, J.D.5    Acosta, G.A.6    Albericio, F.7    Kogan, M.J.8
  • 18
    • 84870491286 scopus 로고    scopus 로고
    • In Vivo Biodistribution of Amino-Functionalized Ceria Nanoparticles in Rats Using Positron Emission Tomography
    • Rojas, S.; Gispert, J.D.; Abad, S.; Buaki-Sogo, M.; Victor, V.M.; Garcia, H.; Herance, J.R. In Vivo Biodistribution of Amino-Functionalized Ceria Nanoparticles in Rats Using Positron Emission Tomography. Mol. Pharm. 2012, 9, 3543-3550.
    • (2012) Mol. Pharm , vol.9 , pp. 3543-3550
    • Rojas, S.1    Gispert, J.D.2    Abad, S.3    Buaki-Sogo, M.4    Victor, V.M.5    Garcia, H.6    Herance, J.R.7
  • 20
    • 84867286613 scopus 로고    scopus 로고
    • Tracing nanoparticles in vivo: A new general synthesis of positron emitting metal oxide nanoparticles by proton beam activation
    • Pérez-Campaña, C.; Gómez-Vallejo, V.; Martin, A.; San Sebastián, E.; Moya, S.E.; Reese, T.; Ziolo, R.F.; Llop, J. Tracing nanoparticles in vivo: A new general synthesis of positron emitting metal oxide nanoparticles by proton beam activation. Analyst 2012, 137, 4902-4906.
    • (2012) Analyst , vol.137 , pp. 4902-4906
    • Pérez-Campaña, C.1    Gómez-Vallejo, V.2    Martin, A.3    San, S.E.4    Moya, S.E.5    Reese, T.6    Ziolo, R.F.7    Llop, J.8
  • 22
    • 84884866696 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticle pretargeting for PET imaging based on a rapid bioorthogonal reaction in a living body
    • Lee, S.B.; Kim, H.L.; Jeong, H.-J.; Lim, S.T.; Sohn, M.-H.; Kim, D.W. Mesoporous silica nanoparticle pretargeting for PET imaging based on a rapid bioorthogonal reaction in a living body. Angew. Chem. Int. Ed. Engl. 2013, 52, 10549-10552.
    • (2013) Angew. Chem. Int. Ed. Engl , vol.52 , pp. 10549-10552
    • Lee, S.B.1    Kim, H.L.2    Jeong, H.-J.3    Lim, S.T.4    Sohn, M.-H.5    Kim, D.W.6
  • 23
    • 79960250597 scopus 로고    scopus 로고
    • Modifying the body distribution of HPMA-based copolymers by molecular weight and aggregate formation
    • Allmeroth, M.; Moderegger, D.; Biesalski, B.; Koynov, K.; Rösch, F.; Thews, O.; Zentel, R. Modifying the body distribution of HPMA-based copolymers by molecular weight and aggregate formation. Biomacromolecules 2011, 12, 2841-2849.
    • (2011) Biomacromolecules , vol.12 , pp. 2841-2849
    • Allmeroth, M.1    Moderegger, D.2    Biesalski, B.3    Koynov, K.4    Rösch, F.5    Thews, O.6    Zentel, R.7
  • 24
    • 84883550358 scopus 로고    scopus 로고
    • PEGylation of HPMA-based block copolymers enhances tumor accumulation in vivo: A quantitative study using radiolabeling and positron emission tomography
    • Allmeroth, M.; Moderegger, D.; Gündel, D.; Buchholz, H.-G.; Mohr, N.; Koynov, K.; Rösch, F.; Thews, O.; Zentel, R. PEGylation of HPMA-based block copolymers enhances tumor accumulation in vivo: A quantitative study using radiolabeling and positron emission tomography. J. Control. Release 2013, 172, 77-85.
    • (2013) J. Control. Release , vol.172 , pp. 77-85
    • Allmeroth, M.1    Moderegger, D.2    Gündel, D.3    Buchholz, H.-G.4    Mohr, N.5    Koynov, K.6    Rösch, F.7    Thews, O.8    Zentel, R.9
  • 25
    • 77956048487 scopus 로고    scopus 로고
    • Low temperature synthesis of ZnS and CdZnS shells on CdSe quantum dots
    • Zhu, H.; Prakash, A.; Benoit, D.N.; Jones, C.J.; Colvin, V.L. Low temperature synthesis of ZnS and CdZnS shells on CdSe quantum dots. Nanotechnology 2010, 21, 255604.
