-
1
-
-
80052272493
-
Asthma: A simple concept but in reality a complex disease
-
Holgate ST. Asthma: a simple concept but in reality a complex disease. Eur J Clin Invest 2011;41:1339-52.
-
(2011)
Eur J Clin Invest
, vol.41
, pp. 1339-1352
-
-
Holgate, S.T.1
-
2
-
-
79951898907
-
The regulation and functions of activin and follistatin in inflammation and immunity
-
Hedger MP, Winnall WR, Phillips DJ, et al. The regulation and functions of activin and follistatin in inflammation and immunity. Vitam Horm 2011;85:255-97.
-
(2011)
Vitam Horm
, vol.85
, pp. 255-297
-
-
Hedger, M.P.1
Winnall, W.R.2
Phillips, D.J.3
-
3
-
-
84861653647
-
The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair
-
de Kretser DM, O'Hehir RE, Hardy CL, et al . The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair. Mol Cell Endocrinol 2012;359:101-6.
-
(2012)
Mol Cell Endocrinol
, vol.359
, pp. 101-106
-
-
De Kretser, D.M.1
O'Hehir, R.E.2
Hardy, C.L.3
-
4
-
-
0033852903
-
Regulation of activin's access to the cell: Why is mother nature such a control freak?
-
DOI 10.1002/1521-1878(200008)22:8<689::AID-BIES2>3.0.CO;2-5
-
Phillips DJ. Regulation of activin's access to the cell: why is mother nature such a control freak? Bioessays 2000;22:689-96. (Pubitemid 30613300)
-
(2000)
BioEssays
, vol.22
, Issue.8
, pp. 689-696
-
-
Phillips, D.J.1
-
5
-
-
29544448270
-
Activin A is an acute allergen-responsive cytokine and provides a link to TGF-beta-mediated airway remodeling in asthma
-
DOI 10.1016/j.jaci.2005.09.017, PII S0091674905020658
-
Karagiannidis C, Hense G, Martin C, et al. Activin A is an acute allergen-responsive cytokine and provides a link to TGF-beta-mediated airway remodeling in asthma. J Allergy Clin Immunol 2006;117:111-18. (Pubitemid 43017148)
-
(2006)
Journal of Allergy and Clinical Immunology
, vol.117
, Issue.1
, pp. 111-118
-
-
Karagiannidis, C.1
Hense, G.2
Martin, C.3
Epstein, M.4
Ruckert, B.5
Mantel, P.-Y.6
Menz, G.7
Uhlig, S.8
Blaser, K.9
Schmidt-Weber, C.B.10
-
6
-
-
33745645604
-
Follistatin is a candidate endogenous negative regulator of activin A in experimental allergic asthma
-
DOI 10.1111/j.1365-2222.2006.02523.x
-
Hardy CL, O'Connor AE, Yao J, et al. Follistatin is a candidate endogenous negative regulator of activin A in experimental allergic asthma. Clin Exp Allergy 2006;36:941-50. (Pubitemid 43972961)
-
(2006)
Clinical and Experimental Allergy
, vol.36
, Issue.7
, pp. 941-950
-
-
Hardy, C.L.1
O'Connor, A.E.2
Yao, J.3
Sebire, K.4
De Kretser, D.M.5
Rolland, J.M.6
Anderson, G.P.7
Phillips, D.J.8
O'Hehir, R.E.9
-
7
-
-
68149162210
-
Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease
-
Semitekolou M, Alissafi T, Aggelakopoulou M, et al. Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease. J Exp Med 2009;206:1769-85.
