Structural Insights into E. coli Porphobilinogen Deaminase during Synthesis and Exit of 1-Hydroxymethylbilane

PLoS Computational Biology

Volumn 10, Issue 3, 2014, Pages

  Bung, Navneet ^a   Pradhan, Meenakshi ^a   Srinivasan, Harini ^a   Bulusu, Gopalakrishnan ^a  

^a TATA CONSULTANCY SERVICES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; BIOCHEMISTRY; CHAINS; ESCHERICHIA COLI; MOLECULAR DYNAMICS; STRUCTURE (COMPOSITION);

ACTIVE SITE; CATALYSE; CATALYTIC CYCLES; COFACTORS; DIPYRROMETHANES; E. COLI; PORPHOBILINOGEN; PYRROLE RING; STRUCTURAL INSIGHTS; TETRAPYRROLES;

PROTEINS;

1 HYDROXYMETHYLBILANE; PORPHOBILINOGEN; PORPHOBILINOGEN DEAMINASE; TETRAPYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BIOSYNTHESIS; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PROTEIN DOMAIN; PROTEIN FOLDING; RESIDUE ANALYSIS; RNA TRANSLATION; STRUCTURE ANALYSIS;

CATALYSIS; CATALYTIC DOMAIN; COMPUTATIONAL BIOLOGY; DIFFUSION; ESCHERICHIA COLI; HEME; HYDROXYMETHYLBILANE SYNTHASE; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; MUTATION; PYRROLES; UROPORPHYRINOGENS;

EID: 84897468183     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003484     Document Type: Article

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