-
1
-
-
84873956600
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease GOLD executive summary
-
Vestbo J, Hurd SS, Agusti A.G., et al Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease GOLD Executive Summary. Am J Respir Crit Care Med 2013; 187: 347-365.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 347-365
-
-
Vestbo, J.1
Hurd, S.S.2
Agusti, A.G.3
-
2
-
-
0031001720
-
Alternative projections of mortality and disability by cause 1990-2020: Global burden of disease study
-
Murray CJ, Lopez AD Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 1997; 349: 1498-1504.
-
(1997)
Lancet
, vol.349
, pp. 1498-1504
-
-
Murray, C.J.1
Lopez, A.D.2
-
3
-
-
80052706801
-
New insights into the immunology of chronic obstructive pulmonary disease
-
Brusselle GG, Joos GF, Bracke KR New insights into the immunology of chronic obstructive pulmonary disease. Lancet 2011; 378: 1015-1026.
-
(2011)
Lancet
, vol.378
, pp. 1015-1026
-
-
Brusselle, G.G.1
Joos, G.F.2
Bracke, K.R.3
-
4
-
-
33745905620
-
Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema
-
Demedts I, Demoor T, Bracke K.R., et al Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema. Respir Res 2006; 7: 53.
-
(2006)
Respir Res
, vol.7
, pp. 53
-
-
Demedts, I.1
Demoor, T.2
Bracke, K.R.3
-
5
-
-
43349158916
-
New concepts in the pathobiology of chronic obstructive pulmonary disease
-
Kim V, Rogers TJ, Criner GJ New concepts in the pathobiology of chronic obstructive pulmonary disease. Proc Am Thorac Soc 2008; 5: 478-485.
-
(2008)
Proc Am Thorac Soc
, vol.5
, pp. 478-485
-
-
Kim, V.1
Rogers, T.J.2
Criner, G.J.3
-
6
-
-
0034604110
-
Role of transforming growth factor-β in human disease
-
Blobe GC, Schiemann WP, Lodish HF Role of transforming growth factor-β in human disease. N Engl J Med 2000; 342: 1350-1358.
-
(2000)
N Engl J Med
, vol.342
, pp. 1350-1358
-
-
Blobe, G.C.1
Schiemann, W.P.2
Lodish, H.F.3
-
7
-
-
0032416948
-
Transforming growth factor-β1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary disease
-
Boer WI, van Schadewijk A, Sont JK, et al Transforming growth factor-β1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998; 158: 1951-1957.
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 1951-1957
-
-
Boer, W.I.1
Van Schadewijk, A.2
Sont, J.K.3
-
8
-
-
33646164362
-
Transforming growth factor-β regulation of immune responses
-
Li MO, Wan YY, Sanjabi S, et al Transforming growth factor-β regulation of immune responses. Annu Rev Immunol 2006; 24: 99-146.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 99-146
-
-
Li, M.O.1
Wan, Y.Y.2
Sanjabi, S.3
-
9
-
-
17044453955
-
Increased expression of transforming growth factor-β1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (COPD)
-
Takizawa H, Tanaka M, Takami K., et al Increased expression of transforming growth factor-β1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (COPD). Am J Respir Crit Care Med 2001; 163: 1476-1483.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 1476-1483
-
-
Takizawa, H.1
Tanaka, M.2
Takami, K.3
-
11
-
-
2342488852
-
New insights into TGF-β-smad signalling
-
Dijke P, Hill CS New insights into TGF-β-Smad signalling. Trends Biochem Sci 2004; 29: 265-273.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 265-273
-
-
Dijke, P.1
Hill, C.S.2
-
12
-
-
13944271697
-
Antagonists of activin signaling: Mechanisms and potential biological applications
-
Harrison CA, Gray PC, Vale W.W., et al Antagonists of activin signaling: mechanisms and potential biological applications. Trends Endocrinol Metab 2005; 16: 73-78.
-
(2005)
Trends Endocrinol Metab
, vol.16
, pp. 73-78
-
-
Harrison, C.A.1
Gray, P.C.2
Vale, W.W.3
-
13
-
-
1542360500
-
Bone morphogenetic protein (BMP) ligands and receptors in bovine ovarian follicle cells: Actions of BMP-4,-6 and-7 on granulosa cells and differential modulation of smad-1 phosphorylation by follistatin
-
Glister C, Kemp CF, Knight PG Bone morphogenetic protein (BMP) ligands and receptors in bovine ovarian follicle cells: actions of BMP-4,-6 and-7 on granulosa cells and differential modulation of Smad-1 phosphorylation by follistatin. Reproduction 2004; 127: 239-254.
