Selective expansion of chimeric antigen receptor-targeted T-cells with potent effector function using interleukin-4

Journal of Biological Chemistry

Volumn 285, Issue 33, 2010, Pages 25538-25544

  Wilkie, Scott ^a   Burbridge, Sophie E ^a   Chiapero Stanke, Laura ^a   Pereira, Ana C P ^a   Cleary, Siobhán ^a   Van Der Stegen, Sjoukje J C ^a   Spicer, James F ^a   Davies, David M ^a   Maher, John ^a,b,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE LONDON NHS FOUNDATION TRUST   (United Kingdom)

^c KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN RECEPTORS; BLOOD VOLUMES; CLINICAL TRIAL; CYTOKINE RECEPTOR; CYTOKINES; ECTODOMAIN; ENHANCED T; EX VIVO EXPANSION; EX-VIVO; HUMAN T CELLS; IN-VITRO; INTERLEUKIN-4; MUTEINS; PATHOPHYSIOLOGIC; POLYCLONAL; PRECLINICAL STUDIES; PROOF OF PRINCIPLES; T CELLS; TRANSMEMBRANES;

ANTIGENS; CELLS; EXPANSION; PHOSPHORYLATION; TUMORS;

CELL CULTURE;

INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; LYMPHOCYTE ANTIGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN 1; STAT3 PROTEIN; STAT5 PROTEIN;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL SPECIFICITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-15; INTERLEUKIN-2; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MICE; PHOSPHORYLATION; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN-4; RECOMBINANT FUSION PROTEINS; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES;

EID: 77955503406     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.127951     Document Type: Article

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