-
(2009)
J Exp Med
, vol.206
, pp. 1769-1785
-
-
Semitekolou, M.1
Alissafi, T.2
Aggelakopoulou, M.3
-
8
-
-
69549092367
-
Activin and transforming growth factor-beta signaling pathways are activated after allergen challenge in mild asthma
-
Kariyawasam HH, Pegorier S, Barkans J, et al. Activin and transforming growth factor-beta signaling pathways are activated after allergen challenge in mild asthma. J Allergy Clin Immunol 2009;124:454-62.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 454-462
-
-
Kariyawasam, H.H.1
Pegorier, S.2
Barkans, J.3
-
9
-
-
77953261745
-
Interleukin-13 regulates secretion of the tumor growth factor-{beta} superfamily cytokine activin A in allergic airway inflammation
-
Hardy CL, Lemasurier JS, Olsson F, et al. Interleukin-13 regulates secretion of the tumor growth factor-{beta} superfamily cytokine activin A in allergic airway inflammation. Am J Respir Cell Mol Biol 2010;42:667-75.
-
(2010)
Am J Respir Cell Mol Biol
, vol.42
, pp. 667-675
-
-
Hardy, C.L.1
Lemasurier, J.S.2
Olsson, F.3
-
10
-
-
0037446532
-
Regulation of activin A expression in mast cells and asthma: Its effect on the proliferation of human airway smooth muscle cells
-
Cho SH, Yao Z, Wang SW, et al. Regulation of activin A expression in mast cells and asthma: its effect on the proliferation of human airway smooth muscle cells. J Immunol 2003;170:4045-52. (Pubitemid 36428166)
-
(2003)
Journal of Immunology
, vol.170
, Issue.8
, pp. 4045-4052
-
-
Cho, S.H.1
Yao, Z.2
Wang, S.-W.3
Alban, R.F.4
Barbers, R.G.5
French, S.W.6
Oh, C.K.7
-
11
-
-
24944437072
-
Attenuation of bleomycin-induced pulmonary fibrosis by follistatin
-
DOI 10.1164/rccm.200412-1620OC
-
Aoki F, Kurabayashi M, Hasegawa Y, et al. Attenuation of bleomycin-induced pulmonary fi brosis by follistatin. Am J Respir Crit Care Med 2005;172:713-20. (Pubitemid 41324226)
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.172
, Issue.6
, pp. 713-720
-
-
Aoki, F.1
Kurabayashi, M.2
Hasegawa, Y.3
Kojima, I.4
-
12
-
-
34249792354
-
Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice
-
Le AV, Cho JY, Miller M, et al. Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice. J Immunol 2007;178:7310-16. (Pubitemid 46847458)
-
(2007)
Journal of Immunology
, vol.178
, Issue.11
, pp. 7310-7316
-
-
Le, A.V.1
Jae, Y.C.2
Miller, M.3
McElwain, S.4
Golgotiu, K.5
Broide, D.H.6
-
13
-
-
77956628834
-
Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25
-
Gregory LG, Mathie SA, Walker SA, et al. Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25. Am J Respir Crit Care Med 2010;182:143-54.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 143-154
-
-
Gregory, L.G.1
Mathie, S.A.2
Walker, S.A.3
-
14
-
-
1642372399
-
Prolonged allergen challenge in mice leads to persistent airway remodelling
-
DOI 10.1111/j.1365-2222.2004.01895.x
-
McMillan SJ, Lloyd CM. Prolonged allergen challenge in mice leads to persistent airway remodelling. Clin Exp Allergy 2004;34:497-507. (Pubitemid 38373015)
-
(2004)
Clinical and Experimental Allergy
, vol.34
, Issue.3
, pp. 497-507
-
-
McMillan, S.J.1
Lloyd, C.M.2
-
15
-
-
0035987319
-
Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma
-
DOI 10.1046/j.1365-2222.2002.01420.x
-
