Epigenetics Decouples Mutational from Environmental Robustness. Did It Also Facilitate Multicellularity?

PLoS Computational Biology

Volumn 10, Issue 3, 2014, Pages

  Gombar, Saurabh ^a   MacCarthy, Thomas ^a,b   Bergman, Aviv ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b Stony Brook University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY; GENES;

CELL DIFFERENTIATION; COMPLEX LIFE; DECOUPLINGS; ENVIRONMENTAL ROBUSTNESS; EPIGENETICS; GENE REGULATORY NETWORK MODEL; LIFE-FORMS; MOLECULAR LEVELS; MULTICELLULARITY; POLYCOMB;

PROTEINS;

POLYCOMB GROUP PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CHEMICAL PHENOMENA; CHROMATIN ASSEMBLY AND DISASSEMBLY; DECOUPLING; ENVIRONMENTAL FACTOR; EPIGENETICS; GENE MAPPING; GENE MUTATION; GENE REGULATORY NETWORK; GENETIC MODEL; GENOTYPE; HISTONE MODIFICATION; MOLECULAR EVOLUTION; MULTICELLULARITY; PHENOTYPE; POPULATION DYNAMICS;

ANIMALS; CELL DIFFERENTIATION; DNA MUTATIONAL ANALYSIS; DROSOPHILA MELANOGASTER; ENVIRONMENT; EPIGENESIS, GENETIC; EVOLUTION, MOLECULAR; GENE REGULATORY NETWORKS; GENE-ENVIRONMENT INTERACTION; GENETIC ASSOCIATION STUDIES; HISTONES; MUTATION; POLYCOMB-GROUP PROTEINS;

EID: 84897434836     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003450     Document Type: Article

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