메뉴 건너뛰기




Volumn 147, Issue 1, 1997, Pages 209-221

Chromatin insulator elements block the silencing of a target gene by the Drosophila polycomb response element (PRE) but allow trans interactions between PREs on different chromosomes

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BINDING SITE; CHROMATIN STRUCTURE; DROSOPHILA; EMBRYO DEVELOPMENT; GENE EXPRESSION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; SILENCER GENE; TRANSPOSON;

EID: 0030959781     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (182)

References (45)
  • 1
    • 0029879358 scopus 로고    scopus 로고
    • Cooperation at a distance between silencers and proto-silencers at the yeast HML locus
    • BOSCHERON, C., L. MAILLET, S. MARCAND, M. TSAI-PFLUGFELDER, S. M. GASSER et al., 1996 Cooperation at a distance between silencers and proto-silencers at the yeast HML locus. EMBO J. 15: 2184-2195.
    • (1996) EMBO J. , vol.15 , pp. 2184-2195
    • Boscheron, C.1    Maillet, L.2    Marcand, S.3    Tsai-Pflugfelder, M.4    Gasser, S.M.5
  • 2
    • 0029097707 scopus 로고
    • Modulation of enhancer-promoter interactions by insulators in the Drosophila embryo
    • CAI, H., and M. LEVINE, 1995 Modulation of enhancer-promoter interactions by insulators in the Drosophila embryo. Nature 376: 533-536.
    • (1995) Nature , vol.376 , pp. 533-536
    • Cai, H.1    Levine, M.2
  • 3
    • 0028321783 scopus 로고
    • A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression
    • CHAN, C. S., L. RASTELLI and V. PIRROTTA, 1994 A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression. EMBO J. 13: 2553-2564.
    • (1994) EMBO J. , vol.13 , pp. 2553-2564
    • Chan, C.S.1    Rastelli, L.2    Pirrotta, V.3
  • 4
    • 0029937208 scopus 로고    scopus 로고
    • Genetic modification of hetero-chromatic association and nuclear organization in Drosophila
    • CSINK, A. K. and S. HENIKOFF, 1996 Genetic modification of hetero-chromatic association and nuclear organization in Drosophila. Nature 381: 529-531.
    • (1996) Nature , vol.381 , pp. 529-531
    • Csink, A.K.1    Henikoff, S.2
  • 5
    • 0029943141 scopus 로고    scopus 로고
    • Perturbation of nuclear architecture by long-distance chromosome interactions
    • DERNBURG, A. F., K. W. BROMAN, J. C. FUNG, W. F. MARSHALL, J. PHILIPS, 1996 Perturbation of nuclear architecture by long-distance chromosome interactions. Cell 85: 745-759.
    • (1996) Cell , vol.85 , pp. 745-759
    • Dernburg, A.F.1    Broman, K.W.2    Fung, J.C.3    Marshall, W.F.4    Philips, J.5
  • 6
    • 0027296569 scopus 로고
    • Distance-independent inactivation of an enhancer by the suppressor of Hairy-wing DNA-binding protein of Drosophila
    • DORSETT, D., 1993 Distance-independent inactivation of an enhancer by the suppressor of Hairy-wing DNA-binding protein of Drosophila. Genetics 134: 1135-1144.
    • (1993) Genetics , vol.134 , pp. 1135-1144
    • Dorsett, D.1
  • 7
    • 0026578386 scopus 로고
    • Sequence of ses and scs′ Drosophila DNA fragments with boundary function in the control of gene expression
    • FARKAS, G., and A. UDVARDY, 1992 Sequence of ses and scs′ Drosophila DNA fragments with boundary function in the control of gene expression. Nucleic Acids Res. 20: 2604.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 2604
    • Farkas, G.1    Udvardy, A.2
  • 8
    • 0027312789 scopus 로고
    • Polyhomeotic regulatory sequences induce developmental regulator-dependent variegation and targeted P-element insertions in Drosophila
    • FAUVARQUE, M.-O., and J.-M. DURA, 1993 polyhomeotic regulatory sequences induce developmental regulator-dependent variegation and targeted P-element insertions in Drosophila. Genes Dev. 7: 1508-1520.