Kumar RK, Herbert C, Yang M, et al. Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma. Clin Exp Allergy 2002;32:1104-11. (Pubitemid 34779610)
-
(2002)
Clinical and Experimental Allergy
, vol.32
, Issue.7
, pp. 1104-1111
-
-
Kumar, R.K.1
Herbert, C.2
Yang, M.3
Koskinen, A.M.L.4
McKenzie, A.N.J.5
Foster, P.S.6
-
16
-
-
0036846991
-
Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation
-
Leigh R, Ellis R, Wattie J, et al. Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation. Am J Respir Cell Mol Biol 2002;27:526-35. (Pubitemid 35301806)
-
(2002)
American Journal of Respiratory Cell and Molecular Biology
, vol.27
, Issue.5
, pp. 526-535
-
-
Leigh, R.1
Ellis, R.2
Wattie, J.3
Southam, D.S.4
De Hoogh, M.5
Gauldie, J.6
O'Byrne, P.M.7
Inman, M.D.8
-
17
-
-
0038290216
-
Characterization of a mouse model of allergy to a major occupational latex glove allergen Hev b 5
-
DOI 10.1164/rccm.200209-1002OC
-
Hardy CL, Kenins L, Drew AC, et al. Characterization of a mouse model of allergy to a major occupational latex glove allergen Hev b 5. Am J Respir Crit Care Med 2003;167:1393-9. (Pubitemid 36609725)
-
(2003)
American Journal of Respiratory and Critical Care Medicine
, vol.167
, Issue.10
, pp. 1393-1399
-
-
Hardy, C.L.1
Kenins, L.2
Drew, A.C.3
Rolland, J.M.4
O'Hehir, R.E.5
-
18
-
-
0032999372
-
Serum activin A and follistatin concentrations during human pregnancy: A cross-sectional and longitudinal study
-
O'Connor AE, McFarlane JR, Hayward S, et al. Serum activin A and follistatin concentrations during human pregnancy: a cross-sectional and longitudinal study. Hum Reprod 1999;14:827-32. (Pubitemid 29131271)
-
(1999)
Human Reproduction
, vol.14
, Issue.3
, pp. 827-832
-
-
O'Connor, A.E.1
McFarlane, J.R.2
Hayward, S.3
Yohkaichiya, T.4
Groome, N.P.5
De Kretser, D.M.6
-
19
-
-
0032538279
-
Cells' perception of position in a concentration gradient
-
DOI 10.1016/S0092-8674(00)81747-X
-
Gurdon JB, Dyson S, St Johnston D. Cells' perception of position in a concentration gradient. Cell 1998;95:159-62. (Pubitemid 28473777)
-
(1998)
Cell
, vol.95
, Issue.2
, pp. 159-162
-
-
Gurdon, J.B.1
Dyson, S.2
St., J.D.3
-
20
-
-
33751507158
-
+ regulatory T cells
-
DOI 10.1084/jem.20060155
-
Strickland DH, Stumbles PA, Zosky GR, et al. Reversal of airway hyperresponsiveness by induction of airway mucosal CD4+CD25+ regulatory T cells. J Exp Med 2006;203:2649-60. (Pubitemid 44833341)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.12
, pp. 2649-2660
-
-
Strickland, D.H.1
Stumbles, P.A.2
Zosky, G.R.3
Subrata, L.S.4
Thomas, J.A.5
Turner, D.J.6
Sly, P.D.7
Holt, P.G.8
-
21
-
-
14044259923
-
Glomerular activin A overexpression is linked to fibrosis in anti-Thy1 glomerulonephritis
-
DOI 10.1093/ndt/gfh653
-
Gaedeke J, Boehler T, Budde K, et al. Glomerular activin A overexpression is linked to fibrosis in anti-Thy1 glomerulonephritis. Nephrol Dial Transplant 2005;20:319-28. (Pubitemid 40276887)
-
(2005)
Nephrology Dialysis Transplantation
, vol.20
, Issue.2
, pp. 319-328
-
-
Gaedeke, J.1
Boehler, T.2
Budde, K.3
Neumayer, H.-H.4
Peters, H.5
-
22
-
-
33644803768
-
Follistatin attenuates early liver fibrosis: Effects on hepatic stellate cell activation and hepatocyte apoptosis
-