    • (2010) Nanotechnology , vol.21 , pp. 255604
    • Zhu, H.1    Prakash, A.2    Benoit, D.N.3    Jones, C.J.4    Colvin, V.L.5
  • 26
    • 80855143767 scopus 로고    scopus 로고
    • Facile synthesis of highly luminescent CdSe/CdxZn1-xS quantum dots with widely tunable emission spectra
    • Yang, P.; Ando, M.; Murase, N. Facile synthesis of highly luminescent CdSe/CdxZn1-xS quantum dots with widely tunable emission spectra. Colloids Surfaces A Physicochem. Eng. Asp. 2011, 390, 207-211.
    • (2011) Colloids Surfaces a Physicochem. Eng. Asp , vol.390 , pp. 207-211
    • Yang, P.1    Ando, M.2    Murase, N.3
  • 27
    • 20144364601 scopus 로고    scopus 로고
    • 1-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: Design, synthesis, and radiosynthesis of a new [18F]fluoropyridine-based maleimide reagent for the labeling of peptides and proteins
    • De Bruin, B.; Kuhnast, B.; Hinnen, F.; Yaouancq, L.; Amessou, M.; Johannes, L.; Samson, A.; Boisgard, R.; Tavitian, B.; Dollé, F. 1-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: Design, synthesis, and radiosynthesis of a new [18F]fluoropyridine-based maleimide reagent for the labeling of peptides and proteins. Bioconjug. Chem. 2005, 16, 406-420.
    • (2005) Bioconjug. Chem , vol.16 , pp. 406-420
    • de Bruin, B.1    Kuhnast, B.2    Hinnen, F.3    Yaouancq, L.4    Amessou, M.5    Johannes, L.6    Samson, A.7    Boisgard, R.8    Tavitian, B.9    Dollé, F.10
  • 30
    • 75749117588 scopus 로고    scopus 로고
    • Molecular imaging of HPMA copolymers: Visualizing drug delivery in cell, mouse and man
    • Lu, Z.-R. Molecular imaging of HPMA copolymers: Visualizing drug delivery in cell, mouse and man. Adv. Drug Deliv. Rev. 2010, 62, 246-257.
    • (2010) Adv. Drug Deliv. Rev , vol.62 , pp. 246-257
    • Lu Z.-R1
  • 31
    • 84873273856 scopus 로고    scopus 로고
    • Polymer therapeutics-prospects for 21st century: The end of the beginning
    • Duncan, R.; Vicent, M.J. Polymer therapeutics-prospects for 21st century: The end of the beginning. Adv. Drug Deliv. Rev. 2013, 65, 60-70.
    • (2013) Adv. Drug Deliv. Rev , vol.65 , pp. 60-70
    • Duncan, R.1    Vicent, M.J.2
  • 32
    • 84878665586 scopus 로고    scopus 로고
    • Facile method to radiolabel glycol chitosan nanoparticles with (64)Cu via copper-free click chemistry for MicroPET imaging
    • Lee, D.-E.; Na, J.H.; Lee, S.; Kang, C.M.; Kim, H.N.; Han, S.J.; Kim, H.; Choe, Y.S.; Jung, K.-H.; Lee, K.C., et al. Facile method to radiolabel glycol chitosan nanoparticles with (64)Cu via copper-free click chemistry for MicroPET imaging. Mol. Pharm. 2013, 10, 2190-2198.
    • (2013) Mol. Pharm , vol.10 , pp. 2190-2198
    • Lee, D.-E.1    Na, J.H.2    Lee, S.3    Kang, C.M.4    Kim, H.N.5    Han, S.J.6    Kim, H.7    Choe, Y.S.8    Jung, K.-H.9    Lee, K.C.10
  • 33
    • 84859967416 scopus 로고    scopus 로고
    • Nanoparticles labeled with positron emitting nuclides: Advantages, methods, and applications
    • Liu, Y.; Welch, M.J. Nanoparticles labeled with positron emitting nuclides: Advantages, methods, and applications. Bioconjug. Chem. 2012, 23, 671-682.