-
(2004)
Reproduction
, vol.127
, pp. 239-254
-
-
Glister, C.1
Kemp, C.F.2
Knight, P.G.3
-
14
-
-
42049113862
-
Follistatin antagonizes transforming growth factor-β3-induced epithelialmesenchymal transition in vitro: Implications for murine palatal development supported by microarray analysis
-
Nogai H, Rosowski M, Grun J., et al Follistatin antagonizes transforming growth factor-β3-induced epithelialmesenchymal transition in vitro: implications for murine palatal development supported by microarray analysis. Differentiation 2008; 76: 404-416.
-
(2008)
Differentiation
, vol.76
, pp. 404-416
-
-
Nogai, H.1
Rosowski, M.2
Grun, J.3
-
15
-
-
33745645604
-
Follistatin is a candidate endogenous negative regulator of activin A in experimental allergic asthma
-
Hardy CL, O'Connor AE, Yao J, et al Follistatin is a candidate endogenous negative regulator of activin A in experimental allergic asthma. Clin Exp Allergy 2006; 36: 941-950.
-
(2006)
Clin Exp Allergy
, vol.36
, pp. 941-950
-
-
Hardy, C.L.1
O'Connor, A.E.2
Yao, J.3
-
16
-
-
29544448270
-
Activin A is an acute allergen-responsive cytokine and provides a link to TGF-β-mediated airway remodeling in asthma
-
Karagiannidis C, Hense G, Martin C., et al Activin A is an acute allergen-responsive cytokine and provides a link to TGF-β-mediated airway remodeling in asthma. J Allergy Clin Immunol 2006; 117: 111-118.
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. 111-118
-
-
Karagiannidis, C.1
Hense, G.2
Martin, C.3
-
17
-
-
69549092367
-
Activin and transforming growth factor-beta signaling pathways are activated after allergen challenge in mild asthma
-
Kariyawasam HH, Pegorier S, Barkans J., et al Activin and transforming growth factor-beta signaling pathways are activated after allergen challenge in mild asthma. J Allergy Clin Immunol 2009; 124: 454-462.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 454-462
-
-
Kariyawasam, H.H.1
Pegorier, S.2
Barkans, J.3
-
18
-
-
0034922101
-
Activation of the TGF-β/activin-smad2 pathway during allergic airway inflammation
-
Rosendahl A, Checchin D, Fehniger T.E., et al Activation of the TGF-β/activin-Smad2 pathway during allergic airway inflammation. Am J Respir Cell Mol Biol 2001; 25: 60-68.
-
(2001)
Am J Respir Cell Mol Biol
, vol.25
, pp. 60-68
-
-
Rosendahl, A.1
Checchin, D.2
Fehniger, T.E.3
-
19
-
-
84857397930
-
Activin - A overexpression in the murine lung causes pathology that simulates acute respiratory distress syndrome
-
Apostolou E, Stavropoulos A, Sountoulidis A., et al Activin-A overexpression in the murine lung causes pathology that simulates acute respiratory distress syndrome. Am J Respir Crit Care Med 2012; 185: 382-391.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 382-391
-
-
Apostolou, E.1
Stavropoulos, A.2
Sountoulidis, A.3
-
20
-
-
0030091573
-
Expression of immunoreactive activin a protein in remodeling lesions associated with interstitial pulmonary fibrosis
-
Matsuse T, Ikegami A, Ohga E., et al Expression of immunoreactive activin a protein in remodeling lesions associated with interstitial pulmonary fibrosis. Am J Pathol 1996; 148: 707-713.
-
(1996)
Am J Pathol
, vol.148
, pp. 707-713
-
-
Matsuse, T.1
Ikegami, A.2
Ohga, E.3
-
21
-
-
77954630963
-
Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD
-
Pottelberge GR, Bracke KR, Demedts I.K., et al Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD. Respir Res 2010; 11: 35.
-
(2010)
Respir Res
, vol.11
, pp. 35
-
-
Pottelberge, G.R.1
Bracke, K.R.2
Demedts, I.K.3
-
22
-
-
0033850269
-
Regulation of secretory leukocyte proteinase inhibitor (SLPI) production by human bronchial epithelial cells: Increase of cell-associated SLPI by neutrophil elastase
-
Wetering S, van der Linden AC, van Sterkenburg MAJA, et al. Regulation of secretory leukocyte proteinase inhibitor (SLPI) production by human bronchial epithelial cells: increase of cell-associated SLPI by neutrophil elastase. J Investig Med 2000; 48: 359-366.