Patella S, Phillips DJ, Tchongue J, et al. Follistatin attenuates early liver fibrosis: effects on hepatic stellate cell activation and hepatocyte apoptosis. Am J Physiol Gastrointest Liver Physiol 2006;290:G137-44.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
-
-
Patella, S.1
Phillips, D.J.2
Tchongue, J.3
-
23
-
-
12144285683
-
Elevated Levels of Activin A in Heart Failure: Potential Role in Myocardial Remodeling
-
DOI 10.1161/01.CIR.0000120704.97934.41
-
Yndestad A, Ueland T, Oie E, et al. Elevated levels of activin A in heart failure: potential role in myocardial remodeling. Circulation 2004;109:1379-85. (Pubitemid 38387824)
-
(2004)
Circulation
, vol.109
, Issue.11
, pp. 1379-1385
-
-
Yndestad, A.1
Ueland, T.2
Oie, E.3
Florholmen, G.4
Halvorsen, B.5
Attramadal, H.6
Simonsen, S.7
Froland, S.S.8
Gullestad, L.9
Christensen, G.10
Damas, J.K.11
Aukrust, P.12
-
24
-
-
0033214191
-
Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair
-
DOI 10.1093/emboj/18.19.5205
-
Munz B, Smola H, Engelhardt F, et al. Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair. EMBO J 1999;18:5205-15. (Pubitemid 29465571)
-
(1999)
EMBO Journal
, vol.18
, Issue.19
, pp. 5205-5215
-
-
Munz, B.1
Smola, H.2
Engelhardt, F.3
Bleuel, K.4
Brauchle, M.5
Lein, I.6
Evans, L.W.7
Huylebroeck, D.8
Balling, R.9
Werner, S.10
-
25
-
-
36248962703
-
Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease
-
DOI 10.1164/rccm.200702-334OC
-
Alcorn JF, Rinaldi LM, Jaffe EF, et al. Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease. Am J Respir Crit Care Med 2007;176:974-82. (Pubitemid 350127840)
-
(2007)
American Journal of Respiratory and Critical Care Medicine
, vol.176
, Issue.10
, pp. 974-982
-
-
Alcorn, J.F.1
Rinaldi, L.M.2
Jaffe, E.F.3
Van Loon, M.4
Bates, J.H.T.5
Janssen-Heininger, Y.M.W.6
Irvin, C.G.7
-
26
-
-
4043158506
-
Characterisation of the rapid release of activin A following acute lipopolysaccharide challenge in the ewe
-
DOI 10.1677/joe.0.1820069
-
Jones KL, De Kretser DM, Clarke IJ, et al. Characterisation of the rapid release of activin A following acute lipopolysaccharide challenge in the ewe. J Endocrinol 2004;182:69-80. (Pubitemid 39076903)
-
(2004)
Journal of Endocrinology
, vol.182
, Issue.1
, pp. 69-80
-
-
Jones, K.L.1
De Kretser, D.M.2
Clarke, I.J.3
Scheerlinck, J.-P.Y.4
Phillips, D.J.5
-
27
-
-
0035903306
-
1
-
DOI 10.1084/jem.194.6.809
-
Lee CG, Homer RJ, Zhu Z, et al. Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J Exp Med 2001;194:809-21. (Pubitemid 32983016)
-
(2001)
Journal of Experimental Medicine
, vol.194
, Issue.6
, pp. 809-821
-
-
Chun, G.L.1
Homer, R.J.2
Zhu, Z.3
Lanone, S.4
Wang, X.5
Koteliansky, V.6
Shipley, J.M.7
Gotwals, P.8
Noble, P.9
Chen, Q.10
Senior, R.M.11
Elias, J.A.12
-
28
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu Z, Homer RJ, Wang Z, et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999;103:779-88. (Pubitemid 29152623)
-
(1999)
Journal of Clinical Investigation
, vol.103
, Issue.6
, pp. 779-788
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
Chen, Q.4
Geba, G.P.5
Wang, J.6
Zhang, Y.7
Elias, J.A.8
-
29
-
-
0141869043
-
Activin A is an autocrine activator of rat pancreatic stellate cells: Potential therapeutic role of follistatin for pancreatic fibrosis
-
DOI 10.1136/gut.52.10.1487