    • (1993) Genes Dev. , vol.7 , pp. 1508-1520
    • Fauvarque, M.-O.1    Dura, J.-M.2
  • 9
    • 0029007304 scopus 로고
    • The su(Hw) protein bound to gypsy sequences in one chromosome can repress enhancer-promoter interactions in the paired gene located in the other homolog
    • GEORGIEV, P.C., and V. G. CORCES, 1995 The su(Hw) protein bound to gypsy sequences in one chromosome can repress enhancer-promoter interactions in the paired gene located in the other homolog. Proc. Natl. Acad. Sci. USA 92: 5184-5188.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5184-5188
    • Georgiev, P.C.1    Corces, V.G.2
  • 10
    • 0030069203 scopus 로고    scopus 로고
    • Interaction between mutations in the suppressor of Hairy wing and modifier of mdg4 genes of Drosophila melanogaster affecting the phenotype of gypsy-induced mutations
    • GEORGIEV, P., and M. KOZYCINA, 1996 Interaction between mutations in the suppressor of Hairy wing and modifier of mdg4 genes of Drosophila melanogaster affecting the phenotype of gypsy-induced mutations. Genetics 142: 425-436.
    • (1996) Genetics , vol.142 , pp. 425-436
    • Georgiev, P.1    Kozycina, M.2
  • 11
    • 0028978180 scopus 로고
    • A Drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation
    • GERASIMOVA, T. I., D. A. GDULA, D. V. GERASIMOV, O. SIMONOVA and V. G. CORCES, 1995 A Drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation. Cell 82: 587-597.
    • (1995) Cell , vol.82 , pp. 587-597
    • Gerasimova, T.I.1    Gdula, D.A.2    Gerasimov, D.V.3    Simonova, O.4    Corces, V.G.5
  • 12
    • 0026738877 scopus 로고
    • DNA position-specific repression of transcription by a Drosophila zinc finger protein
    • GEYER, P. K., and V. G. CORCES, 1992 DNA position-specific repression of transcription by a Drosophila zinc finger protein. Genes Dev. 6: 1865-1873.
    • (1992) Genes Dev. , vol.6 , pp. 1865-1873
    • Geyer, P.K.1    Corces, V.G.2
  • 13
    • 0025335394 scopus 로고
    • Tissue-specific enhancers may act in trans on the gene located in the homologous chromosome: The molecular basis of transvection in Drosophila
    • GEYER, P. K., M. M. GREEN and V. G. CORCES, 1990 Tissue-specific enhancers may act in trans on the gene located in the homologous chromosome: the molecular basis of transvection in Drosophila. EMBO J. 9: 2247-2256
    • (1990) EMBO J. , vol.9 , pp. 2247-2256
    • Geyer, P.K.1    Green, M.M.2    Corces, V.G.3
  • 14
    • 0022801414 scopus 로고
    • On the molecular mechanism of gypsy-induced mutations at the yellow locus of Drosophila melanogaster
    • GEYER, P. K., C. SPANA and V. G. CORCES, 1986 On the molecular mechanism of gypsy-induced mutations at the yellow locus of Drosophila melanogaster. EMBO J. 5: 2657-2662.
    • (1986) EMBO J. , vol.5 , pp. 2657-2662
    • Geyer, P.K.1    Spana, C.2    Corces, V.G.3
  • 15
    • 0028814510 scopus 로고
    • Identification of Polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced
    • GINDHART, J. G., JR., and T. C. KAUFMAN, 1995 Identification of Polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced. Genetics 139: 797-814.
    • (1995) Genetics , vol.139 , pp. 797-814
    • Gindhart Jr., J.G.1    Kaufman, T.C.2
  • 16
    • 0029979801 scopus 로고    scopus 로고
    • Reduction of transcription by homologue asyuapsis in Drosophila imaginal discs
    • GOLDSBOROUGH, A. S., and T. B. KORNBERG, 1996 Reduction of transcription by homologue asyuapsis in Drosophila imaginal discs. Nature 381: 807-810.
    • (1996) Nature , vol.381 , pp. 807-810
    • Goldsborough, A.S.1    Kornberg, T.B.2
  • 17
    • 0030463741 scopus 로고    scopus 로고
    • Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex
    • HAGSTROM, K., M. MüLLER and P. SCHEDL, 1996 Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex. Genes Dev. 10: 3202-3215.
