CRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging

Biomaterials

Volumn 32, Issue 17, 2011, Pages 4151-4160

  Yang, Xiaoqiang ^a   Hong, Hao ^b,c   Grailer, Jamison J ^d   Rowland, Ian J ^c   Javadi, Alireza ^b   Hurley, Samuel A ^c   Xiao, Yuling ^b   Yang, Yunan ^b,c   Zhang, Yin ^b,c   Nickles, Robert J ^b,c   Cai, Weibo ^b,c   Steeber, Douglas A ^d   Gong, Shaoqin ^b  

^a University of Wisconsin Milwaukee   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

Author keywords

Drug delivery; Magnetic resonance imaging (MRI); Nanomedicine; Positron emission tomography (PET); Superparamagnetic iron oxide

Indexed keywords

ANTI-CANCER DRUG DELIVERY; ANTICANCER DRUG; ARG GLY ASPS; CELLULAR UPTAKE; DUAL-MODALITY IMAGING; EX-VIVO; FUNCTIONALIZED; IN-VITRO; INTEGRINS; MACROCYCLICS; MRI CONTRAST AGENTS; NANOCARRIERS; NANOMEDICINES; NON-INVASIVE; PH SENSITIVE; POSITRON EMISSION; QUANTITATIVE PET; RELAXIVITY; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES; SUPERPARAMAGNETIC IRON OXIDES; TARGETED DRUG DELIVERY; TRIAZACYCLONONANE; TUMOR ACCUMULATION;

DRUG DELIVERY; ELECTRONS; IRON OXIDES; MAGNETIC RESONANCE IMAGING; MEDICAL NANOTECHNOLOGY; POSITRONS; RESONANCE; SUPERPARAMAGNETISM; TUMORS;

POSITRON EMISSION TOMOGRAPHY;

AMINO ACID; COPPER 64; CYCLO(ARGINYLGLYCYLASPARTYLDEXTROPHENYLALANYLCYSTEINE); MACROCYCLIC 1,4,7 TRIAZACYCLONONANE N,N'N'' TRIACETIC ACID; MACROCYCLIC COMPOUND; NANOCARRIER; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; FEMALE; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PH; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CONTRAST MEDIA; DEXTRANS; DIAGNOSTIC IMAGING; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; INTEGRIN ALPHAVBETA3; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MALONATES; MICE; MICE, NUDE; MODELS, ANIMAL; NANOMEDICINE; NEOPLASMS; PARTICLE SIZE; PEPTIDES, CYCLIC; POSITRON-EMISSION TOMOGRAPHY; TISSUE DISTRIBUTION;

EID: 79953290956     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.02.006     Document Type: Article

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