-
(2000)
J Investig Med
, vol.48
, pp. 359-366
-
-
Wetering, S.1
Van Der Linden, A.C.2
Van Sterkenburg, M.A.J.A.3
-
23
-
-
79955368069
-
IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides
-
Zuyderduyn S, Ninaber D, Schrumpf J., et al IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides. Respir Res 2011; 12: 59.
-
(2011)
Respir Res
, vol.12
, pp. 59
-
-
Zuyderduyn, S.1
Ninaber, D.2
Schrumpf, J.3
-
24
-
-
4444340696
-
Exposure of differentiated airway epithelial cells to volatile smoke in vitro
-
Beisswenger C, Platz J, Seifart C., et al Exposure of differentiated airway epithelial cells to volatile smoke in vitro. Respiration 2004; 71: 402-409.
-
(2004)
Respiration
, vol.71
, pp. 402-409
-
-
Beisswenger, C.1
Platz, J.2
Seifart, C.3
-
25
-
-
23144466310
-
Time course of cigarette smoke-induced pulmonary inflammation in mice
-
D'hulst A.I., Vermaelen KY, Brusselle G.G., et al Time course of cigarette smoke-induced pulmonary inflammation in mice. Eur Respir J 2005; 26: 204-213.
-
(2005)
Eur Respir J
, vol.26
, pp. 204-213
-
-
D'hulst, A.I.1
Vermaelen, K.Y.2
Brusselle, G.G.3
-
27
-
-
0343145719
-
Activin A: A novel player and inflammatory marker in inflammatory bowel disease?
-
Hubner G. Activin A: A novel player and inflammatory marker in inflammatory bowel disease? Lab Invest 1997; 77: 311-318.
-
(1997)
Lab Invest
, vol.77
, pp. 311-318
-
-
Hubner, G.1
-
28
-
-
0141676445
-
Activin a induces cell proliferation of fibroblast-like synoviocytes in rheumatoid arthritis
-
Ota F. Activin a induces cell proliferation of fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Rheum 2003; 48: 2442-2449.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2442-2449
-
-
Ota, F.1
-
29
-
-
0034605095
-
Inhibition of E-selectin gene expression by transforming growth factor-β in endothelial cells involves coactivator integration of smad and nuclear factor KB-mediated signals
-
DiChiara MR, Kiely JM, Gimbrone M.A., et al Inhibition of E-selectin gene expression by transforming growth factor-β in endothelial cells involves coactivator integration of Smad and nuclear factor KB-mediated signals. J Exp Med 2000; 192: 695-704.
-
(2000)
J Exp Med
, vol.192
, pp. 695-704
-
-
DiChiara, M.R.1
Kiely, J.M.2
Gimbrone, M.A.3
-
30
-
-
34447556625
-
Human bronchial epithelial cell transcriptome: Gene expression changes following acute exposure to whole cigarette smoke in vitro
-
Maunders H, Patwardhan S, Phillips J., et al Human bronchial epithelial cell transcriptome: gene expression changes following acute exposure to whole cigarette smoke in vitro. Am J Physiol Lung Cell Mol Physiol 2007; 292: L1248-L1256.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Maunders, H.1
Patwardhan, S.2
Phillips, J.3
-
31
-
-
42749091669
-
Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling
-
Leigh R, Oyelusi W, Wiehler S., et al Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling. J Allergy Clin Immunol 2008; 121: 1238-1245.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 1238-1245
-
-
Leigh, R.1
Oyelusi, W.2
Wiehler, S.3
-
32
-
-
0032014542
-
CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease
-
Saetta M, Di Stefano A, Turato G, et al CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998; 157: 822-826.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 822-826
-
-
Saetta, M.1
Di Stefano, A.2
Turato, G.3
-
33
-
-
77951193253
-
Increased T-regulatory cells in lungs and draining lymph nodes in a murine model of COPD
-
Demoor T, Bracke KR, Joos G.F., et al Increased T-regulatory cells in lungs and draining lymph nodes in a murine model of COPD. Eur Respir J 2010; 35: 688-689.
