Parent-of-Origin Effects Implicate Epigenetic Regulation of Experimental Autoimmune Encephalomyelitis and Identify Imprinted Dlk1 as a Novel Risk Gene

PLoS Genetics

Volumn 10, Issue 3, 2014, Pages

  Stridh, Pernilla ^a   Ruhrmann, Sabrina ^a   Bergman, Petra ^a   Thessén Hedreul, Mélanie ^a   Flytzani, Sevasti ^a   Da Beyeen, Amennainiel ^a   Gillett, Alan ^a   Krivosija, Nina ^a   Öckinger, Johan ^a   Ferguson Smith, Anne C ^b   Jagodic, Maja ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOME; CHROMOSOME 6; CONTROLLED STUDY; DISEASE PREDISPOSITION; DLK1 GENE; EPIGENETICS; EX VIVO STUDY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; EXTRACHROMOSOMAL INHERITANCE; FEMALE; GENE; GENE CLUSTER; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCUS; HERITABILITY; IGF2 GENE; IN VITRO STUDY; INHERITANCE; MALE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PATHOGENESIS; QUANTITATIVE TRAIT LOCUS; RAT; RISK ASSESSMENT; RISK FACTOR; Y CHROMOSOME; ANIMAL; GENETIC EPIGENESIS; GENETIC PREDISPOSITION; GENETICS; GENOME IMPRINTING; HUMAN; PATHOLOGY; TRANSGENIC MOUSE;

DLK1 PROTEIN, HUMAN; MEMBRANE PROTEIN; SIGNAL PEPTIDE;

ALLELES; ANIMALS; CHROMOSOMES, HUMAN, PAIR 6; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; EPIGENESIS, GENETIC; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOMIC IMPRINTING; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; RATS; RISK FACTORS;

EID: 84897428252     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004265     Document Type: Article

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