    • (1996) Genes Dev. , vol.10 , pp. 3202-3215
    • Hagstrom, K.1    Müller, M.2    Schedl, P.3
  • 18
    • 0026100193 scopus 로고
    • Repression of hsp70 heat shock gene transcription by the suppressor of Hairy wing protein of Drosophila melanogaster
    • HOLDRIDGE, C., and D. DORSETT, 1991 Repression of hsp70 heat shock gene transcription by the suppressor of Hairy wing protein of Drosophila melanogaster. Mol. Cell. Biol. 11: 1894-1900.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1894-1900
    • Holdridge, C.1    Dorsett, D.2
  • 19
    • 0025943096 scopus 로고
    • Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer
    • JACK, J., D. DORSETT, Y. DELOTTO and S. LIU, 1991 Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer. Development 113: 735-747.
    • (1991) Development , vol.113 , pp. 735-747
    • Jack, J.1    Dorsett, D.2    Delotto, Y.3    Liu, S.4
  • 20
    • 0029039049 scopus 로고
    • Regulatory regions of the homeotic gene proboscipedia are sensitive to chromosomal pairing
    • KAPOUN, A. M., and T. C. KAUFMAN, 1995 Regulatory regions of the homeotic gene proboscipedia are sensitive to chromosomal pairing. Genetics 140: 643-658.
    • (1995) Genetics , vol.140 , pp. 643-658
    • Kapoun, A.M.1    Kaufman, T.C.2
  • 21
    • 0028210606 scopus 로고
    • Unusual properties of regulatory DNA from the Drosophila engrailed gene: Three "pairing-sensitive" sites within a 1.6 kb region
    • KASSIS, J. A., 1994 Unusual properties of regulatory DNA from the Drosophila engrailed gene: three "pairing-sensitive" sites within a 1.6 kb region. Genetics 136: 1025-1038.
    • (1994) Genetics , vol.136 , pp. 1025-1038
    • Kassis, J.A.1
  • 22
    • 0026059058 scopus 로고
    • A fragment of engrailed regulatory DNA can mediate transvection of the white gene in Drosophila
    • KASSIS, J. A., E. P. VANSICKLE and S. M. SENSABAUGH, 1991 A fragment of engrailed regulatory DNA can mediate transvection of the white gene in Drosophila. Genetics 128: 751-761.
    • (1991) Genetics , vol.128 , pp. 751-761
    • Kassis, J.A.1    Vansickle, E.P.2    Sensabaugh, S.M.3
  • 23
    • 0026027982 scopus 로고
    • A position-effect assay for boundaries of higher order chromosomal domains
    • KELLUM, R., and P. SCHEDL, 1991 A position-effect assay for boundaries of higher order chromosomal domains. Cell 64: 941-950.
    • (1991) Cell , vol.64 , pp. 941-950
    • Kellum, R.1    Schedl, P.2
  • 24
    • 0026711089 scopus 로고
    • A group of ses elements function as domain boundaries in an enhancer-blocking assay
    • KELLUM, R., and P. SCHEDL, 1992 A group of ses elements function as domain boundaries in an enhancer-blocking assay. Mol. Cell. Biol. 12: 2424-2431.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2424-2431
    • Kellum, R.1    Schedl, P.2
  • 25
    • 0027421483 scopus 로고
    • The Drosophila melanogaster suppressor of Hairy-wing zinc finger protein has minimal effects on gene expression in Saccharomyces cerevisiae
    • KIM, J., B. SHEN, and D. DORSETT, 1993 The Drosophila melanogaster suppressor of Hairy-wing zinc finger protein has minimal effects on gene expression in Saccharomyces cerevisiae. Genetics 135: 343-355.
    • (1993) Genetics , vol.135 , pp. 343-355
    • Kim, J.1    Shen, B.2    Dorsett, D.3
  • 26
    • 0024632816 scopus 로고
    • Suppression in Drosophila: Su(Hw) and su(f) gene products interact with a region of gypsy (mdg4) regulating its transcriptional activity
    • MAZO, A. M., L. J. MIZROKHI, A. A. KARAVANOV, Y. A. SEDKOV, A. A. KRICHEVSKAJA et al., 1989 Suppression in Drosophila: su(Hw) and su(f) gene products interact with a region of gypsy (mdg4) regulating its transcriptional activity. EMBO J. 8: 903-912.
