Ginsenoside F2 induces apoptosis in humor gastric carcinoma cells through reactive oxygen species-mitochondria pathway and modulation of ASK-1/JNK signaling cascade in vitro and in vivo

Phytomedicine

Volumn 21, Issue 4, 2014, Pages 515-522

  Mao, Qian ^a   Zhang, Ping Hu ^b   Wang, Qiang ^b   Li, Song Lin ^a  

^a Jiangsu Provincial Hospital of Chinese Medicine   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; ASK 1 JNK; Mitochondria; ROS; Subcutaneous tumor model

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS SIGNAL REGULATED KINASE 1; CASPASE 3; CASPASE 9; CISPLATIN; CYTOCHROME C; GINSENOSIDE; GINSENOSIDE F2; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; APOPTOSIS SIGNAL REGULATING KINASE 1; MAP3K5 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CARCINOMA CELL; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PANAX NOTOGINSENG; PLANT LEAF; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STOMACH CANCER; STOMACH CARCINOMA; CARCINOMA; DRUG EFFECTS; DRUG SCREENING; METABOLISM; STOMACH NEOPLASMS; TUMOR CELL LINE;

APOPTOSIS; CARCINOMA; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; GINSENOSIDES; HUMANS; MAP KINASE KINASE KINASE 5; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES; STOMACH NEOPLASMS;

EID: 84897454073     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.10.013     Document Type: Article

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