    • (2012) Bioconjug. Chem , vol.23 , pp. 671-682
    • Liu, Y.1    Welch, M.J.2
  • 35
    • 7644219830 scopus 로고    scopus 로고
    • Molecular imaging with copper-64
    • Smith, S.V. Molecular imaging with copper-64. J. Inorg. Biochem. 2004, 98, 1874-1901.
    • (2004) J. Inorg. Biochem , vol.98 , pp. 1874-1901
    • Smith, S.V.1
  • 36
    • 84897510032 scopus 로고    scopus 로고
    • 5th ed.; de Gruyter: Berlin, Germany
    • Riedel, E. Anorganische Chemie, 5th ed.; de Gruyter: Berlin, Germany, 2002; p. 736.
    • Anorganische Chemie , vol.2002 , pp. 736
    • Riedel, E.1
  • 37
    • 25844495323 scopus 로고    scopus 로고
    • An assessment of the effects of shell cross-linked nanoparticle size, core composition, and surface PEGylation on in vivo biodistribution
    • Sun, X.; Rossin, R.; Turner, J.L.; Becker, M.L.; Joralemon, M.J.; Welch, M.J.; Wooley, K.L. An assessment of the effects of shell cross-linked nanoparticle size, core composition, and surface PEGylation on in vivo biodistribution. Biomacromolecules 2005, 6, 2541-2554.
    • (2005) Biomacromolecules , vol.6 , pp. 2541-2554
    • Sun, X.1    Rossin, R.2    Turner, J.L.3    Becker, M.L.4    Joralemon, M.J.5    Welch, M.J.6    Wooley, K.L.7
  • 38
    • 33750377517 scopus 로고    scopus 로고
    • 64Cu-labeled Abegrin, a humanized monoclonal antibody against integrin alpha v beta 3
    • 64Cu-labeled Abegrin, a humanized monoclonal antibody against integrin alpha v beta 3. Cancer Res. 2006, 66, 9673-9681.
    • (2006) Cancer Res , vol.66 , pp. 9673-9681
    • Cai, W.1    Wu, Y.2    Chen, K.3    Cao, Q.4    Tice, D.A.5    Chen, X.6
  • 44
    • 84874080659 scopus 로고    scopus 로고
    • Nanoparticle PET/CT imaging of natriuretic peptide clearance receptor in prostate cancer
    • Pressly, E.D.; Pierce, R.A; Connal, L.A; Hawker, C.J.; Liu, Y. Nanoparticle PET/CT imaging of natriuretic peptide clearance receptor in prostate cancer. Bioconjug. Chem. 2013, 24, 196-204.
    • (2013) Bioconjug. Chem , vol.24 , pp. 196-204
    • Pressly, E.D.1    Pierce, R.A.2    Connal, L.A.3    Hawker, C.J.4    Liu, Y.5
  • 48
    • 79954611164 scopus 로고    scopus 로고
    • PET Imaging and Biodistribution of Silicon Quantum Dots in Mice
    • Tu, C.; Ma, X.; House, A.; Kauzlarich, S.M.; Louie, A.Y. PET Imaging and Biodistribution of Silicon Quantum Dots in Mice. ACS Med. Chem. Lett. 2011, 2, 285-288.
    • (2011) ACS Med. Chem. Lett , vol.2 , pp. 285-288
    • Tu, C.1    Ma, X.2    House, A.3    Kauzlarich, S.M.4    Louie, A.Y.5
  • 50
    • 77951276860 scopus 로고    scopus 로고
    • In vivo evaluation of (64)Cu-labeled magnetic nanoparticles as a dual-modality PET/MR imaging agent
    • Glaus, C.; Rossin, R.; Welch, M.J.; Bao, G. In vivo evaluation of (64)Cu-labeled magnetic nanoparticles as a dual-modality PET/MR imaging agent. Bioconjug. Chem. 2010, 21, 715-722.
    • (2010) Bioconjug. Chem , vol.21 , pp. 715-722
    • Glaus, C.1    Rossin, R.2    Welch, M.J.3    Bao, G.4
  • 52
    • 70350724584 scopus 로고    scopus 로고
    • The advantages of nanoparticles for PET
    • Welch, M.J.; Hawker, C.J.; Wooley, K.L. The advantages of nanoparticles for PET. J. Nucl. Med. 2009, 50, 1743-1746.