    • (1989) EMBO J. , vol.8 , pp. 903-912
    • Mazo, A.M.1    Mizrokhi, L.J.2    Karavanov, A.A.3    Sedkov, Y.A.4    Krichevskaja, A.A.5
  • 27
    • 0026701037 scopus 로고
    • Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster
    • MESSMER, S., A. FRANKE and R. PARO, 1992 Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster. Genes Dev. 6: 1241-1254.
    • (1992) Genes Dev. , vol.6 , pp. 1241-1254
    • Messmer, S.1    Franke, A.2    Paro, R.3
  • 28
    • 0027139910 scopus 로고
    • Mapping Polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin
    • ORLANDO, V., and R. PARO, 1993 Mapping Polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin. Cell 75: 1187-1198.
    • (1993) Cell , vol.75 , pp. 1187-1198
    • Orlando, V.1    Paro, R.2
  • 29
    • 0022774713 scopus 로고
    • The antherobithorax and bithorax mutations of the bithorax complex
    • PEIFER, M., and W. BENDER, 1986 The antherobithorax and bithorax mutations of the bithorax complex. EMBO J. 5: 2293-2304.
    • (1986) EMBO J. , vol.5 , pp. 2293-2304
    • Peifer, M.1    Bender, W.2
  • 30
    • 0024260258 scopus 로고
    • Vectors for P-mediated transformation in Drosophila
    • edited by R. L. RODRIGUEZ and D. T. DENHARDT. Butterworth, Boston
    • PIRROTTA, V., 1988 Vectors for P-mediated transformation in Drosophila, pp. 437-456, in Vectors: A Survey of Molecular Cloning Vectors and Their Uses, edited by R. L. RODRIGUEZ and D. T. DENHARDT. Butterworth, Boston.
    • (1988) Vectors: A Survey of Molecular Cloning Vectors and Their Uses , pp. 437-456
    • Pirrotta, V.1
  • 31
    • 0029100039 scopus 로고
    • Chromatin complexes regulating gene expression in Drosophila
    • PIRROTEA, V., 1995 Chromatin complexes regulating gene expression in Drosophila. Curr. Opin. Genet. Dev. 5: 466-472.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 466-472
    • Pirrotea, V.1
  • 32
    • 0028485216 scopus 로고
    • White gene expression, repressive chromatin domains and homeotic gene regulation
    • PIRROTTA, V., and L. RASTELLI, 1994 white gene expression, repressive chromatin domains and homeotic gene regulation. BioEssays 16: 549-556.
    • (1994) BioEssays , vol.16 , pp. 549-556
    • Pirrotta, V.1    Rastelli, L.2
  • 33
    • 0029790427 scopus 로고    scopus 로고
    • Hunchback independent silencing of late Ubx enhancers by a Polycomb Group Response Element
    • POUX, S., C. KOSTIC and V. PIRROTTA, 1996 Hunchback independent silencing of late Ubx enhancers by a Polycomb Group Response Element. EMBO J. 15: 4713-4722.
    • (1996) EMBO J. , vol.15 , pp. 4713-4722
    • Poux, S.1    Kostic, C.2    Pirrotta, V.3
  • 34
    • 0027402685 scopus 로고
    • The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position-effects
    • ROSEMAN, R. R., V. PIRROTTA and P. K. GEYER, 1993 The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position-effects. EMBO J. 12: 435-442.
    • (1993) EMBO J. , vol.12 , pp. 435-442
    • Roseman, R.R.1    Pirrotta, V.2    Geyer, P.K.3
  • 35
    • 0021111260 scopus 로고
    • Vectors for P element-mediated gene transfer in Drosophila
    • RUBIN, G. M., and A. C. SPRADLING, 1983 Vectors for P element-mediated gene transfer in Drosophila. Nucleic Acids Res. 11: 6341-6351.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 6341-6351
    • Rubin, G.M.1    Spradling, A.C.2
  • 36
    • 0029174794 scopus 로고
    • Effects of the su(Hw) insulator protein on the expression of the divergently transcribed Drosophila yolk protein genes
    • SCOTT, K. S., and P. K. GEYER, 1995 Effects of the su(Hw) insulator protein on the expression of the divergently transcribed Drosophila yolk protein genes. EMBO J. 14: 6258-6279.