-
(2010)
Eur Respir J
, vol.35
, pp. 688-689
-
-
Demoor, T.1
Bracke, K.R.2
Joos, G.F.3
-
34
-
-
24944437072
-
Attenuation of bleomycin-induced pulmonary fibrosis by follistatin
-
Aoki F, Kurabayashi M, Hasegawa Y., et al Attenuation of bleomycin-induced pulmonary fibrosis by follistatin. Am J Respir Crit Care Med 2005; 172: 713-720.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 713-720
-
-
Aoki, F.1
Kurabayashi, M.2
Hasegawa, Y.3
-
35
-
-
84857397930
-
Activin - A overexpression in the murine lung causes pathology that simulates acute respiratory distress syndrome
-
Apostolou E, Stavropoulos A, Sountoulidis A., et al Activin-A overexpression in the murine lung causes pathology that simulates acute respiratory distress syndrome. Am J Respir Crit Care Med 2012; 185: 382-391.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 382-391
-
-
Apostolou, E.1
Stavropoulos, A.2
Sountoulidis, A.3
-
36
-
-
68149162210
-
Activin - A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease
-
Semitekolou M, Alissafi T, Aggelakopoulou M., et al Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease. J Exp Med 2009; 206: 1769-1785.
-
(2009)
J Exp Med
, vol.206
, pp. 1769-1785
-
-
Semitekolou, M.1
Alissafi, T.2
Aggelakopoulou, M.3
-
37
-
-
63749105935
-
Activin and related proteins in inflammation: Not just interested bystanders
-
Phillips DJ, de Kretser DM, Hedger MP Activin and related proteins in inflammation: not just interested bystanders. Cytokine Growth Factor Rev 2009; 20: 153-164.
-
(2009)
Cytokine Growth Factor Rev
, vol.20
, pp. 153-164
-
-
Phillips, D.J.1
De Kretser, D.M.2
Hedger, M.P.3
-
38
-
-
79955958973
-
Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers
-
Sierra-Filardi E., Puig-Kröger A, Blanco FJ, et al. Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers. Blood 2011; 117: 5092-5101.
-
(2011)
Blood
, vol.117
, pp. 5092-5101
-
-
Sierra-Filardi, E.1
Puig-Kröger, A.2
Blanco, F.J.3
-
39
-
-
65249138364
-
Activin A promotes the TGF-β-induced conversion of CD4+CD25-T cells into foxp3+ induced regulatory T cells
-
Huber S, Stahl FR, Schrader J, et al. Activin A promotes the TGF-β-induced conversion of CD4+CD25-T Cells into Foxp3+ induced regulatory T cells. J Immunol 2009; 182: 4633-4640.
-
(2009)
J Immunol
, vol.182
, pp. 4633-4640
-
-
Huber, S.1
Stahl, F.R.2
Schrader, J.3
-
40
-
-
79951898907
-
The regulation and functions of activin and follistatin in inflammation and immunity
-
Hedger MP, Winnall WR, Phillips D.J., et al The regulation and functions of activin and follistatin in inflammation and immunity. Vitam Horm 2011; 85: 255-297.
-
(2011)
Vitam Horm
, vol.85
, pp. 255-297
-
-
Hedger, M.P.1
Winnall, W.R.2
Phillips, D.J.3
-
41
-
-
0037446532
-
Regulation of activin A expression in mast cells and asthma: Its effect on the proliferation of human airway smooth muscle cells
-
Cho SH, Yao Z, Wang S.W., et al Regulation of activin A expression in mast cells and asthma: its effect on the proliferation of human airway smooth muscle cells. J Immunol 2003; 170: 4045-4052.
-
(2003)
J Immunol
, vol.170
, pp. 4045-4052
-
-
Cho, S.H.1
Yao, Z.2
Wang, S.W.3
-
42
-
-
0030581686
-
Effects of activin A on proliferation and differentiation of human lung fibroblasts
-
Ohga E, Matsuse T, Teramoto S., et al Effects of activin A on proliferation and differentiation of human lung fibroblasts. Biochem Biophys Res Commun 1996; 228: 391-396.
-
(1996)
Biochem Biophys Res Commun
, vol.228
, pp. 391-396
-
-
Ohga, E.1
Matsuse, T.2
Teramoto, S.3
-
43
-
-
77956628834
-
Overexpression of smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25
-
Gregory LG, Mathie SA, Walker S.A., et al Overexpression of smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25. Am J Respir Crit Care Med 2010; 182: 143-154.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 143-154
-
-
Gregory, L.G.1
Mathie, S.A.2
Walker, S.A.3
-
44
-
-
84871396240
-
The activin A antagonist follistatin inhibits asthmatic airway remodelling
-
Hardy CL, Nguyen HA, Mohamud R, et al The activin A antagonist follistatin inhibits asthmatic airway remodelling. Thorax 2013; 68: 9-18.
-
(2013)
Thorax
, vol.68
, pp. 9-18
-
-
Hardy, C.L.1
Nguyen, H.A.2
Mohamud, R.3
|