-
Ohnishi N, Miyata T, Ohnishi H, et al. Activin A is an autocrine activator of rat pancreatic stellate cells: potential therapeutic role of follistatin for pancreatic fibrosis. Gut 2003;52:1487-93. (Pubitemid 37176730)
-
(2003)
Gut
, vol.52
, Issue.10
, pp. 1487-1493
-
-
Ohnishi, N.1
Miyata, T.2
Ohnishi, H.3
Yasuda, H.4
Tamada, K.5
Ueda, N.6
Mashima, H.7
Sugano, K.8
-
30
-
-
2542467762
-
The dependence of transforming growth factor-beta-induced collagen production on autocrine factor activin A in hepatic stellate cells
-
DOI 10.1210/en.2003-1663
-
Wada W, Kuwano H, Hasegawa Y, et al. The dependence of transforming growth factor-beta-induced collagen production on autocrine factor activin A in hepatic stellate cells. Endocrinology 2004;145:2753-9. (Pubitemid 38686224)
-
(2004)
Endocrinology
, vol.145
, Issue.6
, pp. 2753-2759
-
-
Wada, W.1
Kuwano, H.2
Hasegawa, Y.3
Kojima, I.4
-
31
-
-
0346734165
-
Activin A Is a Potent Activator of Renal Interstitial Fibroblasts
-
DOI 10.1097/01.ASN.0000103225.68136.E6
-
Yamashita S, Maeshima A, Kojima I, et al. Activin A is a potent activator of renal interstitial fibroblasts. J Am Soc Nephrol 2004;15:91-101. (Pubitemid 38020701)
-
(2004)
Journal of the American Society of Nephrology
, vol.15
, Issue.1
, pp. 91-101
-
-
Yamashita, S.1
Maeshima, A.2
Kojima, I.3
Nojima, Y.4
-
32
-
-
0032482928
-
Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo
-
DOI 10.1073/pnas.95.16.9337
-
Iemura S, Yamamoto TS, Takagi C, et al. Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo. Proc Natl Acad Sci U S A 1998;95:9337-42. (Pubitemid 28506232)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.16
, pp. 9337-9342
-
-
Iemura, S.-I.1
Yamamoto, T.S.2
Takagi, C.3
Uchiyama, H.4
Natsume, T.5
Shimasaki, S.6
Sugino, H.7
Ueno, N.8
-
33
-
-
33644858081
-
Structural basis for the inhibition of activin signalling by follistatin
-
DOI 10.1038/sj.emboj.7601000, PII 7601000
-
Harrington AE, Morris-Triggs SA, Ruotolo BT, et al. Structural basis for the inhibition of activin signalling by follistatin. EMBO J 2006;25:1035-45. (Pubitemid 43372117)
-
(2006)
EMBO Journal
, vol.25
, Issue.5
, pp. 1035-1045
-
-
Harrington, A.E.1
Morris-Triggs, S.A.2
Ruotolo, B.T.3
Robinson, C.V.4
Ohnuma, S.-I.5
Hyvonen, M.6
-
34
-
-
0034922101
-
Activation of the TGF-beta/activin-Smad2 pathway during allergic airway inflammation
-
Rosendahl A, Checchin D, Fehniger TE, et al. Activation of the TGF-beta/activin-Smad2 pathway during allergic airway inflammation. Am J Respir Cell Mol Biol 2001;25:60-8. (Pubitemid 32682706)
-
(2001)
American Journal of Respiratory Cell and Molecular Biology
, vol.25
, Issue.1
, pp. 60-68
-
-
Rosendahl, A.1
Checchin, D.2
Fehniger, T.E.3
Ten, D.P.4
Heldin, C.-H.5
Sideras, P.6
-
35
-
-
17844400081
-
Manipulation of allergen-induced airway remodeling by treatment with anti-TGF-beta antibody: Effect on the Smad signaling pathway
-
McMillan SJ, Xanthou G, Lloyd CM. Manipulation of allergen-induced airway remodeling by treatment with anti-TGF-beta antibody: effect on the Smad signaling pathway. J Immunol 2005;174:5774-80. (Pubitemid 40593221)
-
(2005)
Journal of Immunology
, vol.174
, Issue.9
, pp. 5774-5780
-
-
McMillan, S.J.1
Xanthou, G.2
Lloyd, C.M.3
|