    • (1995) EMBO J. , vol.14 , pp. 6258-6279
    • Scott, K.S.1    Geyer, P.K.2
  • 37
    • 0025113061 scopus 로고
    • DNA bending is a determinant of binding specificity for a Drosophila zinc finger protein
    • SPANA, C., and V. G. CORCES, 1990 DNA bending is a determinant of binding specificity for a Drosophila zinc finger protein. Genes Dev. 4: 1505-1515.
    • (1990) Genes Dev. , vol.4 , pp. 1505-1515
    • Spana, C.1    Corces, V.G.2
  • 38
    • 0028600559 scopus 로고
    • Sequences required for enhancer blocking activity of scs are located within two nuclease-hypersensitive regions
    • VAZQUEZ, J., and P. SCHEDL, 1994 Sequences required for enhancer blocking activity of scs are located within two nuclease-hypersensitive regions. EMBO J. 13: 5984-5993.
    • (1994) EMBO J. , vol.13 , pp. 5984-5993
    • Vazquez, J.1    Schedl, P.2
  • 40
    • 0027982060 scopus 로고
    • Two homeo domain proteins bind with similar specificity to a wide range of DNA sites in Drosophila embryos
    • WALTER, J., C. A. DEVEER and M. D. BIGGIN, 1994 Two homeo domain proteins bind with similar specificity to a wide range of DNA sites in Drosophila embryos. Genes Dev. 8: 1678-1692.
    • (1994) Genes Dev. , vol.8 , pp. 1678-1692
    • Walter, J.1    Deveer, C.A.2    Biggin, M.D.3
  • 41
    • 0029051646 scopus 로고
    • Transcription complex stability and chromatin dynamics in vivo
    • WIJGERDE, M., F. GROSVELD, and P. FRASER, 1995 Transcription complex stability and chromatin dynamics in vivo. Nature 377: 209-213.
    • (1995) Nature , vol.377 , pp. 209-213
    • Wijgerde, M.1    Grosveld, F.2    Fraser, P.3
  • 42
    • 0028960417 scopus 로고
    • A genetic analysis of the Suppressor 2 of zeste complex of Drosophila melanogaster
    • WU, C.-T. and M. HOWE, 1995 A genetic analysis of the Suppressor 2 of zeste complex of Drosophila melanogaster. Genetics 140: 139-181.
    • (1995) Genetics , vol.140 , pp. 139-181
    • Wu, C.-T.1    Howe, M.2
  • 43
    • 0029063587 scopus 로고
    • Visualization of chromosomal domains with boundary element-associated factor BEAF-32
    • ZHAO, K., C. M. HART and K. LAEMMLI, 1995 Visualization of chromosomal domains with boundary element-associated factor BEAF-32. Cell 81: 879-889.
    • (1995) Cell , vol.81 , pp. 879-889
    • Zhao, K.1    Hart, C.M.2    Laemmli, K.3
  • 44
    • 0028788045 scopus 로고
    • Drosophila Polycomb-group regulated chromatin inhibits the accessibility of a trans-activator to its target DNA
    • ZINK, D., and R. PARO, 1995 Drosophila Polycomb-group regulated chromatin inhibits the accessibility of a trans-activator to its target DNA. EMBO J. 14: 5660-5671.
    • (1995) EMBO J. , vol.14 , pp. 5660-5671
    • Zink, D.1    Paro, R.2
  • 45
    • 0025965064 scopus 로고
    • Direct interaction of the Polycomb protein with Antennapedia regulatory sequences in polytene chromosomes of Drosophila melanogaster
    • ZINK, B., Y. ENGSTRÖM, W. J. GEHRING and R. PARO, 1991 Direct interaction of the Polycomb protein with Antennapedia regulatory sequences in polytene chromosomes of Drosophila melanogaster. EMBO J. 10: 153-162.
    • (1991) EMBO J. , vol.10 , pp. 153-162
    • Zink, B.1    Engström, Y.2    Gehring, W.J.3    Paro, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.