    • (2009) J. Nucl. Med , vol.50 , pp. 1743-1746
    • Welch, M.J.1    Hawker, C.J.2    Wooley, K.L.3
  • 54
    • 75149190916 scopus 로고    scopus 로고
    • Modular strategies for PET imaging agents
    • Hooker, J.M. Modular strategies for PET imaging agents. Curr. Opin. Chem. Biol. 2010, 14, 105-111.
    • (2010) Curr. Opin. Chem. Biol , vol.14 , pp. 105-111
    • Hooker, J.M.1
  • 55
    • 84863538680 scopus 로고    scopus 로고
    • Maturation of a key resource-The germanium-68/gallium-68 generator: Development and new insights
    • Roesch, F. Maturation of a key resource-The germanium-68/gallium-68 generator: Development and new insights. Curr. Radiopharm. 2012, 5, 202-211.
    • (2012) Curr. Radiopharm , vol.5 , pp. 202-211
    • Roesch, F.1
  • 57
    • 84881660238 scopus 로고    scopus 로고
    • Hybrid PET/MR imaging of tumors using an oleanolic acid-conjugated nanoparticle
    • Kim, S.-M.; Chae, M.K.; Yim, M.S.; Jeong, I.H.; Cho, J.; Lee, C.; Ryu, E.K. Hybrid PET/MR imaging of tumors using an oleanolic acid-conjugated nanoparticle. Biomaterials 2013, 34, 8114-8121.
    • (2013) Biomaterials , vol.34 , pp. 8114-8121
    • Kim, S.-M.1    Chae, M.K.2    Yim, M.S.3    Jeong, I.H.4    Cho, J.5    Lee, C.6    Ryu, E.K.7
  • 58
    • 77149167302 scopus 로고    scopus 로고
    • Modification of aminosilanized superparamagnetic nanoparticles: Feasibility of multimodal detection using 3T MRI, small animal PET, and fluorescence imaging
    • Stelter, L.; Pinkernelle, J.G.; Michel, R.; Schwartländer, R.; Raschzok, N.; Morgul, M.H.; Koch, M.; Denecke, T.; Ruf, J.; Bäumler, H., et al. Modification of aminosilanized superparamagnetic nanoparticles: Feasibility of multimodal detection using 3T MRI, small animal PET, and fluorescence imaging. Mol. Imaging Biol. 2010, 12, 25-34.
    • (2010) Mol. Imaging Biol , vol.12 , pp. 25-34
    • Stelter, L.1    Pinkernelle, J.G.2    Michel, R.3    Schwartländer, R.4    Raschzok, N.5    Morgul, M.H.6    Koch, M.7    Denecke, T.8    Ruf, J.9    Bäumler, H.10
  • 60
    • 80053197499 scopus 로고    scopus 로고
    • Development of novel positron emitters for medical applications: Nuclear and radiochemical aspects
    • Qaim, S.M. Development of novel positron emitters for medical applications: Nuclear and radiochemical aspects. Radiochim. Acta 2011, 99, 611-625.
    • (2011) Radiochim. Acta , vol.99 , pp. 611-625
    • Qaim, S.M.1
  • 61
    • 84866431013 scopus 로고    scopus 로고
    • The present and future of medical radionuclide production
    • Qaim, S.M. The present and future of medical radionuclide production. Radiochim. Acta 2012, 100, 635-651.
    • (2012) Radiochim. Acta , vol.100 , pp. 635-651
    • Qaim, S.M.1
  • 62
    • 79951698842 scopus 로고    scopus 로고
    • Separation and purification of no-carrier-added arsenic from bulk amounts of germanium for use in radiopharmaceutical labelling
    • Jahn, M.; Radchenko, V.; Filosofov, D.V.; Hauser, H.; Eisenhut, M.; Rösch, F.; Jennewein, M. Separation and purification of no-carrier-added arsenic from bulk amounts of germanium for use in radiopharmaceutical labelling. Radiochim. Acta 2010, 98, 807-812.
    • (2010) Radiochim. Acta , vol.98 , pp. 807-812
    • Jahn, M.1    Radchenko, V.2    Filosofov, D.V.3    Hauser, H.4    Eisenhut, M.5    Rösch, F.6    Jennewein, M.7


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